Details for: AKAP9

Gene ID: 10142

Symbol: AKAP9

Ensembl ID: ENSG00000127914

Description: A-kinase anchoring protein 9

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 4.58
    Marker Score: 19,106
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 3.98
    Marker Score: 88,851
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 3.81
    Marker Score: 128,578
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 3.74
    Marker Score: 2,817
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 3.63
    Marker Score: 15,154
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 3.61
    Marker Score: 12,114
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 3.54
    Marker Score: 62,816
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 3.53
    Marker Score: 7,744
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 3.42
    Marker Score: 9,758
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 3.37
    Marker Score: 1,876
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 3.35
    Marker Score: 4,178
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 3.34
    Marker Score: 29,053
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 3.27
    Marker Score: 11,244
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 3.26
    Marker Score: 17,089
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 3.16
    Marker Score: 14,638
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 3.08
    Marker Score: 2,736
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 3
    Marker Score: 2,589
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 2.99
    Marker Score: 16,042
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 2.95
    Marker Score: 1,492
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 2.93
    Marker Score: 1,960
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 2.85
    Marker Score: 1,350
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 2.81
    Marker Score: 1,469
  • Cell Name: granule cell (CL0000120)
    Fold Change: 2.79
    Marker Score: 21,045
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 2.78
    Marker Score: 1,929
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 2.76
    Marker Score: 3,719
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 2.75
    Marker Score: 2,119
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 2.74
    Marker Score: 2,959
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.74
    Marker Score: 2,887
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 2.72
    Marker Score: 1,435
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 2.72
    Marker Score: 7,296
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.72
    Marker Score: 3,288
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.71
    Marker Score: 11,362
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 2.71
    Marker Score: 43,558
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.65
    Marker Score: 1,542
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 2.64
    Marker Score: 762
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 2.63
    Marker Score: 628
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 2.62
    Marker Score: 5,046
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.61
    Marker Score: 52,005
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.61
    Marker Score: 763
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 2.61
    Marker Score: 9,264
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.59
    Marker Score: 2,469
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: 2.59
    Marker Score: 4,918
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 2.57
    Marker Score: 1,233
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 2.54
    Marker Score: 1,475
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 2.54
    Marker Score: 1,930
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 2.53
    Marker Score: 1,158
  • Cell Name: basal cell (CL0000646)
    Fold Change: 2.53
    Marker Score: 3,267
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 2.52
    Marker Score: 750
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.52
    Marker Score: 37,605
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 2.51
    Marker Score: 1,299
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 2.51
    Marker Score: 937
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 2.5
    Marker Score: 2,828
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 2.5
    Marker Score: 1,011
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 2.49
    Marker Score: 2,662
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 2.48
    Marker Score: 3,489
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.47
    Marker Score: 93,802
  • Cell Name: podocyte (CL0000653)
    Fold Change: 2.47
    Marker Score: 913
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.47
    Marker Score: 52,631
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 2.46
    Marker Score: 2,136
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 2.45
    Marker Score: 1,189
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.44
    Marker Score: 18,735
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.42
    Marker Score: 2,787
  • Cell Name: fat cell (CL0000136)
    Fold Change: 2.42
    Marker Score: 1,351
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 2.4
    Marker Score: 1,696
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 2.4
    Marker Score: 1,183
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 2.38
    Marker Score: 971
  • Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
    Fold Change: 2.36
    Marker Score: 709
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 2.35
    Marker Score: 17,528
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 2.35
    Marker Score: 741
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 2.35
    Marker Score: 5,392
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 2.33
    Marker Score: 5,318
  • Cell Name: intestine goblet cell (CL0019031)
    Fold Change: 2.32
    Marker Score: 2,220
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.3
    Marker Score: 79,626
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2.3
    Marker Score: 2,539
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 2.29
    Marker Score: 797
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.26
    Marker Score: 83,421
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 2.25
    Marker Score: 1,539
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: 2.25
    Marker Score: 663
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 2.25
    Marker Score: 782
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 2.24
    Marker Score: 2,058
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 2.24
    Marker Score: 1,471
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 2.24
    Marker Score: 2,371
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 2.23
    Marker Score: 3,156
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.23
    Marker Score: 9,239
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 2.23
    Marker Score: 510
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 2.22
    Marker Score: 487
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 2.22
    Marker Score: 2,253
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 2.22
    Marker Score: 801
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 2.22
    Marker Score: 637
  • Cell Name: mesenchymal lymphangioblast (CL0005021)
    Fold Change: 2.21
    Marker Score: 493
  • Cell Name: type I pneumocyte (CL0002062)
    Fold Change: 2.2
    Marker Score: 2,650
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.2
    Marker Score: 3,238
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 2.2
    Marker Score: 1,663
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 2.19
    Marker Score: 3,885
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 2.19
    Marker Score: 918
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 2.18
    Marker Score: 542
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 2.18
    Marker Score: 1,487
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 2.18
    Marker Score: 555
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 2.18
    Marker Score: 791
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 2.17
    Marker Score: 2,097

