Details for: USP9X

Gene ID: 8239

Symbol: USP9X

Ensembl ID: ENSG00000124486

Description: ubiquitin specific peptidase 9 X-linked

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 394.7405
    Cell Significance Index: -61.4000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 249.4053
    Cell Significance Index: -63.2600
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 168.0311
    Cell Significance Index: -69.2200
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 142.1029
    Cell Significance Index: -67.0900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 134.6438
    Cell Significance Index: -54.7000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 123.8566
    Cell Significance Index: -63.7100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 57.6438
    Cell Significance Index: -55.0400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 52.3944
    Cell Significance Index: -64.6000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 23.3084
    Cell Significance Index: -62.4400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 18.8250
    Cell Significance Index: -57.8200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 16.7813
    Cell Significance Index: -66.2200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 15.8915
    Cell Significance Index: -34.7800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 3.2443
    Cell Significance Index: 527.6500
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 2.6729
    Cell Significance Index: 45.0300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 2.5843
    Cell Significance Index: 69.0100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.2736
    Cell Significance Index: 451.2100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.0632
    Cell Significance Index: 413.8800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.0545
    Cell Significance Index: 115.2900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.8884
    Cell Significance Index: 48.5400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 1.6538
    Cell Significance Index: 41.3400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.5227
    Cell Significance Index: 546.1600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.2417
    Cell Significance Index: 858.8000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.2410
    Cell Significance Index: 64.6400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.0863
    Cell Significance Index: 83.3600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.9427
    Cell Significance Index: 115.9100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.8581
    Cell Significance Index: 52.7400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.8283
    Cell Significance Index: 23.8700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.8269
    Cell Significance Index: 23.1100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.8049
    Cell Significance Index: 145.1100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7706
    Cell Significance Index: 695.8200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.7306
    Cell Significance Index: 398.9900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.7100
    Cell Significance Index: 19.0300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.5422
    Cell Significance Index: 36.4600
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.5203
    Cell Significance Index: 12.0200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4606
    Cell Significance Index: 63.2600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4397
    Cell Significance Index: 47.8300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4357
    Cell Significance Index: 19.7500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.4274
    Cell Significance Index: 804.6600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4212
    Cell Significance Index: 29.1300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3451
    Cell Significance Index: 152.5900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.3054
    Cell Significance Index: 193.9900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.2818
    Cell Significance Index: 5.5000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.2342
    Cell Significance Index: 360.5700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.2143
    Cell Significance Index: 5.1400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1964
    Cell Significance Index: 362.1300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.1872
    Cell Significance Index: 8.2800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1832
    Cell Significance Index: 8.5400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1776
    Cell Significance Index: 80.6000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1626
    Cell Significance Index: 19.1800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1481
    Cell Significance Index: 28.1900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1403
    Cell Significance Index: 2.4100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1344
    Cell Significance Index: 13.3000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1160
    Cell Significance Index: 7.4900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1091
    Cell Significance Index: 5.6700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1047
    Cell Significance Index: 4.9200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0860
    Cell Significance Index: 116.9500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0445
    Cell Significance Index: 1.6900
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.0398
    Cell Significance Index: 0.8500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0068
    Cell Significance Index: -0.2400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0124
    Cell Significance Index: -2.1100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0230
    Cell Significance Index: -2.9500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0245
    Cell Significance Index: -17.9600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0566
    Cell Significance Index: -41.9500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0678
