Details for: ZKSCAN1

Gene ID: 7586

Symbol: ZKSCAN1

Ensembl ID: ENSG00000106261

Description: zinc finger with KRAB and SCAN domains 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 449.7084
    Cell Significance Index: -69.9500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 246.1724
    Cell Significance Index: -62.4400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 151.8038
    Cell Significance Index: -71.6700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 145.3759
    Cell Significance Index: -59.0600
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 130.6219
    Cell Significance Index: -67.1900
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 106.9264
    Cell Significance Index: -71.7500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 62.0481
    Cell Significance Index: -59.2400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 57.5122
    Cell Significance Index: -70.9100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 24.8949
    Cell Significance Index: -66.6900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 18.0687
    Cell Significance Index: -71.3000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 17.8775
    Cell Significance Index: -54.9100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 13.4653
    Cell Significance Index: -29.4700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 3.8756
    Cell Significance Index: 65.2900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 2.5089
    Cell Significance Index: 272.9000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.2230
    Cell Significance Index: 441.1700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.0793
    Cell Significance Index: 417.1100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.9777
    Cell Significance Index: 55.2700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.9321
    Cell Significance Index: 348.2900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.3188
    Cell Significance Index: 181.1100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.2963
    Cell Significance Index: 464.9600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.2774
    Cell Significance Index: 57.9000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.2602
    Cell Significance Index: 688.2000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.2250
    Cell Significance Index: 199.2400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.1790
    Cell Significance Index: 54.9700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.1418
    Cell Significance Index: 140.4000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.1316
    Cell Significance Index: 32.6100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.0327
    Cell Significance Index: 57.9500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.8118
    Cell Significance Index: 49.9000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.7104
    Cell Significance Index: 49.1300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.5114
    Cell Significance Index: 33.0000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.5096
    Cell Significance Index: 225.2900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.4788
    Cell Significance Index: 12.7900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4453
    Cell Significance Index: 44.0500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4452
    Cell Significance Index: 84.7300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4108
    Cell Significance Index: 21.3400
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.3713
    Cell Significance Index: 5.4800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3675
    Cell Significance Index: 254.1900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.3631
    Cell Significance Index: 27.8600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3548
    Cell Significance Index: 320.4000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.3128
    Cell Significance Index: 10.8700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.2604
    Cell Significance Index: 11.5200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.2532
    Cell Significance Index: 18.8700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2365
    Cell Significance Index: 30.3200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1724
    Cell Significance Index: 4.6200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.1703
    Cell Significance Index: 6.4500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1562
    Cell Significance Index: 26.6800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1482
    Cell Significance Index: 279.0800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1368
    Cell Significance Index: 9.2000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1330
    Cell Significance Index: 6.2500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1311
    Cell Significance Index: 9.2700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0907
    Cell Significance Index: 57.6200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0592
    Cell Significance Index: 91.1100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0578
    Cell Significance Index: 106.5400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0460
    Cell Significance Index: 1.2100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0250
    Cell Significance Index: 34.0600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0201
    Cell Significance Index: 9.1100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0197
    Cell Significance Index: 1.2400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0031
    Cell Significance Index: 2.2600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0296
    Cell Significance Index: -21.9100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0323
    Cell Significance Index: -0.8800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0410
    Cell Significance Index: -25.6200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0589
    Cell Significance Index: -7.6100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0799
    Cell Significance Index: -60.4700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0939
    Cell Significance Index: -52.9500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1034
    Cell Significance Index: -2.4800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1383
    Cell Significance Index: -14.1300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1487
    Cell Significance Index: -31.3200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1537
    Cell Significance Index: -5.4000
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1853
    Cell Significance Index: -4.2800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1984
    Cell Significance Index: -3.4000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2041
    Cell Significance Index: -23.7900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2096
    Cell Significance Index: -60.3200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.2244
    Cell Significance Index: -4.3800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2301
    Cell Significance Index: -27.1300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2369
    Cell Significance Index: -3.9700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2399
    Cell Significance Index: -34.8700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2957
    Cell Significance Index: -9.4700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3027
    Cell Significance Index: -7.7800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3034
    Cell Significance Index: -15.9300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3320
    Cell Significance Index: -38.0400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3839
    Cell Significance Index: -43.8200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5793
    Cell Significance Index: -60.3200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.6136
    Cell Significance Index: -31.9600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.6897
    Cell Significance Index: -9.4100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.7217
    Cell Significance Index: -57.1600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.8595
    Cell Significance Index: -17.9900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.8792
    Cell Significance Index: -25.0900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.9092
    Cell Significance Index: -55.7400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.9282
    Cell Significance Index: -20.1100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -1.1087
    Cell Significance Index: -10.2100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -1.1379
    Cell Significance Index: -29.0700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -1.1961
    Cell Significance Index: -26.1900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.2708
    Cell Significance Index: -37.4300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.2916
    Cell Significance Index: -34.5500
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -1.3647
    Cell Significance Index: -17.5800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.3743
    Cell Significance Index: -43.7700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -1.3849
    Cell Significance Index: -39.7000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.4035
    Cell Significance Index: -45.9500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.4272
    Cell Significance Index: -30.2900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -1.4440
    Cell Significance Index: -42.4100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ZKSCAN1 is a transcription factor that belongs to the zinc finger protein family. Its unique structure, comprising a KRAB and SCAN domain, enables it to interact with specific DNA sequences and regulate gene expression. The KRAB domain is responsible for binding to the histone methyltransferase Suv39h1, leading to the silencing of target genes. The SCAN domain, on the other hand, facilitates the recruitment of the transcriptional machinery to specific DNA sequences. These characteristics allow ZKSCAN1 to fine-tune gene expression in endodermal tissues, ensuring proper development and function. **Pathways and Functions:** ZKSCAN1 regulates gene expression through its interaction with the RNA polymerase II (Pol II) transcription machinery. As a member of the generic transcription pathway, ZKSCAN1 plays a crucial role in the regulation of transcription by Pol II, particularly in the context of cis-regulatory regions. Its ability to bind to specific DNA sequences and recruit the transcriptional machinery enables it to modulate gene expression in endodermal tissues. Furthermore, ZKSCAN1's involvement in metal ion binding and protein-protein interactions highlights its versatility and ability to interact with various cellular components. **Clinical Significance:** Dysregulation of ZKSCAN1 has been implicated in various diseases, including cancer and developmental disorders. For instance, aberrant expression of ZKSCAN1 has been observed in certain types of cancer, such as lung and prostate cancer, where it may contribute to tumorigenesis. Additionally, mutations in the ZKSCAN1 gene have been linked to developmental disorders, highlighting the gene's importance in endodermal development and patterning. Understanding the functions and clinical significance of ZKSCAN1 can provide valuable insights into the development of novel therapeutic strategies for these diseases. In conclusion, ZKSCAN1 is a transcriptional regulator that plays a critical role in the development and maintenance of endodermal lineages. Its unique structure and interactions with the transcriptional machinery enable it to regulate gene expression in a specific and context-dependent manner. Further research on ZKSCAN1 can provide valuable insights into the underlying mechanisms of endodermal development and disease, ultimately leading to the development of novel therapeutic strategies.

