Details for: VLDLR

Gene ID: 7436

Symbol: VLDLR

Ensembl ID: ENSG00000147852

Description: very low density lipoprotein receptor

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 113.9540
    Cell Significance Index: -17.7300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 69.5070
    Cell Significance Index: -17.6300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 33.7717
    Cell Significance Index: -13.7200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 14.4369
    Cell Significance Index: -17.8000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 14.3075
    Cell Significance Index: -13.6600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 6.5401
    Cell Significance Index: -17.5200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 3.8093
    Cell Significance Index: -11.7000
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.4680
    Cell Significance Index: 18.8000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.3112
    Cell Significance Index: 28.7100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.2201
    Cell Significance Index: 76.9000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.1376
    Cell Significance Index: 24.6500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.9702
    Cell Significance Index: 74.4600
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.7446
    Cell Significance Index: 11.2200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.5930
    Cell Significance Index: 26.2300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.5836
    Cell Significance Index: 22.1000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.5365
    Cell Significance Index: 34.6200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4982
    Cell Significance Index: 94.8100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.4622
    Cell Significance Index: 5.5100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4567
    Cell Significance Index: 20.7000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.4463
    Cell Significance Index: 243.7500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.3491
    Cell Significance Index: 19.5900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3305
    Cell Significance Index: 17.1700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3218
    Cell Significance Index: 64.5600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2889
    Cell Significance Index: 103.6400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2614
    Cell Significance Index: 236.0600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.2168
    Cell Significance Index: 3.2000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.1953
    Cell Significance Index: 5.0200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1774
    Cell Significance Index: 28.8500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1596
    Cell Significance Index: 7.4400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1480
    Cell Significance Index: 14.6500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1273
    Cell Significance Index: 17.4800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1180
    Cell Significance Index: 81.6100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0978
    Cell Significance Index: 10.6400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0880
    Cell Significance Index: 15.0200
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.0844
    Cell Significance Index: 1.3900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0813
    Cell Significance Index: 2.1700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0625
    Cell Significance Index: 3.2800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.0617
    Cell Significance Index: 1.7600
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.0564
    Cell Significance Index: 0.7000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0465
    Cell Significance Index: 8.3800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0407
    Cell Significance Index: 1.0700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0382
    Cell Significance Index: 0.6400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0114
    Cell Significance Index: 15.5600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0059
    Cell Significance Index: 0.1700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0055
    Cell Significance Index: 0.3300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0040
    Cell Significance Index: 7.5200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0028
    Cell Significance Index: 1.2500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0003
    Cell Significance Index: -0.5600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0019
    Cell Significance Index: -1.4300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0022
    Cell Significance Index: -1.3700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0025
    Cell Significance Index: -0.3700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0027
    Cell Significance Index: -4.1500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0028
    Cell Significance Index: -2.0600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0049
    Cell Significance Index: -3.0300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0056
    Cell Significance Index: -0.1200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0060
    Cell Significance Index: -0.2100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0067
    Cell Significance Index: -0.4600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0079
    Cell Significance Index: -0.9000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0128
    Cell Significance Index: -9.6800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0141
    Cell Significance Index: -7.9400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0209
    Cell Significance Index: -1.2800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0221
    Cell Significance Index: -1.3600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0232
    Cell Significance Index: -1.5600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0268
    Cell Significance Index: -5.6400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0277
    Cell Significance Index: -12.2600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0286
    Cell Significance Index: -5.6800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0331
    Cell Significance Index: -4.0800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0342
    Cell Significance Index: -4.3800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0370
    Cell Significance Index: -0.9300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0420
    Cell Significance Index: -4.8900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0426
    Cell Significance Index: -12.2500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0429
    Cell Significance Index: -1.2000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0466
    Cell Significance Index: -4.7600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0502
    Cell Significance Index: -5.7300
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0852
    Cell Significance Index: -2.0800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0987
    Cell Significance Index: -12.7500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1065
    Cell Significance Index: -5.0100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1158
    Cell Significance Index: -3.7100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1438
    Cell Significance Index: -16.9600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1444
    Cell Significance Index: -3.0000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1529
    Cell Significance Index: -15.9200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1722
    Cell Significance Index: -12.1800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1839
    Cell Significance Index: -9.5800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1874
    Cell Significance Index: -13.9700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1951
    Cell Significance Index: -15.4500
  • Cell Name: theca cell (CL0000503)
    Fold Change: -0.2128
    Cell Significance Index: -1.2500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.2199
    Cell Significance Index: -3.0000
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.2220
    Cell Significance Index: -5.1300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2338
    Cell Significance Index: -6.3700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2445
    Cell Significance Index: -4.1900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2700
    Cell Significance Index: -7.7400
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.2830
    Cell Significance Index: -4.4900
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.3003
    Cell Significance Index: -2.3200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.3081
    Cell Significance Index: -7.3900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3326
    Cell Significance Index: -10.8900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.3371
    Cell Significance Index: -6.5800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3465
    Cell Significance Index: -12.7200
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.3479
    Cell Significance Index: -6.4300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3496
    Cell Significance Index: -12.1500
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.3501
    Cell Significance Index: -4.9100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** The VLDLR gene is a single-copy gene located on chromosome 1p31.3 in humans. It encodes a transmembrane receptor protein with 7-8 transmembrane domains, which is homologous to the LDL receptor. The VLDLR protein has a high affinity for VLDL particles and is involved in their endocytosis and degradation. The receptor is composed of two extracellular domains, two transmembrane domains, and one cytoplasmic domain. The extracellular domains bind to VLDL particles, while the transmembrane domains facilitate the internalization of the receptor-VLDL complex. **Pathways and Functions** VLDLR is involved in various signaling pathways, including: 1. **Lipid Metabolism**: VLDLR plays a crucial role in the uptake and clearance of VLDL particles, which are rich in triglycerides and cholesterol. This process helps to regulate lipid levels in the bloodstream and maintain cholesterol homeostasis. 2. **Axon Guidance**: VLDLR has been shown to be involved in axon guidance and neuronal development, particularly in the development of the nervous system. 3. **Reelin Signaling Pathway**: VLDLR is a component of the reelin signaling pathway, which is involved in neuronal migration and development. 4. **Receptor-Mediated Endocytosis**: VLDLR is a receptor-mediated endocytosis receptor, which means that it can internalize ligands through a process of receptor-mediated endocytosis. **Clinical Significance** Dysregulation of VLDLR has been implicated in various diseases, including: 1. **Atherosclerosis**: Elevated levels of VLDL particles have been linked to the development of atherosclerosis, a condition characterized by the buildup of plaque in the arteries. 2. **Cardiovascular Disease**: VLDLR has been implicated in the development of cardiovascular disease, including heart attacks and strokes. 3. **Neurodegenerative Disorders**: VLDLR has been linked to neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. 4. **Diabetes**: VLDLR has been implicated in the development of type 2 diabetes, a condition characterized by insulin resistance and hyperglycemia. In conclusion, the VLDLR gene plays a crucial role in lipid metabolism, axon guidance, and neuronal development. Dysregulation of VLDLR has been implicated in various diseases, including atherosclerosis, cardiovascular disease, neurodegenerative disorders, and diabetes. Further research is needed to fully understand the mechanisms by which VLDLR regulates lipid metabolism and its role in disease pathogenesis.