    Cell Significance Index: -51.3100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0762
    Cell Significance Index: -4.8000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0781
    Cell Significance Index: -2.2300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0973
    Cell Significance Index: -54.9000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1178
    Cell Significance Index: -73.5800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1186
    Cell Significance Index: -12.1200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1833
    Cell Significance Index: -26.6500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1859
    Cell Significance Index: -5.0600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1959
    Cell Significance Index: -56.3600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2060
    Cell Significance Index: -26.6200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2251
    Cell Significance Index: -26.2300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.3100
    Cell Significance Index: -21.9200
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.3128
    Cell Significance Index: -1.8900
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.3307
    Cell Significance Index: -3.0500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3327
    Cell Significance Index: -70.0800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3330
    Cell Significance Index: -34.6700
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.3546
    Cell Significance Index: -5.1000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3762
    Cell Significance Index: -28.0400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3796
    Cell Significance Index: -43.4900
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.4072
    Cell Significance Index: -6.0100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.5233
    Cell Significance Index: -7.1400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.5690
    Cell Significance Index: -16.3100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5910
    Cell Significance Index: -15.5400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.6338
    Cell Significance Index: -38.0500
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.6484
    Cell Significance Index: -15.8200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6832
    Cell Significance Index: -54.1100
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.6893
    Cell Significance Index: -8.5500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.7550
    Cell Significance Index: -16.0800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.7665
    Cell Significance Index: -24.5500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.8514
    Cell Significance Index: -44.7000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.9139
    Cell Significance Index: -56.0300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.9171
    Cell Significance Index: -13.5400
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.9185
    Cell Significance Index: -13.1900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.9965
    Cell Significance Index: -21.8200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.0757
    Cell Significance Index: -37.3800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.1497
    Cell Significance Index: -37.6400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.2010
    Cell Significance Index: -38.2500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** USP9X is a cysteine-type deubiquitinase enzyme that belongs to the peptidase FAF family. It is characterized by its ability to remove ubiquitin chains from protein substrates, thereby regulating protein degradation, localization, and activity. USP9X is also known for its involvement in various signaling pathways, including BMP signaling, Rho GTPase cycle, and transforming growth factor beta receptor signaling pathway. Its expression is restricted to specific cell types, suggesting a tissue-specific function. **Pathways and Functions** USP9X is involved in numerous cellular processes, including: 1. **Protein Degradation**: USP9X regulates protein degradation by removing ubiquitin chains from protein substrates, thereby modulating protein turnover and cellular homeostasis. 2. **Cell Migration**: USP9X is involved in cell migration, particularly in the development and maintenance of the nervous system, where it regulates the localization and activity of key signaling molecules. 3. **Signaling Pathways**: USP9X modulates various signaling pathways, including BMP signaling, Rho GTPase cycle, and transforming growth factor beta receptor signaling pathway, thereby regulating cellular responses to external stimuli. 4. **Circadian Rhythm**: USP9X is involved in the regulation of circadian rhythm, suggesting a role in maintaining the body's internal clock. 5. **Protein Localization**: USP9X regulates protein localization by removing ubiquitin chains from protein substrates, thereby modulating protein activity and cellular processes. **Clinical Significance** Dysregulation of USP9X has been implicated in various diseases, including: 1. **Cancer**: USP9X is overexpressed in several types of cancer, including breast, lung, and colon cancer, suggesting a role in tumorigenesis and cancer progression. 2. **Neurological Disorders**: USP9X is involved in the regulation of protein degradation and signaling pathways in the nervous system, and its dysregulation has been implicated in neurological disorders, including Alzheimer's disease and Parkinson's disease. 3. **Developmental Disorders**: USP9X is involved in the regulation of cell migration and signaling pathways during development, and its dysregulation has been implicated in developmental disorders, including neural tube defects and cleft palate. In conclusion, USP9X is a critical regulator of protein degradation, cell migration, and signaling pathways, and its dysregulation has been implicated in various diseases. Further research is needed to fully understand the mechanisms by which USP9X regulates cellular processes and to develop therapeutic strategies for diseases associated with USP9X dysregulation.

