Details for: PXDN

Gene ID: 7837

Symbol: PXDN

Ensembl ID: ENSG00000130508

Description: peroxidasin

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 196.9845
    Cell Significance Index: -30.6400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 118.7494
    Cell Significance Index: -30.1200
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 62.1025
    Cell Significance Index: -29.3200
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 27.4629
    Cell Significance Index: -26.2200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 24.8833
    Cell Significance Index: -30.6800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 7.7749
    Cell Significance Index: -30.6800
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 3.1148
    Cell Significance Index: 39.8900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.9722
    Cell Significance Index: 110.6700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 1.9538
    Cell Significance Index: 48.8400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.8279
    Cell Significance Index: 38.2600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.7999
    Cell Significance Index: 39.0000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.2584
    Cell Significance Index: 24.5600
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 1.2105
    Cell Significance Index: 13.1600
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.0707
    Cell Significance Index: 15.4000
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 1.0594
    Cell Significance Index: 11.0600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.9907
    Cell Significance Index: 541.0500
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 0.9601
    Cell Significance Index: 12.0900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.9243
    Cell Significance Index: 32.1200
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.9189
    Cell Significance Index: 5.6900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.8190
    Cell Significance Index: 112.4700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.8011
    Cell Significance Index: 49.2400
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.6538
    Cell Significance Index: 5.2200
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 0.6411
    Cell Significance Index: 3.7900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.5585
    Cell Significance Index: 354.7000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.5361
    Cell Significance Index: 6.0900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.5305
    Cell Significance Index: 100.9600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.5259
    Cell Significance Index: 15.4900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.4414
    Cell Significance Index: 28.4800
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.3112
    Cell Significance Index: 1.8800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3094
    Cell Significance Index: 62.0700
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.3036
    Cell Significance Index: 4.3600
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.2550
    Cell Significance Index: 1.1100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2302
    Cell Significance Index: 22.7700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.1901
    Cell Significance Index: 5.4500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1872
    Cell Significance Index: 169.0500
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 0.1821
    Cell Significance Index: 1.1400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1681
    Cell Significance Index: 316.5500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1343
    Cell Significance Index: 21.8500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1065
    Cell Significance Index: 144.7800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0863
    Cell Significance Index: 2.2700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0863
    Cell Significance Index: 4.0300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.0846
    Cell Significance Index: 2.0300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0730
    Cell Significance Index: 7.9400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0635
    Cell Significance Index: 97.8100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0565
    Cell Significance Index: 20.2600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0562
    Cell Significance Index: 0.9400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.0474
    Cell Significance Index: 5.4100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0296
    Cell Significance Index: 1.7800
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.0265
    Cell Significance Index: 0.4100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0264
    Cell Significance Index: 11.6700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0181
    Cell Significance Index: 0.8500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0105
    Cell Significance Index: -0.3700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0158
    Cell Significance Index: -2.3000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0167
    Cell Significance Index: -12.3600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0209
    Cell Significance Index: -38.5600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0228
    Cell Significance Index: -10.3700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0253
    Cell Significance Index: -15.7700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0281
    Cell Significance Index: -0.8100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0392
    Cell Significance Index: -29.6600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0399
    Cell Significance Index: -2.0800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0399
    Cell Significance Index: -29.2200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0425
    Cell Significance Index: -23.9400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0546
