Details for: UROS
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 101.2839
Cell Significance Index: -25.6900 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 77.1410
Cell Significance Index: -36.4200 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 73.7464
Cell Significance Index: -29.9600 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 65.1846
Cell Significance Index: -33.5300 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 54.4542
Cell Significance Index: -36.5400 - Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 33.3665
Cell Significance Index: -5.1900 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 31.4744
Cell Significance Index: -30.0500 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 24.5913
Cell Significance Index: -30.3200 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 9.4219
Cell Significance Index: -25.2400 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 9.2371
Cell Significance Index: -36.4500 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 8.1818
Cell Significance Index: -25.1300 - Cell Name: granulosa cell (CL0000501)
Fold Change: 1.6062
Cell Significance Index: 42.2400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.5101
Cell Significance Index: 90.6600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.2920
Cell Significance Index: 60.2400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 1.0641
Cell Significance Index: 55.8700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 1.0489
Cell Significance Index: 122.2400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.0109
Cell Significance Index: 912.7400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.8963
Cell Significance Index: 179.8000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.8392
Cell Significance Index: 11.4500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6300
Cell Significance Index: 102.4700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.5620
Cell Significance Index: 306.9200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.5493
Cell Significance Index: 75.4400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.5076
Cell Significance Index: 31.9900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.5008
Cell Significance Index: 32.3100 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.4740
Cell Significance Index: 10.2700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.4177
Cell Significance Index: 149.8300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.3752
Cell Significance Index: 67.6400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.3689
Cell Significance Index: 73.2100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.3194
Cell Significance Index: 37.6700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.3077
Cell Significance Index: 37.8400 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.2909
Cell Significance Index: 37.2900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.2901
Cell Significance Index: 12.8300 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.2501
Cell Significance Index: 9.4700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.2201
Cell Significance Index: 6.1500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2180
Cell Significance Index: 96.3800 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.2156
Cell Significance Index: 27.8500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.1978
Cell Significance Index: 4.1400 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.1716
Cell Significance Index: 5.0400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.1540
Cell Significance Index: 7.2400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.1536
Cell Significance Index: 7.9800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1513
Cell Significance Index: 6.8600 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.1292
Cell Significance Index: 9.1400 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.1245
Cell Significance Index: 4.3300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1236
Cell Significance Index: 85.4700 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0994
Cell Significance Index: 18.9100 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.0668
Cell Significance Index: 4.9800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0513
Cell Significance Index: 3.9400 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.0495
Cell Significance Index: 0.5900 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0481
Cell Significance Index: 90.5100 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 0.0298
Cell Significance Index: 0.2500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0269
Cell Significance Index: 2.6600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0193
Cell Significance Index: 26.2300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0069
Cell Significance Index: 12.7700 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0062
Cell Significance Index: 4.5300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0049
Cell Significance Index: 3.6800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0029
Cell Significance Index: 4.4700 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0096
Cell Significance Index: -0.1600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0120
Cell Significance Index: -7.6400 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0252
Cell Significance Index: -4.3100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0326
Cell Significance Index: -24.1600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0346
Cell Significance Index: -3.5300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0363
Cell Significance Index: -16.4800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0446
Cell Significance Index: -25.1300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0645
Cell Significance Index: -40.2500 - Cell Name: peg cell (CL4033014)
Fold Change: -0.0697
Cell Significance Index: -1.6100 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0779
Cell Significance Index: -2.0900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0873
Cell Significance Index: -2.3300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0918
Cell Significance Index: -2.9400 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.0984
Cell Significance Index: -1.0700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1022
Cell Significance Index: -29.4000 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1108
Cell Significance Index: -2.3600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1113
Cell Significance Index: -6.8400 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1278
Cell Significance Index: -4.4900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1328
Cell Significance Index: -19.3100 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1450
Cell Significance Index: -3.7100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1639
Cell Significance Index: -11.0200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1657
Cell Significance Index: -18.9800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1808
Cell Significance Index: -38.0900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.1867
Cell Significance Index: -3.2000 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.2103
Cell Significance Index: -11.8000 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2303
Cell Significance Index: -12.0000 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.2449
Cell Significance Index: -6.9900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2722
Cell Significance Index: -21.5600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3314
Cell Significance Index: -34.5100 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.3594
Cell Significance Index: -7.8700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.4219
Cell Significance Index: -11.3100 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.4870
Cell Significance Index: -4.4900 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.5290
Cell Significance Index: -6.0100 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.5654
Cell Significance Index: -12.0000 - Cell Name: melanocyte of skin (CL1000458)
Fold Change: -0.5847
Cell Significance Index: -8.2000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.6002
Cell Significance Index: -36.8000 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.6023
Cell Significance Index: -7.4700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.6121
Cell Significance Index: -16.6600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.6158
Cell Significance Index: -15.8300 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.6408
Cell Significance Index: -9.4600 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.6684
Cell Significance Index: -16.0300 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.6864
Cell Significance Index: -21.8600 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.7021
Cell Significance Index: -20.6800 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.7074
Cell Significance Index: -23.1600 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.7177
Cell Significance Index: -7.4300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 435414242
Symbol: HEM4_HUMAN
Name: Uroporphyrinogen-III synthase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3174619
Title: Human uroporphyrinogen III synthase: molecular cloning, nucleotide sequence, and expression of a full-length cDNA.
