Details for: APOL1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 97.5922
Cell Significance Index: -15.1800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 55.5701
Cell Significance Index: -14.1000 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 32.4492
Cell Significance Index: -15.3200 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 12.5146
Cell Significance Index: -15.4300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 6.2059
Cell Significance Index: 322.3800 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 5.1011
Cell Significance Index: -13.6700 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 3.8976
Cell Significance Index: -15.3800 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 2.5450
Cell Significance Index: -5.5700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 1.9567
Cell Significance Index: 228.0300 - Cell Name: peg cell (CL4033014)
Fold Change: 1.2790
Cell Significance Index: 29.5500 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 1.1849
Cell Significance Index: 7.7300 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.0470
Cell Significance Index: 14.2900 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 1.0083
Cell Significance Index: 9.2900 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.9231
Cell Significance Index: 25.1300 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.9049
Cell Significance Index: 10.2800 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.7738
Cell Significance Index: 13.0400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.7694
Cell Significance Index: 694.7300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.6252
Cell Significance Index: 13.3200 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.5746
Cell Significance Index: 8.8900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.5606
Cell Significance Index: 68.9400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.5492
Cell Significance Index: 32.9700 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.5407
Cell Significance Index: 7.9800 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.5384
Cell Significance Index: 15.4400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.5163
Cell Significance Index: 56.1600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.4715
Cell Significance Index: 85.0100 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.4297
Cell Significance Index: 69.8900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.4297
Cell Significance Index: 9.3100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: 0.3919
Cell Significance Index: 44.7400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.3773
Cell Significance Index: 37.3200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.3072
Cell Significance Index: 21.2500 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3046
Cell Significance Index: 166.3500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.2822
Cell Significance Index: 38.7500 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.2332
Cell Significance Index: 29.8900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.1545
Cell Significance Index: 96.4800 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.1276
Cell Significance Index: 2.4900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0944
Cell Significance Index: 2.3600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0718
Cell Significance Index: 13.6700 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.0702
Cell Significance Index: 1.2400 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.0657
Cell Significance Index: 0.9500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0583
Cell Significance Index: 1.6800 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.0133
Cell Significance Index: 0.6700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0123
Cell Significance Index: 2.4400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.0060
Cell Significance Index: 0.2800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0018
Cell Significance Index: 0.7900 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0013
Cell Significance Index: -0.1700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0043
Cell Significance Index: -8.1900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0053
Cell Significance Index: -3.9500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0054
Cell Significance Index: -4.0500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0078
Cell Significance Index: -0.8000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0093
Cell Significance Index: -17.2000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0117
Cell Significance Index: -17.9900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0122
Cell Significance Index: -6.8900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0129
Cell Significance Index: -17.5600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0156
Cell Significance Index: -11.4400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0192
Cell Significance Index: -12.2200 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0192
Cell Significance Index: -1.4300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0204
Cell Significance Index: -2.9700 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0270
Cell Significance Index: -0.9500 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.0272
Cell Significance Index: -0.8000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0324
Cell Significance Index: -14.7100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0337
Cell Significance Index: -5.7500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0376
Cell Significance Index: -7.9300 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0386
Cell Significance Index: -13.8400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0409
Cell Significance Index: -1.8600 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0442
Cell Significance Index: -12.7200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0494
Cell Significance Index: -1.3200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0539
Cell Significance Index: -10.8200 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.0624
Cell Significance Index: -0.9400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0787
Cell Significance Index: -2.2000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0841
Cell Significance Index: -3.9200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0854
Cell Significance Index: -9.7800 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.1039
Cell Significance Index: -1.9200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1128
Cell Significance Index: -13.3000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1224
Cell Significance Index: -8.6600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1488
Cell Significance Index: -15.4900 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.1501
Cell Significance Index: -6.1500 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: -0.1600
Cell Significance Index: -2.2200 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1708
Cell Significance Index: -11.0200 - Cell Name: taste receptor cell (CL0000209)
Fold Change: -0.1725
Cell Significance Index: -2.0100 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1809
Cell Significance Index: -11.0900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1862
Cell Significance Index: -14.2900 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.1935
Cell Significance Index: -2.9000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.2026
Cell Significance Index: -6.4900 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.2219
Cell Significance Index: -5.6700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.2278
Cell Significance Index: -15.3200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.2406
Cell Significance Index: -15.1700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.2560
Cell Significance Index: -15.7400 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.2692
Cell Significance Index: -7.2000 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.2901
Cell Significance Index: -16.2800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2945
Cell Significance Index: -15.4600 - Cell Name: proerythroblast (CL0000547)
Fold Change: -0.3440
Cell Significance Index: -4.9300 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.3514
Cell Significance Index: -10.3500 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.3714
Cell Significance Index: -13.6400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.3715
Cell Significance Index: -9.5500 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: -0.3943
Cell Significance Index: -4.0800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.3986
Cell Significance Index: -17.6300 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.4019
Cell Significance Index: -6.7600 - Cell Name: pulmonary capillary endothelial cell (CL4028001)
Fold Change: -0.4053
Cell Significance Index: -5.5500 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.4098
Cell Significance Index: -14.2400 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.4146
Cell Significance Index: -14.5300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2070373698
Symbol: APOL1_HUMAN
Name: Apolipoprotein L1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9325276
Title: Apolipoprotein L, a new human high density lipoprotein apolipoprotein expressed by the pancreas. Identification, cloning, characterization, and plasma distribution of apolipoprotein L.
