Details for: UXT
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 304.0273
Cell Significance Index: -47.2900 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 175.6534
Cell Significance Index: -72.3600 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 162.0525
Cell Significance Index: -65.8400 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 145.7460
Cell Significance Index: -68.8100 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 138.9620
Cell Significance Index: -71.4800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 126.9893
Cell Significance Index: -32.2100 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 102.8431
Cell Significance Index: -69.0100 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 69.3695
Cell Significance Index: -66.2300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 50.9102
Cell Significance Index: -62.7700 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 17.9296
Cell Significance Index: -55.0700 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 17.3389
Cell Significance Index: -68.4200 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 16.3353
Cell Significance Index: -43.7600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 9.3713
Cell Significance Index: -20.5100 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 6.2622
Cell Significance Index: 167.5100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 3.9419
Cell Significance Index: 183.7900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 3.2626
Cell Significance Index: 210.4900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 2.7528
Cell Significance Index: 129.3800 - Cell Name: lactocyte (CL0002325)
Fold Change: 2.6821
Cell Significance Index: 346.5100 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 2.5943
Cell Significance Index: 155.7500 - Cell Name: peg cell (CL4033014)
Fold Change: 2.5897
Cell Significance Index: 59.8300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.5059
Cell Significance Index: 344.1300 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 2.4308
Cell Significance Index: 71.3900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 2.3877
Cell Significance Index: 281.5800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 2.3197
Cell Significance Index: 164.0600 - Cell Name: granulosa cell (CL0000501)
Fold Change: 2.2974
Cell Significance Index: 60.4100 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 2.2763
Cell Significance Index: 61.9600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 2.1122
Cell Significance Index: 259.7200 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.0178
Cell Significance Index: 1101.9700 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.9563
Cell Significance Index: 864.9400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.8890
Cell Significance Index: 340.5300 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 1.7306
Cell Significance Index: 19.6600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.7298
Cell Significance Index: 128.9200 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 1.2499
Cell Significance Index: 13.2800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.1608
Cell Significance Index: 60.3000 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.1386
Cell Significance Index: 32.6400 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 1.0818
Cell Significance Index: 16.2100 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 1.0364
Cell Significance Index: 18.3200 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.9971
Cell Significance Index: 12.7700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.8949
Cell Significance Index: 152.8100 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.8792
Cell Significance Index: 16.2500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.8313
Cell Significance Index: 750.5700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.8189
Cell Significance Index: 23.6000 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.7279
Cell Significance Index: 93.3100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.7149
Cell Significance Index: 70.7200 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.6814
Cell Significance Index: 6.2800 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.5738
Cell Significance Index: 12.0100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.3995
Cell Significance Index: 18.1100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3843
Cell Significance Index: 73.1300 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.3293
Cell Significance Index: 3.5800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.2322
Cell Significance Index: 6.2000 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.2092
Cell Significance Index: 1.6700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.1353
Cell Significance Index: 102.4100 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.1209
Cell Significance Index: 4.2000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.0347
Cell Significance Index: 1.1100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0328
Cell Significance Index: 24.0500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0060
Cell Significance Index: -4.4400 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0134
Cell Significance Index: -1.3700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0219
Cell Significance Index: -41.3100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0368
Cell Significance Index: -67.8800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0439
Cell Significance Index: -27.4400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0439
Cell Significance Index: -67.5900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0562
Cell Significance Index: -76.3700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0757
Cell Significance Index: -15.0300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0765