Genular Protein ID: 2357207309

Symbol: VLDLR_HUMAN

Name: Very low-density lipoprotein receptor

UniProtKB Accession Codes:

P98155 B2RMZ7 D3DRH6 Q5VVF6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 6 EMBL 11 EMDB 3 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 26 Gene3D 3 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 6 PIR 1 PRINTS 1 PRO 1 PROSITE 7 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 3 RefSeq 2 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8128315

Title: Cloning of a cDNA encoding a putative human very low density lipoprotein/apolipoprotein E receptor and assignment of the gene to chromosome 9pter-p23.

PubMed ID: 8128315

DOI: 10.1007/bf01233382

PubMed ID: 8069294

Title: Characterization and tissue-specific expression of the human 'very low density lipoprotein (VLDL) receptor' mRNA.

PubMed ID: 8069294

DOI: 10.1093/hmg/3.4.531

PubMed ID: 8294473

Title: Structure, chromosome location, and expression of the human very low density lipoprotein receptor gene.

PubMed ID: 8294473

DOI: 10.1016/s0021-9258(17)42151-x

PubMed ID: 8020981

Title: Human very-low-density lipoprotein receptor complementary DNA and deduced amino acid sequence and localization of its gene (VLDLR) to chromosome band 9p24 by fluorescence in situ hybridization.