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** AKAP9 is a member of the A-Kinase Anchoring Protein (AKAP) family, which is characterized by its ability to bind and regulate protein kinase A (PKA) activity. AKAP9 is a large protein (approximately 100 kDa) with multiple domains, including a PKA binding domain, a proline-rich domain, and a C-terminal domain. Its unique structure allows it to interact with various cellular components, including PKA, microtubules, and the plasma membrane. **Pathways and Functions:** AKAP9 is involved in numerous cellular processes, including: 1. **Cardiac Conduction:** AKAP9 regulates the action potential in cardiac muscle cells by modulating PKA activity and influencing the expression of ion channels. 2. **Cell Cycle Regulation:** AKAP9 interacts with PKA and cyclin-dependent kinases (CDKs) to regulate the cell cycle, particularly during the G2/M phase. 3. **Cytoskeleton Organization:** AKAP9 is involved in maintaining the organization and dynamics of microtubules, which is crucial for cell shape, movement, and division. 4. **Neurotransmission:** AKAP9 regulates synaptic transmission by modulating PKA activity and influencing the expression of ion channels and receptors. 5. **Cell Signaling:** AKAP9 interacts with various signaling molecules, including Braf and Raf1, to regulate cell growth, differentiation, and survival. **Clinical Significance:** Dysregulation of AKAP9 has been implicated in various diseases, including: 1. **Cardiac Arrhythmias:** Mutations in AKAP9 have been associated with arrhythmogenic right ventricular cardiomyopathy (ARVC). 2. **Neurodegenerative Disorders:** AKAP9 has been implicated in Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders, where it may play a role in regulating synaptic transmission and plasticity. 3. **Cancer:** AKAP9 has been shown to regulate cell growth and survival in various cancer types, including breast, lung, and colon cancer. In conclusion, AKAP9 is a multifunctional protein that plays a critical role in maintaining cellular homeostasis. Its dysregulation has been implicated in various diseases, highlighting the need for further research into its mechanisms of action and potential therapeutic applications. As an expert immunologist, I emphasize the importance of understanding the complex interactions between AKAP9 and other cellular components to develop effective treatments for these diseases.

Genular Protein ID: 3941629561

Symbol: AKAP9_HUMAN

Name: A-kinase anchor protein 9

UniProtKB Accession Codes:

Q99996 A4D1F0 A4D1F2 A4D1F4 O14869 O43355 O94895 Q75N20 Q9UQH3 Q9UQQ4 Q9Y6B8 Q9Y6Y2

Database IDs:

AGR 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CTD 1 CarbonylDB 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 13 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 35 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 Reactome 10 RefSeq 2 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9482789

Title: Yotiao, a novel protein of neuromuscular junction and brain that interacts with specific splice variants of NMDA receptor subunit NR1.

PubMed ID: 9482789

DOI: 10.1523/jneurosci.18-06-02017.1998

PubMed ID: 10202149

Title: Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450.

PubMed ID: 10202149

DOI: 10.1093/emboj/18.7.1858

PubMed ID: 10358086

Title: Characterization of a novel giant scaffolding protein, CG-NAP, that anchors multiple signaling enzymes to centrosome and the Golgi apparatus.

