Details for: CARS1

Gene ID: 833

Symbol: CARS1

Ensembl ID: ENSG00000110619

Description: cysteinyl-tRNA synthetase 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 172.6829
    Cell Significance Index: -26.8600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 108.0651
    Cell Significance Index: -27.4100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 65.1804
    Cell Significance Index: -26.4800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 59.0705
    Cell Significance Index: -30.3900
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 47.2488
    Cell Significance Index: -31.7100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 27.8923
    Cell Significance Index: -26.6300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 23.1071
    Cell Significance Index: -28.4900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 7.3922
    Cell Significance Index: -29.1700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.0548
    Cell Significance Index: -15.4400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 6.7167
    Cell Significance Index: -20.6300
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 1.8118
    Cell Significance Index: 19.2500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.6393
    Cell Significance Index: 201.5700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.3977
    Cell Significance Index: 251.9600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.9965
    Cell Significance Index: 199.9000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.9499
    Cell Significance Index: 12.9600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8646
    Cell Significance Index: 94.0400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.8279
    Cell Significance Index: 22.5400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6353
    Cell Significance Index: 103.3300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.6058
    Cell Significance Index: 217.2800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.6047
    Cell Significance Index: 31.4100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.4604
    Cell Significance Index: 23.9800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4404
    Cell Significance Index: 194.7100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4163
    Cell Significance Index: 82.6100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.3921
    Cell Significance Index: 18.2800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3858
    Cell Significance Index: 11.1200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.3718
    Cell Significance Index: 10.9200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3039
    Cell Significance Index: 165.9500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.2913
    Cell Significance Index: 18.8000
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.2123
    Cell Significance Index: 3.2000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2080
    Cell Significance Index: 143.8600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2000
    Cell Significance Index: 5.5900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1893
    Cell Significance Index: 13.0900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.1812
    Cell Significance Index: 9.1600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1704
    Cell Significance Index: 23.4000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1603
    Cell Significance Index: 30.5000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1319
    Cell Significance Index: 15.5600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.1117
    Cell Significance Index: 4.9400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1102
    Cell Significance Index: 5.1800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1092
    Cell Significance Index: 4.9500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1058
    Cell Significance Index: 7.4800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1017
    Cell Significance Index: 13.1500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0765
    Cell Significance Index: 7.5700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0622
    Cell Significance Index: 10.6200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0555
    Cell Significance Index: 75.5300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0547
    Cell Significance Index: 49.3800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0420
    Cell Significance Index: 3.2200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0362
    Cell Significance Index: 66.6900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0312
    Cell Significance Index: 1.1800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0298
    Cell Significance Index: 2.2200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0139
    Cell Significance Index: 26.2600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0123
    Cell Significance Index: 18.9500
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.0092
    Cell Significance Index: 0.2900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0022
    Cell Significance Index: 0.0600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0046
    Cell Significance Index: -2.8900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0089
    Cell Significance Index: -6.7400
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: -0.0092
    Cell Significance Index: -0.0400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0137
    Cell Significance Index: -0.4800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0191
    Cell Significance Index: -8.6600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0197
    Cell Significance Index: -2.5300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0324
    Cell Significance Index: -23.7800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0373
    Cell Significance Index: -27.6100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0499
    Cell Significance Index: -28.1200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0523
    Cell Significance Index: -32.6800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0535
    Cell Significance Index: -5.4700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0674
