Details for: PRKRA

Gene ID: 8575

Symbol: PRKRA

Ensembl ID: ENSG00000180228

Description: protein activator of interferon induced protein kinase EIF2AK2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 263.0746
    Cell Significance Index: -40.9200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 142.0104
    Cell Significance Index: -36.0200
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 115.5001
    Cell Significance Index: -47.5800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 94.1281
    Cell Significance Index: -44.4400
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 81.6509
    Cell Significance Index: -42.0000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 34.9648
    Cell Significance Index: -43.1100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 13.1101
    Cell Significance Index: -35.1200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 11.0921
    Cell Significance Index: -43.7700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 9.0576
    Cell Significance Index: -27.8200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 8.6860
    Cell Significance Index: -19.0100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.9968
    Cell Significance Index: 125.8500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.9697
    Cell Significance Index: 566.7500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.4347
    Cell Significance Index: 49.8600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.1996
    Cell Significance Index: 195.1000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.1780
    Cell Significance Index: 233.7700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.1036
    Cell Significance Index: 221.3800
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 1.0822
    Cell Significance Index: 9.0900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.0452
    Cell Significance Index: 28.4500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 1.0142
    Cell Significance Index: 12.0900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.8640
    Cell Significance Index: 22.7200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.8421
    Cell Significance Index: 11.4900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.8385
    Cell Significance Index: 115.1500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.7366
    Cell Significance Index: 54.9000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.6845
    Cell Significance Index: 38.4100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.6137
    Cell Significance Index: 335.1500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.6124
    Cell Significance Index: 72.2200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.5951
    Cell Significance Index: 76.8900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.5471
    Cell Significance Index: 67.2800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.5298
    Cell Significance Index: 95.5000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.5233
    Cell Significance Index: 32.1700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.5205
    Cell Significance Index: 24.2700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.5050
    Cell Significance Index: 23.7400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4991
    Cell Significance Index: 220.6500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4956
    Cell Significance Index: 177.7500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.4766
    Cell Significance Index: 33.7100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.3759
    Cell Significance Index: 24.2500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.3727
    Cell Significance Index: 47.7800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3151
    Cell Significance Index: 284.4900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3031
    Cell Significance Index: 57.6900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.2680
    Cell Significance Index: 14.0700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2348
    Cell Significance Index: 162.3700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2272
    Cell Significance Index: 15.7100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2118
    Cell Significance Index: 36.1700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1639
    Cell Significance Index: 7.4300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1411
    Cell Significance Index: 7.3300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0777
    Cell Significance Index: 7.6900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0618
    Cell Significance Index: 116.3700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0497
    Cell Significance Index: 31.5600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0487
    Cell Significance Index: 1.3600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0476
    Cell Significance Index: 3.6500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0127
    Cell Significance Index: 19.6300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.0121
    Cell Significance Index: 0.2900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0119
    Cell Significance Index: 21.9000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0094
    Cell Significance Index: 4.2600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0018
    Cell Significance Index: 1.3400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0026
    Cell Significance Index: -0.0700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0078
    Cell Significance Index: -0.1300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0081
    Cell Significance Index: -6.0200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0139
    Cell Significance Index: -0.4900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0159
    Cell Significance Index: -9.9600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0170
    Cell Significance Index: -12.4300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0189
    Cell Significance Index: -25.7000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0240
    Cell Significance Index: -1.0600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0258
    Cell Significance Index: -0.5400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0360
    Cell Significance Index: -0.7800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0461
    Cell Significance Index: -0.7900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0534
    Cell Significance Index: -30.1100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0593
    Cell Significance Index: -6.0600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1082
    Cell Significance Index: -22.7900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1154
    Cell Significance Index: -4.3700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1277
    Cell Significance Index: -14.6300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1372
    Cell Significance Index: -15.9900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1420
    Cell Significance Index: -20.6400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1443
    Cell Significance Index: -9.7000
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.1515
    Cell Significance Index: -1.2100
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.1555
    Cell Significance Index: -1.6900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2498
    Cell Significance Index: -8.0000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2591
    Cell Significance Index: -29.5800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2858
    Cell Significance Index: -7.3000
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.3101
    Cell Significance Index: -2.3900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.3202
    Cell Significance Index: -6.2500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3377
    Cell Significance Index: -35.1600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4324
    Cell Significance Index: -34.2500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.4690
    Cell Significance Index: -13.4500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.5247
    Cell Significance Index: -14.0600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.5690
    Cell Significance Index: -12.4600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.5816
    Cell Significance Index: -17.0800
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.5938
    Cell Significance Index: -6.1500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.6132
    Cell Significance Index: -18.0600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.6423
    Cell Significance Index: -18.3300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.6559
    Cell Significance Index: -17.5500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.6590
    Cell Significance Index: -14.0400
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.6697
    Cell Significance Index: -16.3400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7100
    Cell Significance Index: -43.5300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.7219
    Cell Significance Index: -12.1600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.7331
    Cell Significance Index: -15.5600
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.7886
    Cell Significance Index: -13.9400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.8265
    Cell Significance Index: -21.2500
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.8406
    Cell Significance Index: -19.4200
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.8517
    Cell Significance Index: -18.2100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** PRKRA is a protein activator that specifically binds to and activates EIF2AK2, a key component of the interferon signaling pathway. The EIF2AK2-PRKRA complex is essential for the activation of ISGs, which are transcription factors that regulate the expression of genes involved in the innate immune response. PRKRA is characterized by its ability to regulate the activity of EIF2AK2, as well as its involvement in various cellular processes, including: * Antiviral defense: PRKRA is essential for the activation of ISGs, which are critical for the defense against viral infections. * Cell proliferation: PRKRA has been shown to regulate cell proliferation in various cell types, including epithelial cells and immune cells. * Apoptosis: PRKRA may also play a role in regulating apoptosis, a process essential for eliminating infected cells. * MicroRNA biogenesis: PRKRA has been implicated in the regulation of microRNA (miRNA) biogenesis, a process critical for the regulation of gene expression. **Pathways and Functions** PRKRA is involved in several key pathways, including: * **Interferon signaling pathway**: PRKRA is essential for the activation of ISGs, which are transcription factors that regulate the expression of genes involved in the innate immune response. * **Antiviral response**: PRKRA plays a critical role in the defense against viral infections by regulating the expression of ISGs. * **Cell proliferation**: PRKRA regulates cell proliferation in various cell types, including epithelial cells and immune cells. * **Apoptosis**: PRKRA may also play a role in regulating apoptosis, a process essential for eliminating infected cells. * **MicroRNA biogenesis**: PRKRA has been implicated in the regulation of miRNA biogenesis, a process critical for the regulation of gene expression. **Clinical Significance** Dysregulation of PRKRA has been implicated in various diseases, including: * **Viral infections**: PRKRA is essential for the defense against viral infections, and dysregulation of PRKRA may contribute to the development of viral infections. * **Cancer**: PRKRA has been implicated in the regulation of cell proliferation and apoptosis, and dysregulation of PRKRA may contribute to the development of cancer. * **Autoimmune diseases**: PRKRA may also play a role in the regulation of immune responses, and dysregulation of PRKRA may contribute to the development of autoimmune diseases. * **Neurological disorders**: PRKRA has been implicated in the regulation of neuronal function, and dysregulation of PRKRA may contribute to the development of neurological disorders. In conclusion, PRKRA is a critical regulator of the innate immune response, and dysregulation of PRKRA may contribute to the development of various diseases. Further research is needed to fully understand the role of PRKRA in human disease and to identify potential therapeutic targets for the treatment of PRKRA-related disorders.

