Details for: COIL

Gene ID: 8161

Symbol: COIL

Ensembl ID: ENSG00000121058

Description: coilin

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 157.7033
    Cell Significance Index: -24.5300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 95.1730
    Cell Significance Index: -24.1400
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 67.6785
    Cell Significance Index: -27.8800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 55.9503
    Cell Significance Index: -28.7800
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 45.5574
    Cell Significance Index: -30.5700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 23.0179
    Cell Significance Index: -28.3800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 10.0117
    Cell Significance Index: -26.8200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 7.4251
    Cell Significance Index: -29.3000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 5.7790
    Cell Significance Index: -17.7500
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.2310
    Cell Significance Index: -9.2600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.7078
    Cell Significance Index: 277.7500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.3497
    Cell Significance Index: 1218.6800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.1305
    Cell Significance Index: 30.7700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.9828
    Cell Significance Index: 61.9400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.8957
    Cell Significance Index: 12.2200
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.6798
    Cell Significance Index: 7.3900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.6512
    Cell Significance Index: 13.6300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5896
    Cell Significance Index: 26.7200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.5012
    Cell Significance Index: 68.8400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4774
    Cell Significance Index: 86.0600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4759
    Cell Significance Index: 24.7200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.4633
    Cell Significance Index: 253.0200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4475
    Cell Significance Index: 55.0200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4392
    Cell Significance Index: 194.1800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4325
    Cell Significance Index: 12.4600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.4161
    Cell Significance Index: 11.1300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4081
    Cell Significance Index: 80.9800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.3608
    Cell Significance Index: 103.8100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.3597
    Cell Significance Index: 23.2100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3322
    Cell Significance Index: 22.9800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3224
    Cell Significance Index: 64.6700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.3020
    Cell Significance Index: 14.0800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.2777
    Cell Significance Index: 19.6400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2523
    Cell Significance Index: 48.0200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2384
    Cell Significance Index: 5.9600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2347
    Cell Significance Index: 30.0900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.2092
    Cell Significance Index: 7.2700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2085
    Cell Significance Index: 74.8000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.2017
    Cell Significance Index: 11.3200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1972
    Cell Significance Index: 23.2600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1886
    Cell Significance Index: 9.9000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1854
    Cell Significance Index: 18.3400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1705
    Cell Significance Index: 10.4800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.1584
    Cell Significance Index: 4.2300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1473
    Cell Significance Index: 101.8500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1090
    Cell Significance Index: 18.6200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1068
    Cell Significance Index: 5.0200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0948
    Cell Significance Index: 12.2500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0912
    Cell Significance Index: 2.5500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0621
    Cell Significance Index: 0.7400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0609
    Cell Significance Index: 1.3200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0569
    Cell Significance Index: 4.2400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0333
    Cell Significance Index: 1.1700
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.0132
    Cell Significance Index: 0.3100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0098
    Cell Significance Index: 18.4300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0048
    Cell Significance Index: 6.5900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0016
    Cell Significance Index: 2.9500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0014
    Cell Significance Index: 2.1300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0034
    Cell Significance Index: -0.1100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0045
    Cell Significance Index: -3.3500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0080
    Cell Significance Index: -5.1000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0088
    Cell Significance Index: -6.4400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0097
    Cell Significance Index: -6.0700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0146
    Cell Significance Index: -0.3100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0198
