Details for: MKKS

Gene ID: 8195

Symbol: MKKS

Ensembl ID: ENSG00000125863

Description: MKKS centrosomal shuttling protein

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 125.1726
    Cell Significance Index: -19.4700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 87.0711
    Cell Significance Index: -22.0900
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 72.2422
    Cell Significance Index: -29.7600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 63.3835
    Cell Significance Index: -25.7500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 62.8438
    Cell Significance Index: -29.6700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 44.5440
    Cell Significance Index: -29.8900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 27.4262
    Cell Significance Index: -26.1900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 21.2416
    Cell Significance Index: -26.1900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.5671
    Cell Significance Index: -22.9500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 7.0932
    Cell Significance Index: -27.9900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 5.1441
    Cell Significance Index: -15.8000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.4549
    Cell Significance Index: 76.3900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.3336
    Cell Significance Index: 1204.1600
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 0.9873
    Cell Significance Index: 10.4900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.9843
    Cell Significance Index: 680.7800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.9699
    Cell Significance Index: 58.2300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9042
    Cell Significance Index: 147.0600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.9023
    Cell Significance Index: 492.7500
  • Cell Name: columnar/cuboidal epithelial cell (CL0000075)
    Fold Change: 0.8827
    Cell Significance Index: 3.3800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.8156
    Cell Significance Index: 38.0300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.5301
    Cell Significance Index: 106.3300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.5164
    Cell Significance Index: 32.5500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5125
    Cell Significance Index: 23.2300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5117
    Cell Significance Index: 35.3900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.4259
    Cell Significance Index: 22.1900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4186
    Cell Significance Index: 57.4800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3622
    Cell Significance Index: 71.8700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3319
    Cell Significance Index: 7.1900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3103
    Cell Significance Index: 8.9400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2980
    Cell Significance Index: 29.4800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.2889
    Cell Significance Index: 10.0400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2833
    Cell Significance Index: 53.9100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.2789
    Cell Significance Index: 5.9600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2749
    Cell Significance Index: 32.4200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2534
    Cell Significance Index: 90.8800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2312
    Cell Significance Index: 6.4600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.2200
    Cell Significance Index: 5.9000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2144
    Cell Significance Index: 38.6500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2030
    Cell Significance Index: 26.0200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1893
    Cell Significance Index: 83.7000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1529
    Cell Significance Index: 18.8000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.1052
    Cell Significance Index: 3.0900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0897
    Cell Significance Index: 1.9100
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.0889
    Cell Significance Index: 0.7100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0752
    Cell Significance Index: 2.4100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0686
    Cell Significance Index: 2.4100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0679
    Cell Significance Index: 0.8100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0500
    Cell Significance Index: 37.8400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0354
    Cell Significance Index: 0.9300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.0268
    Cell Significance Index: 0.5600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0164
    Cell Significance Index: 0.2800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0091
    Cell Significance Index: 1.5500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0070
    Cell Significance Index: 0.5300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0062
    Cell Significance Index: 0.4400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0076
    Cell Significance Index: -14.2900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0088
    Cell Significance Index: -0.1200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0100
    Cell Significance Index: -7.3100
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0120
    Cell Significance Index: -0.1800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0133
    Cell Significance Index: -24.5600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0159
    Cell Significance Index: -24.4800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0173
    Cell Significance Index: -1.7700
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0199
    Cell Significance Index: -0.3000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0209
    Cell Significance Index: -28.4400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0219
    Cell Significance Index: -1.1400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0291
    Cell Significance Index: -21.5700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0310
    Cell Significance Index: -19.6800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0434
    Cell Significance Index: -24.4900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0435
    Cell Significance Index: -19.7300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0443
    Cell Significance Index: -0.7600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0507
    Cell Significance Index: -31.6600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0560
    Cell Significance Index: -6.4100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0577
    Cell Significance Index: -1.5700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0736
    Cell Significance Index: -21.1800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0877
    Cell Significance Index: -2.2400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1045
    Cell Significance Index: -15.1900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1370
    Cell Significance Index: -8.8400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1446
    Cell Significance Index: -30.4500
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.1532
    Cell Significance Index: -2.9900
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.1571
    Cell Significance Index: -1.3200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1724
    Cell Significance Index: -11.6000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1749
    Cell Significance Index: -22.5900
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.1757
    Cell Significance Index: -1.9100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2438
    Cell Significance Index: -11.4600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2510
    Cell Significance Index: -18.7100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2643
    Cell Significance Index: -11.6900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2669
    Cell Significance Index: -27.7900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2720
    Cell Significance Index: -21.5400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2843
    Cell Significance Index: -7.5900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3338
    Cell Significance Index: -12.6400
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.3386
    Cell Significance Index: -2.6100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3646
    Cell Significance Index: -20.4600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3755
    Cell Significance Index: -23.0200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3929
    Cell Significance Index: -10.1000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.4123
    Cell Significance Index: -8.7500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.4424
    Cell Significance Index: -4.5800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4941
    Cell Significance Index: -12.3500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.5135
    Cell Significance Index: -18.8500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.5162
    Cell Significance Index: -16.4400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.5181
    Cell Significance Index: -15.2600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.5464
    Cell Significance Index: -17.8900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Centrosomal shuttling protein**: MKKS is a protein that shuttles between the centrosome and the cytosol, playing a critical role in regulating centrosome function and microtubule dynamics. 2. **Widespread expression**: MKKS is expressed in various cell types, including myeloid leukocytes, stratified epithelial cells, and neurons, suggesting its importance in multiple biological processes. 3. **Multiple pathways involvement**: MKKS has been implicated in various signaling pathways, including those involved in development, cell signaling, and sensory perception. 4. **Disease association**: MKKS has been associated with Bardet-Biedl syndrome, a rare genetic disorder characterized by obesity, polydactyly, and renal anomalies. **Pathways and Functions:** 1. **Centrosome function**: MKKS regulates centrosome function and microtubule dynamics, which are essential for cell division, migration, and axon guidance. 2. **Cargo targeting to cilium**: MKKS is involved in targeting cargo proteins to the cilium, a critical structure involved in sensory perception and cell signaling. 3. **Cilium assembly**: MKKS is required for cilium assembly and maintenance, which is essential for sensory perception and cell signaling. 4. **Sensory perception**: MKKS is involved in sensory perception, including the detection of mechanical stimuli and the perception of smell and sound. 5. **Developmental processes**: MKKS is required for developmental processes, including brain morphogenesis, cerebral cortex development, and heart development. **Clinical Significance:** 1. **Bardet-Biedl syndrome**: MKKS mutations have been associated with Bardet-Biedl syndrome, a rare genetic disorder characterized by obesity, polydactyly, and renal anomalies. 2. **Ciliopathy**: MKKS mutations have also been associated with ciliopathies, a group of disorders characterized by defects in cilia structure and function. 3. **Sensory perception disorders**: MKKS mutations have been implicated in sensory perception disorders, including those affecting the detection of mechanical stimuli and the perception of smell and sound. 4. **Cancer**: MKKS has been implicated in cancer, particularly in the development of renal cell carcinoma and other cancers associated with ciliopathies. In conclusion, the MKKS gene is a critical component of multiple biological processes, including development, cell signaling, and sensory perception. Its involvement in Bardet-Biedl syndrome and ciliopathies highlights the importance of this gene in human health and disease. Further research is needed to fully understand the functions of MKKS and its role in human disease.