Genular Protein ID: 4200933954

Symbol: USP9X_HUMAN

Name: Ubiquitin carboxyl-terminal hydrolase 9X

UniProtKB Accession Codes:

Q93008 O75550 Q8WWT3 Q8WX12

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChEBI 4 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 4 EMDB 2 Ensembl 3 GO 42 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MEROPS 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 7 RefSeq 2 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8922996

Title: The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.

PubMed ID: 8922996

DOI: 10.1093/hmg/5.11.1695

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 16322459

Title: Chromosome alignment and segregation regulated by ubiquitination of survivin.

PubMed ID: 16322459

DOI: 10.1126/science.1120160

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17693683

Title: Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction.

PubMed ID: 17693683

DOI: 10.1074/mcp.m700120-mcp200

PubMed ID: 18254724

Title: Control of AMPK-related kinases by USP9X and atypical Lys(29)/Lys(33)-linked polyubiquitin chains.

PubMed ID: 18254724

DOI: 10.1042/bj20080067

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19135894

Title: FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination.

PubMed ID: 19135894

DOI: 10.1016/j.cell.2008.10.051

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944111

Title: Noncanonical regulation of alkylation damage resistance by the OTUD4 deubiquitinase.

PubMed ID: 25944111

DOI: 10.15252/embj.201490497

PubMed ID: 22371489

Title: Identification of ubiquitin-specific protease 9X (USP9X) as a deubiquitinase acting on ubiquitin-peroxin 5 (PEX5) thioester conjugate.

PubMed ID: 22371489

DOI: 10.1074/jbc.m112.340158

PubMed ID: 26598551

Title: Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition.

PubMed ID: 26598551

DOI: 10.15252/embr.201540809

PubMed ID: 29626158

Title: Deubiquitinating enzyme USP9X regulates cellular clock function by modulating the ubiquitination and degradation of a core circadian protein BMAL1.

PubMed ID: 29626158

DOI: 10.1042/bcj20180005

PubMed ID: 33378666

Title: mTORC2 Assembly Is Regulated by USP9X-Mediated Deubiquitination of RICTOR.

PubMed ID: 33378666

DOI: 10.1016/j.celrep.2020.108564

PubMed ID: 34404733

Title: AMOTL2 mono-ubiquitination by WWP1 promotes contact inhibition by facilitating LATS activation.

PubMed ID: 34404733

DOI: 10.26508/lsa.202000953

PubMed ID: 37454738

Title: Deubiquitinase USP9X stabilizes RNA m6A demethylase ALKBH5 and promotes acute myeloid leukemia cell survival.

PubMed ID: 37454738

DOI: 10.1016/j.jbc.2023.105055

PubMed ID: 24607389

Title: Mutations in USP9X are associated with X-linked intellectual disability and disrupt neuronal cell migration and growth.

PubMed ID: 24607389

DOI: 10.1016/j.ajhg.2014.02.004

PubMed ID: 26833328

Title: De Novo Loss-of-Function Mutations in USP9X Cause a Female-Specific Recognizable Syndrome with Developmental Delay and Congenital Malformations.

PubMed ID: 26833328

DOI: 10.1016/j.ajhg.2015.12.015

PubMed ID: 30914461

Title: Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X.

PubMed ID: 30914461

DOI: 10.1073/pnas.1815027116

Sequence Information:

