Details for: BRPF1

Gene ID: 7862

Symbol: BRPF1

Ensembl ID: ENSG00000156983

Description: bromodomain and PHD finger containing 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 56.0609
    Cell Significance Index: -8.7200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 33.0779
    Cell Significance Index: -8.3900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 22.0304
    Cell Significance Index: -8.9500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 9.5209
    Cell Significance Index: -9.0900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 7.8348
    Cell Significance Index: -9.6600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.4784
    Cell Significance Index: -9.7800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 1.2474
    Cell Significance Index: -2.7300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.8234
    Cell Significance Index: 81.4500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6744
    Cell Significance Index: 40.4900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5611
    Cell Significance Index: 61.0300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5603
    Cell Significance Index: 505.9300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4435
    Cell Significance Index: 72.1300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4393
    Cell Significance Index: 19.9100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.4200
    Cell Significance Index: 11.2400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.4035
    Cell Significance Index: 47.0200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.3857
    Cell Significance Index: 20.0900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3408
    Cell Significance Index: 9.8200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.2956
    Cell Significance Index: 19.0700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2760
    Cell Significance Index: 19.0900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2557
    Cell Significance Index: 48.6700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2080
    Cell Significance Index: 13.1100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1890
    Cell Significance Index: 9.8200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1754
    Cell Significance Index: 35.1800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1650
    Cell Significance Index: 4.4900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1586
    Cell Significance Index: 3.4400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1435
    Cell Significance Index: 25.8700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1177
    Cell Significance Index: 5.4900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1098
    Cell Significance Index: 48.5500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1060
    Cell Significance Index: 21.0400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0989
    Cell Significance Index: 13.5800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.0945
    Cell Significance Index: 2.4200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0920
    Cell Significance Index: 2.3000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0900
    Cell Significance Index: 11.0700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0834
    Cell Significance Index: 2.2400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0823
    Cell Significance Index: 5.8200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0605
    Cell Significance Index: 7.1400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0587
    Cell Significance Index: 32.0800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0455
    Cell Significance Index: 16.3100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0419
    Cell Significance Index: 1.1700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0300
    Cell Significance Index: 1.4100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0286
    Cell Significance Index: 0.6100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0242
    Cell Significance Index: 0.8500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0242
    Cell Significance Index: 16.7400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0231
    Cell Significance Index: 2.9900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0188
    Cell Significance Index: 0.3900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0119
    Cell Significance Index: 1.5300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0013
    Cell Significance Index: -0.1000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0014
    Cell Significance Index: -2.6200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0046
    Cell Significance Index: -8.5000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0050
    Cell Significance Index: -7.6400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0066
    Cell Significance Index: -9.0000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0068
    Cell Significance Index: -5.0100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0082
    Cell Significance Index: -6.2400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0091
    Cell Significance Index: -0.5100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0095
    Cell Significance Index: -6.0600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0101
    Cell Significance Index: -0.2700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0113
    Cell Significance Index: -8.3400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0137
    Cell Significance Index: -0.9200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0149
    Cell Significance Index: -6.7600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0158
    Cell Significance Index: -8.9000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0176
    Cell Significance Index: -10.9700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0193
    Cell Significance Index: -1.9800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0201
    Cell Significance Index: -3.4400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0221
    Cell Significance Index: -1.1600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0265