Cell Significance Index: -43.1400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0872
Cell Significance Index: -31.2800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0911
Cell Significance Index: -57.8800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.1336
Cell Significance Index: -26.8000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.1402
Cell Significance Index: -63.6100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1440
Cell Significance Index: -30.3200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1917
Cell Significance Index: -21.9700 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1938
Cell Significance Index: -4.9500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2003
Cell Significance Index: -57.6400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.2755
Cell Significance Index: -7.7000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.3434
Cell Significance Index: -40.0200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.4121
Cell Significance Index: -59.9100 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -0.4672
Cell Significance Index: -2.8800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.4838
Cell Significance Index: -30.4900 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.5000
Cell Significance Index: -57.0700 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.5358
Cell Significance Index: -11.4100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.5420
Cell Significance Index: -9.0700 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -0.5580
Cell Significance Index: -9.6200 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.5970
Cell Significance Index: -6.1800 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5979
Cell Significance Index: -47.3500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.6449
Cell Significance Index: -67.1500 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.6689
Cell Significance Index: -16.7200 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.6960
Cell Significance Index: -42.7800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.7213
Cell Significance Index: -37.8700 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.7256
Cell Significance Index: -9.9000 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.7526
Cell Significance Index: -39.2000 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.7825
Cell Significance Index: -60.0500 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.7910
Cell Significance Index: -21.2000 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.7975
Cell Significance Index: -44.7500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.9491
Cell Significance Index: -58.1900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.9845
Cell Significance Index: -66.2000 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -1.2066
Cell Significance Index: -26.1400 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -1.2936
Cell Significance Index: -53.0100 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -1.2962
Cell Significance Index: -38.1800 - Cell Name: perivascular cell (CL4033054)
Fold Change: -1.3385
Cell Significance Index: -6.1800 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -1.3440
Cell Significance Index: -8.1200 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -1.4149
Cell Significance Index: -71.5000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4273698242
Symbol: UXT_HUMAN
Name: Protein UXT
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10087202
Title: Cloning and characterization of UXT, a novel gene in human Xp11, which is widely and abundantly expressed in tumor tissue.
PubMed ID: 10087202
PubMed ID: 11854421
Title: Identification and characterization of ART-27, a novel coactivator for the androgen receptor N terminus.
PubMed ID: 11854421
PubMed ID: 17635584
Title: UXT interacts with the transcriptional repressor protein EVI1 and suppresses cell transformation.
PubMed ID: 17635584
PubMed ID: 11042152
Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.
PubMed ID: 11042152
DOI: 10.1101/gr.140200
PubMed ID: 21307340
Title: UXT-V1 protects cells against TNF-induced apoptosis through modulating complex II formation.
PubMed ID: 21307340
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15772651
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11827465
Title: Sequence analysis of LRPPRC and its SEC1 domain interaction partners suggests roles in cytoskeletal organization, vesicular trafficking, nucleocytosolic shuttling, and chromosome activity.
PubMed ID: 11827465
PubMed ID: 16221885
Title: UXT is a novel centrosomal protein essential for cell viability.
PubMed ID: 16221885
PubMed ID: 17554592
Title: UXT (Ubiquitously Expressed Transcript) causes mitochondrial aggregation.
PubMed ID: 17554592
PubMed ID: 17620405
Title: UXT is a novel and essential cofactor in the NF-kappaB transcriptional enhanceosome.
PubMed ID: 17620405
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21730289
Title: Regulation of androgen receptor-mediated transcription by RPB5 binding protein URI/RMP.
PubMed ID: 21730289
DOI: 10.1128/mcb.05429-11
PubMed ID: 28106301
Title: UXT is a LOX-PP interacting protein that modulates estrogen receptor alpha activity in breast cancer Cells.
PubMed ID: 28106301
DOI: 10.1002/jcb.25893
PubMed ID: 31738558
Title: Upstream ORF-Encoded ASDURF Is a Novel Prefoldin-like Subunit of the PAQosome.
PubMed ID: 31738558
PubMed ID: 33010352
Title: The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-kappaB signaling pathway.
PubMed ID: 33010352
Sequence Information:
- Length: 157
- Mass: 18246
- Checksum: 94CE14C462DEE308
- Sequence:
MATPPKRRAV EATGEKVLRY ETFISDVLQR DLRKVLDHRD KVYEQLAKYL QLRNVIERLQ EAKHSELYMQ VDLGCNFFVD TVVPDTSRIY VALGYGFFLE LTLAEALKFI DRKSSLLTEL SNSLTKDSMN IKAHIHMLLE GLRELQGLQN FPEKPHH
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.