PubMed ID: 3174619
PubMed ID: 11112350
Title: Human uroporphyrinogen-III synthase: genomic organization, alternative promoters, and erythroid-specific expression.
PubMed ID: 11112350
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8829650
Title: Molecular basis of congenital erythropoietic porphyria: mutations in the human uroporphyrinogen III synthase gene.
PubMed ID: 8829650
DOI: 10.1002/(sici)1098-1004(1996)7:3<187::aid-humu1>3.0.co;2-8
PubMed ID: 18004775
Title: Human uroporphyrinogen III synthase: NMR-based mapping of the active site.
PubMed ID: 18004775
DOI: 10.1002/prot.21755
PubMed ID: 11689424
Title: Crystal structure of human uroporphyrinogen III synthase.
PubMed ID: 11689424
PubMed ID: 2331520
Title: Point mutations in the uroporphyrinogen III synthase gene in congenital erythropoietic porphyria (Gunther's disease).
PubMed ID: 2331520
PubMed ID: 1733834
Title: Heterogeneity of mutations in the uroporphyrinogen III synthase gene in congenital erythropoietic porphyria.
PubMed ID: 1733834
DOI: 10.1007/bf00197267
PubMed ID: 1737856
Title: Congenital erythropoietic porphyria: identification and expression of exonic mutations in the uroporphyrinogen III synthase gene.
PubMed ID: 1737856
DOI: 10.1172/jci115637
PubMed ID: 7860775
Title: Congenital erythropoietic porphyria: identification and expression of 10 mutations in the uroporphyrinogen III synthase gene.
PubMed ID: 7860775
DOI: 10.1172/jci117742
PubMed ID: 8655129
Title: A novel point mutation in congenital erythropoietic porphyria in two members of Japanese family.
PubMed ID: 8655129
DOI: 10.1007/bf02281859
PubMed ID: 9188670
Title: Novel point mutation in the uroporphyrinogen III synthase gene causes congenital erythropoietic porphyria of a Japanese family.
PubMed ID: 9188670
DOI: 10.1002/(sici)1096-8628(19970613)70:3<299::aid-ajmg16>3.0.co;2-g
PubMed ID: 9834209
Title: Congenital erythropoietic porphyria successfully treated by allogeneic bone marrow transplantation.
PubMed ID: 9834209
PubMed ID: 9803266
Title: C73R is a hotspot mutation in the uroporphyrinogen III synthase gene in congenital erythropoietic porphyria.
PubMed ID: 9803266
PubMed ID: 11121156
Title: Congenital erythropoietic porphyria: a novel homozygous mutation in a Japanese patient.
PubMed ID: 11121156
PubMed ID: 12060141
Title: Congenital erythropoietic porphyria: identification and expression of eight novel mutations in the uroporphyrinogen III synthase gene.
PubMed ID: 12060141
PubMed ID: 15304101
Title: Congenital erythropoietic porphyria: report of a novel mutation with absence of clinical manifestations in a homozygous mutant sibling.
