Details for: AKAP9

Gene ID: 10142

Symbol: AKAP9

Ensembl ID: ENSG00000127914

Description: A-kinase anchoring protein 9

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 850.1064
    Cell Significance Index: -132.2300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 508.3909
    Cell Significance Index: -128.9500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 306.3611
    Cell Significance Index: -144.6400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 282.8504
    Cell Significance Index: -114.9100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 259.9219
    Cell Significance Index: -133.7000
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 215.9243
    Cell Significance Index: -144.8900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 120.3937
    Cell Significance Index: -114.9500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 111.6098
    Cell Significance Index: -137.6100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 48.0540
    Cell Significance Index: -128.7300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 36.2198
    Cell Significance Index: -142.9300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 34.0751
    Cell Significance Index: -104.6600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 27.1408
    Cell Significance Index: -59.4000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 4.5017
    Cell Significance Index: 61.4200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 3.8193
    Cell Significance Index: 234.7500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 3.2923
    Cell Significance Index: 252.6500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 3.2230
    Cell Significance Index: 350.5600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 2.9487
    Cell Significance Index: 57.5500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 2.8905
    Cell Significance Index: 521.0700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.7666
    Cell Significance Index: 992.3200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 2.6497
    Cell Significance Index: 68.1100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.5312
    Cell Significance Index: 502.3200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.4688
    Cell Significance Index: 495.2400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 2.4318
    Cell Significance Index: 67.9600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 2.4138
    Cell Significance Index: 296.8000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.3281
    Cell Significance Index: 105.5300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 2.2170
    Cell Significance Index: 284.2100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.2157
    Cell Significance Index: 63.8400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.1449
    Cell Significance Index: 120.3600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.0930
    Cell Significance Index: 1447.6200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 2.0901
    Cell Significance Index: 97.4500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 2.0523
    Cell Significance Index: 49.2200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.0266
    Cell Significance Index: 278.3100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.6877
    Cell Significance Index: 921.6900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.4821
    Cell Significance Index: 77.2000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.3898
    Cell Significance Index: 89.6600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.3714
    Cell Significance Index: 86.4400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.3388
    Cell Significance Index: 591.9100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.9265
    Cell Significance Index: 420.4900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.8674
    Cell Significance Index: 40.7700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.7515
    Cell Significance Index: 6.9200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.6967
    Cell Significance Index: 30.8200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.5756
    Cell Significance Index: 30.2200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.5716
    Cell Significance Index: 15.0300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.5538
    Cell Significance Index: 9.4900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.4725
    Cell Significance Index: 80.6900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.4544
    Cell Significance Index: 30.5600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.4224
    Cell Significance Index: 795.2500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.3828
    Cell Significance Index: 10.4200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3787
    Cell Significance Index: 341.9700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.3644
    Cell Significance Index: 231.4200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.3326
    Cell Significance Index: 243.8300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.3137
    Cell Significance Index: 11.8800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.2955
    Cell Significance Index: 38.1800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.2761
    Cell Significance Index: 425.0000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.2543
    Cell Significance Index: 469.0600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2325
    Cell Significance Index: 12.0800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.2174
    Cell Significance Index: 16.2000
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.2060
    Cell Significance Index: 4.7600
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 0.1466
    Cell Significance Index: 1.1300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1388
    Cell Significance Index: 9.8200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1198
    Cell Significance Index: 19.4900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1022