  • Length: 2554
  • Mass: 290463
  • Checksum: 16B87B7FCC1428AF
  • Sequence:
    • MTATTRGSPV GGNDNQGQAP DGQSQPPLQQ NQTSSPDSSN ENSPATPPDE QGQGDAPPQL 
EDEEPAFPHT DLAKLDDMIN RPRWVVPVLP KGELEVLLEA AIDLSKKGLD VKSEACQRFF 
RDGLTISFTK ILTDEAVSGW KFEIHRCIIN NTHRLVELCV AKLSQDWFPL LELLAMALNP 
HCKFHIYNGT RPCESVSSSV QLPEDELFAR SPDPRSPKGW LVDLLNKFGT LNGFQILHDR 
FINGSALNVQ IIAALIKPFG QCYEFLTLHT VKKYFLPIIE MVPQFLENLT DEELKKEAKN 
EAKNDALSMI IKSLKNLASR VPGQEETVKN LEIFRLKMIL RLLQISSFNG KMNALNEVNK 
VISSVSYYTH RHGNPEEEEW LTAERMAEWI QQNNILSIVL RDSLHQPQYV EKLEKILRFV 
IKEKALTLQD LDNIWAAQAG KHEAIVKNVH DLLAKLAWDF SPEQLDHLFD CFKASWTNAS 
KKQREKLLEL IRRLAEDDKD GVMAHKVLNL LWNLAHSDDV PVDIMDLALS AHIKILDYSC 
SQDRDTQKIQ WIDRFIEELR TNDKWVIPAL KQIREICSLF GEAPQNLSQT QRSPHVFYRH 
DLINQLQHNH ALVTLVAENL ATYMESMRLY ARDHEDYDPQ TVRLGSRYSH VQEVQERLNF 
LRFLLKDGQL WLCAPQAKQI WKCLAENAVY LCDREACFKW YSKLMGDEPD LDPDINKDFF 
ESNVLQLDPS LLTENGMKCF ERFFKAVNCR EGKLVAKRRA YMMDDLELIG LDYLWRVVIQ 
SNDDIASRAI DLLKEIYTNL GPRLQVNQVV IHEDFIQSCF DRLKASYDTL CVLDGDKDSV 
NCARQEAVRM VRVLTVLREY INECDSDYHE ERTILPMSRA FRGKHLSFVV RFPNQGRQVD 
DLEVWSHTND TIGSVRRCIL NRIKANVAHT KIELFVGGEL IDPADDRKLI GQLNLKDKSL 
ITAKLTQISS NMPSSPDSSS DSSTGSPGNH GNHYSDGPNP EVESCLPGVI MSLHPRYISF 
LWQVADLGSS LNMPPLRDGA RVLMKLMPPD STTIEKLRAI CLDHAKLGES SLSPSLDSLF 
FGPSASQVLY LTEVVYALLM PAGAPLADDS SDFQFHFLKS GGLPLVLSML TRNNFLPNAD 
METRRGAYLN ALKIAKLLLT AIGYGHVRAV AEACQPGVEG VNPMTQINQV THDQAVVLQS 
ALQSIPNPSS ECMLRNVSVR LAQQISDEAS RYMPDICVIR AIQKIIWASG CGSLQLVFSP 
NEEITKIYEK TNAGNEPDLE DEQVCCEALE VMTLCFALIP TALDALSKEK AWQTFIIDLL 
LHCHSKTVRQ VAQEQFFLMC TRCCMGHRPL LFFITLLFTV LGSTARERAK HSGDYFTLLR 
HLLNYAYNSN INVPNAEVLL NNEIDWLKRI RDDVKRTGET GIEETILEGH LGVTKELLAF 
QTSEKKFHIG CEKGGANLIK ELIDDFIFPA SNVYLQYMRN GELPAEQAIP VCGSPPTINA 
GFELLVALAV GCVRNLKQIV DSLTEMYYIG TAITTCEALT EWEYLPPVGP RPPKGFVGLK 
NAGATCYMNS VIQQLYMIPS IRNGILAIEG TGSDVDDDMS GDEKQDNESN VDPRDDVFGY 
PQQFEDKPAL SKTEDRKEYN IGVLRHLQVI FGHLAASRLQ YYVPRGFWKQ FRLWGEPVNL 
REQHDALEFF NSLVDSLDEA LKALGHPAML SKVLGGSFAD QKICQGCPHR YECEESFTTL 
NVDIRNHQNL LDSLEQYVKG DLLEGANAYH CEKCNKKVDT VKRLLIKKLP PVLAIQLKRF 
DYDWERECAI KFNDYFEFPR ELDMEPYTVA GVAKLEGDNV NPESQLIQQS EQSESETAGS 
TKYRLVGVLV HSGQASGGHY YSYIIQRNGG DGERNRWYKF DDGDVTECKM DDDEEMKNQC 
FGGEYMGEVF DHMMKRMSYR RQKRWWNAYI LFYERMDTID QDDELIRYIS ELAITTRPHQ 
IIMPSAIERS VRKQNVQFMH NRMQYSMEYF QFMKKLLTCN GVYLNPPPGQ DHLLPEAEEI 
TMISIQLAAR FLFTTGFHTK KVVRGSASDW YDALCILLRH SKNVRFWFAH NVLFNVSNRF 
SEYLLECPSA EVRGAFAKLI VFIAHFSLQD GPCPSPFASP GPSSQAYDNL SLSDHLLRAV 
LNLLRREVSE HGRHLQQYFN LFVMYANLGV AEKTQLLKLS VPATFMLVSL DEGPGPPIKY 
QYAELGKLYS VVSQLIRCCN VSSRMQSSIN GNPPLPNPFG DPNLSQPIMP IQQNVADILF 
VRTSYVKKII EDCSNSEETV KLLRFCCWEN PQFSSTVLSE LLWQVAYSYT YELRPYLDLL 
LQILLIEDSW QTHRIHNALK GIPDDRDGLF DTIQRSKNHY QKRAYQCIKC MVALFSNCPV 
AYQILQGNGD LKRKWTWAVE WLGDELERRP YTGNPQYTYN NWSPPVQSNE TSNGYFLERS 
HSARMTLAKA CELCPEEEPD DQDAPDEHES PPPEDAPLYP HSPGSQYQQN NHVHGQPYTG 
PAAHHMNNPQ RTGQRAQENY EGSEEVSPPQ TKDQ

Genular Protein ID: 2967796661

Symbol: A0A994J6S4_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A994J6S4

Database IDs:

ARBA 3 CDD 1 CTD 1 EC 1 EMBL 2 Ensembl 2 GO 2 Gene3D 1 GeneTree 1 HGNC 1 InterPro 7 NCBI Taxonomy 1 PANTHER 2 PROSITE 4 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMR 1 SUPFAM 2