Genular Protein ID: 3450312469

Symbol: ZKSC1_HUMAN

Name: Zinc finger protein with KRAB and SCAN domains 1

UniProtKB Accession Codes:

P17029 A4D294 P52745 Q2M1U1 Q8TBW5 Q8TEK7

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 9 Ensembl 1 ExpressionAtlas 1 GO 5 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 NIAGADS 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 12693554

Title: Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones.

PubMed ID: 12693554

DOI: 10.1093/dnares/10.1.49

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7557990

Title: Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

PubMed ID: 7557990

DOI: 10.1006/geno.1995.1040

PubMed ID: 2288909

Title: Multiple genes encoding zinc finger domains are expressed in human T cells.

PubMed ID: 2288909

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 563
  • Mass: 63630
  • Checksum: 9960C9E320554352
  • Sequence:
    • MMTAESREAT GLSPQAAQEK DGIVIVKVEE EDEEDHMWGQ DSTLQDTPPP DPEIFRQRFR 
RFCYQNTFGP REALSRLKEL CHQWLRPEIN TKEQILELLV LEQFLSILPK ELQVWLQEYR 
PDSGEEAVTL LEDLELDLSG QQVPGQVHGP EMLARGMVPL DPVQESSSFD LHHEATQSHF 
KHSSRKPRLL QSRALPAAHI PAPPHEGSPR DQAMASALFT ADSQAMVKIE DMAVSLILEE 
WGCQNLARRN LSRDNRQENY GSAFPQGGEN RNENEESTSK AETSEDSASR GETTGRSQKE 
FGEKRDQEGK TGERQQKNPE EKTRKEKRDS GPAIGKDKKT ITGERGPREK GKGLGRSFSL 
SSNFTTPEEV PTGTKSHRCD ECGKCFTRSS SLIRHKIIHT GEKPYECSEC GKAFSLNSNL 
VLHQRIHTGE KPHECNECGK AFSHSSNLIL HQRIHSGEKP YECNECGKAF SQSSDLTKHQ 
RIHTGEKPYE CSECGKAFNR NSYLILHRRI HTREKPYKCT KCGKAFTRSS TLTLHHRIHA 
RERASEYSPA SLDAFGAFLK SCV