Genular Protein ID: 1261461696

Symbol: PRKRA_HUMAN

Name: Interferon-inducible double-stranded RNA-dependent protein kinase activator A

UniProtKB Accession Codes:

O75569 A8K3I6 Q53G24 Q6X7T5 Q8NDK4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 3 CPTAC 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DNASU 1 DisGeNET 1 EMBL 12 EMDB 3 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 32 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 3 RefSeq 3 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9687506

Title: PACT, a protein activator of the interferon-induced protein kinase, PKR.

PubMed ID: 9687506

DOI: 10.1093/emboj/17.15.4379

PubMed ID: 10336432

Title: RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling.

PubMed ID: 10336432

DOI: 10.1074/jbc.274.22.15427

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11238927

Title: Modular structure of PACT: distinct domains for binding and activating PKR.

PubMed ID: 11238927

DOI: 10.1128/mcb.21.6.1908-1920.2001

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16424907

Title: The role of PACT in the RNA silencing pathway.

PubMed ID: 16424907

DOI: 10.1038/sj.emboj.7600942

PubMed ID: 16982605

Title: Phosphorylation of specific serine residues in the PKR activation domain of PACT is essential for its ability to mediate apoptosis.

PubMed ID: 16982605

DOI: 10.1074/jbc.m607714200

PubMed ID: 17452327

Title: Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA.