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

Sequence Information:

  • Length: 2559
  • Mass: 291027
  • Checksum: 3AB9D2E07C368009
  • Sequence:
    • MTATTRGSPV GGNDNQGQAP DGQSQPPLQQ NQTSSPDSSN ENSPATPPDE QGQGDAPPQL 
EDEEPAFPHT DLAKLDDMIN RPRWVVPVLP KGELEVLLEA AIDLSKKGLD VKSEACQRFF 
RDGLTISFTK ILTDEAVSGW KFEIHRCIIN NTHRLVELCV AKLSQDWFPL LELLAMALNP 
HCKFHIYNGT RPCESVSSSV QLPEDELFAR SPDPRSPKGW LVDLLNKFGT LNGFQILHDR 
FINGSALNVQ IIAALIKPFG QCYEFLTLHT VKKYFLPIIE MVPQFLENLT DEELKKEAKN 
EAKNDALSMI IKSLKNLASR VPGQEETVKN LEIFRLKMIL RLLQISSFNG KMNALNEVNK 
VISSVSYYTH RHGNPEEEEW LTAERMAEWI QQNNILSIVL RDSLHQPQYV EKLEKILRFV 
IKEKALTLQD LDNIWAAQAG KHEAIVKNVH DLLAKLAWDF SPEQLDHLFD CFKASWTNAS 
KKQREKLLEL IRRLAEDDKD GVMAHKVLNL LWNLAHSDDV PVDIMDLALS AHIKILDYSC 
SQDRDTQKIQ WIDRFIEELR TNDKWVIPAL KQIREICSLF GEAPQNLSSS RFSQTQRSPH 
VFYRHDLINQ LQHNHALVTL VAENLATYME SMRLYARDHE DYDPQTVRLG SRYSHVQEVQ 
ERLNFLRFLL KDGQLWLCAP QAKQIWKCLA ENAVYLCDRE ACFKWYSKLM GDEPDLDPDI 
NKDFFESNVL QLDPSLLTEN GMKCFERFFK AVNCREGKLV AKRRAYMMDD LELIGLDYLW 
RVVIQSNDDI ASRAIDLLKE IYTNLGPRLQ VNQVVIHEDF IQSCFDRLKA SYDTLCVLDG 
DKDSVNCARQ EAVRMVRVLT VLREYINECD SDYHEERTIL PMSRAFRGKH LSFVVRFPNQ 
GRQVDDLEVW SHTNDTIGSV RRCILNRIKA NVAHTKIELF VGGELIDPAD DRKLIGQLNL 
KDKSLITAKL TQISSNMPSS PDSSSDSSTG SPGNHGNHYS DGPNPEVESC LPGVIMSLHP 
RYISFLWQVA DLGSSLNMPP LRDGARVLMK LMPPDSTTIE KLRAICLDHA KLGESSLSPS 
LDSLFFGPSA SQVLYLTEVV YALLMPAGAP LADDSSDFQF HFLKSGGLPL VLSMLTRNNF 
LPNADMETRR GAYLNALKIA KLLLTAIGYG HVRAVAEACQ PGVEGVNPMT QINQVTHDQA 
VVLQSALQSI PNPSSECMLR NVSVRLAQQI SDEASRYMPD ICVIRAIQKI IWASGCGSLQ 
LVFSPNEEIT KIYEKTNAGN EPDLEDEQVC CEALEVMTLC FALIPTALDA LSKEKAWQTF 
IIDLLLHCHS KTVRQVAQEQ FFLMCTRCCM GHRPLLFFIT LLFTVLGSTA RERAKHSGDY 
FTLLRHLLNY AYNSNINVPN AEVLLNNEID WLKRIRDDVK RTGETGIEET ILEGHLGVTK 
ELLAFQTSEK KFHIGCEKGG ANLIKELIDD FIFPASNVYL QYMRNGELPA EQAIPVCGSP 
PTINAGFELL VALAVGCVRN LKQIVDSLTE MYYIGTAITT CEALTEWEYL PPVGPRPPKG 
FVGLKNAGAT CYMNSVIQQL YMIPSIRNGI LAIEGTGSDV DDDMSGDEKQ DNESNVDPRD 
DVFGYPQQFE DKPALSKTED RKEYNIGVLR HLQVIFGHLA ASRLQYYVPR GFWKQFRLWG 
EPVNLREQHD ALEFFNSLVD SLDEALKALG HPAMLSKVLG GSFADQKICQ GCPHRYECEE 
SFTTLNVDIR NHQNLLDSLE QYVKGDLLEG ANAYHCEKCN KKVDTVKRLL IKKLPPVLAI 
QLKRFDYDWE RECAIKFNDY FEFPRELDME PYTVAGVAKL EGDNVNPESQ LIQQSEQSES 
ETAGSTKYRL VGVLVHSGQA SGGHYYSYII QRNGGDGERN RWYKFDDGDV TECKMDDDEE 
MKNQCFGGEY MGEVFDHMMK RMSYRRQKRW WNAYILFYER MDTIDQDDEL IRYISELAIT 
TRPHQIIMPS AIERSVRKQN VQFMHNRMQY SMEYFQFMKK LLTCNGVYLN PPPGQDHLLP 
EAEEITMISI QLAARFLFTT GFHTKKVVRG SASDWYDALC ILLRHSKNVR FWFAHNVLFN 
VSNRFSEYLL ECPSAEVRGA FAKLIVFIAH FSLQDGPCPS PFASPGPSSQ AYDNLSLSDH 
LLRAVLNLLR REVSEHGRHL QQYFNLFVMY ANLGVAEKTQ LLKLSVPATF MLVSLDEGPG 
PPIKYQYAEL GKLYSVVSQL IRCCNVSSRM QSSINGNPPL PNPFGDPNLS QPIMPIQQNV 
ADILFVRTSY VKKIIEDCSN SEETVKLLRF CCWENPQFSS TVLSELLWQV AYSYTYELRP 
YLDLLLQILL IEDSWQTHRI HNALKGIPDD RDGLFDTIQR SKNHYQKRAY QCIKCMVALF 
SNCPVAYQIL QGNGDLKRKW TWAVEWLGDE LERRPYTGNP QYTYNNWSPP VQSNETSNGY 
FLERSHSARM TLAKACELCP EEEPDDQDAP DEHESPPPED APLYPHSPGS QYQQNNHVHG 
QPYTGPAAHH MNNPQRTGQR AQENYEGSEE VSPPQTKDQ