    Cell Significance Index: -3.3500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0741
    Cell Significance Index: -9.5800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0784
    Cell Significance Index: -1.7200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0799
    Cell Significance Index: -15.8500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0898
    Cell Significance Index: -4.0700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0922
    Cell Significance Index: -11.8200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0944
    Cell Significance Index: -27.1700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0971
    Cell Significance Index: -17.5000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1012
    Cell Significance Index: -21.3100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.1043
    Cell Significance Index: -7.2200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1051
    Cell Significance Index: -17.9500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1242
    Cell Significance Index: -14.6500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1509
    Cell Significance Index: -17.5900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1742
    Cell Significance Index: -3.7100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1879
    Cell Significance Index: -21.5300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.2080
    Cell Significance Index: -25.5800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2309
    Cell Significance Index: -17.2100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2617
    Cell Significance Index: -26.7300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2863
    Cell Significance Index: -5.9400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2874
    Cell Significance Index: -29.9200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.3531
    Cell Significance Index: -27.1000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3725
    Cell Significance Index: -29.5000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3837
    Cell Significance Index: -12.2900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3926
    Cell Significance Index: -26.4000
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.4088
    Cell Significance Index: -2.7700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.5127
    Cell Significance Index: -10.9600
  • Cell Name: chondroblast (CL0000058)
    Fold Change: -0.5775
    Cell Significance Index: -3.3900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.6155
    Cell Significance Index: -38.7900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.6167
    Cell Significance Index: -19.6400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.6276
    Cell Significance Index: -12.6000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.6296
    Cell Significance Index: -17.6000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.6641
    Cell Significance Index: -17.0700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6662
    Cell Significance Index: -34.9800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.6859
    Cell Significance Index: -35.6300
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -0.6974
    Cell Significance Index: -3.2200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.7711
    Cell Significance Index: -38.9700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.7805
    Cell Significance Index: -25.5500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.7915
    Cell Significance Index: -35.0100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Expression in various cell types**: PXDN is significantly expressed in endocardial cells, non-pigmented ciliary epithelial cells, skeletal muscle satellite stem cells, mesodermal cells, and other cell types, suggesting a broad role in maintaining cellular homeostasis. 2. **Peroxidase activity**: PXDN is a peroxidase enzyme that catalyzes the reduction of hydrogen peroxide, playing a crucial role in protecting cells against oxidative stress. 3. **Collagen formation and organization**: PXDN is involved in the assembly of collagen fibrils and multimeric structures, highlighting its importance in maintaining the integrity of the extracellular matrix. **Pathways and Functions:** 1. **Oxidative stress response**: PXDN plays a key role in mitigating oxidative stress by reducing hydrogen peroxide, thereby preventing cellular damage. 2. **Collagen formation and organization**: PXDN is essential for the assembly of collagen fibrils and multimeric structures, which is critical for maintaining the integrity of the extracellular matrix. 3. **Cell adhesion**: PXDN may contribute to cell adhesion by regulating the interaction between cells and the extracellular matrix. 4. **Immune response**: PXDN has been implicated in immune response regulation, with evidence suggesting that it acts as an interleukin-1 receptor antagonist. 5. **Metal ion binding**: PXDN can bind metal ions, which may be involved in its catalytic activity as a peroxidase enzyme. **Clinical Significance:** 1. **Oxidative stress-related diseases**: Mutations or dysregulation of PXDN may contribute to oxidative stress-related diseases, such as atherosclerosis, cancer, and neurodegenerative disorders. 2. **Collagen-related disorders**: Altered PXDN expression may lead to collagen-related disorders, such as osteogenesis imperfecta or Ehlers-Danlos syndrome. 3. **Immunological disorders**: PXDN's role in immune response regulation may be linked to immunological disorders, such as autoimmune diseases or immunodeficiency syndromes. 4. **Cancer**: PXDN's involvement in cell adhesion and immune response regulation may contribute to cancer development and progression. In conclusion, PXDN is a crucial gene involved in maintaining cellular homeostasis, regulating oxidative stress, and maintaining the integrity of the extracellular matrix. Further research is needed to fully elucidate the mechanisms of PXDN and its potential implications in disease.