Genular Protein ID: 3582799311

Symbol: MKKS_HUMAN

Name: Bardet-Biedl syndrome 6 protein

UniProtKB Accession Codes:

Q9NPJ1 A8K7B0 D3DW18

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChEBI 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 3 GO 44 Gene3D 3 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 5 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 10802661

Title: Mutation of a gene encoding a putative chaperonin causes McKusick-Kaufman syndrome.

PubMed ID: 10802661

DOI: 10.1038/75637

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15731008

Title: MKKS/BBS6, a divergent chaperonin-like protein linked to the obesity disorder Bardet-Biedl syndrome, is a novel centrosomal component required for cytokinesis.

PubMed ID: 15731008

DOI: 10.1242/jcs.01676

PubMed ID: 16327777

Title: Dissection of epistasis in oligogenic Bardet-Biedl syndrome.

PubMed ID: 16327777

DOI: 10.1038/nature04370

PubMed ID: 18094050

Title: MKKS is a centrosome-shuttling protein degraded by disease-causing mutations via CHIP-mediated ubiquitination.

PubMed ID: 18094050

DOI: 10.1091/mbc.e07-07-0631

PubMed ID: 20080638

Title: BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly.

PubMed ID: 20080638

DOI: 10.1073/pnas.0910268107

PubMed ID: 26900326

Title: A novel H395R mutation in MKKS/BBS6 causes retinitis pigmentosa and polydactyly without other findings of Bardet-Biedl or McKusick-Kaufman syndrome.

PubMed ID: 26900326

PubMed ID: 33144677

Title: Dlec1 is required for spermatogenesis and male fertility in mice.

PubMed ID: 33144677

DOI: 10.1038/s41598-020-75957-y

PubMed ID: 10973238

Title: Mutations in MKKS cause Bardet-Biedl syndrome.

PubMed ID: 10973238

DOI: 10.1038/79116

PubMed ID: 10973251

Title: Mutations in MKKS cause obesity, retinal dystrophy and renal malformations associated with Bardet-Biedl syndrome.

PubMed ID: 10973251

DOI: 10.1038/79201

PubMed ID: 11179009

Title: Genetic and mutational analyses of a large multiethnic Bardet-Biedl cohort reveal a minor involvement of BBS6 and delineate the critical intervals of other loci.