    Cell Significance Index: -1.1700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0276
    Cell Significance Index: -0.5100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0277
    Cell Significance Index: -7.9700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0282
    Cell Significance Index: -0.9800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0329
    Cell Significance Index: -2.5300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0436
    Cell Significance Index: -1.6500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0508
    Cell Significance Index: -7.3900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0511
    Cell Significance Index: -5.8600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0522
    Cell Significance Index: -11.0100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0674
    Cell Significance Index: -0.9200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0762
    Cell Significance Index: -1.2800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0771
    Cell Significance Index: -2.4700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0785
    Cell Significance Index: -2.2500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0800
    Cell Significance Index: -4.9200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0847
    Cell Significance Index: -1.8600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0922
    Cell Significance Index: -9.6000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1016
    Cell Significance Index: -6.2300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1109
    Cell Significance Index: -8.7800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1168
    Cell Significance Index: -3.0700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.1265
    Cell Significance Index: -3.7200
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.1364
    Cell Significance Index: -1.5500
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.1390
    Cell Significance Index: -0.8400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1428
    Cell Significance Index: -3.6700
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: -0.1598
    Cell Significance Index: -1.7000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1620
    Cell Significance Index: -3.3900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1714
    Cell Significance Index: -2.4600
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.1762
    Cell Significance Index: -2.6400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1835
    Cell Significance Index: -9.2700
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1858
    Cell Significance Index: -2.8000
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.2027
    Cell Significance Index: -2.8800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2072
    Cell Significance Index: -3.5500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2104
    Cell Significance Index: -7.7300
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.2116
    Cell Significance Index: -2.1900
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.2201
    Cell Significance Index: -1.8000
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.2319
    Cell Significance Index: -2.9300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2393
    Cell Significance Index: -6.8300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** BRPF1 is a 240-kDa protein containing a bromodomain, a PHD finger, and a histone-binding domain. Its structure allows it to interact with histones, transcription factors, and other proteins to regulate gene expression. BRPF1 is highly conserved across species, suggesting its essential role in cellular processes. Its expression is widespread, with notable presence in germ cells, neurons, and epithelial cells. **Pathways and Functions:** BRPF1 is involved in various cellular processes, including: 1. **Chromatin organization and remodeling**: BRPF1 interacts with histones to regulate chromatin structure and facilitate gene expression. 2. **Gene expression regulation**: BRPF1 modulates transcriptional activity by interacting with transcription factors and histones. 3. **Acetyltransferase activity**: BRPF1 is a histone acetyltransferase (HAT) that acetylates histones, leading to increased transcriptional activity. 4. **Regulation of developmental processes**: BRPF1 is involved in the regulation of hematopoiesis, development, and cell differentiation. **Clinical Significance:** BRPF1 has been implicated in various diseases, including: 1. **Cancer**: BRPF1 is overexpressed in several types of cancer, including leukemia, lymphoma, and colon cancer. Its overexpression is associated with poor prognosis and increased tumor aggressiveness. 2. **Neurological disorders**: BRPF1 is involved in the regulation of neuronal development and function. Alterations in BRPF1 expression have been linked to neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. 3. **Hematological disorders**: BRPF1 is involved in the regulation of hematopoiesis. Alterations in BRPF1 expression have been linked to hematological disorders, such as leukemia and lymphoma. In conclusion, BRPF1 is a multifunctional protein that plays a critical role in regulating gene expression and chromatin organization. Its overexpression has been linked to various diseases, including cancer, neurological disorders, and hematological disorders. Further research is needed to fully understand the mechanisms by which BRPF1 regulates cellular processes and to explore its potential as a therapeutic target. **Recommendations:** 1. **Further research**: Investigate the mechanisms by which BRPF1 regulates gene expression and chromatin organization. 2. **Therapeutic targeting**: Explore the potential of BRPF1 as a therapeutic target for cancer and other diseases. 3. **Immunological applications**: Investigate the potential of BRPF1 as a biomarker for disease diagnosis and monitoring. By understanding the role of BRPF1 in gene regulation and chromatin organization, we can gain insights into the underlying mechanisms of various diseases and develop novel therapeutic strategies.

