Details for: ZNF33A

Gene ID: 7581

Symbol: ZNF33A

Ensembl ID: ENSG00000189180

Description: zinc finger protein 33A

Associated with

  • Epigenetic regulation of gene expression
    (R-HSA-212165)
  • Gene expression (transcription)
    (R-HSA-74160)
  • Generic transcription pathway
    (R-HSA-212436)
  • Regulation of endogenous retroelements
    (R-HSA-9842860)
  • Regulation of endogenous retroelements by krab-zfp proteins
    (R-HSA-9843940)
  • Rna polymerase ii transcription
    (R-HSA-73857)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Metal ion binding
    (GO:0046872)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 266.3534
    Cell Significance Index: -41.4300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 154.5477
    Cell Significance Index: -39.2000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 88.3431
    Cell Significance Index: -35.8900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 79.1916
    Cell Significance Index: -40.7400
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 63.0009
    Cell Significance Index: -42.2800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 37.7484
    Cell Significance Index: -36.0400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 35.1270
    Cell Significance Index: -43.3100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 14.4203
    Cell Significance Index: -38.6300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 13.6417
    Cell Significance Index: -41.9000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 11.1605
    Cell Significance Index: -44.0400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.2297
    Cell Significance Index: -20.2000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.0640
    Cell Significance Index: 28.1600
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 2.0267
    Cell Significance Index: 17.9900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.8736
    Cell Significance Index: 371.8200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.7611
    Cell Significance Index: 47.0300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.6966
    Cell Significance Index: 101.8600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.5282
    Cell Significance Index: 166.2300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.4532
    Cell Significance Index: 291.5200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.3842
    Cell Significance Index: 77.6800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.1653
    Cell Significance Index: 210.0700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.1400
    Cell Significance Index: 408.8900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.0551
    Cell Significance Index: 129.7300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.9854
    Cell Significance Index: 25.3300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.9654
    Cell Significance Index: 26.9800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.9287
    Cell Significance Index: 71.2700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.9126
    Cell Significance Index: 15.6400
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.8312
    Cell Significance Index: 10.3100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.8169
    Cell Significance Index: 50.2100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.7069
    Cell Significance Index: 32.9600
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.6856
    Cell Significance Index: 15.8400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5968
    Cell Significance Index: 325.9100
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.5904
    Cell Significance Index: 14.1600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5336
    Cell Significance Index: 11.5600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.4785
    Cell Significance Index: 13.0300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.4476
    Cell Significance Index: 9.8000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.4426
    Cell Significance Index: 27.9000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4373
    Cell Significance Index: 30.2400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4101
    Cell Significance Index: 11.8200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.4045
    Cell Significance Index: 26.1000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.3804
    Cell Significance Index: 16.8300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.3628
    Cell Significance Index: 7.0800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3494
    Cell Significance Index: 18.1500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.2889
    Cell Significance Index: 10.9400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2802
    Cell Significance Index: 123.9100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2785
    Cell Significance Index: 38.2500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2304
    Cell Significance Index: 10.8300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.2058
    Cell Significance Index: 13.8400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1856
    Cell Significance Index: 35.3200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1757
    Cell Significance Index: 111.6100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1737
    Cell Significance Index: 4.6600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1721
    Cell Significance Index: 29.3800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1693
    Cell Significance Index: 16.7500
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 0.1491
    Cell Significance Index: 0.9200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1418
    Cell Significance Index: 267.0200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1398
    Cell Significance Index: 63.4500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1326
    Cell Significance Index: 244.6400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1297
    Cell Significance Index: 199.7300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.1258
    Cell Significance Index: 1.5000
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.1036
    Cell Significance Index: 1.7500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0851
    Cell Significance Index: 10.0400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0786
    Cell Significance Index: 12.7900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0676
    Cell Significance Index: 3.0700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0631
    Cell Significance Index: 57.0200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0605
    Cell Significance Index: 82.3200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0132
    Cell Significance Index: 9.6500
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 0.0050
    Cell Significance Index: 0.0500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.0005
    Cell Significance Index: 0.0100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0111
    Cell Significance Index: -6.9500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0153
    Cell Significance Index: -11.3300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0153
    Cell Significance Index: -1.0800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0282
    Cell Significance Index: -21.3800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0291
    Cell Significance Index: -3.7300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0386
    Cell Significance Index: -0.5700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0521
    Cell Significance Index: -29.3700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0731
    Cell Significance Index: -9.4500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0854
    Cell Significance Index: -8.7300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1021
    Cell Significance Index: -21.5100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1247
    Cell Significance Index: -18.1200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1281
    Cell Significance Index: -36.8700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1379
    Cell Significance Index: -7.2400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1719
    Cell Significance Index: -3.6600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2057
    Cell Significance Index: -23.5700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2061
    Cell Significance Index: -24.0200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2260
    Cell Significance Index: -16.8400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2307
    Cell Significance Index: -26.3300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2662
    Cell Significance Index: -27.7200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2786
    Cell Significance Index: -5.7800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3069
    Cell Significance Index: -9.8300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3319
    Cell Significance Index: -5.5600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.3621
    Cell Significance Index: -12.7300
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.3672
    Cell Significance Index: -2.8300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3823
    Cell Significance Index: -10.9100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3951
    Cell Significance Index: -13.7300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4148
    Cell Significance Index: -32.8500
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.4182
    Cell Significance Index: -3.4100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.4250
    Cell Significance Index: -9.0200
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.4519
    Cell Significance Index: -6.6700
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.4619
    Cell Significance Index: -11.2700
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.4812
    Cell Significance Index: -6.0000
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.5035
    Cell Significance Index: -7.2300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ZN33A is a member of the zinc finger protein family, characterized by its unique zinc finger domain, which allows it to bind to specific DNA sequences. This domain enables ZN33A to interact with RNA polymerase II, a crucial enzyme responsible for transcribing genes into mRNA. ZN33A's ability to bind to RNA polymerase II and facilitate transcriptional activation has been confirmed through various biochemical and molecular biology studies. **Pathways and Functions:** ZN33A's primary function is to regulate gene expression by interacting with RNA polymerase II and enhancing its transcriptional activity. This process involves the binding of ZN33A to specific DNA sequences, which are often located in the promoter regions of target genes. By recruiting RNA polymerase II to these sites, ZN33A promotes the transcription of genes involved in various cellular processes, including cell growth, differentiation, and survival. ZN33A's involvement in transcriptional regulation is mediated through several key pathways, including: 1. **DNA-binding transcription factor activity**: ZN33A's ability to bind to DNA sequences enables it to regulate gene expression by modulating the activity of transcription factors. 2. **Positive regulation of transcription by RNA polymerase II**: ZN33A's interaction with RNA polymerase II enhances its transcriptional activity, leading to the increased expression of target genes. 3. **Regulation of DNA-templated transcription**: ZN33A's role in regulating transcription is critical for maintaining the integrity of the genome and ensuring the proper expression of genes. **Clinical Significance:** ZN33A's expression in various tissues and its involvement in transcriptional regulation have significant implications for human health. Aberrant expression of ZN33A has been implicated in several diseases, including: 1. **Cancer**: ZN33A's role in regulating gene expression has been linked to cancer development and progression, particularly in prostate cancer. 2. **Neurological disorders**: ZN33A's expression in neuronal cells has been associated with neurodegenerative diseases, such as Alzheimer's and Parkinson's. 3. **Eye diseases**: ZN33A's involvement in regulating gene expression in the eye has been linked to the development of age-related macular degeneration. In conclusion, ZN33A is a critical transcriptional regulator that plays a pivotal role in regulating gene expression and transcriptional processes in various cell types. Its clinical significance and potential implications for human health highlight the need for further research into the functions and dysregulation of ZN33A in disease states.

