Details for: WNT2B
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 110.0002
Cell Significance Index: -17.1100 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 67.6935
Cell Significance Index: -17.1700 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 36.9184
Cell Significance Index: -17.4300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 14.0110
Cell Significance Index: -17.2800 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 6.6783
Cell Significance Index: 32.4800 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 6.0770
Cell Significance Index: -13.3000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 4.4221
Cell Significance Index: -17.4500 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 4.2879
Cell Significance Index: -13.1700 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 2.1706
Cell Significance Index: 29.6200 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.9247
Cell Significance Index: 13.3000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.7193
Cell Significance Index: 71.1600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6807
Cell Significance Index: 614.6200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.6797
Cell Significance Index: 42.8400 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.6045
Cell Significance Index: 9.5900 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.5687
Cell Significance Index: 11.1000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.5403
Cell Significance Index: 15.1000 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 0.5136
Cell Significance Index: 7.7400 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.5045
Cell Significance Index: 10.5600 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3893
Cell Significance Index: 63.3200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.3668
Cell Significance Index: 39.9000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3666
Cell Significance Index: 69.7600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.2807
Cell Significance Index: 16.8500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.2759
Cell Significance Index: 55.3400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.2547
Cell Significance Index: 50.5400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.2352
Cell Significance Index: 5.8800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1969
Cell Significance Index: 13.6200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1900
Cell Significance Index: 8.6100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1761
Cell Significance Index: 5.0800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1679
Cell Significance Index: 60.2200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.1505
Cell Significance Index: 5.7000 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1476
Cell Significance Index: 102.0700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.1331
Cell Significance Index: 16.3600 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.1212
Cell Significance Index: 5.3600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1115
Cell Significance Index: 20.1000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.1114
Cell Significance Index: 6.8500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0844
Cell Significance Index: 6.4800 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0792
Cell Significance Index: 149.0400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0771
Cell Significance Index: 8.9900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0462
Cell Significance Index: 1.0000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0421
Cell Significance Index: 1.4800 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0344
Cell Significance Index: 18.7700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0339
Cell Significance Index: 4.6500 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: 0.0331
Cell Significance Index: 0.2000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0329
Cell Significance Index: 50.6700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0259
Cell Significance Index: 16.4400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0215
Cell Significance Index: 9.5200 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0199
Cell Significance Index: 36.7200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0120
Cell Significance Index: 16.3400 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.0101
Cell Significance Index: 0.1200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0030
Cell Significance Index: -0.1700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0099
Cell Significance Index: -0.1700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0107
Cell Significance Index: -0.2900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0173
Cell Significance Index: -1.1600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0176
Cell Significance Index: -13.0500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0179
Cell Significance Index: -8.1400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0215
Cell Significance Index: -15.7400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0232
Cell Significance Index: -17.5400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0276
Cell Significance Index: -7.9500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0293
Cell Significance Index: -16.5500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0304
Cell Significance Index: -18.9600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0525
Cell Significance Index: -7.6300 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0612