    Cell Significance Index: 10.1100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0453
    Cell Significance Index: 61.5700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0166
    Cell Significance Index: 3.1500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0154
    Cell Significance Index: 0.4100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0691
    Cell Significance Index: -51.2100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0707
    Cell Significance Index: -8.3400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0801
    Cell Significance Index: -60.6100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1099
    Cell Significance Index: -68.6400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1847
    Cell Significance Index: -104.1400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2199
    Cell Significance Index: -22.4700
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.2953
    Cell Significance Index: -3.5200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2971
    Cell Significance Index: -62.5700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.3992
    Cell Significance Index: -58.0300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.4247
    Cell Significance Index: -122.2000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.4405
    Cell Significance Index: -30.4600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.4851
    Cell Significance Index: -17.0500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.7098
    Cell Significance Index: -81.3200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.7109
    Cell Significance Index: -17.7700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.7607
    Cell Significance Index: -86.8300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.8508
    Cell Significance Index: -99.1500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.9153
    Cell Significance Index: -95.3100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.9563
    Cell Significance Index: -16.0100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -1.0404
    Cell Significance Index: -15.3600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.0596
    Cell Significance Index: -36.8200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -1.2058
    Cell Significance Index: -25.2400
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -1.2531
    Cell Significance Index: -26.0000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.2539
    Cell Significance Index: -99.3100
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -1.4256
    Cell Significance Index: -24.0200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -1.4976
    Cell Significance Index: -36.5400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.6938
    Cell Significance Index: -54.2500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -1.9284
    Cell Significance Index: -42.2300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -1.9955
    Cell Significance Index: -42.6600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -2.0890
    Cell Significance Index: -59.8800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -2.1593
    Cell Significance Index: -61.6200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -2.2608
    Cell Significance Index: -60.5800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -2.2813
    Cell Significance Index: -139.8700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -2.3748
    Cell Significance Index: -51.4500
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -2.4621
    Cell Significance Index: -36.3400
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -2.5367
    Cell Significance Index: -38.0100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** AKAP9 is a member of the A-Kinase Anchoring Protein (AKAP) family, which is characterized by its ability to bind and regulate protein kinase A (PKA) activity. AKAP9 is a large protein (approximately 100 kDa) with multiple domains, including a PKA binding domain, a proline-rich domain, and a C-terminal domain. Its unique structure allows it to interact with various cellular components, including PKA, microtubules, and the plasma membrane. **Pathways and Functions:** AKAP9 is involved in numerous cellular processes, including: 1. **Cardiac Conduction:** AKAP9 regulates the action potential in cardiac muscle cells by modulating PKA activity and influencing the expression of ion channels. 2. **Cell Cycle Regulation:** AKAP9 interacts with PKA and cyclin-dependent kinases (CDKs) to regulate the cell cycle, particularly during the G2/M phase. 3. **Cytoskeleton Organization:** AKAP9 is involved in maintaining the organization and dynamics of microtubules, which is crucial for cell shape, movement, and division. 4. **Neurotransmission:** AKAP9 regulates synaptic transmission by modulating PKA activity and influencing the expression of ion channels and receptors. 5. **Cell Signaling:** AKAP9 interacts with various signaling molecules, including Braf and Raf1, to regulate cell growth, differentiation, and survival. **Clinical Significance:** Dysregulation of AKAP9 has been implicated in various diseases, including: 1. **Cardiac Arrhythmias:** Mutations in AKAP9 have been associated with arrhythmogenic right ventricular cardiomyopathy (ARVC). 2. **Neurodegenerative Disorders:** AKAP9 has been implicated in Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders, where it may play a role in regulating synaptic transmission and plasticity. 3. **Cancer:** AKAP9 has been shown to regulate cell growth and survival in various cancer types, including breast, lung, and colon cancer. In conclusion, AKAP9 is a multifunctional protein that plays a critical role in maintaining cellular homeostasis. Its dysregulation has been implicated in various diseases, highlighting the need for further research into its mechanisms of action and potential therapeutic applications. As an expert immunologist, I emphasize the importance of understanding the complex interactions between AKAP9 and other cellular components to develop effective treatments for these diseases.