PubMed ID: 9325276
PubMed ID: 11290834
Title: Apolipoprotein L gene family: tissue-specific expression, splicing, promoter regions; discovery of a new gene.
PubMed ID: 11290834
PubMed ID: 11374903
Title: The human apolipoprotein L gene cluster: identification, classification, and sites of distribution.
PubMed ID: 11374903
PubMed ID: 11944986
Title: The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue.
PubMed ID: 11944986
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 10591208
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 16335952
Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.
PubMed ID: 16335952
DOI: 10.1021/pr0502065
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 26091039
Title: A single kinase generates the majority of the secreted phosphoproteome.
PubMed ID: 26091039
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
PubMed ID: 20635188
Title: Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene.
PubMed ID: 20635188
PubMed ID: 20647424
Title: Association of trypanolytic ApoL1 variants with kidney disease in African Americans.
PubMed ID: 20647424
Sequence Information:
- Length: 398
- Mass: 43974
- Checksum: BD1A8F1D7C5A889F
- Sequence:
MEGAALLRVS VLCIWMSALF LGVGVRAEEA GARVQQNVPS GTDTGDPQSK PLGDWAAGTM DPESSIFIED AIKYFKEKVS TQNLLLLLTD NEAWNGFVAA AELPRNEADE LRKALDNLAR QMIMKDKNWH DKGQQYRNWF LKEFPRLKSE LEDNIRRLRA LADGVQKVHK GTTIANVVSG SLSISSGILT LVGMGLAPFT EGGSLVLLEP GMELGITAAL TGITSSTMDY GKKWWTQAQA HDLVIKSLDK LKEVREFLGE NISNFLSLAG NTYQLTRGIG KDIRALRRAR ANLQSVPHAS ASRPRVTEPI SAESGEQVER VNEPSILEMS RGVKLTDVAP VSFFLVLDVV YLVYESKHLH EGAKSETAEE LKKVAQELEE KLNILNNNYK ILQADQEL
Genular Protein ID: 2919159815
Symbol: B1AH95_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10591208
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 18477386
Title: Finishing the finished human chromosome 22 sequence.
PubMed ID: 18477386
Sequence Information:
- Length: 141
- Mass: 14954
- Checksum: 7E19BDB78F832AA0
- Sequence:
MEGAALLRVS VLCIWMSALF LGVGVRAEEA GARVQQNVPS GTDTGDPQSK PLGDWAAGTM DPGPAGSRGD SGEPCTLRPA CRGQRQHGGA SRISAEGPAP MPRRRTPSTA HLRVPKTSRR NLLCMRAVSL LRMPLSISRK K
Genular Protein ID: 3139766536
Symbol: Q2KHQ6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 398
- Mass: 43927
- Checksum: 6FDC5702C6C8EB36
- Sequence:
MEGAALLRVS VLCIWMSALF LGVGVRAEEA GARVQQNVPS GTDTGDPQSK PLGDWAAGTM DPESSIFIED AIKYFKEKVS TQNLLLLLTD NEAWNGFVAA AELPRNEADE LRKALDNLAR QMIMKDKNWH DKGQQYRNWF LKEFPRLKSK LEDNIRRLRA LADGVQKVHK GTTIANVVSG SLSISSGILT LVGMGLAPFT EGGSLVLLEP GMELGITAAL TGITSSTIDY GKKWWTQAQA HDLVIKSLDK LKEVKEFLGE NISNFLSLAG NTYQLTRGIG KDIRALRRAR ANLQSVPHAS ASRPRVTEPI SAESGEQVER VNEPSILEMS RGVKLTDVAP VSFFLVLDVV YLVYESKHLH EGAKSETAEE LKKVAQELEE KLNILNNNYK ILQADQEL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.