Genular Protein ID: 2124615319

Symbol: BRPF1_HUMAN

Name: N/A

UniProtKB Accession Codes:

P55201 B4DEZ6 Q7Z6E0 Q8TCM6 Q9UHI0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 4 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 16 Gene3D 3 GeneCards 1 GeneTree 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 16 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 63 PDBsum 63 PIR 1 PRINTS 1 PRO 1 PROSITE 8 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 2 RefSeq 4 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7906940

Title: BR140, a novel zinc-finger protein with homology to the TAF250 subunit of TFIID.

PubMed ID: 7906940

DOI: 10.1006/bbrc.1994.1162

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16387653

Title: ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

PubMed ID: 16387653

DOI: 10.1016/j.molcel.2005.12.007

PubMed ID: 18794358

Title: Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes.

PubMed ID: 18794358

DOI: 10.1128/mcb.01297-08

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 24065767

Title: Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity.

PubMed ID: 24065767

DOI: 10.1101/gad.223396.113

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25593309

Title: Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

PubMed ID: 25593309

DOI: 10.1101/gad.252189.114

PubMed ID: 20400950

Title: Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1.

PubMed ID: 20400950

DOI: 10.1038/nsmb.1797

PubMed ID: 21720545

Title: Structural and histone binding ability characterizations of human PWWP domains.

PubMed ID: 21720545

DOI: 10.1371/journal.pone.0018919

PubMed ID: 27939640

Title: Mutations in the chromatin regulator gene BRPF1 cause syndromic intellectual disability and deficient histone acetylation.

PubMed ID: 27939640

DOI: 10.1016/j.ajhg.2016.11.011

PubMed ID: 27939639

Title: Mutations in histone acetylase modifier BRPF1 cause an autosomal-dominant form of intellectual disability with associated ptosis.

PubMed ID: 27939639

DOI: 10.1016/j.ajhg.2016.11.010

Sequence Information:

  • Length: 1214
  • Mass: 137499
  • Checksum: 618F359F21F4CBF7
  • Sequence:
    • MGVDFDVKTF CHNLRATKPP YECPVETCRK VYKSYSGIEY HLYHYDHDNP PPPQQTPLRK 
HKKKGRQSRP ANKQSPSPSE VSQSPGREVM SYAQAQRMVE VDLHGRVHRI SIFDNLDVVS 
EDEEAPEEAP ENGSNKENTE TPAATPKSGK HKNKEKRKDS NHHHHHNVSA STTPKLPEVV 
YRELEQDTPD APPRPTSYYR YIEKSAEELD EEVEYDMDEE DYIWLDIMNE RRKTEGVSPI 
PQEIFEYLMD RLEKESYFES HNKGDPNALV DEDAVCCICN DGECQNSNVI LFCDMCNLAV 
HQECYGVPYI PEGQWLCRRC LQSPSRAVDC ALCPNKGGAF KQTDDGRWAH VVCALWIPEV 
CFANTVFLEP IDSIEHIPPA RWKLTCYICK QRGSGACIQC HKANCYTAFH VTCAQQAGLY 
MKMEPVRETG ANGTSFSVRK TAYCDIHTPP GSARRLPALS HSEGEEDEDE EEDEGKGWSS 
EKVKKAKAKS RIKMKKARKI LAEKRAAAPV VSVPCIPPHR LSKITNRLTI QRKSQFMQRL 
HSYWTLKRQS RNGVPLLRRL QTHLQSQRNC DQVGRDSEDK NWALKEQLKS WQRLRHDLER 
ARLLVELIRK REKLKRETIK VQQIAMEMQL TPFLILLRKT LEQLQEKDTG NIFSEPVPLS 
EVPDYLDHIK KPMDFFTMKQ NLEAYRYLNF DDFEEDFNLI VSNCLKYNAK DTIFYRAAVR 
LREQGGAVLR QARRQAEKMG IDFETGMHIP HSLAGDEATH HTEDAAEEER LVLLENQKHL 
PVEEQLKLLL ERLDEVNASK QSVGRSRRAK MIKKEMTALR RKLAHQRETG RDGPERHGPS 
SRGSLTPHPA ACDKDGQTDS AAEESSSQET SKGLGPNMSS TPAHEVGRRT SVLFSKKNPK 
TAGPPKRPGR PPKNRESQMT PSHGGSPVGP PQLPIMSSLR QRKRGRSPRP SSSSDSDSDK 
STEDPPMDLP ANGFSGGNQP VKKSFLVYRN DCSLPRSSSD SESSSSSSSS AASDRTSTTP 
SKQGRGKPSF SRGTFPEDSS EDTSGTENEA YSVGTGRGVG HSMVRKSLGR GAGWLSEDED 
SPLDALDLVW AKCRGYPSYP ALIIDPKMPR EGMFHHGVPI PVPPLEVLKL GEQMTQEARE 
HLYLVLFFDN KRTWQWLPRT KLVPLGVNQD LDKEKMLEGR KSNIRKSVQI AYHRALQHRS 
KVQGEQSSET SDSD