PubMed ID: 15304101
PubMed ID: 21653323
Title: ALAS2 acts as a modifier gene in patients with congenital erythropoietic porphyria.
PubMed ID: 21653323
PubMed ID: 22350154
Title: Mutational analysis of uroporphyrinogen III cosynthase gene in Iranian families with congenital erythropoietic porphyria.
PubMed ID: 22350154
Sequence Information:
- Length: 265
- Mass: 28628
- Checksum: CEF171401361F61E
- Sequence:
MKVLLLKDAK EDDCGQDPYI RELGLYGLEA TLIPVLSFEF LSLPSFSEKL SHPEDYGGLI FTSPRAVEAA ELCLEQNNKT EVWERSLKEK WNAKSVYVVG NATASLVSKI GLDTEGETCG NAEKLAEYIC SRESSALPLL FPCGNLKREI LPKALKDKGI AMESITVYQT VAHPGIQGNL NSYYSQQGVP ASITFFSPSG LTYSLKHIQE LSGDNIDQIK FAAIGPTTAR ALAAQGLPVS CTAESPTPQA LATGIRKALQ PHGCC
Genular Protein ID: 3741145343
Symbol: A0A3B3ISM6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 292
- Mass: 31662
- Checksum: E1B2F827EDD4DD86
- Sequence:
MKVLLLKDAK EDDCGQDPYI RELGLYGLEA TLIPVLSFEF LSLPSFSEKL SHPEDYGGLI FTSPRAVEAA ELCLEQNNKT EVWERSLKEK WNAKSVYVVG NATASLVSKI GLDTEGETCG NAEKLAEYIC SRESSALPLL FPCGNLKREI LPKALKDKGI AMESITVYQT VAHPGIQGNL NSYYSQQGVP ASITFFSPSG LTYSLKHIQE LSGDNIDQIK TQGPQHPKKN CLQLEPLRKD CTDTAVMFAA IGPTTARALA AQGLPVSCTA ESPTPQALAT GIRKALQPHG CC
Genular Protein ID: 358411946
Symbol: A0A0S2Z5C5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 26871637
Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
PubMed ID: 26871637
Sequence Information:
- Length: 238
- Mass: 25707
- Checksum: 8E6D4FAEE863CB22
- Sequence:
MKVLLLKDAK EDDCGQDPYI RELGLYGLEA TLIPVLSFEF LSLPSFSEKL SHPEDYGGLI FTSPRAVEAA ELCLEQNNKT EVWERSLKEK WNAKSVYVVG NATASLVSKI GLDTEGETCG NAEKLAEYIC SRIAMESITV YQTVAHPGIQ GNLNSYYSQQ GVPASITFFS PSGLTYSLKH IQELSGDNID QIKFAAIGPT TARALAAQGL PVSCTAESPT PQALATGIRK ALQPHGCC
Genular Protein ID: 2244467587
Symbol: A0A3B3ITJ2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 265
- Mass: 28742
- Checksum: 02E7367F3441EE9D
- Sequence:
MKVLLLKDAK EDDCGQDPYI RELGLYGLEA TLIPVLSFEF LSLPSFSEKL SHPEDYGGLI FTSPRAVEAA ELCLEQNNKT EVWERSLKEK WNAKSVYVVG NATASLVSKI GLDTEGETCG NAEKLAEYIC SRIAMESITV YQTVAHPGIQ GNLNSYYSQQ GVPASITFFS PSGLTYSLKH IQELSGDNID QIKTQGPQHP KKNCLQLEPL RKDCTDTAVM FAAIGPTTAR ALAAQGLPVS CTAESPTPQA LATGIRKALQ PHGCC
Genular Protein ID: 305624272
Symbol: Q5T3L8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11181995
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 139
- Mass: 15369
- Checksum: 473CF085DB483901
- Sequence:
MKVLLLKDAK EDDCGQDPYI RELGLYGLEA TLIPVLSFEF LSLPSFSEKL SHPEDYGGLI FTSPRAVEAA ELCLEQNNKT EVWERSLKEK WNAKSVYVVG NATASLVSKI GLDTEGETCG NAEKLAEYIC SSEEVKGIF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.