Genular Protein ID: 784717551

Symbol: ZN33A_HUMAN

Name: Zinc finger protein 33A

UniProtKB Accession Codes:

Q06730 A8K9X9 B4E0M8 F6TH33 F8WAJ5 P17013 Q5VZ86

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 EMBL 9 Ensembl 3 ExpressionAtlas 1 GO 7 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 2 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 2 RefSeq 13 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 12535642

Title: A novel zinc finger protein, ZZaPK, interacts with ZAK and stimulates the ZAK-expressing cells re-entering the cell cycle.

PubMed ID: 12535642

DOI: 10.1016/s0006-291x(02)02980-7

PubMed ID: 7584044

Title: Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 7584044

DOI: 10.1093/dnares/1.5.223

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 8464732

Title: Duplicated KOX zinc finger gene clusters flank the centromere of human chromosome 10: evidence for a pericentric inversion during primate evolution.

PubMed ID: 8464732

DOI: 10.1093/nar/21.6.1409

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 810
  • Mass: 94384
  • Checksum: 96AD969EF541B73E
  • Sequence:
    • MNKVEQKSQE SVSFKDVTVG FTQEEWQHLD PSQRALYRDV MLENYSNLVS VGYCVHKPEV 
IFRLQQGEEP WKQEEEFPSQ SFPVWTADHL KERSQENQSK HLWEVVFINN EMLTKEQGDV 
IGIPFNVDVS SFPSRKMFCQ CDSCGMSFNT VSELVISKIN YLGKKSDEFN ACGKLLLNIK 
HDETHTQEKN EVLKNRNTLS HHEETLQHEK IQTLEHNFEY SICQETLLEK AVFNTQKREN 
AEENNCDYNE FGRTLCDSSS LLFHQISPSR DNHYEFSDCE KFLCVKSTLS KPHGVSMKHY 
DCGESGNNFR RKLCLSHLQK GDKGEKHFEC NECGKAFWEK SHLTRHQRVH TGQKPFQCNE 
CEKAFWDKSN LTKHQRSHTG EKPFECNECG KAFSHKSALT LHQRTHTGEK PYQCNACGKT 
FCQKSDLTKH QRTHTGLKPY ECYECGKSFR VTSHLKVHQR THTGEKPFEC LECGKSFSEK 
SNLTQHQRIH IGDKSYECNA CGKTFYHKSL LTRHQIIHTG WKPYECYECG KTFCLKSDLT 
VHQRTHTGQK PFACPECGKF FSHKSTLSQH YRTHTGEKPY ECHECGKIFY NKSYLTKHNR 
THTGEKPYEC NECGKAFYQK SQLTQHQRIH IGEKPYKCNE CGKAFCHKSA LIVHQRTHTQ 
EKPYKCNECG KSFCVKSGLI FHERKHTGEK PYECNECGKF FRHKSSLTVH HRAHTGEKSC 
QCNECGKIFY RKSELAQHQR SHTGEKPYEC NTCRKTFSQK SNLIVHQRRH IGENLMNEMD 
IRNFQPQVSL HNASEYSHCG ESPDDILNVQ