Genular Protein ID: 284902058

Symbol: PXDN_HUMAN

Name: Melanoma-associated antigen MG50

UniProtKB Accession Codes:

Q92626 A8QM65 D6W4Y0 Q4KMG2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CTD 1 ChEBI 39 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 1 ExpressionAtlas 1 GO 28 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 18 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 5 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 PeroxiBase 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 Rhea 20 SABIO-RK 1 SIGNOR 1 SMART 5 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10441517

Title: Isolation of differentially expressed cDNAs from p53-dependent apoptotic cells: activation of the human homologue of the Drosophila peroxidasin gene.

PubMed ID: 10441517

DOI: 10.1006/bbrc.1999.1123

PubMed ID: 11103812

Title: A novel melanoma gene (MG50) encoding the interleukin 1 receptor antagonist and six epitopes recognized by human cytolytic T lymphocytes.

PubMed ID: 11103812

PubMed ID: 18929642

Title: Identification and characterization of VPO1, a new animal heme-containing peroxidase.

PubMed ID: 18929642

DOI: 10.1016/j.freeradbiomed.2008.09.009

PubMed ID: 9039502

Title: Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.

PubMed ID: 9039502

DOI: 10.1093/dnares/3.5.321

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 27697841

Title: Proprotein Convertase Processing Enhances Peroxidasin Activity to Reinforce Collagen IV.

PubMed ID: 27697841

DOI: 10.1074/jbc.m116.745935

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19590037

Title: Peroxidasin is secreted and incorporated into the extracellular matrix of myofibroblasts and fibrotic kidney.

PubMed ID: 19590037

DOI: 10.2353/ajpath.2009.080693

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 22842973

Title: Peroxidasin forms sulfilimine chemical bonds using hypohalous acids in tissue genesis.

PubMed ID: 22842973

DOI: 10.1038/nchembio.1038

PubMed ID: 24253521

Title: Peroxidasin-like protein: a novel peroxidase homologue in the human heart.

PubMed ID: 24253521

DOI: 10.1093/cvr/cvt256

PubMed ID: 25708780

Title: Structure-function analysis of peroxidasin provides insight into the mechanism of collagen IV crosslinking.

PubMed ID: 25708780

DOI: 10.1016/j.freeradbiomed.2015.02.015

PubMed ID: 25713063

Title: Multidomain human peroxidasin 1 is a highly glycosylated and stable homotrimeric high spin ferric peroxidase.

PubMed ID: 25713063

DOI: 10.1074/jbc.m114.632273

PubMed ID: 26178375

Title: The Ancient Immunoglobulin Domains of Peroxidasin Are Required to Form Sulfilimine Cross-links in Collagen IV.

PubMed ID: 26178375

DOI: 10.1074/jbc.m115.673996

PubMed ID: 28154175

Title: Pre-steady-state Kinetics Reveal the Substrate Specificity and Mechanism of Halide Oxidation of Truncated Human Peroxidasin 1.

PubMed ID: 28154175

DOI: 10.1074/jbc.m117.775213

PubMed ID: 29982533

Title: Human peroxidasin 1 promotes angiogenesis through ERK1/2, Akt, and FAK pathways.

PubMed ID: 29982533

DOI: 10.1093/cvr/cvy179

PubMed ID: 31953133

Title: Reaction of human peroxidasin 1 compound I and compound II with one-electron donors.

PubMed ID: 31953133

DOI: 10.1016/j.abb.2020.108267

PubMed ID: 32485152

Title: The leucine-rich repeat domain of human peroxidasin 1 promotes binding to laminin in basement membranes.

PubMed ID: 32485152

DOI: 10.1016/j.abb.2020.108443

PubMed ID: 31295557

Title: Monomeric and homotrimeric solution structures of truncated human peroxidasin 1 variants.

PubMed ID: 31295557

DOI: 10.1016/j.bbapap.2019.07.002

PubMed ID: 32543734

Title: Peroxidasin is essential for endothelial cell survival and growth signaling by sulfilimine crosslink-dependent matrix assembly.

PubMed ID: 32543734

DOI: 10.1096/fj.201902899r

PubMed ID: 32571911

Title: Peroxidasin-mediated bromine enrichment of basement membranes.

PubMed ID: 32571911

DOI: 10.1073/pnas.2007749117

PubMed ID: 34679700

Title: Characterization of the Proprotein Convertase-Mediated Processing of Peroxidasin and Peroxidasin-like Protein.

PubMed ID: 34679700

DOI: 10.3390/antiox10101565

PubMed ID: 21907015

Title: Homozygous mutations in PXDN cause congenital cataract, corneal opacity, and developmental glaucoma.