PubMed ID: 8020981

DOI: 10.1006/geno.1994.1171

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12857919

Title: A cellular receptor of human rhinovirus type 2, the very-low-density lipoprotein receptor, binds to two neighboring proteins of the viral capsid.

PubMed ID: 12857919

DOI: 10.1128/jvi.77.15.8504-8511.2003

PubMed ID: 17330141

Title: The Pafah1b complex interacts with the reelin receptor VLDLR.

PubMed ID: 17330141

DOI: 10.1371/journal.pone.0000252

PubMed ID: 18039658

Title: The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2.

PubMed ID: 18039658

DOI: 10.1074/jbc.m708098200

PubMed ID: 20427281

Title: The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2.

PubMed ID: 20427281

DOI: 10.1074/jbc.m110.123729

PubMed ID: 23701949

Title: Stx5 is a novel interactor of VLDL-R to affect its intracellular trafficking and processing.

PubMed ID: 23701949

DOI: 10.1016/j.yexcr.2013.05.010

PubMed ID: 24381170

Title: Clusterin is a ligand for apolipoprotein E receptor 2 (ApoER2) and very low density lipoprotein receptor (VLDLR) and signals via the Reelin-signaling pathway.

PubMed ID: 24381170

DOI: 10.1074/jbc.m113.529271

PubMed ID: 30873003

Title: Differential Action of Reelin on Oligomerization of ApoER2 and VLDL Receptor in HEK293 Cells Assessed by Time-Resolved Anisotropy and Fluorescence Lifetime Imaging Microscopy.

PubMed ID: 30873003

DOI: 10.3389/fnmol.2019.00053

PubMed ID: 34929721

Title: VLDLR and ApoER2 are receptors for multiple alphaviruses.

PubMed ID: 34929721

DOI: 10.1038/s41586-021-04326-0

PubMed ID: 15064754

Title: X-ray structure of a minor group human rhinovirus bound to a fragment of its cellular receptor protein.

PubMed ID: 15064754

DOI: 10.1038/nsmb753

PubMed ID: 10391209

Title: Characterization of single-nucleotide polymorphisms in coding regions of human genes.

PubMed ID: 10391209

DOI: 10.1038/10290

PubMed ID: 16080122

Title: Homozygous deletion of the very low density lipoprotein receptor gene causes autosomal recessive cerebellar hypoplasia with cerebral gyral simplification.

PubMed ID: 16080122

DOI: 10.1086/444400

Sequence Information:

  • Length: 873
  • Mass: 96098
  • Checksum: 8BAC29438A78C2B8
  • Sequence:
    • MGTSALWALW LLLALCWAPR ESGATGTGRK AKCEPSQFQC TNGRCITLLW KCDGDEDCVD 
GSDEKNCVKK TCAESDFVCN NGQCVPSRWK CDGDPDCEDG SDESPEQCHM RTCRIHEISC 
GAHSTQCIPV SWRCDGENDC DSGEDEENCG NITCSPDEFT CSSGRCISRN FVCNGQDDCS 
DGSDELDCAP PTCGAHEFQC STSSCIPISW VCDDDADCSD QSDESLEQCG RQPVIHTKCP 
ASEIQCGSGE CIHKKWRCDG DPDCKDGSDE VNCPSRTCRP DQFECEDGSC IHGSRQCNGI 
RDCVDGSDEV NCKNVNQCLG PGKFKCRSGE CIDISKVCNQ EQDCRDWSDE PLKECHINEC 
LVNNGGCSHI CKDLVIGYEC DCAAGFELID RKTCGDIDEC QNPGICSQIC INLKGGYKCE 
CSRGYQMDLA TGVCKAVGKE PSLIFTNRRD IRKIGLERKE YIQLVEQLRN TVALDADIAA 
QKLFWADLSQ KAIFSASIDD KVGRHVKMID NVYNPAAIAV DWVYKTIYWT DAASKTISVA 
TLDGTKRKFL FNSDLREPAS IAVDPLSGFV YWSDWGEPAK IEKAGMNGFD RRPLVTADIQ 
WPNGITLDLI KSRLYWLDSK LHMLSSVDLN GQDRRIVLKS LEFLAHPLAL TIFEDRVYWI 
DGENEAVYGA NKFTGSELAT LVNNLNDAQD IIVYHELVQP SGKNWCEEDM ENGGCEYLCL 
PAPQINDHSP KYTCSCPSGY NVEENGRDCQ STATTVTYSE TKDTNTTEIS ATSGLVPGGI 
NVTTAVSEVS VPPKGTSAAW AILPLLLLVM AAVGGYLMWR NWQHKNMKSM NFDNPVYLKT 
TEEDLSIDIG RHSASVGHTY PAISVVSTDD DLA