Genular Protein ID: 3941629561

Symbol: AKAP9_HUMAN

Name: A-kinase anchor protein 9

UniProtKB Accession Codes:

Q99996 A4D1F0 A4D1F2 A4D1F4 O14869 O43355 O94895 Q75N20 Q9UQH3 Q9UQQ4 Q9Y6B8 Q9Y6Y2

Database IDs:

AGR 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CTD 1 CarbonylDB 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 13 Ensembl 2 ExpressionAtlas 1 GO 35 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 Reactome 10 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9482789

Title: Yotiao, a novel protein of neuromuscular junction and brain that interacts with specific splice variants of NMDA receptor subunit NR1.

PubMed ID: 9482789

DOI: 10.1523/jneurosci.18-06-02017.1998

PubMed ID: 10202149

Title: Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450.

PubMed ID: 10202149

DOI: 10.1093/emboj/18.7.1858

PubMed ID: 10358086

Title: Characterization of a novel giant scaffolding protein, CG-NAP, that anchors multiple signaling enzymes to centrosome and the Golgi apparatus.

PubMed ID: 10358086

DOI: 10.1074/jbc.274.24.17267

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 9915845

Title: AKAP350, a multiply spliced protein kinase A-anchoring protein associated with centrosomes.

PubMed ID: 9915845

DOI: 10.1074/jbc.274.5.3055

PubMed ID: 9872452

Title: Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 9872452

DOI: 10.1093/dnares/5.5.277

PubMed ID: 12163479

Title: AKAP350 at the Golgi apparatus. II. Association of AKAP350 with a novel chloride intracellular channel (CLIC) family member.

PubMed ID: 12163479

DOI: 10.1074/jbc.m112277200

PubMed ID: 12270714

Title: Centrosomal anchoring of the protein kinase CK1delta mediated by attachment to the large, coiled-coil scaffolding protein CG-NAP/AKAP450.

PubMed ID: 12270714

DOI: 10.1016/s0022-2836(02)00857-4

PubMed ID: 11799244

Title: Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel.

PubMed ID: 11799244

DOI: 10.1126/science.1066843

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 15047863

Title: AKAP350 interaction with cdc42 interacting protein 4 at the Golgi apparatus.

PubMed ID: 15047863

DOI: 10.1091/mbc.e03-10-0757

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 19242490

Title: Microtubule nucleation at the cis-side of the Golgi apparatus requires AKAP450 and GM130.

PubMed ID: 19242490

DOI: 10.1038/emboj.2009.47

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25217626

Title: A newly identified myomegalin isoform functions in Golgi microtubule organization and ER-Golgi transport.

PubMed ID: 25217626

DOI: 10.1242/jcs.155408

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25657325

Title: CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly.

PubMed ID: 25657325

DOI: 10.1091/mbc.e14-09-1366

PubMed ID: 27666745

Title: Molecular pathway of microtubule organization at the Golgi apparatus.

PubMed ID: 27666745

DOI: 10.1016/j.devcel.2016.08.009

PubMed ID: 28814570

Title: EB1 and EB3 regulate microtubule minus end organization and Golgi morphology.

PubMed ID: 28814570

DOI: 10.1083/jcb.201701024

PubMed ID: 28089391

Title: CAMSAP3-dependent microtubule dynamics regulates Golgi assembly in epithelial cells.

PubMed ID: 28089391

DOI: 10.1016/j.jgg.2016.11.005

PubMed ID: 29162697

Title: EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.

PubMed ID: 29162697

DOI: 10.1073/pnas.1705682114

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 18093912

Title: Mutation of an A-kinase-anchoring protein causes long-QT syndrome.

PubMed ID: 18093912

DOI: 10.1073/pnas.0710527105

Sequence Information:

  • Length: 3907
  • Mass: 452987
  • Checksum: 81761B4341430CDF
  • Sequence:
    • MEDEERQKKL EAGKAKLAQF RQRKAQSDGQ SPSKKQKKKR KTSSSKHDVS AHHDLNIDQS 
QCNEMYINSS QRVESTVIPE STIMRTLHSG EITSHEQGFS VELESEISTT ADDCSSEVNG 
CSFVMRTGKP TNLLREEEFG VDDSYSEQGA QDSPTHLEMM ESELAGKQHE IEELNRELEE 
MRVTYGTEGL QQLQEFEAAI KQRDGIITQL TANLQQARRE KDETMREFLE LTEQSQKLQI 
QFQQLQASET LRNSTHSSTA ADLLQAKQQI LTHQQQLEEQ DHLLEDYQKK KEDFTMQISF 
LQEKIKVYEM EQDKKVENSN KEEIQEKETI IEELNTKIIE EEKKTLELKD KLTTADKLLG 
ELQEQIVQKN QEIKNMKLEL TNSKQKERQS SEEIKQLMGT VEELQKRNHK DSQFETDIVQ 
RMEQETQRKL EQLRAELDEM YGQQIVQMKQ ELIRQHMAQM EEMKTRHKGE MENALRSYSN 
ITVNEDQIKL MNVAINELNI KLQDTNSQKE KLKEELGLIL EEKCALQRQL EDLVEELSFS 
REQIQRARQT IAEQESKLNE AHKSLSTVED LKAEIVSASE SRKELELKHE AEVTNYKIKL 
EMLEKEKNAV LDRMAESQEA ELERLRTQLL FSHEEELSKL KEDLEIEHRI NIEKLKDNLG 
IHYKQQIDGL QNEMSQKIET MQFEKDNLIT KQNQLILEIS KLKDLQQSLV NSKSEEMTLQ 
INELQKEIEI LRQEEKEKGT LEQEVQELQL KTELLEKQMK EKENDLQEKF AQLEAENSIL 
KDEKKTLEDM LKIHTPVSQE ERLIFLDSIK SKSKDSVWEK EIEILIEENE DLKQQCIQLN 
EEIEKQRNTF SFAEKNFEVN YQELQEEYAC LLKVKDDLED SKNKQELEYK SKLKALNEEL 
HLQRINPTTV KMKSSVFDED KTFVAETLEM GEVVEKDTTE LMEKLEVTKR EKLELSQRLS 
DLSEQLKQKH GEISFLNEEV KSLKQEKEQV SLRCRELEII INHNRAENVQ SCDTQVSSLL 
DGVVTMTSRG AEGSVSKVNK SFGEESKIMV EDKVSFENMT VGEESKQEQL ILDHLPSVTK 
ESSLRATQPS ENDKLQKELN VLKSEQNDLR LQMEAQRICL SLVYSTHVDQ VREYMENEKD 
KALCSLKEEL IFAQEEKIKE LQKIHQLELQ TMKTQETGDE GKPLHLLIGK LQKAVSEECS 
YFLQTLCSVL GEYYTPALKC EVNAEDKENS GDYISENEDP ELQDYRYEVQ DFQENMHTLL 
NKVTEEYNKL LVLQTRLSKI WGQQTDGMKL EFGEENLPKE ETEFLSIHSQ MTNLEDIDVN 
HKSKLSSLQD LEKTKLEEQV QELESLISSL QQQLKETEQN YEAEIHCLQK RLQAVSESTV 
PPSLPVDSVV ITESDAQRTM YPGSCVKKNI DGTIEFSGEF GVKEETNIVK LLEKQYQEQL 
EEEVAKVIVS MSIAFAQQTE LSRISGGKEN TASSKQAHAV CQQEQHYFNE MKLSQDQIGF 
QTFETVDVKF KEEFKPLSKE LGEHGKEILL SNSDPHDIPE SKDCVLTISE EMFSKDKTFI 
VRQSIHDEIS VSSMDASRQL MLNEEQLEDM RQELVRQYQE HQQATELLRQ AHMRQMERQR 
EDQEQLQEEI KRLNRQLAQR SSIDNENLVS ERERVLLEEL EALKQLSLAG REKLCCELRN 
SSTQTQNGNE NQGEVEEQTF KEKELDRKPE DVPPEILSNE RYALQKANNR LLKILLEVVK 
TTAAVEETIG RHVLGILDRS SKSQSSASLI WRSEAEASVK SCVHEEHTRV TDESIPSYSG 
SDMPRNDINM WSKVTEEGTE LSQRLVRSGF AGTEIDPENE ELMLNISSRL QAAVEKLLEA 
ISETSSQLEH AKVTQTELMR ESFRQKQEAT ESLKCQEELR ERLHEESRAR EQLAVELSKA 