    Cell Significance Index: -14.9800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0209
    Cell Significance Index: -1.6000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0299
    Cell Significance Index: -13.5600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0336
    Cell Significance Index: -18.9600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0356
    Cell Significance Index: -0.6000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0584
    Cell Significance Index: -5.9700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0671
    Cell Significance Index: -14.1300
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: -0.0727
    Cell Significance Index: -0.4500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1175
    Cell Significance Index: -17.0800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1212
    Cell Significance Index: -13.8900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1273
    Cell Significance Index: -2.6400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1454
    Cell Significance Index: -16.9500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1739
    Cell Significance Index: -2.9800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1932
    Cell Significance Index: -5.0800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1951
    Cell Significance Index: -4.9800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2467
    Cell Significance Index: -28.1700
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.2491
    Cell Significance Index: -2.8300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2571
    Cell Significance Index: -17.2900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2660
    Cell Significance Index: -27.7000
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.2734
    Cell Significance Index: -2.8300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.2816
    Cell Significance Index: -8.2700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3030
    Cell Significance Index: -24.0000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3129
    Cell Significance Index: -8.9700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3224
    Cell Significance Index: -14.2600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.3575
    Cell Significance Index: -2.1600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3731
    Cell Significance Index: -9.5900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.4122
    Cell Significance Index: -15.6100
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.4366
    Cell Significance Index: -3.5600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.4845
    Cell Significance Index: -11.6200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4879
    Cell Significance Index: -29.9100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.5049
    Cell Significance Index: -13.5300
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.5214
    Cell Significance Index: -4.3800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.5395
    Cell Significance Index: -10.5300
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.5558
    Cell Significance Index: -7.5000
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.5969
    Cell Significance Index: -17.5800
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.6313
    Cell Significance Index: -9.4600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Coilin's role in nuclear organization**: Coilin is a major component of Cajal bodies, which are nuclear structures responsible for the assembly and maturation of small nuclear RNAs (snRNAs). Its presence is essential for the formation and function of these bodies, which in turn regulate gene expression. 2. **Protein binding properties**: Coilin exhibits a high degree of protein binding affinity, interacting with various proteins involved in spliceosomal snRNP assembly, U1 and U2 snRNA binding, and other nuclear processes. 3. **Cell type specificity**: Coilin's expression is restricted to a subset of cell types, including pre-B cells, large pre-B-II cells, proerythroblasts, and cerebral cortex GABAergic interneurons, suggesting a specialized function in these cells. 4. **Evolutionary conservation**: Coilin's conservation across species, including humans, mice, and zebrafish, underscores its fundamental importance in maintaining nuclear structure and function. **Pathways and Functions:** 1. **Spliceosomal snRNP assembly**: Coilin's involvement in spliceosomal snRNP assembly highlights its role in regulating the processing of pre-mRNA, a critical step in gene expression. 2. **Cajal body formation and function**: Coilin's presence in Cajal bodies is essential for their formation and function, which in turn regulate the assembly and maturation of snRNAs. 3. **U1 and U2 snRNA binding**: Coilin's interaction with U1 and U2 snRNAs suggests its involvement in the regulation of alternative splicing and gene expression. 4. **Nuclear organization and dynamics**: Coilin's role in maintaining the structure and dynamics of the nucleus, particularly in the context of Cajal bodies and fibrillar centers, underscores its importance in regulating gene expression and cellular processes. **Clinical Significance:** Coilin's involvement in various cellular processes, including spliceosomal snRNP assembly and nuclear organization, suggests its potential role in the pathogenesis of diseases characterized by abnormal gene expression, such as cancer and neurological disorders. Furthermore, coilin's expression in specific cell types highlights its potential as a biomarker for these diseases. Future studies aimed at elucidating coilin's function and regulation in healthy and diseased states will provide valuable insights into its clinical significance. In summary, coilin is a multifunctional protein that plays a critical role in maintaining nuclear structure and function, regulating gene expression, and participating in spliceosomal snRNP assembly. Its involvement in various cellular processes underscores its significance in both healthy and diseased states, highlighting the need for further research into its clinical significance.