Cell Significance Index: -1.3400 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0638
Cell Significance Index: -8.1800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0661
Cell Significance Index: -11.2900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0725
Cell Significance Index: -8.3100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0837
Cell Significance Index: -1.4000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0839
Cell Significance Index: -17.6800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1212
Cell Significance Index: -15.6600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1316
Cell Significance Index: -8.0700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1335
Cell Significance Index: -15.7400 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1349
Cell Significance Index: -13.7900 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1354
Cell Significance Index: -3.5600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1363
Cell Significance Index: -14.1900 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: -0.1422
Cell Significance Index: -1.2300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1436
Cell Significance Index: -7.4600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1479
Cell Significance Index: -6.9000 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1660
Cell Significance Index: -3.5400 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1936
Cell Significance Index: -13.6900 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.1976
Cell Significance Index: -4.7400 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2084
Cell Significance Index: -10.5300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2225
Cell Significance Index: -10.4600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2229
Cell Significance Index: -16.6100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.2243
Cell Significance Index: -14.4700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2251
Cell Significance Index: -11.8200 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.2276
Cell Significance Index: -3.2600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.2529
Cell Significance Index: -8.1000 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.2587
Cell Significance Index: -3.7200 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.2680
Cell Significance Index: -5.5600 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.2958
Cell Significance Index: -4.8800 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.2976
Cell Significance Index: -7.6500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.3012
Cell Significance Index: -15.6900 - Cell Name: peg cell (CL4033014)
Fold Change: -0.3017
Cell Significance Index: -6.9700 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.3603
Cell Significance Index: -5.3200 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.3790
Cell Significance Index: -12.4100 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.3842
Cell Significance Index: -10.9700 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.3939
Cell Significance Index: -13.8000 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: -0.4045
Cell Significance Index: -4.1900 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.4091
Cell Significance Index: -13.0300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.4101
Cell Significance Index: -14.2500 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.4122
Cell Significance Index: -15.1300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1186558414
Symbol: WNT2B_HUMAN
Name: Protein Wnt-2b
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8761309
Title: Cloning, expression and chromosomal localization of Wnt-13, a novel member of the Wnt gene family.
PubMed ID: 8761309
PubMed ID: 10944466
Title: Alternative splicing of the WNT-2B/WNT-13 gene.
PubMed ID: 10944466
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9441749
Title: Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21.
PubMed ID: 9441749
PubMed ID: 18780401
Title: Identification of N-linked glycoproteins in human milk by hydrophilic interaction liquid chromatography and mass spectrometry.
PubMed ID: 18780401
PubMed ID: 26902720
Title: Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/alpha-albumin.
PubMed ID: 26902720
DOI: 10.7554/elife.11621
PubMed ID: 29909964
Title: Neonatal-Onset Chronic Diarrhea Caused by Homozygous Nonsense WNT2B Mutations.
PubMed ID: 29909964
Sequence Information:
- Length: 391
- Mass: 43770
- Checksum: BD7BB7F795FB33B1
- Sequence:
MLRPGGAEEA AQLPLRRASA PVPVPSPAAP DGSRASARLG LACLLLLLLL TLPARVDTSW WYIGALGARV ICDNIPGLVS RQRQLCQRYP DIMRSVGEGA REWIRECQHQ FRHHRWNCTT LDRDHTVFGR VMLRSSREAA FVYAISSAGV VHAITRACSQ GELSVCSCDP YTRGRHHDQR GDFDWGGCSD NIHYGVRFAK AFVDAKEKRL KDARALMNLH NNRCGRTAVR RFLKLECKCH GVSGSCTLRT CWRALSDFRR TGDYLRRRYD GAVQVMATQD GANFTAARQG YRRATRTDLV YFDNSPDYCV LDKAAGSLGT AGRVCSKTSK GTDGCEIMCC GRGYDTTRVT RVTQCECKFH WCCAVRCKEC RNTVDVHTCK APKKAEWLDQ T
Genular Protein ID: 2520410377
Symbol: Q5TEH8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
Sequence Information:
- Length: 299
- Mass: 33945
- Checksum: D6540DC48F592C09
- Sequence:
MRSVGEGARE WIRECQHQFR HHRWNCTTLD RDHTVFGRVM LRSSREAAFV YAISSAGVVH AITRACSQGE LSVCSCDPYT RGRHHDQRGD FDWGGCSDNI HYGVRFAKAF VDAKEKRLKD ARALMNLHNN RCGRTAVRRF LKLECKCHGV SGSCTLRTCW RALSDFRRTG DYLRRRYDGA VQVMATQDGA NFTAARQGYR RATRTDLVYF DNSPDYCVLD KAAGSLGTAG RVCSKTSKGT DGCEIMCCGR GYDTTRVTRV TQCECKFHWC CAVRCKECRN TVDVHTCKAP KKAEWLDQT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.