Details for: VAMP8
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 207.9138
Cell Significance Index: -32.3400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 124.4532
Cell Significance Index: -50.5600 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 123.0375
Cell Significance Index: -50.6900 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 103.9243
Cell Significance Index: -49.0700 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 103.1328
Cell Significance Index: -53.0500 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 72.6578
Cell Significance Index: -48.7600 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 54.2240
Cell Significance Index: -51.7700 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 30.6053
Cell Significance Index: -37.7400 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 14.4296
Cell Significance Index: -44.3200 - Cell Name: precursor cell (CL0011115)
Fold Change: 11.4334
Cell Significance Index: 86.7000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 10.7475
Cell Significance Index: -42.4100 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 10.7008
Cell Significance Index: 286.2400 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 9.6284
Cell Significance Index: 59.2600 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 9.0420
Cell Significance Index: 83.2700 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 9.0279
Cell Significance Index: 95.9200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 7.8160
Cell Significance Index: 364.4200 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 7.2787
Cell Significance Index: -15.9300 - Cell Name: salivary gland glandular cell (CL1001596)
Fold Change: 7.0229
Cell Significance Index: 39.0900 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 6.0651
Cell Significance Index: 112.1000 - Cell Name: early promyelocyte (CL0002154)
Fold Change: 5.5752
Cell Significance Index: 35.5900 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 5.3993
Cell Significance Index: 35.8200 - Cell Name: peg cell (CL4033014)
Fold Change: 4.8354
Cell Significance Index: 111.7200 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 4.5667
Cell Significance Index: 134.1200 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 4.2518
Cell Significance Index: 199.8300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 4.2277
Cell Significance Index: 272.7500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 3.7809
Cell Significance Index: 281.7900 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 3.4384
Cell Significance Index: 93.5900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 3.2582
Cell Significance Index: 587.3600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 3.0553
Cell Significance Index: 158.7200 - Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: 3.0339
Cell Significance Index: 26.0700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 2.9335
Cell Significance Index: 360.7000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.2519
Cell Significance Index: 1229.8400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 2.1264
Cell Significance Index: 250.7700 - Cell Name: lactocyte (CL0002325)
Fold Change: 2.0670
Cell Significance Index: 267.0500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 1.9498
Cell Significance Index: 137.9000 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.8194
Cell Significance Index: 804.4100 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 1.7832
Cell Significance Index: 26.7200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.7398
Cell Significance Index: 172.1000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 1.5410
Cell Significance Index: 106.5700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.2449
Cell Significance Index: 33.2400 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.2278
Cell Significance Index: 5.1100 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 1.1169
Cell Significance Index: 6.9400 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: 0.9762
Cell Significance Index: 20.3600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.6174
Cell Significance Index: 105.4300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.5907
Cell Significance Index: 26.7800 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.5674
Cell Significance Index: 4.5300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.5299
Cell Significance Index: 105.1700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.4863
Cell Significance Index: 368.1100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3211
Cell Significance Index: 61.1100 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.2773
Cell Significance Index: 173.1500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.2507
Cell Significance Index: 72.1200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2497
Cell Significance Index: 7.1900 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.1950
Cell Significance Index: 5.4500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.1700
Cell Significance Index: 124.6400 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 0.0929
Cell Significance Index: 0.5800 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.0463
Cell Significance Index: 4.7300 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: 0.0336
Cell Significance Index: 3.8400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0031
Cell Significance Index: -2.3000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0105
Cell Significance Index: -19.7100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0186
Cell Significance Index: -34.2800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0250