PubMed ID: 11179009

DOI: 10.1086/318794

PubMed ID: 11567139

Title: Triallelic inheritance in Bardet-Biedl syndrome, a Mendelian recessive disorder.

PubMed ID: 11567139

DOI: 10.1126/science.1063525

PubMed ID: 12107442

Title: Mutation analysis of the MKKS gene in McKusick-Kaufman syndrome and selected Bardet-Biedl syndrome patients.

PubMed ID: 12107442

DOI: 10.1007/s00439-002-0733-3

PubMed ID: 12677556

Title: Genetic interaction of BBS1 mutations with alleles at other BBS loci can result in non-Mendelian Bardet-Biedl syndrome.

PubMed ID: 12677556

DOI: 10.1086/375178

PubMed ID: 12837689

Title: Heterozygous mutations in BBS1, BBS2 and BBS6 have a potential epistatic effect on Bardet-Biedl patients with two mutations at a second BBS locus.

PubMed ID: 12837689

DOI: 10.1093/hmg/ddg188

PubMed ID: 12920096

Title: Further support for digenic inheritance in Bardet-Biedl syndrome.

PubMed ID: 12920096

DOI: 10.1136/jmg.40.8.e104

PubMed ID: 15666242

Title: Antenatal presentation of Bardet-Biedl syndrome may mimic Meckel syndrome.

PubMed ID: 15666242

DOI: 10.1086/428679

PubMed ID: 15770229

Title: Testing for triallelism: analysis of six BBS genes in a Bardet-Biedl syndrome family cohort.

PubMed ID: 15770229

DOI: 10.1038/sj.ejhg.5201372

PubMed ID: 15483080

Title: Variation of the McKusick-Kaufman gene and studies of relationships with common forms of obesity.

PubMed ID: 15483080

DOI: 10.1210/jc.2004-0465

PubMed ID: 20120035

Title: Bardet-Biedl syndrome in Denmark -- report of 13 novel sequence variations in six genes.

PubMed ID: 20120035

DOI: 10.1002/humu.21204

PubMed ID: 21344540

Title: BBS genotype-phenotype assessment of a multiethnic patient cohort calls for a revision of the disease definition.

PubMed ID: 21344540

DOI: 10.1002/humu.21480

PubMed ID: 22152675

Title: TMEM237 is mutated in individuals with a Joubert syndrome related disorder and expands the role of the TMEM family at the ciliary transition zone.

PubMed ID: 22152675

DOI: 10.1016/j.ajhg.2011.11.005

PubMed ID: 28761321

Title: Sequence variants in four genes underlying Bardet-Biedl syndrome in consanguineous families.

PubMed ID: 28761321

PubMed ID: 28753627

Title: Nuclear/cytoplasmic transport defects in BBS6 underlie congenital heart disease through perturbation of a chromatin remodeling protein.

PubMed ID: 28753627

DOI: 10.1371/journal.pgen.1006936

Sequence Information:

  • Length: 570
  • Mass: 62342
  • Checksum: 14BA57FF8AEA0AF7
  • Sequence:
    • MSRLEAKKPS LCKSEPLTTE RVRTTLSVLK RIVTSCYGPS GRLKQLHNGF GGYVCTTSQS 
SALLSHLLVT HPILKILTAS IQNHVSSFSD CGLFTAILCC NLIENVQRLG LTPTTVIRLN 
KHLLSLCISY LKSETCGCRI PVDFSSTQIL LCLVRSILTS KPACMLTRKE TEHVSALILR 
AFLLTIPENA EGHIILGKSL IVPLKGQRVI DSTVLPGILI EMSEVQLMRL LPIKKSTALK 
VALFCTTLSG DTSDTGEGTV VVSYGVSLEN AVLDQLLNLG RQLISDHVDL VLCQKVIHPS 
LKQFLNMHRI IAIDRIGVTL MEPLTKMTGT QPIGSLGSIC PNSYGSVKDV CTAKFGSKHF 
FHLIPNEATI CSLLLCNRND TAWDELKLTC QTALHVLQLT LKEPWALLGG GCTETHLAAY 
IRHKTHNDPE SILKDDECTQ TELQLIAEAF CSALESVVGS LEHDGGEILT DMKYGHLWSV 
QADSPCVANW PDLLSQCGCG LYNSQEELNW SFLRSTRRPF VPQSCLPHEA VGSASNLTLD 
CLTAKLSGLQ VAVETANLIL DLSYVIEDKN

Genular Protein ID: 3025974976

Symbol: B7Z3W9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z3W9

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 9 InterPro 1 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 RefSeq 2

Sequence Information:

  • Length: 99
  • Mass: 10929
  • Checksum: 43AC1EE25B412BA0
  • Sequence:
    • MKYGHLWSVQ ADSPCVANWP DLLSQCGCGL YNSQEELNWS FLRSTRRPFV PQSCLPHEAV 
GSASNLTLDC LTAKLSGLQV AVETANLILD LSYVIEDKN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.