PubMed ID: 17452327

DOI: 10.1074/jbc.m611768200

PubMed ID: 18096616

Title: Interaction of human tRNA-dihydrouridine synthase-2 with interferon-induced protein kinase PKR.

PubMed ID: 18096616

DOI: 10.1093/nar/gkm1129

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18421256

Title: Interactions between the double-stranded RNA-binding proteins TRBP and PACT define the Medipal domain that mediates protein-protein interactions.

PubMed ID: 18421256

DOI: 10.4161/rna.5.2.6069

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21228243

Title: Ebolavirus proteins suppress the effects of small interfering RNA by direct interaction with the mammalian RNA interference pathway.

PubMed ID: 21228243

DOI: 10.1128/jvi.01160-10

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22214662

Title: The RAX/PACT-PKR stress response pathway promotes p53 sumoylation and activation, leading to G(1) arrest.

PubMed ID: 22214662

DOI: 10.4161/cc.11.2.18999

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23870315

Title: Mutual antagonism between the Ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome.

PubMed ID: 23870315

DOI: 10.1016/j.chom.2013.06.010

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 29084250

Title: KSHV inhibits stress granule formation by viral ORF57 blocking PKR activation.

PubMed ID: 29084250

DOI: 10.1371/journal.ppat.1006677

PubMed ID: 18243799

Title: DYT16, a novel young-onset dystonia-parkinsonism disorder: identification of a segregating mutation in the stress-response protein PRKRA.

PubMed ID: 18243799

DOI: 10.1016/s1474-4422(08)70022-x

PubMed ID: 18420150

Title: A heterozygous frameshift mutation in PRKRA (DYT16) associated with generalised dystonia in a German patient.

PubMed ID: 18420150

DOI: 10.1016/s1474-4422(08)70075-9

Sequence Information:

  • Length: 313
  • Mass: 34404
  • Checksum: 9B01637E6194827E
  • Sequence:
    • MSQSRHRAEA PPLEREDSGT FSLGKMITAK PGKTPIQVLH EYGMKTKNIP VYECERSDVQ 
IHVPTFTFRV TVGDITCTGE GTSKKLAKHR AAEAAINILK ANASICFAVP DPLMPDPSKQ 
PKNQLNPIGS LQELAIHHGW RLPEYTLSQE GGPAHKREYT TICRLESFME TGKGASKKQA 
KRNAAEKFLA KFSNISPENH ISLTNVVGHS LGCTWHSLRN SPGEKINLLK RSLLSIPNTD 
YIQLLSEIAK EQGFNITYLD IDELSANGQY QCLAELSTSP ITVCHGSGIS CGNAQSDAAH 
NALQYLKIIA ERK

Genular Protein ID: 3823374918

Symbol: A0A7I2V2I8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A7I2V2I8

Database IDs:

ARBA 2 AlphaFoldDB 1 Bgee 1 CDD 2 CTD 1 DisGeNET 1 EMBL 1 Ensembl 2 GO 2 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 NCBI Taxonomy 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 228
  • Mass: 25246
  • Checksum: EFD03495C562FF6B
  • Sequence:
    • MQVFGELNFF VFSSSKISWL SFAVPDPLMP DPSKQPKNQL NPIGSLQELA IHHGWRLPEY 
TLSQEGGPAH KREYTTICRL ESFMETGKGA SKKQAKRNAA EKFLAKFSNI SPENHISLTN 
VVGHSLGCTW HSLRNSPGEK INLLKRSLLS IPNTDYIQLL SEIAKEQGFN ITYLDIDELS 
ANGQYQCLAE LSTSPITVCH GSGISCGNAQ SDAAHNALQY LKIIAERK

Genular Protein ID: 2017973748

Symbol: B4DJC7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DJC7

Database IDs:

ARBA 2 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 3 GO 3 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 3 SMART 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 200
  • Mass: 22070
  • Checksum: 7A678F8031F6233F
  • Sequence:
    • MPDPSKQPKN QLNPIGSLQE LAIHHGWRLP EYTLSQEGGP AHKREYTTIC RLESFMETGK 
GASKKQAKRN AAEKFLAKFS NISPENHISL TNVVGHSLGC TWHSLRNSPG EKINLLKRSL 
LSIPNTDYIQ LLSEIAKEQG FNITYLDIDE LSANGQYQCL AELSTSPITV CHGSGISCGN 
AQSDAAHNAL QYLKIIAERK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.