EGVIDGYADE KTLFERQIQE KTDIIDRLEQ ELLCASNRLQ ELEAEQQQIQ EERELLSRQK 
EAMKAEAGPV EQQLLQETEK LMKEKLEVQC QAEKVRDDLQ KQVKALEIDV EEQVSRFIEL 
EQEKNTELMD LRQQNQALEK QLEKMRKFLD EQAIDREHER DVFQQEIQKL EQQLKVVPRF 
QPISEHQTRE VEQLANHLKE KTDKCSELLL SKEQLQRDIQ ERNEEIEKLE FRVRELEQAL 
LVSADTFQKV EDRKHFGAVE AKPELSLEVQ LQAERDAIDR KEKEITNLEE QLEQFREELE 
NKNEEVQQLH MQLEIQKKES TTRLQELEQE NKLFKDDMEK LGLAIKESDA MSTQDQHVLF 
GKFAQIIQEK EVEIDQLNEQ VTKLQQQLKI TTDNKVIEEK NELIRDLETQ IECLMSDQEC 
VKRNREEEIE QLNEVIEKLQ QELANIGQKT SMNAHSLSEE ADSLKHQLDV VIAEKLALEQ 
QVETANEEMT FMKNVLKETN FKMNQLTQEL FSLKRERESV EKIQSIPENS VNVAIDHLSK 
DKPELEVVLT EDALKSLENQ TYFKSFEENG KGSIINLETR LLQLESTVSA KDLELTQCYK 
QIKDMQEQGQ FETEMLQKKI VNLQKIVEEK VAAALVSQIQ LEAVQEYAKF CQDNQTISSE 
PERTNIQNLN QLREDELGSD ISALTLRISE LESQVVEMHT SLILEKEQVE IAEKNVLEKE 
KKLLELQKLL EGNEKKQREK EKKRSPQDVE VLKTTTELFH SNEESGFFNE LEALRAESVA 
TKAELASYKE KAEKLQEELL VKETNMTSLQ KDLSQVRDHL AEAKEKLSIL EKEDETEVQE 
SKKACMFEPL PIKLSKSIAS QTDGTLKISS SNQTPQILVK NAGIQINLQS ECSSEEVTEI 
ISQFTEKIEK MQELHAAEIL DMESRHISET ETLKREHYVA VQLLKEECGT LKAVIQCLRS 
KEGSSIPELA HSDAYQTREI CSSDSGSDWG QGIYLTHSQG FDIASEGRGE ESESATDSFP 
KKIKGLLRAV HNEGMQVLSL TESPYSDGED HSIQQVSEPW LEERKAYINT ISSLKDLITK 
MQLQREAEVY DSSQSHESFS DWRGELLLAL QQVFLEERSV LLAAFRTELT ALGTTDAVGL 
LNCLEQRIQE QGVEYQAAME CLQKADRRSL LSEIQALHAQ MNGRKITLKR EQESEKPSQE 
LLEYNIQQKQ SQMLEMQVEL SSMKDRATEL QEQLSSEKMV VAELKSELAQ TKLELETTLK 
AQHKHLKELE AFRLEVKDKT DEVHLLNDTL ASEQKKSREL QWALEKEKAK LGRSEERDKE 
ELEDLKFSLE SQKQRNLQLN LLLEQQKQLL NESQQKIESQ RMLYDAQLSE EQGRNLELQV 
LLESEKVRIR EMSSTLDRER ELHAQLQSSD GTGQSRPPLP SEDLLKELQK QLEEKHSRIV 
ELLNETEKYK LDSLQTRQQM EKDRQVHRKT LQTEQEANTE GQKKMHELQS KVEDLQRQLE 
EKRQQVYKLD LEGQRLQGIM QEFQKQELER EEKRESRRIL YQNLNEPTTW SLTSDRTRNW 
VLQQKIEGET KESNYAKLIE MNGGGTGCNH ELEMIRQKLQ CVASKLQVLP QKASERLQFE 
TADDEDFIWV QENIDEIILQ LQKLTGQQGE EPSLVSPSTS CGSLTERLLR QNAELTGHIS 
QLTEEKNDLR NMVMKLEEQI RWYRQTGAGR DNSSRFSLNG GANIEAIIAS EKEVWNREKL 
TLQKSLKRAE AEVYKLKAEL RNDSLLQTLS PDSEHVTLKR IYGKYLRAES FRKALIYQKK 
YLLLLLGGFQ ECEDATLALL ARMGGQPAFT DLEVITNRPK GFTRFRSAVR VSIAISRMKF 
LVRRWHRVTG SVSININRDG FGLNQGAEKT DSFYHSSGGL ELYGEPRHTT YRSRSDLDYI 
RSPLPFQNRY PGTPADFNPG SLACSQLQNY DPDRALTDYI TRLEALQRRL GTIQSGSTTQ 
FHAGMRR