Genular Protein ID: 2640711021

Symbol: COIL_HUMAN

Name: Coilin

UniProtKB Accession Codes:

P38432 B2R931

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 1 ExpressionAtlas 1 GO 12 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SIGNOR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7971277

Title: Structure, expression and chromosomal localization of human p80-coilin gene.

PubMed ID: 7971277

DOI: 10.1093/nar/22.21.4462

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2033369

Title: Human autoantibody to a novel protein of the nuclear coiled body: immunological characterization and cDNA cloning of p80-coilin.

PubMed ID: 2033369

DOI: 10.1084/jem.173.6.1407

PubMed ID: 7679389

Title: Assembly of snRNP-containing coiled bodies is regulated in interphase and mitosis -- evidence that the coiled body is a kinetic nuclear structure.

PubMed ID: 7679389

DOI: 10.1083/jcb.120.4.841

PubMed ID: 11641277

Title: Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein.

PubMed ID: 11641277

DOI: 10.1101/gad.908401

PubMed ID: 12361597

Title: Coilin methylation regulates nuclear body formation.

PubMed ID: 12361597

DOI: 10.1016/s1534-5807(02)00222-8

PubMed ID: 15862129

Title: A novel EB-1/AIDA-1 isoform, AIDA-1c, interacts with the Cajal body protein coilin.

PubMed ID: 15862129

DOI: 10.1186/1471-2121-6-23

PubMed ID: 16079131

Title: Characterization of hCINAP, a novel coilin-interacting protein encoded by a transcript from the transcription factor TAFIID32 locus.

PubMed ID: 16079131

DOI: 10.1074/jbc.m501982200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21072240

Title: WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies.

PubMed ID: 21072240

DOI: 10.1371/journal.pbio.1000521

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21920476

Title: Substrate profiling of human vaccinia-related kinases identifies coilin, a Cajal body nuclear protein, as a phosphorylation target with neurological implications.

PubMed ID: 21920476

DOI: 10.1016/j.jprot.2011.08.019

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22547674

Title: Telomerase recruitment requires both TCAB1 and Cajal bodies independently.

PubMed ID: 22547674

DOI: 10.1128/mcb.00379-12

PubMed ID: 23685356

Title: HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment.

PubMed ID: 23685356

DOI: 10.1038/emboj.2013.105

PubMed ID: 23726919

Title: Human UBL5 protein interacts with coilin and meets the Cajal bodies.

PubMed ID: 23726919

DOI: 10.1016/j.bbrc.2013.05.083

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 29934401

Title: PIP30/FAM192A is a novel regulator of the nuclear proteasome activator PA28gamma.

PubMed ID: 29934401

DOI: 10.1073/pnas.1722299115

PubMed ID: 31527692

Title: VRK1 functional insufficiency due to alterations in protein stability or kinase activity of human VRK1 pathogenic variants implicated in neuromotor syndromes.

PubMed ID: 31527692

DOI: 10.1038/s41598-019-49821-7

PubMed ID: 20875822

Title: Solution structure of the carboxy-terminal Tudor domain from human Coilin.

PubMed ID: 20875822

DOI: 10.1016/j.febslet.2010.09.034

Sequence Information:

  • Length: 576
  • Mass: 62608
  • Checksum: 879702B590F16849
  • Sequence:
    • MAASETVRLR LQFDYPPPAT PHCTAFWLLV DLNRCRVVTD LISLIRQRFG FSSGAFLGLY 
LEGGLLPPAE SARLVRDNDC LRVKLEERGV AENSVVISNG DINLSLRKAK KRAFQLEEGE 
ETEPDCKYSK KHWKSRENNN NNEKVLDLEP KAVTDQTVSK KNKRKNKATC GTVGDDNEEA 
KRKSPKKKEK CEYKKKAKNP KSPKVQAVKD WANQRCSSPK GSARNSLVKA KRKGSVSVCS 
KESPSSSSES ESCDESISDG PSKVTLEARN SSEKLPTELS KEEPSTKNTT ADKLAIKLGF 
SLTPSKGKTS GTTSSSSDSS AESDDQCLMS SSTPECAAGF LKTVGLFAGR GRPGPGLSSQ 
TAGAAGWRRS GSNGGGQAPG ASPSVSLPAS LGRGWGREEN LFSWKGAKGR GMRGRGRGRG 
HPVSCVVNRS TDNQRQQQLN DVVKNSSTII QNPVETPKKD YSLLPLLAAA PQVGEKIAFK 
LLELTSSYSP DVSDYKEGRI LSHNPETQQV DIEILSSLPA LREPGKFDLV YHNENGAEVV 
EYAVTQESKI TVFWKELIDP RLIIESPSNT SSTEPA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.