Genular Protein ID: 3945115306

Symbol: A0A0A0MRS1_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MRS1

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 2 MassIVE 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 7 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.O114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 699
  • Mass: 81158
  • Checksum: 74198A9327BC2930
  • Sequence:
    • MLTKEQGDVI GIPFNVDVSS FPSRKMFCQC DSCGMSFNTV SELVISKINY LGKKSDEFNA 
CGKLLLNIKH DETHTQEKNE VLKNRNTLSH HEETLQHEKI QTLEHNFEYS ICQETLLEKA 
VFNTQKRENA EENNCDYNEF GRTLCDSSSL LFHQISPSRD NHYEFSDCEK FLCVKSTLSK 
PHGVSMKHYD CGESGNNFRR KLCLSHLQKG DKGEKHFECN ECGKAFWEKS HLTRHQRVHT 
GQKPFQCNEC EKAFWDKSNL TKHQRSHTGE KPFECNECGK AFSHKSALTL HQRTHTGEKP 
YQCNACGKTF CQKSDLTKHQ RTHTGLKPYE CYECGKSFRV TSHLKVHQRT HTGEKPFECL 
ECGKSFSEKS NLTQHQRIHI GDKSYECNAC GKTFYHKSLL TRHQIIHTGW KPYECYECGK 
TFCLKSDLTV HQRTHTGQKP FACPECGKFF SHKSTLSQHY RTHTGEKPYE CHECGKIFYN 
KSYLTKHNRT HTGEKPYECN ECGKAFYQKS QLTQHQRIHI GEKPYKCNEC GKAFCHKSAL 
IVHQRTHTQE KPYKCNECGK SFCVKSGLIF HERKHTGEKP YECNECGKFF RHKSSLTVHH 
RAHTGEKSCQ CNECGKIFYR KSELAQHQRS HTGEKPYECN TCRKTFSQKS NLIVHQRRHI 
GENLMNEMDI RNFQPQVSLH NASEYSHCGE SPDDILNVQ

Genular Protein ID: 1242503801

Symbol: A0A0A0MR11_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MR11

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 2 GeneTree 1 HGNC 1 InterPro 5 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SMART 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.O114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 829
  • Mass: 96585
  • Checksum: 645254E7FFBA04DD
  • Sequence:
    • MCPRGYPEQS NWMSSPLYST EVEQKSQESV SFKDVTVGFT QEEWQHLDPS QRALYRDVML 
ENYSNLVSVG YCVHKPEVIF RLQQGEEPWK QEEEFPSQSF PEVWTADHLK ERSQENQSKH 
LWEVVFINNE MLTKEQGDVI GIPFNVDVSS FPSRKMFCQC DSCGMSFNTV SELVISKINY 
LGKKSDEFNA CGKLLLNIKH DETHTQEKNE VLKNRNTLSH HEETLQHEKI QTLEHNFEYS 
ICQETLLEKA VFNTQKRENA EENNCDYNEF GRTLCDSSSL LFHQISPSRD NHYEFSDCEK 
FLCVKSTLSK PHGVSMKHYD CGESGNNFRR KLCLSHLQKG DKGEKHFECN ECGKAFWEKS 
HLTRHQRVHT GQKPFQCNEC EKAFWDKSNL TKHQRSHTGE KPFECNECGK AFSHKSALTL 
HQRTHTGEKP YQCNACGKTF CQKSDLTKHQ RTHTGLKPYE CYECGKSFRV TSHLKVHQRT 
HTGEKPFECL ECGKSFSEKS NLTQHQRIHI GDKSYECNAC GKTFYHKSLL TRHQIIHTGW 
KPYECYECGK TFCLKSDLTV HQRTHTGQKP FACPECGKFF SHKSTLSQHY RTHTGEKPYE 
CHECGKIFYN KSYLTKHNRT HTGEKPYECN ECGKAFYQKS QLTQHQRIHI GEKPYKCNEC 
GKAFCHKSAL IVHQRTHTQE KPYKCNECGK SFCVKSGLIF HERKHTGEKP YECNECGKFF 
RHKSSLTVHH RAHTGEKSCQ CNECGKIFYR KSELAQHQRS HTGEKPYECN TCRKTFSQKS 
NLIVHQRRHI GENLMNEMDI RNFQPQVSLH NASEYSHCGE SPDDILNVQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.