Details for: YEATS4
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 75.4122
Cell Significance Index: -11.7300 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 69.5070
Cell Significance Index: -17.6300 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 60.9179
Cell Significance Index: -25.1000 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 54.9116
Cell Significance Index: -25.9300 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 52.5529
Cell Significance Index: -21.3500 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 48.2129
Cell Significance Index: -24.8000 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 22.4249
Cell Significance Index: -21.4100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 19.4330
Cell Significance Index: -23.9600 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 7.3333
Cell Significance Index: -19.6500 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 6.5509
Cell Significance Index: -25.8500 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 4.8316
Cell Significance Index: -14.8400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.2453
Cell Significance Index: 1124.4200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.1135
Cell Significance Index: 70.1800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.8373
Cell Significance Index: 22.7900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.7393
Cell Significance Index: 25.6900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.7384
Cell Significance Index: 38.7700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.7315
Cell Significance Index: 86.2700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.5269
Cell Significance Index: 94.9900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.5169
Cell Significance Index: 228.5400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.5154
Cell Significance Index: 63.3700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.4588
Cell Significance Index: 31.7300 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.4166
Cell Significance Index: 227.5100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.4126
Cell Significance Index: 81.8800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.3942
Cell Significance Index: 20.4800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3482
Cell Significance Index: 56.6300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.3481
Cell Significance Index: 16.2300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.2943
Cell Significance Index: 59.0300 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.2931
Cell Significance Index: 20.7300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2791
Cell Significance Index: 8.0400 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.2469
Cell Significance Index: 18.4000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.2385
Cell Significance Index: 23.5900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.2151
Cell Significance Index: 10.1100 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.2072
Cell Significance Index: 2.4700 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.2043
Cell Significance Index: 26.4000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.1955
Cell Significance Index: 12.6100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.1773
Cell Significance Index: 5.6800 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.1772
Cell Significance Index: 3.8400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1731
Cell Significance Index: 62.1100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1668
Cell Significance Index: 7.5600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1537
Cell Significance Index: 29.2500 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1207
Cell Significance Index: 83.4600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.1169
Cell Significance Index: 6.5600 - Cell Name: peg cell (CL4033014)
Fold Change: 0.1130
Cell Significance Index: 2.6100 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.1106
Cell Significance Index: 14.1800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1015
Cell Significance Index: 13.9400 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.0846
Cell Significance Index: 0.9200 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.0262
Cell Significance Index: 0.6900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0161
Cell Significance Index: 0.4300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0159
Cell Significance Index: 0.5600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0071
Cell Significance Index: 1.2200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0044
Cell Significance Index: 8.2000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0038
Cell Significance Index: -2.9100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0096
Cell Significance Index: -14.7100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0097
Cell Significance Index: -7.0800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0106
Cell Significance Index: -19.5300 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0132
Cell Significance Index: -17.9500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0156
Cell Significance Index: -9.9100 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0174
Cell Significance Index: -0.4700 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.0192
Cell Significance Index: -0.4900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0247
Cell Significance Index: -18.2600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0249
Cell Significance Index: -0.5300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0328
Cell Significance Index: -14.8800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0368
Cell Significance Index: -3.7600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0374
Cell Significance Index: -21.1200 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0416