PubMed ID: 10358086

DOI: 10.1074/jbc.274.24.17267

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 9915845

Title: AKAP350, a multiply spliced protein kinase A-anchoring protein associated with centrosomes.

PubMed ID: 9915845

DOI: 10.1074/jbc.274.5.3055

PubMed ID: 9872452

Title: Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 9872452

DOI: 10.1093/dnares/5.5.277

PubMed ID: 12163479

Title: AKAP350 at the Golgi apparatus. II. Association of AKAP350 with a novel chloride intracellular channel (CLIC) family member.

PubMed ID: 12163479

DOI: 10.1074/jbc.m112277200

PubMed ID: 12270714

Title: Centrosomal anchoring of the protein kinase CK1delta mediated by attachment to the large, coiled-coil scaffolding protein CG-NAP/AKAP450.

PubMed ID: 12270714

DOI: 10.1016/s0022-2836(02)00857-4

PubMed ID: 11799244

Title: Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel.

PubMed ID: 11799244

DOI: 10.1126/science.1066843

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 15047863

Title: AKAP350 interaction with cdc42 interacting protein 4 at the Golgi apparatus.

PubMed ID: 15047863

DOI: 10.1091/mbc.e03-10-0757

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 19242490

Title: Microtubule nucleation at the cis-side of the Golgi apparatus requires AKAP450 and GM130.

PubMed ID: 19242490

DOI: 10.1038/emboj.2009.47

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25217626

Title: A newly identified myomegalin isoform functions in Golgi microtubule organization and ER-Golgi transport.

PubMed ID: 25217626

DOI: 10.1242/jcs.155408

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25657325

Title: CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly.

PubMed ID: 25657325

DOI: 10.1091/mbc.e14-09-1366

PubMed ID: 27666745

Title: Molecular pathway of microtubule organization at the Golgi apparatus.

PubMed ID: 27666745

DOI: 10.1016/j.devcel.2016.08.009

PubMed ID: 28814570

Title: EB1 and EB3 regulate microtubule minus end organization and Golgi morphology.

PubMed ID: 28814570

DOI: 10.1083/jcb.201701024

PubMed ID: 28089391

Title: CAMSAP3-dependent microtubule dynamics regulates Golgi assembly in epithelial cells.

PubMed ID: 28089391

DOI: 10.1016/j.jgg.2016.11.005

PubMed ID: 29162697

Title: EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.

PubMed ID: 29162697

DOI: 10.1073/pnas.1705682114

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 18093912

Title: Mutation of an A-kinase-anchoring protein causes long-QT syndrome.

PubMed ID: 18093912

DOI: 10.1073/pnas.0710527105

Sequence Information:

  • Length: 3907
  • Mass: 452987
  • Checksum: 81761B4341430CDF
  • Sequence:
    • MEDEERQKKL EAGKAKLAQF RQRKAQSDGQ SPSKKQKKKR KTSSSKHDVS AHHDLNIDQS 
QCNEMYINSS QRVESTVIPE STIMRTLHSG EITSHEQGFS VELESEISTT ADDCSSEVNG 
CSFVMRTGKP TNLLREEEFG VDDSYSEQGA QDSPTHLEMM ESELAGKQHE IEELNRELEE 
MRVTYGTEGL QQLQEFEAAI KQRDGIITQL TANLQQARRE KDETMREFLE LTEQSQKLQI 
QFQQLQASET LRNSTHSSTA ADLLQAKQQI LTHQQQLEEQ DHLLEDYQKK KEDFTMQISF 
LQEKIKVYEM EQDKKVENSN KEEIQEKETI IEELNTKIIE EEKKTLELKD KLTTADKLLG 
ELQEQIVQKN QEIKNMKLEL TNSKQKERQS SEEIKQLMGT VEELQKRNHK DSQFETDIVQ 
RMEQETQRKL EQLRAELDEM YGQQIVQMKQ ELIRQHMAQM EEMKTRHKGE MENALRSYSN 
ITVNEDQIKL MNVAINELNI KLQDTNSQKE KLKEELGLIL EEKCALQRQL EDLVEELSFS 
REQIQRARQT IAEQESKLNE AHKSLSTVED LKAEIVSASE SRKELELKHE AEVTNYKIKL 
EMLEKEKNAV LDRMAESQEA ELERLRTQLL FSHEEELSKL KEDLEIEHRI NIEKLKDNLG 
IHYKQQIDGL QNEMSQKIET MQFEKDNLIT KQNQLILEIS KLKDLQQSLV NSKSEEMTLQ 
INELQKEIEI LRQEEKEKGT LEQEVQELQL KTELLEKQMK EKENDLQEKF AQLEAENSIL 
KDEKKTLEDM LKIHTPVSQE ERLIFLDSIK SKSKDSVWEK EIEILIEENE DLKQQCIQLN 
EEIEKQRNTF SFAEKNFEVN YQELQEEYAC LLKVKDDLED SKNKQELEYK SKLKALNEEL 
HLQRINPTTV KMKSSVFDED KTFVAETLEM GEVVEKDTTE LMEKLEVTKR EKLELSQRLS 
DLSEQLKQKH GEISFLNEEV KSLKQEKEQV SLRCRELEII INHNRAENVQ SCDTQVSSLL 
DGVVTMTSRG AEGSVSKVNK SFGEESKIMV EDKVSFENMT VGEESKQEQL ILDHLPSVTK 
ESSLRATQPS ENDKLQKELN VLKSEQNDLR LQMEAQRICL SLVYSTHVDQ VREYMENEKD 
KALCSLKEEL IFAQEEKIKE LQKIHQLELQ TMKTQETGDE GKPLHLLIGK LQKAVSEECS 
YFLQTLCSVL GEYYTPALKC EVNAEDKENS GDYISENEDP ELQDYRYEVQ DFQENMHTLL 
NKVTEEYNKL LVLQTRLSKI WGQQTDGMKL EFGEENLPKE ETEFLSIHSQ MTNLEDIDVN 
HKSKLSSLQD LEKTKLEEQV QELESLISSL QQQLKETEQN YEAEIHCLQK RLQAVSESTV 
PPSLPVDSVV ITESDAQRTM YPGSCVKKNI DGTIEFSGEF GVKEETNIVK LLEKQYQEQL 
EEEVAKVIVS MSIAFAQQTE LSRISGGKEN TASSKQAHAV CQQEQHYFNE MKLSQDQIGF 
QTFETVDVKF KEEFKPLSKE LGEHGKEILL SNSDPHDIPE SKDCVLTISE EMFSKDKTFI 
VRQSIHDEIS VSSMDASRQL MLNEEQLEDM RQELVRQYQE HQQATELLRQ AHMRQMERQR 
EDQEQLQEEI KRLNRQLAQR SSIDNENLVS ERERVLLEEL EALKQLSLAG REKLCCELRN 
SSTQTQNGNE NQGEVEEQTF KEKELDRKPE DVPPEILSNE RYALQKANNR LLKILLEVVK 
TTAAVEETIG RHVLGILDRS SKSQSSASLI WRSEAEASVK SCVHEEHTRV TDESIPSYSG 
SDMPRNDINM WSKVTEEGTE LSQRLVRSGF AGTEIDPENE ELMLNISSRL QAAVEKLLEA 
ISETSSQLEH AKVTQTELMR ESFRQKQEAT ESLKCQEELR ERLHEESRAR EQLAVELSKA 