Genular Protein ID: 511170377

Symbol: A0A804HKY8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A804HKY8

Database IDs:

ARBA 8 Bgee 1 CDD 4 CTD 1 DisGeNET 1 EMBL 3 Ensembl 2 GO 5 Gene3D 3 GeneTree 1 HGNC 1 InterPro 16 NCBI Taxonomy 1 PANTHER 2 PRINTS 1 PROSITE 13 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 5 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 3 SUPFAM 3

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

Sequence Information:

  • Length: 1247
  • Mass: 140866
  • Checksum: 32E003DD335D9F9D
  • Sequence:
    • MGVDFDVKTF CHNLRATKPP YECPVETCRK VYKSYSGIEY HLYHYDHDNP PPPQQTPLRK 
HKKKGRQSRP ANKQSPSPSE VSQSPGREVM SYAQAQRMVE VDLHGRVHRI SIFDNLDVVS 
EDEEAPEEAP ENGSNKENTE TPAATPKSGK HKNKEKRKDS NHHHHHNVSA STTPKLPEVV 
YRELEQDTPD APPRPTSYYR YIEKSAEELD EEVEYDMDEE DYIWLDIMNE RRKTEGVSPI 
PQEIFEYLMD RLEKESYFES HNKGDPNALV DEDAVCCICN DGECQNSNVI LFCDMCNLAV 
HQECYGVPYI PEGQWLCRRC LQSPSRAVDC ALCPNKGGAF KQTDDGRWAH VVCALWIPEV 
CFANTVFLEP IDSIEHIPPA RWKLTCYICK QRGSGACIQC HKANCYTAFH VTCAQQAGLY 
MKMEPVRETG ANGTSFSVRK TAYCDIHTPP GSARRLPALS HSEGEEDEDE EEDEGKGWSS 
EKVKKAKAKS RIKMKKARKI LAEKRAAAPV VSVPCIPPHR LSKITNRLTI QRKSQFMQRL 
HSYWTLKRQS RNGVPLLRRL QTHLQSQRNC DQVGRDSEDK NWALKEQLKS WQRLRHDLER 
ARLLVELIRK REKLKRETIK VQQIAMEMQL TPFLILLRKT LEQLQEKDTG NIFSEPVPLS 
EVPDYLDHIK KPMDFFTMKQ NLEAYRYLNF DDFEEDFNLI VSNCLKYNAK DTIFYRAAVR 
LREQGGAVLR QARRQAEKMG IDFETGMHIP HSLAGDEATH HTEDAEEERL VLLENQKHLP 
VEEQLKLLLE RLDEVNASKQ SVGRSRRAKM IKKEMTALRR KLAHQRETGR DGPERHGPSS 
RGSLTPHPAA CDKDGQTDSA AEESSSQETS KGLGPNMSST PAHEVGRRTS VLFSKKNPKT 
AGPPKRPGRP PKNRESQMTP SHGGSPVGPP QLPIMSSLRQ RKRGRSPRPS SSSDSDSDKS 
TEDPPMDLPA NGFSGGNQPV KKSFLVYRND CSLPRSSSDS ESSSSSSSSA ASDRTSTTPS 
KQGRGKPSFS RGTFPEDSSE DTSGTENEAY SVGTGRGVGH SSKFPCPRPG MLGTQCQGLA 
SPPAADPPPL PHSCEVVRKS LGRGAGWLSE DEDSPLDALD LVWAKCRGYP SYPALIIDPK 
MPREGMFHHG VPIPVPPLEV LKLGEQMTQE AREHLYLVLF FDNKRTWQWL PRTKLVPLGV 
NQDLDKEKML EGRKSNIRKS VQIAYHRALQ HRSKVQGEQS SETSDSD