Genular Protein ID: 698146800

Symbol: Q86X58_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q86X58

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 InterPro 1 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 473
  • Mass: 53946
  • Checksum: AF3D5DCD2C82B217
  • Sequence:
    • KNVRFWFAHN VLFNVSNRFS EYLLECPSAE VRGAFAKLIV FIAHFSLQDG PCPSPFASPG 
PSSQAYDNLS LSDHLLRAVL NLLRREVSEH GRHLQQYFNL FVMYANLGVA EKTQLLKLSV 
PATFMLVSLD EGPGPPIKYQ YAELGKLYSV VSQLIRCCNV SSRMQSSING NPPLPNPFGD 
PNLSQPIMPI QQNVADILFV RTSYVKKIIE DCSNSEETVK LLRFCCWENP QFSSTVLSEL 
LWQVAYSYTY ELRPYLDLLL QILLIEDSWQ THRIHNALKG IPDDRDGLFD TIQRSKNHYQ 
KRAYQCIKCM VALFSNCPVA YQILQGNGDL KRKWTWAVEW LGDELERRPY TGNPQYTYNN 
WSPPVQSNET SNGYFLERSH SARMTLAKAC ELCPEEEPDD QDAPDEHESP PPEDAPLYPH 
SPGSQYQQNN HVHGQPYTGP AAHHMNNPQR TGQRAQENYE GSEEVSPPQT KDQ