    Cell Significance Index: -3.7800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0704
    Cell Significance Index: -1.5000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0725
    Cell Significance Index: -1.5700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0892
    Cell Significance Index: -25.6800
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -0.1046
    Cell Significance Index: -0.6500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1082
    Cell Significance Index: -15.7300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1157
    Cell Significance Index: -13.2600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1319
    Cell Significance Index: -3.7800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1373
    Cell Significance Index: -9.2300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1557
    Cell Significance Index: -32.7900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1603
    Cell Significance Index: -3.5100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1812
    Cell Significance Index: -5.1700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.1879
    Cell Significance Index: -1.7300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1941
    Cell Significance Index: -10.1900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2115
    Cell Significance Index: -13.3300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2425
    Cell Significance Index: -5.0300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.2618
    Cell Significance Index: -4.4100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2623
    Cell Significance Index: -27.3100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.2782
    Cell Significance Index: -5.4300
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.2854
    Cell Significance Index: -3.5400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2968
    Cell Significance Index: -6.3000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3128
    Cell Significance Index: -8.0400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3500
    Cell Significance Index: -27.7200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3550
    Cell Significance Index: -11.3700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3988
    Cell Significance Index: -12.7000
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.4039
    Cell Significance Index: -2.4400
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.4122
    Cell Significance Index: -5.1400
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.4137
    Cell Significance Index: -5.9500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4249
    Cell Significance Index: -13.9100
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.4304
    Cell Significance Index: -6.3500
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.4386
    Cell Significance Index: -9.1800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.4395
    Cell Significance Index: -8.6900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4607
    Cell Significance Index: -16.0100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.4703
    Cell Significance Index: -8.0600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4793
    Cell Significance Index: -12.8200
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.4794
    Cell Significance Index: -8.8600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** CARS1 exhibits several key characteristics that distinguish it from other tRNA synthetases. Its high specificity for cysteine residues allows it to accurately attach cysteine to its corresponding tRNA molecules, ensuring the correct incorporation of cysteine into proteins. Additionally, CARS1 is involved in the regulation of protein synthesis and modification, which is critical for maintaining cellular homeostasis. Its high expression levels in various cell types suggest that CARS1 plays a multifaceted role in cellular processes, including development, growth, and immune response. **Pathways and Functions** CARS1 is involved in several biological pathways, including: 1. **Translation**: CARS1 is essential for the incorporation of cysteine residues into proteins during translation. By accurately attaching cysteine to its corresponding tRNA molecules, CARS1 ensures the proper folding and function of cysteine-containing proteins. 2. **Metabolism of proteins**: CARS1 is involved in the regulation of protein synthesis and modification, which is critical for maintaining cellular homeostasis. Dysregulation of CARS1 has been linked to various diseases, including cancer and neurodegenerative disorders. 3. **Signaling pathways**: CARS1 is involved in the regulation of signaling pathways, including those mediated by growth factor receptors and second messengers. Its dysregulation has been linked to various diseases, including cancer and cardiovascular disease. **Clinical Significance** CARS1 has significant clinical implications due to its involvement in various diseases. Some of the key clinical implications of CARS1 dysregulation include: 1. **Cancer**: CARS1 is overexpressed in certain types of cancer, including breast and lung cancer. Its dysregulation has been linked to tumor progression and metastasis. 2. **Neurodegenerative disorders**: CARS1 is involved in the regulation of protein synthesis and modification in neurons. Its dysregulation has been linked to various neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease. 3. **Cardiovascular disease**: CARS1 is involved in the regulation of signaling pathways in cardiovascular cells. Its dysregulation has been linked to various cardiovascular diseases, including atherosclerosis and hypertension. In conclusion, CARS1 is a critical enzyme involved in the post-translational modification of cysteine-containing proteins. Its dysregulation has significant clinical implications, including its involvement in cancer, neurodegenerative disorders, and cardiovascular disease. Further research is needed to fully understand the mechanisms by which CARS1 regulates protein synthesis and modification, and to develop therapeutic strategies to target CARS1 in disease prevention and treatment.