EGVIDGYADE KTLFERQIQE KTDIIDRLEQ ELLCASNRLQ ELEAEQQQIQ EERELLSRQK 
EAMKAEAGPV EQQLLQETEK LMKEKLEVQC QAEKVRDDLQ KQVKALEIDV EEQVSRFIEL 
EQEKNTELMD LRQQNQALEK QLEKMRKFLD EQAIDREHER DVFQQEIQKL EQQLKVVPRF 
QPISEHQTRE VEQLANHLKE KTDKCSELLL SKEQLQRDIQ ERNEEIEKLE FRVRELEQAL 
LVSADTFQKV EDRKHFGAVE AKPELSLEVQ LQAERDAIDR KEKEITNLEE QLEQFREELE 
NKNEEVQQLH MQLEIQKKES TTRLQELEQE NKLFKDDMEK LGLAIKESDA MSTQDQHVLF 
GKFAQIIQEK EVEIDQLNEQ VTKLQQQLKI TTDNKVIEEK NELIRDLETQ IECLMSDQEC 
VKRNREEEIE QLNEVIEKLQ QELANIGQKT SMNAHSLSEE ADSLKHQLDV VIAEKLALEQ 
QVETANEEMT FMKNVLKETN FKMNQLTQEL FSLKRERESV EKIQSIPENS VNVAIDHLSK 
DKPELEVVLT EDALKSLENQ TYFKSFEENG KGSIINLETR LLQLESTVSA KDLELTQCYK 
QIKDMQEQGQ FETEMLQKKI VNLQKIVEEK VAAALVSQIQ LEAVQEYAKF CQDNQTISSE 
PERTNIQNLN QLREDELGSD ISALTLRISE LESQVVEMHT SLILEKEQVE IAEKNVLEKE 
KKLLELQKLL EGNEKKQREK EKKRSPQDVE VLKTTTELFH SNEESGFFNE LEALRAESVA 
TKAELASYKE KAEKLQEELL VKETNMTSLQ KDLSQVRDHL AEAKEKLSIL EKEDETEVQE 
SKKACMFEPL PIKLSKSIAS QTDGTLKISS SNQTPQILVK NAGIQINLQS ECSSEEVTEI 
ISQFTEKIEK MQELHAAEIL DMESRHISET ETLKREHYVA VQLLKEECGT LKAVIQCLRS 
KEGSSIPELA HSDAYQTREI CSSDSGSDWG QGIYLTHSQG FDIASEGRGE ESESATDSFP 
KKIKGLLRAV HNEGMQVLSL TESPYSDGED HSIQQVSEPW LEERKAYINT ISSLKDLITK 
MQLQREAEVY DSSQSHESFS DWRGELLLAL QQVFLEERSV LLAAFRTELT ALGTTDAVGL 
LNCLEQRIQE QGVEYQAAME CLQKADRRSL LSEIQALHAQ MNGRKITLKR EQESEKPSQE 
LLEYNIQQKQ SQMLEMQVEL SSMKDRATEL QEQLSSEKMV VAELKSELAQ TKLELETTLK 
AQHKHLKELE AFRLEVKDKT DEVHLLNDTL ASEQKKSREL QWALEKEKAK LGRSEERDKE 
ELEDLKFSLE SQKQRNLQLN LLLEQQKQLL NESQQKIESQ RMLYDAQLSE EQGRNLELQV 
LLESEKVRIR EMSSTLDRER ELHAQLQSSD GTGQSRPPLP SEDLLKELQK QLEEKHSRIV 
ELLNETEKYK LDSLQTRQQM EKDRQVHRKT LQTEQEANTE GQKKMHELQS KVEDLQRQLE 
EKRQQVYKLD LEGQRLQGIM QEFQKQELER EEKRESRRIL YQNLNEPTTW SLTSDRTRNW 
VLQQKIEGET KESNYAKLIE MNGGGTGCNH ELEMIRQKLQ CVASKLQVLP QKASERLQFE 
TADDEDFIWV QENIDEIILQ LQKLTGQQGE EPSLVSPSTS CGSLTERLLR QNAELTGHIS 
QLTEEKNDLR NMVMKLEEQI RWYRQTGAGR DNSSRFSLNG GANIEAIIAS EKEVWNREKL 
TLQKSLKRAE AEVYKLKAEL RNDSLLQTLS PDSEHVTLKR IYGKYLRAES FRKALIYQKK 
YLLLLLGGFQ ECEDATLALL ARMGGQPAFT DLEVITNRPK GFTRFRSAVR VSIAISRMKF 
LVRRWHRVTG SVSININRDG FGLNQGAEKT DSFYHSSGGL ELYGEPRHTT YRSRSDLDYI 
RSPLPFQNRY PGTPADFNPG SLACSQLQNY DPDRALTDYI TRLEALQRRL GTIQSGSTTQ 
FHAGMRR