Genular Protein ID: 4154436909

Symbol: Q6P468_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6P468

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 1 IntAct 1 InterPro 6 KEGG 1 MEROPS 1 MINT 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 2 SAM 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 918
  • Mass: 105886
  • Checksum: 4E50EF3E146352EB
  • Sequence:
    • KEYNIGVLRH LQVIFGHLAA SRLQYYVPRG FWKQFRLWGE PVNLREQHDA LEFFNSLVDS 
LDEALKALGH PAMLSKVLGG SFADQKICQG CPHRYECEES FTTLNVDIRN HQNLLDSLEQ 
YVKGDLLEGA NAYHCEKCNK KVDTVKRLLI KKLPPVLAIQ LKRFDYDWER ECAIKFNDYF 
EFPRELDMEP YTVAGVAKLE GDNVNPESQL IQQSEQSESE TAGSTKYRLV GVLVHSGQAS 
GGHYYSYIIQ RNGGDGERNR WYKFDDGDVT ECKMDDDEEM KNQCFGGEYM GEVFDHMMKR 
MSYRRQKRWW NAYILFYERM DTIDQDDELI RYISELAITT RPHQIIMPSA IERSVRKQNV 
QFMHNRMQYS MEYFQFMKKL LTCNGVYLNP PPGQDHLLPE AEEITMISIQ LAARFLFTTG 
FHTKKVVRGS ASDWYDALCI LLRHSKNVRF WFAHNVLFNV SNRFSEYLLE CPSAEVRGAF 
AKLIVFIAHF SLQDGPCPSP FASPGPSSQA YDNLSLSDHL LRAVLNLLRR EVSEHGRHLQ 
QYFNLFVMYA NLGVAEKTQL LKLSVPATFM LVSLDEGPGP PIKYQYAELG KLYSVVSQLI 
RCCNVSSRMQ SSINGNPPLP NPFGDPNLSQ PIMPIQQNVA DNLFVRTSYV KKIIEDCSNS 
EETVKLLRFC CWENPQFSST VLSELLWQVA YSYTYELRPY LDLLLQILLI EDSWQTHRIH 
NALKGIPDDR DGLFDTIQRS KNHYQKRAYQ CIKCMVALFS NCPVAYQILQ GNGDLKRKWT 
WAVEWLGDEL ERRPYTGNPQ YTYNNWSPPV QSNETSNGYF LERSHSARMT LAKACELCPE 
EEPDDQDAPD EHESPPPEDA PLYPHSPGSQ YQQNNHVHGQ PYTGPAAHHM NNPQRTGQRA 
QENYEGSEEV SPPQTKDQ

Genular Protein ID: 2022696911

Symbol: A0A994J4R6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A994J4R6

Database IDs:

ARBA 3 CDD 1 CTD 1 EC 1 EMBL 2 Ensembl 2 GO 2 Gene3D 1 GeneTree 1 HGNC 1 InterPro 7 NCBI Taxonomy 1 PANTHER 2 PROSITE 4 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMR 1 SUPFAM 2

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

Sequence Information:

  • Length: 2575
  • Mass: 292844
  • Checksum: 5E76536DFD000FEA
  • Sequence:
    • MTATTRGSPV GGNDNQGQAP DGQSQPPLQQ NQTSSPDSSN ENSPATPPDE QGQGDAPPQL 
EDEEPAFPHT DLAKLDDMIN RPRWVVPVLP KGELEVLLEA AIDLSKKGLD VKSEACQRFF 
RDGLTISFTK ILTDEAVSGW KFEIHRCIIN NTHRLVELCV AKLSQDWFPL LELLAMALNP 
HCKFHIYNGT RPCESVSSSV QLPEDELFAR SPDPRSPKGW LVDLLNKFGT LNGFQILHDR 
FINGSALNVQ IIAALIKPFG QCYEFLTLHT VKKYFLPIIE MVPQFLENLT DEELKKEAKN 
EAKNDALSMI IKSLKNLASR VPGQEETVKN LEIFRLKMIL RLLQISSFNG KMNALNEVNK 
VISSVSYYTH RHGNPEEEEW LTAERMAEWI QQNNILSIVL RDSLHQPQYV EKLEKILRFV 
IKEKALTLQD LDNIWAAQAG KHEAIVKNVH DLLAKLAWDF SPEQLDHLFD CFKASWTNAS 
KKQREKLLEL IRRLAEDDKD GVMAHKVLNL LWNLAHSDDV PVDIMDLALS AHIKILDYSC 
SQDRDTQKIQ WIDRFIEELR TNDKWVIPAL KQIREICSLF GEAPQNLSSS RFSQTQRSPH 
VFYRHDLINQ LQHNHALVTL VAENLATYME SMRLYARDHE DYDPQTVRLG SRYSHVQEVQ 
ERLNFLRFLL KDGQLWLCAP QAKQIWKCLA ENAVYLCDRE ACFKWYSKLM GDEPDLDPDI 
NKDFFESNVL QLDPSLLTEN GMKCFERFFK AVNCREGKLV AKRRAYMMDD LELIGLDYLW 
RVVIQSNDDI ASRAIDLLKE IYTNLGPRLQ VNQVVIHEDF IQSCFDRLKA SYDTLCVLDG 
DKDSVNCARQ EAVRMVRVLT VLREYINECD SDYHEERTIL PMSRAFRGKH LSFVVRFPNQ 
GRQVDDLEVW SHTNDTIGSV RRCILNRIKA NVAHTKIELF VGGELIDPAD DRKLIGQLNL 
KDKSLITAKL TQISSNMPSS PDSSSDSSTG SPGNHGNHYS DGPNPEVESC LPGVIMSLHP 
RYISFLWQVA DLGSSLNMPP LRDGARVLMK LMPPDSTTIE KLRAICLDHA KLGESSLSPS 
LDSLFFGPSA SQVLYLTEVV YALLMPAGAP LADDSSDFQF HFLKSGGLPL VLSMLTRNNF 
LPNADMETRR GAYLNALKIA KLLLTAIGYG HVRAVAEACQ PGVEGVNPMT QINQVTHDQA 
VVLQSALQSI PNPSSECMLR NVSVRLAQQI SDEASRYMPD ICVIRAIQKI IWASGCGSLQ 
LVFSPNEEIT KIYEKTNAGN EPDLEDEQVC CEALEVMTLC FALIPTALDA LSKEKAWQTF 
IIDLLLHCHS KTVRQVAQEQ FFLMCTRCCM GHRPLLFFIT LLFTVLGSTA RERAKHSGDY 
FTLLRHLLNY AYNSNINVPN AEVLLNNEID WLKRIRDDVK RTGETGIEET ILEGHLGVTK 
ELLAFQTSEK KFHIGCEKGG ANLIKELIDD FIFPASNVYL QYMRNGELPA EQAIPVCGSP 
PTINAGFELL VALAVGCVRN LKQIVDSLTE MYYIGTAITT CEALTEWEYL PPVGPRPPKG 
FVGLKNAGAT CYMNSVIQQL YMIPSIRNGI LAIEGTGSDV DDDMSGDEKQ DNESNVDPRD 
DVFGYPQQFE DKPALSKTED RKEYNIGVLR HLQVIFGHLA ASRLQYYVPR GFWKQFRLWG 
EPVNLREQHD ALEFFNSLVD SLDEALKALG HPAMLSKVLG GSFADQKICQ GCPHRYECEE 
SFTTLNVDIR NHQNLLDSLE QYVKGDLLEG ANAYHCEKCN KKVDTVKRLL IKKLPPVLAI 
QLKRFDYDWE RECAIKFNDY FEFPRELDME PYTVAGVAKL EGDNVNPESQ LIQQSEQSES 
ETAGSTKYRL VGVLVHSGQA SGGHYYSYII QRNGGDGERN RWYKFDDGDV TECKMDDDEE 
MKNQCFGGEY MGEVFDHMMK RMSYRRQKRW WNAYILFYER MDTIDQDDEL IRYISELAIT 
TRPHQIIMPS AIERSVRKQN VQFMHNRMQY SMEYFQFMKK LLTCNGVYLN PPPGQDHLLP 
EAEEITMISI QLAARFLFTT GFHTKKVVRG SASDWYDALC ILLRHSKNVR FWFAHNVLFN 
VSNRFSEYLL ECPSAEVRGA FAKLIVFIAH FSLQDGPCPS PFASPGPSSQ AYDNLSLSDH 
LLRAVLNLLR REVSEHGRHL QQYFNLFVMY ANLGVAEKTQ LLKLSVPATF MLVSLDEGPG 
PPIKYQYAEL GKLYSVVSQL IRCCNVSSRM QSSINGNPPL PNPFGDPNLS QPIMPIQQNV 
ADILFVRTSY VKKIIEDCSN SEETVKLLRF CCWENPQFSS TVLSELLWQV AYSYTYELRP 
YLDLLLQILL IEDSWQTHRI HNALKGIPDD RDGLFDTIQR SKNHYQKRAY QCIKCMVALF 
SNCPVAYQIL QGNGDLKRKW TWAVEWLGDE LERRPYTGNP QYTYNNWSPP VQSNETSNGY 
FLERSHSARM TLAKACELCP EEVKKATSVQ QIEMEESKEP DDQDAPDEHE SPPPEDAPLY 
PHSPGSQYQQ NNHVHGQPYT GPAAHHMNNP QRTGQRAQEN YEGSEEVSPP QTKDQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.