PubMed ID: 21907015

DOI: 10.1016/j.ajhg.2011.08.005

Sequence Information:

  • Length: 1479
  • Mass: 165275
  • Checksum: 7A75F533D89C6AAD
  • Sequence:
    • MAKRSRGPGR RCLLALVLFC AWGTLAVVAQ KPGAGCPSRC LCFRTTVRCM HLLLEAVPAV 
APQTSILDLR FNRIREIQPG AFRRLRNLNT LLLNNNQIKR IPSGAFEDLE NLKYLYLYKN 
EIQSIDRQAF KGLASLEQLY LHFNQIETLD PDSFQHLPKL ERLFLHNNRI THLVPGTFNH 
LESMKRLRLD SNTLHCDCEI LWLADLLKTY AESGNAQAAA ICEYPRRIQG RSVATITPEE 
LNCERPRITS EPQDADVTSG NTVYFTCRAE GNPKPEIIWL RNNNELSMKT DSRLNLLDDG 
TLMIQNTQET DQGIYQCMAK NVAGEVKTQE VTLRYFGSPA RPTFVIQPQN TEVLVGESVT 
LECSATGHPP PRISWTRGDR TPLPVDPRVN ITPSGGLYIQ NVVQGDSGEY ACSATNNIDS 
VHATAFIIVQ ALPQFTVTPQ DRVVIEGQTV DFQCEAKGNP PPVIAWTKGG SQLSVDRRHL 
VLSSGTLRIS GVALHDQGQY ECQAVNIIGS QKVVAHLTVQ PRVTPVFASI PSDTTVEVGA 
NVQLPCSSQG EPEPAITWNK DGVQVTESGK FHISPEGFLT INDVGPADAG RYECVARNTI 
GSASVSMVLS VNVPDVSRNG DPFVATSIVE AIATVDRAIN STRTHLFDSR PRSPNDLLAL 
FRYPRDPYTV EQARAGEIFE RTLQLIQEHV QHGLMVDLNG TSYHYNDLVS PQYLNLIANL 
SGCTAHRRVN NCSDMCFHQK YRTHDGTCNN LQHPMWGASL TAFERLLKSV YENGFNTPRG 
INPHRLYNGH ALPMPRLVST TLIGTETVTP DEQFTHMLMQ WGQFLDHDLD STVVALSQAR 
FSDGQHCSNV CSNDPPCFSV MIPPNDSRAR SGARCMFFVR SSPVCGSGMT SLLMNSVYPR 
EQINQLTSYI DASNVYGSTE HEARSIRDLA SHRGLLRQGI VQRSGKPLLP FATGPPTECM 
RDENESPIPC FLAGDHRANE QLGLTSMHTL WFREHNRIAT ELLKLNPHWD GDTIYYETRK 
IVGAEIQHIT YQHWLPKILG EVGMRTLGEY HGYDPGINAG IFNAFATAAF RFGHTLVNPL 
LYRLDENFQP IAQDHLPLHK AFFSPFRIVN EGGIDPLLRG LFGVAGKMRV PSQLLNTELT 
ERLFSMAHTV ALDLAAINIQ RGRDHGIPPY HDYRVYCNLS AAHTFEDLKN EIKNPEIREK 
LKRLYGSTLN IDLFPALVVE DLVPGSRLGP TLMCLLSTQF KRLRDGDRLW YENPGVFSPA 
QLTQIKQTSL ARILCDNADN ITRVQSDVFR VAEFPHGYGS CDEIPRVDLR VWQDCCEDCR 
TRGQFNAFSY HFRGRRSLEF SYQEDKPTKK TRPRKIPSVG RQGEHLSNST SAFSTRSDAS 
GTNDFREFVL EMQKTITDLR TQIKKLESRL STTECVDAGG ESHANNTKWK KDACTICECK 
DGQVTCFVEA CPPATCAVPV NIPGACCPVC LQKRAEEKP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.