Genular Protein ID: 3147764743

Symbol: B3KRF7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KRF7

Database IDs:

ARBA 5 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 2 GO 3 Gene3D 2 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 4 NCBI Taxonomy 1 NIAGADS 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 2 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 350
  • Mass: 39324
  • Checksum: 571E460A2C8FC961
  • Sequence:
    • MASALFTADS QAMVKIEDMA VSLILEEWGC QNLARRNLSR DNRQENYGSA FPQGGENRNE 
NEESTSKAET SEDSASRGET TGRSQKEFGE KRDQEGKTGE RQQKNPEEKT RKEKRDSGPA 
IGKDKKTITG ERGPREKGKG LGRSFSLSSN FTTPEEVPTG TKSHRCDECG KCFTRSSSLI 
RHKIIHTGEK PYECSECGKA FSLNSNLVLH QRIHTGEKPH ECNECGKAFS HSSNLILHQR 
IHSGEKPYEC NECGKAFSQS SDLTKHQRIH TGEKPYECSE CGKAFNRNSY LILHRRIHTR 
EKPYKCTKCG KAFTRSSTLT LHHRIHARER ASEYSPASLD AFGAFLKSCV

Genular Protein ID: 3308881374

Symbol: B3KNP9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KNP9

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 3 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 7 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 1 SMART 3 SUPFAM 3

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 527
  • Mass: 59587
  • Checksum: CECD5F7B55500EE9
  • Sequence:
    • MWGQDSTLQV TPPPDPEIFR QRFRRFCYQN TFGPREALSR LKELCHQWLR PEINTKEQIL 
ELLVLEQFLS ILPKELQVWL QEYRPDSGEE AVTLLEDLEL DLSGQQVPGQ VHGPEMLARG 
MVPLDPVQES SSFDLHHEAT QSHFKHSSRK PRLLQSRALP AAHIPAPPHE GSPRDQAMAS 
ALFTADSQAM VKIEDMAVSL ILEEWGCQNL ARRNLSRDNR QENYGSAFPQ GGENRNENEE 
STSKAETSED SASRGETTGR SQKEFGEKRD QEGKTGERQQ KNPEEKTRKE KRDSGPAIGK 
DKKTITGERG PREKGKGLGR SFSLSSNFTT PEEVPTGTKS HRCDECGKCF TRSSSLIRHK 
IIHTGEKPYE CSECGKAFSL NSNLVLHQRI HTGGKPHECN ECGKAFSHSS NLILHQRIHS 
GEKPYECNEC GKAFSQSSDL TKHQRIHTGE KPYECSECGK AFNRNSYLIL HRRIHTREKP 
YKCTKCGKAF TRSSTLTLHH RIHARERASE YSPASLDAFG AFLKSCV

Genular Protein ID: 2587070705

Symbol: E9PC66_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PC66

Database IDs:

ARBA 7 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 3 GO 4 Gene3D 3 GeneTree 1 HGNC 1 HOGENOM 1 IntAct 1 InterPro 6 NCBI Taxonomy 1 NIAGADS 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 7 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 2 SAM 1 SMART 3 SUPFAM 3 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 527
  • Mass: 59675
  • Checksum: CECD5F79DF559846
  • Sequence:
    • MWGQDSTLQD TPPPDPEIFR QRFRRFCYQN TFGPREALSR LKELCHQWLR PEINTKEQIL 
ELLVLEQFLS ILPKELQVWL QEYRPDSGEE AVTLLEDLEL DLSGQQVPGQ VHGPEMLARG 
MVPLDPVQES SSFDLHHEAT QSHFKHSSRK PRLLQSRALP AAHIPAPPHE GSPRDQAMAS 
ALFTADSQAM VKIEDMAVSL ILEEWGCQNL ARRNLSRDNR QENYGSAFPQ GGENRNENEE 
STSKAETSED SASRGETTGR SQKEFGEKRD QEGKTGERQQ KNPEEKTRKE KRDSGPAIGK 
DKKTITGERG PREKGKGLGR SFSLSSNFTT PEEVPTGTKS HRCDECGKCF TRSSSLIRHK 
IIHTGEKPYE CSECGKAFSL NSNLVLHQRI HTGEKPHECN ECGKAFSHSS NLILHQRIHS 
GEKPYECNEC GKAFSQSSDL TKHQRIHTGE KPYECSECGK AFNRNSYLIL HRRIHTREKP 
YKCTKCGKAF TRSSTLTLHH RIHARERASE YSPASLDAFG AFLKSCV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.