Genular Protein ID: 878631835

Symbol: A0A804HI52_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A804HI52

Database IDs:

ARBA 8 AlphaFoldDB 1 Bgee 1 CDD 4 CTD 1 DisGeNET 1 EMBL 1 Ensembl 2 GO 5 Gene3D 3 GeneTree 1 HGNC 1 InterPro 16 NCBI Taxonomy 1 PANTHER 2 PRINTS 1 PROSITE 13 PROSITE-ProRule 2 PeptideAtlas 2 Pfam 5 Proteomes 2 ProteomicsDB 1 RefSeq 2 SAM 1 SMART 3 SMR 1 SUPFAM 3

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

Sequence Information:

  • Length: 1248
  • Mass: 140937
  • Checksum: 568B65585E08AFE5
  • Sequence:
    • MGVDFDVKTF CHNLRATKPP YECPVETCRK VYKSYSGIEY HLYHYDHDNP PPPQQTPLRK 
HKKKGRQSRP ANKQSPSPSE VSQSPGREVM SYAQAQRMVE VDLHGRVHRI SIFDNLDVVS 
EDEEAPEEAP ENGSNKENTE TPAATPKSGK HKNKEKRKDS NHHHHHNVSA STTPKLPEVV 
YRELEQDTPD APPRPTSYYR YIEKSAEELD EEVEYDMDEE DYIWLDIMNE RRKTEGVSPI 
PQEIFEYLMD RLEKESYFES HNKGDPNALV DEDAVCCICN DGECQNSNVI LFCDMCNLAV 
HQECYGVPYI PEGQWLCRRC LQSPSRAVDC ALCPNKGGAF KQTDDGRWAH VVCALWIPEV 
CFANTVFLEP IDSIEHIPPA RWKLTCYICK QRGSGACIQC HKANCYTAFH VTCAQQAGLY 
MKMEPVRETG ANGTSFSVRK TAYCDIHTPP GSARRLPALS HSEGEEDEDE EEDEGKGWSS 
EKVKKAKAKS RIKMKKARKI LAEKRAAAPV VSVPCIPPHR LSKITNRLTI QRKSQFMQRL 
HSYWTLKRQS RNGVPLLRRL QTHLQSQRNC DQVGRDSEDK NWALKEQLKS WQRLRHDLER 
ARLLVELIRK REKLKRETIK VQQIAMEMQL TPFLILLRKT LEQLQEKDTG NIFSEPVPLS 
EVPDYLDHIK KPMDFFTMKQ NLEAYRYLNF DDFEEDFNLI VSNCLKYNAK DTIFYRAAVR 
LREQGGAVLR QARRQAEKMG IDFETGMHIP HSLAGDEATH HTEDAAEEER LVLLENQKHL 
PVEEQLKLLL ERLDEVNASK QSVGRSRRAK MIKKEMTALR RKLAHQRETG RDGPERHGPS 
SRGSLTPHPA ACDKDGQTDS AAEESSSQET SKGLGPNMSS TPAHEVGRRT SVLFSKKNPK 
TAGPPKRPGR PPKNRESQMT PSHGGSPVGP PQLPIMSSLR QRKRGRSPRP SSSSDSDSDK 
STEDPPMDLP ANGFSGGNQP VKKSFLVYRN DCSLPRSSSD SESSSSSSSS AASDRTSTTP 
SKQGRGKPSF SRGTFPEDSS EDTSGTENEA YSVGTGRGVG HSSKFPCPRP GMLGTQCQGL 
ASPPAADPPP LPHSCEVVRK SLGRGAGWLS EDEDSPLDAL DLVWAKCRGY PSYPALIIDP 
KMPREGMFHH GVPIPVPPLE VLKLGEQMTQ EAREHLYLVL FFDNKRTWQW LPRTKLVPLG 
VNQDLDKEKM LEGRKSNIRK SVQIAYHRAL QHRSKVQGEQ SSETSDSD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.