Genular Protein ID: 410004354

Symbol: A0A7P0T9P7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A7P0T9P7

Database IDs:

ARBA 9 AlphaFoldDB 1 Bgee 1 CDD 2 CTD 1 DisGeNET 1 EMBL 1 Ensembl 2 GO 3 Gene3D 3 GeneTree 1 HGNC 1 InterPro 12 NCBI Taxonomy 1 PANTHER 2 PRINTS 1 PROSITE 8 PROSITE-ProRule 3 PeptideAtlas 2 Pfam 5 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 4 SMR 1 SUPFAM 3

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 804
  • Mass: 88875
  • Checksum: 2CFA90928287050D
  • Sequence:
    • MGTSALWALW LLLALCWAPR ESGATGTGRK AKCEPSQFQC TNGRCITLLW KCDGDEDCVD 
GSDEKNCVKK TCAESDFVCN NGQCVPSRWK CDGDPDCEDG SDESPEQCRN ITCSPDEFTC 
SSGRCISRNF VCNGQDDCSD GSDELDCAPP TCGAHEFQCS TSSCIPISWV CDDDADCSDQ 
SDESLEQCGR QPVIHTKCPA SEIQCGSGEC IHKKWRCDGD PDCKDGSDEV NCPSRTCRPD 
QFECEDGSCI HGSRQCNGIR DCVDGSDEVN CKNVNQCLGP GKFKCRSGEC IDISKVCNQE 
QDCRDWSDEP LKECHINECL VNNGGCSHIC KDLVIGYECD CAAGFELIDR KTCGDIDECQ 
NPGICSQICI NLKGGYKCEC SRGYQMDLAT GVCKAVGKEP SLIFTNRRDI RKIGLERKEY 
IQLVEQLRNT VALDADIAAQ KLFWADLSQK AIFSASIDDK VGRHVKMIDN VYNPAAIAVD 
WVYKTIYWTD AASKTISVAT LDGTKRKFLF NSDLREPASI AVDPLSGFVY WSDWGEPAKI 
EKAGMNGFDR RPLVTADIQW PNGITLDLIK SRLYWLDSKL HMLSSVDLNG QDRRIVLKSL 
EFLAHPLALT IFEDRVYWID GENEAVYGAN KFTGSELATL VNNLNDAQDI IVYHELVQPS 
GKNWCEEDME NGGCEYLCLP APQINDHSPK YTCSCPSGYN VEENGRDCQR INVTTAVSEV 
SVPPKGTSAA WAILPLLLLV MAAVGGYLMW RNWQHKNMKS MNFDNPVYLK TTEEDLSIDI 
GRHSASVGHT YPAISVVSTD DDLA