Genular Protein ID: 3144095179

Symbol: Q6PJH3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6PJH3

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 GO 6 GenomeRNAi 1 IntAct 1 InterPro 1 KEGG 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 PharmGKB 1 ProteomicsDB 1 RefSeq 2 SAM 2 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 314
  • Mass: 36171
  • Checksum: 70D4D3357B87EAEF
  • Sequence:
    • MEDEERQKKL EAGKAKLAQF RQRKAQSDGQ SPSKKQKKKR KTSSSKHDVS AHHDLNIDQS 
QCNEMYINSS QRVESTVIPE STIMRTLHSG EITSHEQGFS VELESEISTT ADDCSSEVNG 
CSFVMRTGKP TNLLREEEFG VDDSYSEQGA QDSPTHLEMM ESELAGKQHE IEELNRELEE 
MRVTYGTEGL QQLQEFEAAI KQRDGIITQL TANLQQARRE KDETMREFLE LTEQSQKLQI 
QFQQLQASET LRNSTHSSTA ADLLQAKQQI LTHQQQLEEQ DHLLEDYQKK KEDFTMQISF 
LQEKIKVYEM VCLF

Genular Protein ID: 859980428

Symbol: Q5GIA7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5GIA7

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 4 Genevisible 1 GenomeRNAi 1 InterPro 1 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 PharmGKB 1 RefSeq 2 SAM 2

Sequence Information:

  • Length: 1016
  • Mass: 118199
  • Checksum: 58C4F432AF444604
  • Sequence:
    • DNENLVSERE RVLLEELEAL KQLSLAGREK LCCELRNSST QTQNGNENQG EVEEQTFKEK 
ELDRKPEDVP PEILSNERYA LQKANNRLLK ILLEVVKTTA AVEETIGRHV LGILDRSSKS 
QSSASLIWRS EAEASVKSCV HEEHTRVTDE SIPSYSGSDM PRNDINMWSK VTEEGTELSQ 
RLVRSGFAGT EIDPENEELM LNISSRLQAA VEKLLEAISE TSSQLEHAKV TQTELMRESF 
RQKQEATESL KCQEELRERL HEESRAREQL AVELSKAEGV IDGYADEKTL FERQIQEKTD 
IIDRLEQELL CASNRLQELE AEQQQIQEER ELLSRQKEAM KAEAGPVEQQ LLQETEKLMK 
EKLEVQCQAE KVRDDLQKQV KALEIDVEEQ VSRFIELEQE KNTELMDLRQ QNQALEKQLE 
KMRKFLDEQA IDREHERDVF QQEIQKLEQQ LKVVPRFQPI SEHQTREVEQ LANHLKEKTD 
KCSELLLSKE QLQRDIQERN EEIEKLEFRV RELEQALLVS ADTFQKVEDR KHFGAVEAKP 
ELSLEVQLQA ERDAIDRKEK EITNLEEQLE QFREELENKN EEVQQLHMQL EIQKKESTTR 
LQELEQENKL FKDDMEKLGL AIKESDAMST QDQHVLFGKF AQIIQEKEVE IDQLNEQVTK 
LQQQLKITTD NKVIEEKNEL IRDLETQIEC LMSDQECVKR NREEEIEQLN EVIEKLQQEL 
ANIGQKTSMN AHSLSEEADS LKHQLDVVIA EKLALEQQVE TANEEMTFMK NVLKETNFKM 
NQLTQELFSL KRERESVEKI QSIPENSVNV AIDHLSKDKP ELEVVLTEDA LKSLENQTYF 
RSFEENGKGS IINLETRLLQ LESTVSAKDL ELTQCYKQIK DMQEQGQFET EMLQKKIVNL 
QKIVEEKVAA ALVSQIQLEA VQEYAKFCQD NQTISSEPER TNIQNLNQLR EDELGSDISA 
LTLRISELES QVVEMHTSLI LEKEQVEIAE KNVLEKEKKL LELQKLLEGN EKKQRE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.