Cell Significance Index: -38.4500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0291
Cell Significance Index: -39.6000 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0520
Cell Significance Index: -29.3400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0559
Cell Significance Index: -35.5200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0567
Cell Significance Index: -4.4900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0705
Cell Significance Index: -25.2800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0881
Cell Significance Index: -18.5500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0920
Cell Significance Index: -10.5400 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.0928
Cell Significance Index: -2.3700 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: -0.0947
Cell Significance Index: -0.9800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.1079
Cell Significance Index: -48.9700 - Cell Name: hepatic pit cell (CL2000054)
Fold Change: -0.1101
Cell Significance Index: -0.3000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1246
Cell Significance Index: -3.9900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.1301
Cell Significance Index: -21.1600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.1579
Cell Significance Index: -21.6900 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.1747
Cell Significance Index: -35.0500 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2053
Cell Significance Index: -10.3800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2061
Cell Significance Index: -24.0200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.2250
Cell Significance Index: -3.0700 - Cell Name: stem cell of epidermis (CL1000428)
Fold Change: -0.2387
Cell Significance Index: -0.7100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.3064
Cell Significance Index: -44.5400 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.3096
Cell Significance Index: -39.6900 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.3671
Cell Significance Index: -15.0400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3962
Cell Significance Index: -41.2500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.4170
Cell Significance Index: -32.0000 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -0.4571
Cell Significance Index: -7.8800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.5262
Cell Significance Index: -27.4100 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.5557
Cell Significance Index: -12.0400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.6782
Cell Significance Index: -45.6000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.6985
Cell Significance Index: -17.4600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.7285
Cell Significance Index: -15.5200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.7529
Cell Significance Index: -46.1600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.7530
Cell Significance Index: -46.2900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.7923
Cell Significance Index: -44.4600 - Cell Name: epidermal cell (CL0000362)
Fold Change: -0.7984
Cell Significance Index: -1.8000 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.8084
Cell Significance Index: -28.0900 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: -0.8370
Cell Significance Index: -7.9500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.8709
Cell Significance Index: -54.8900 - Cell Name: colonocyte (CL1000347)
Fold Change: -0.8722
Cell Significance Index: -5.3900 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.8742
Cell Significance Index: -25.7500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1863063411
Symbol: VAMP8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9614193
Title: Endobrevin, a novel synaptobrevin/VAMP-like protein preferentially associated with the early endosome.
PubMed ID: 9614193
DOI: 10.1091/mbc.9.6.1549
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12130530
Title: Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion.
PubMed ID: 12130530
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23217709
Title: The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes.
PubMed ID: 23217709
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25648148
Title: Starvation-induced MTMR13 and RAB21 activity regulates VAMP8 to promote autophagosome-lysosome fusion.
PubMed ID: 25648148
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 31806350
Title: The ER-Localized Transmembrane Protein TMEM39A/SUSR2 Regulates Autophagy by Controlling the Trafficking of the PtdIns(4)P Phosphatase SAC1.
PubMed ID: 31806350
PubMed ID: 33422265
Title: ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation.
PubMed ID: 33422265
PubMed ID: 31694946
Title: VAMP8 Contributes to the TRIM6-Mediated Type I Interferon Antiviral Response during West Nile Virus Infection.
PubMed ID: 31694946
DOI: 10.1128/jvi.01454-19
PubMed ID: 30061757
Title: Nepsilon-fatty acylation of multiple membrane-associated proteins by Shigella IcsB effector to modulate host function.
PubMed ID: 30061757
PubMed ID: 25686604
Title: ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes.
PubMed ID: 25686604
DOI: 10.1038/nature14147
Sequence Information:
- Length: 100
- Mass: 11438
- Checksum: 018B986442BBD9B6
- Sequence:
MEEASEGGGN DRVRNLQSEV EGVKNIMTQN VERILARGEN LEHLRNKTED LEATSEHFKT TSQKVARKFW WKNVKMIVLI CVIVFIIILF IVLFATGAFS
Genular Protein ID: 2800197288
Symbol: B8ZZT4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 99
- Mass: 11192
- Checksum: B10BC86EE764B9A8
- Sequence:
MEEASEGGGN DRVRNLQSEV EGVKNIMTQN VERILARGEN LEHLRNKTED LEATPGAEAS CFREEVTPKL SKVWSLKFCV QRGGWLWLSE SCVNSWLLV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.