Genular Protein ID: 2953166252

Symbol: Q5VVF5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5VVF5

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 5 ExpressionAtlas 1 GO 4 Gene3D 3 HOGENOM 1 InterPro 12 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 8 PROSITE-ProRule 3 Pfam 5 PharmGKB 1 RefSeq 1 SAM 2 SMART 4 SMR 1 SUPFAM 3 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 845
  • Mass: 93383
  • Checksum: 588311D7C6B2C1FD
  • Sequence:
    • MGTSALWALW LLLALCWAPR ESGATGTGRK AKCEPSQFQC TNGRCITLLW KCDGDEDCVD 
GSDEKNCVKK TCAESDFVCN NGQCVPSRWK CDGDPDCEDG SDESPEQCHM RTCRIHEISC 
GAHSTQCIPV SWRCDGENDC DSGEDEENCG NITCSPDEFT CSSGRCISRN FVCNGQDDCS 
DGSDELDCAP PTCGAHEFQC STSSCIPISW VCDDDADCSD QSDESLEQCG RQPVIHTKCP 
ASEIQCGSGE CIHKKWRCDG DPDCKDGSDE VNCPSRTCRP DQFECEDGSC IHGSRQCNGI 
RDCVDGSDEV NCKNVNQCLG PGKFKCRSGE CIDISKVCNQ EQDCRDWSDE PLKECHINEC 
LVNNGGCSHI CKDLVIGYEC DCAAGFELID RKTCGDIDEC QNPGICSQIC INLKGGYKCE 
CSRGYQMDLA TGVCKAVGKE PSLIFTNRRD IRKIGLERKE YIQLVEQLRN TVALDADIAA 
QKLFWADLSQ KAIFSASIDD KVGRHVKMID NVYNPAAIAV DWVYKTIYWT DAASKTISVA 
TLDGTKRKFL FNSDLREPAS IAVDPLSGFV YWSDWGEPAK IEKAGMNGFD RRPLVTADIQ 
WPNGITLDLI KSRLYWLDSK LHMLSSVDLN GQDRRIVLKS LEFLAHPLAL TIFEDRVYWI 
DGENEAVYGA NKFTGSELAT LVNNLNDAQD IIVYHELVQP SGKNWCEEDM ENGGCEYLCL 
PAPQINDHSP KYTCSCPSGY NVEENGRDCQ RINVTTAVSE VSVPPKGTSA AWAILPLLLL 
VMAAVGGYLM WRNWQHKNMK SMNFDNPVYL KTTEEDLSID IGRHSASVGH TYPAISVVST 
DDDLA

Genular Protein ID: 3407662142

Symbol: A0A7P0T897_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A7P0T897

Database IDs:

ARBA 12 AlphaFoldDB 1 Bgee 1 CDD 2 CTD 1 DisGeNET 1 EMBL 1 Ensembl 2 GO 5 Gene3D 3 GeneTree 1 HGNC 1 InterPro 12 NCBI Taxonomy 1 PANTHER 2 PRINTS 1 PROSITE 8 PROSITE-ProRule 3 PeptideAtlas 2 Pfam 4 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 4 SMR 1 SUPFAM 3

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 832
  • Mass: 91591
  • Checksum: DECBB69556BFEB5B
  • Sequence:
    • MGTSALWALW LLLALCWAPR ESGATGTGRK AKCEPSQFQC TNGRCITLLW KCDGDEDCVD 
GSDEKNCVKK TCAESDFVCN NGQCVPSRWK CDGDPDCEDG SDESPEQCRN ITCSPDEFTC 
SSGRCISRNF VCNGQDDCSD GSDELDCAPP TCGAHEFQCS TSSCIPISWV CDDDADCSDQ 
SDESLEQCGR QPVIHTKCPA SEIQCGSGEC IHKKWRCDGD PDCKDGSDEV NCPSRTCRPD 
QFECEDGSCI HGSRQCNGIR DCVDGSDEVN CKNVNQCLGP GKFKCRSGEC IDISKVCNQE 
QDCRDWSDEP LKECHINECL VNNGGCSHIC KDLVIGYECD CAAGFELIDR KTCGDIDECQ 
NPGICSQICI NLKGGYKCEC SRGYQMDLAT GVCKAVGKEP SLIFTNRRDI RKIGLERKEY 
IQLVEQLRNT VALDADIAAQ KLFWADLSQK AIFSASIDDK VGRHVKMIDN VYNPAAIAVD 
WVYKTIYWTD AASKTISVAT LDGTKRKFLF NSDLREPASI AVDPLSGFVY WSDWGEPAKI 
EKAGMNGFDR RPLVTADIQW PNGITLDLIK SRLYWLDSKL HMLSSVDLNG QDRRIVLKSL 
EFLAHPLALT IFEDRVYWID GENEAVYGAN KFTGSELATL VNNLNDAQDI IVYHELVQPS 
GKNWCEEDME NGGCEYLCLP APQINDHSPK YTCSCPSGYN VEENGRDCQS TATTVTYSET 
KDTNTTEISA TSGLVPGGIN VTTAVSEVSV PPKGTSAAWA ILPLLLLVMA AVGGYLMWRN 
WQHKNMKSMN FDNPVYLKTT EEDLSIDIGR HSASVGHTYP AISVVSTDDD LA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.