Cell Significance Index: -2.5600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0453
Cell Significance Index: -6.5900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0495
Cell Significance Index: -30.9400 - Cell Name: germ cell (CL0000586)
Fold Change: -0.0536
Cell Significance Index: -0.4100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0551
Cell Significance Index: -1.5400 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: -0.0610
Cell Significance Index: -0.4700 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.0628
Cell Significance Index: -0.6500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0675
Cell Significance Index: -19.4200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0678
Cell Significance Index: -1.4200 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.0869
Cell Significance Index: -0.8000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.1100
Cell Significance Index: -2.7500 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1111
Cell Significance Index: -1.8600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1149
Cell Significance Index: -13.1600 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1196
Cell Significance Index: -13.9400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1353
Cell Significance Index: -28.4900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.1556
Cell Significance Index: -4.5700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.1681
Cell Significance Index: -2.8800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1795
Cell Significance Index: -13.7800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2131
Cell Significance Index: -11.1000 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.2306
Cell Significance Index: -2.6200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2347
Cell Significance Index: -18.5900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2384
Cell Significance Index: -24.8200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.2683
Cell Significance Index: -3.6600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2942
Cell Significance Index: -18.0400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.3059
Cell Significance Index: -20.5700 - Cell Name: glioblast (CL0000030)
Fold Change: -0.3121
Cell Significance Index: -1.9600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.3334
Cell Significance Index: -8.5700 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.3408
Cell Significance Index: -9.1200 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.3448
Cell Significance Index: -15.2500 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.3728
Cell Significance Index: -10.9800 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.3731
Cell Significance Index: -8.1700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.4056
Cell Significance Index: -15.3600 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.4664
Cell Significance Index: -13.3700 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.5224
Cell Significance Index: -4.2600 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.5247
Cell Significance Index: -10.8900 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.5351
Cell Significance Index: -17.5200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1375578349
Symbol: YETS4_HUMAN
Name: NuMA-binding protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9302258
Title: Cloning of a novel transcription factor-like gene amplified in human glioma including astrocytoma grade I.
PubMed ID: 9302258
PubMed ID: 10913114
Title: GAS41, a highly conserved protein in eukaryotic nuclei, binds to NuMA.
PubMed ID: 10913114
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12963728
Title: Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex.
PubMed ID: 12963728
PubMed ID: 11903063
Title: Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells.
PubMed ID: 11903063
PubMed ID: 11756182
Title: The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex.
PubMed ID: 11756182
PubMed ID: 12620397
Title: Molecular cloning, genomic structure and interactions of the putative breast tumor suppressor TACC2.
PubMed ID: 12620397
PubMed ID: 15196461
Title: The highly conserved and multifunctional NuA4 HAT complex.
PubMed ID: 15196461
PubMed ID: 14966270
Title: Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.
PubMed ID: 14966270
PubMed ID: 18445686
Title: EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase.
PubMed ID: 18445686
DOI: 10.1242/jcs.019174
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 29437725
Title: Recognition of histone acetylation by the GAS41 YEATS domain promotes H2A.Z deposition in non-small cell lung cancer.
PubMed ID: 29437725
PubMed ID: 30071723
Title: GAS41 recognizes diacetylated histone H3 through a bivalent binding mode.
PubMed ID: 30071723
PubMed ID: 29900004
Title: Gas41 links histone acetylation to H2A.Z deposition and maintenance of embryonic stem cell identity.
PubMed ID: 29900004
PubMed ID: 29463709
Title: Identification of the YEATS domain of GAS41 as a pH-dependent reader of histone succinylation.
PubMed ID: 29463709
Sequence Information:
- Length: 227
- Mass: 26499
- Checksum: 34C4692B227A7B85
- Sequence:
MFKRMAEFGP DSGGRVKGVT IVKPIVYGNV ARYFGKKREE DGHTHQWTVY VKPYRNEDMS AYVKKIQFKL HESYGNPLRV VTKPPYEITE TGWGEFEIII KIFFIDPNER PVTLYHLLKL FQSDTNAMLG KKTVVSEFYD EMIFQDPTAM MQQLLTTSRQ LTLGAYKHET EFAELEVKTR EKLEAAKKKT SFEIAELKER LKASRETINC LKNEIRKLEE DDQAKDI
Genular Protein ID: 279072809
Symbol: F8W0J4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
Sequence Information:
- Length: 173
- Mass: 20131
- Checksum: 1E6954835FF324BE
- Sequence:
MFKRMAEFGP DSGGRVKGVT IVKPIVYGNV ARYFGKKREE DGHTHQWTVY VKPYRNEVTL YHLLKLFQSD TNAMLGKKTV VSEFYDEMIF QDPTAMMQQL LTTSRQLTLG AYKHETEFAE LEVKTREKLE AAKKKTSFEI AELKERLKAS RETINCLKNE IRKLEEDDQA KDI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.