Genular Protein ID: 992429381

Symbol: SYCC_HUMAN

Name: Cysteine--tRNA ligase, cytoplasmic

UniProtKB Accession Codes:

P49589 Q53XI8 Q5HYE4 Q9HD24 Q9HD25

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChEBI 15 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 DrugCentral 1 EC 1 EMBL 10 Ensembl 6 ExpressionAtlas 1 GO 9 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HAMAP 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 2 RefSeq 3 Rhea 4 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 2 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7987009

Title: Nucleotide and deduced amino acid sequence of human cysteinyl-tRNA synthetase.

PubMed ID: 7987009

DOI: 10.3109/10425179409020847

PubMed ID: 11347887

Title: Isolation of two cDNAs encoding functional human cytoplasmic cysteinyl-tRNA synthetase.

PubMed ID: 11347887

DOI: 10.1515/bc.2001.049

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12112524

Title: Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor.

PubMed ID: 12112524

DOI: 10.1002/gcc.10033

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 30824121

Title: Cysteinyl-tRNA synthetase mutations cause a multi-system, recessive disease that includes microcephaly, developmental delay, and brittle hair and nails.

PubMed ID: 30824121

DOI: 10.1016/j.ajhg.2019.01.006

Sequence Information:

  • Length: 748
  • Mass: 85473
  • Checksum: D0B7A29EC03AA87F
  • Sequence:
    • MADSSGQQGK GRRVQPQWSP PAGTQPCRLH LYNSLTRNKE VFIPQDGKKV TWYCCGPTVY 
DASHMGHARS YISFDILRRV LKDYFKFDVF YCMNITDIDD KIIKRARQNH LFEQYREKRP 
EAAQLLEDVQ AALKPFSVKL NETTDPDKKQ MLERIQHAVQ LATEPLEKAV QSRLTGEEVN 
SCVEVLLEEA KDLLSDWLDS TLGCDVTDNS IFSKLPKFWE GDFHRDMEAL NVLPPDVLTR 
VSEYVPEIVN FVQKIVDNGY GYVSNGSVYF DTAKFASSEK HSYGKLVPEA VGDQKALQEG 
EGDLSISADR LSEKRSPNDF ALWKASKPGE PSWPCPWGKG RPGWHIECSA MAGTLLGASM 
DIHGGGFDLR FPHHDNELAQ SEAYFENDCW VRYFLHTGHL TIAGCKMSKS LKNFITIKDA 
LKKHSARQLR LAFLMHSWKD TLDYSSNTME SALQYEKFLN EFFLNVKDIL RAPVDITGQF 
EKWGEEEAEL NKNFYDKKTA IHKALCDNVD TRTVMEEMRA LVSQCNLYMA ARKAVRKRPN 
QALLENIALY LTHMLKIFGA VEEDSSLGFP VGGPGTSLSL EATVMPYLQV LSEFREGVRK 
IAREQKVPEI LQLSDALRDN ILPELGVRFE DHEGLPTVVK LVDRNTLLKE REEKRRVEEE 
KRKKKEEAAR RKQEQEAAKL AKMKIPPSEM FLSETDKYSK FDENGLPTHD MEGKELSKGQ 
AKKLKKLFEA QEKLYKEYLQ MAQNGSFQ

Genular Protein ID: 2017347110

Symbol: B4DPV7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DPV7

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 7 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 5 Gene3D 2 HAMAP 1 InterPro 6 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 1 Pfam 2 RefSeq 1 Rhea 4 SAM 1 SUPFAM 3

Sequence Information:

  • Length: 809
  • Mass: 92019
  • Checksum: C05376F3F04FD266
  • Sequence:
    • MADSSGQQAP DYRSILSISD EAARAQALNE HLSTRSYVQG YSLSQADVDA FRQLSAPPAD 
PQLFHVARWF RHIEALLGSP CGKGQPCRLQ ASKGRRVQPQ WSPPAGTQPC RLHLYNSLTR 
NKEVFIPQDG KKVTWYCCGP TVYDASHMGH ARSYISFDIL RRVLKDYFKF DVFYCMNITD 
IDDKIIKRAR QNHLFEQYRE KRPEAAQLLE DVQAALKPFS VKLNETTDPD KKQMLERIQH 
AVQLATEPLE KAVQSRLTGE EVNSCVEVLL EEAKDLLSDW LDSTFGCDVT DNSIFSKLPK 
FWEGDFHRDM EALNVLPPDV LTRVSEYVPE IVNFVQKIVD NGYGYVSNGS VYFDTAKFAS 
SEKHSYGKLV PEAVGDQKAL QEGEGDLSIS ADRLSEKRSP NDFALWKASK PGEPSWPCPW 
GKGRPGWHIE CSAMAGTLLG ASMDIHGGGF DLRFPHHDNE LAQSEAYFEN DCWVRYFLHT 
GHLTIAGCKM SKSLKNFITI KDALKKHSAR QLRLAFLMHS WKDTLDYSSN TMESALQYEK 
FLNEFFLNVK DILRAPVDIT GQFEKWGEEE AELNKNFYDK KTAIHKALCD NVDTRTVMEE 
MRASVSQCNL YMAARKAVRK RPNQALLENI ALYLTHMLKI FGAVEEDSSL GFPVGGPGTS 
LSLEATVMPY LQVLSEFREG VRKIAREQKV PEILQLSDAL RDNILPELGV RFEDHEGLPT 
VVKLVDRNTL LKEREEKRRV EEEKRKKKEE AARRKQEQEA AKLAKMKIPP SEMFLSETDK 
YSKFDENVSM VCPHMTWRAK SSAKGKPRS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.