Genular Protein ID: 3144095179

Symbol: Q6PJH3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6PJH3

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 GO 5 IntAct 1 InterPro 1 KEGG 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 PharmGKB 1 ProteomicsDB 1 RefSeq 2 SAM 2 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 314
  • Mass: 36171
  • Checksum: 70D4D3357B87EAEF
  • Sequence:
    • MEDEERQKKL EAGKAKLAQF RQRKAQSDGQ SPSKKQKKKR KTSSSKHDVS AHHDLNIDQS 
QCNEMYINSS QRVESTVIPE STIMRTLHSG EITSHEQGFS VELESEISTT ADDCSSEVNG 
CSFVMRTGKP TNLLREEEFG VDDSYSEQGA QDSPTHLEMM ESELAGKQHE IEELNRELEE 
MRVTYGTEGL QQLQEFEAAI KQRDGIITQL TANLQQARRE KDETMREFLE LTEQSQKLQI 
QFQQLQASET LRNSTHSSTA ADLLQAKQQI LTHQQQLEEQ DHLLEDYQKK KEDFTMQISF 
LQEKIKVYEM VCLF

Genular Protein ID: 859980428

Symbol: Q5GIA7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5GIA7

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 InterPro 1 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 PharmGKB 1 RefSeq 2 SAM 2

Sequence Information:

  • Length: 1016
  • Mass: 118199
  • Checksum: 58C4F432AF444604
  • Sequence:
    • DNENLVSERE RVLLEELEAL KQLSLAGREK LCCELRNSST QTQNGNENQG EVEEQTFKEK 
ELDRKPEDVP PEILSNERYA LQKANNRLLK ILLEVVKTTA AVEETIGRHV LGILDRSSKS 
QSSASLIWRS EAEASVKSCV HEEHTRVTDE SIPSYSGSDM PRNDINMWSK VTEEGTELSQ 
RLVRSGFAGT EIDPENEELM LNISSRLQAA VEKLLEAISE TSSQLEHAKV TQTELMRESF 
RQKQEATESL KCQEELRERL HEESRAREQL AVELSKAEGV IDGYADEKTL FERQIQEKTD 
IIDRLEQELL CASNRLQELE AEQQQIQEER ELLSRQKEAM KAEAGPVEQQ LLQETEKLMK 
EKLEVQCQAE KVRDDLQKQV KALEIDVEEQ VSRFIELEQE KNTELMDLRQ QNQALEKQLE 
KMRKFLDEQA IDREHERDVF QQEIQKLEQQ LKVVPRFQPI SEHQTREVEQ LANHLKEKTD 
KCSELLLSKE QLQRDIQERN EEIEKLEFRV RELEQALLVS ADTFQKVEDR KHFGAVEAKP 
ELSLEVQLQA ERDAIDRKEK EITNLEEQLE QFREELENKN EEVQQLHMQL EIQKKESTTR 
LQELEQENKL FKDDMEKLGL AIKESDAMST QDQHVLFGKF AQIIQEKEVE IDQLNEQVTK 
LQQQLKITTD NKVIEEKNEL IRDLETQIEC LMSDQECVKR NREEEIEQLN EVIEKLQQEL 
ANIGQKTSMN AHSLSEEADS LKHQLDVVIA EKLALEQQVE TANEEMTFMK NVLKETNFKM 
NQLTQELFSL KRERESVEKI QSIPENSVNV AIDHLSKDKP ELEVVLTEDA LKSLENQTYF 
RSFEENGKGS IINLETRLLQ LESTVSAKDL ELTQCYKQIK DMQEQGQFET EMLQKKIVNL 
QKIVEEKVAA ALVSQIQLEA VQEYAKFCQD NQTISSEPER TNIQNLNQLR EDELGSDISA 
LTLRISELES QVVEMHTSLI LEKEQVEIAE KNVLEKEKKL LELQKLLEGN EKKQRE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.