Details for: DDX6

Gene ID: 1656

Symbol: DDX6

Ensembl ID: ENSG00000110367

Description: DEAD-box helicase 6

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 442.7651
    Cell Significance Index: -68.8700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 283.5674
    Cell Significance Index: -71.9300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 168.0813
    Cell Significance Index: -79.3600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 162.5079
    Cell Significance Index: -66.0200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 143.4431
    Cell Significance Index: -73.7900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 69.3171
    Cell Significance Index: -66.1800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 61.0646
    Cell Significance Index: -75.2900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 26.6942
    Cell Significance Index: -71.5100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 20.0124
    Cell Significance Index: -78.9700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 19.8929
    Cell Significance Index: -61.1000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 16.3073
    Cell Significance Index: -35.6900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 4.3703
    Cell Significance Index: 509.3100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.8272
    Cell Significance Index: 117.8800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.7879
    Cell Significance Index: 358.6600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.5607
    Cell Significance Index: 169.7600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.4295
    Cell Significance Index: 257.7000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.3575
    Cell Significance Index: 166.9200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.3095
    Cell Significance Index: 469.6900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.2336
    Cell Significance Index: 74.0600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.1858
    Cell Significance Index: 162.8500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.1385
    Cell Significance Index: 225.9400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.0666
    Cell Significance Index: 65.5600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.9914
    Cell Significance Index: 55.6300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.9861
    Cell Significance Index: 435.9900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.7986
    Cell Significance Index: 436.1500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.7909
    Cell Significance Index: 19.7700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.7801
    Cell Significance Index: 59.8700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.7573
    Cell Significance Index: 89.3100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.6499
    Cell Significance Index: 34.1200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.5825
    Cell Significance Index: 402.8900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.5775
    Cell Significance Index: 15.4200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.5421
    Cell Significance Index: 69.5000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.4547
    Cell Significance Index: 21.2000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4412
    Cell Significance Index: 20.0000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4123
    Cell Significance Index: 11.8800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.3465
    Cell Significance Index: 652.3500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.3193
    Cell Significance Index: 8.6900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.3094
    Cell Significance Index: 19.5000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.3027
    Cell Significance Index: 21.4100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3016
    Cell Significance Index: 8.4300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2415
    Cell Significance Index: 11.3500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.2093
    Cell Significance Index: 15.6000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2092
    Cell Significance Index: 35.7300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2003
    Cell Significance Index: 38.1200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1381
    Cell Significance Index: 87.7100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1267
    Cell Significance Index: 12.5300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1265
    Cell Significance Index: 57.4200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1142
    Cell Significance Index: 210.5400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1091
    Cell Significance Index: 1.8700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0971
    Cell Significance Index: 149.4500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0646
    Cell Significance Index: 8.3500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0455
    Cell Significance Index: 61.8300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.0342
    Cell Significance Index: 0.8200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0204
    Cell Significance Index: -14.9600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0411
    Cell Significance Index: -30.4400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0483
    Cell Significance Index: -2.5100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0681
    Cell Significance Index: -51.5100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0745
    Cell Significance Index: -46.5000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0957
    Cell Significance Index: -53.9700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1165
    Cell Significance Index: -3.3400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1697
    Cell Significance Index: -11.4100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1816
    Cell Significance Index: -18.5600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2069
    Cell Significance Index: -43.5700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2425
    Cell Significance Index: -12.6300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2534
    Cell Significance Index: -36.8400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2694
    Cell Significance Index: -77.5200
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.3800
    Cell Significance Index: -8.7800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.3862
    Cell Significance Index: -13.5700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.4154
    Cell Significance Index: -47.5900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4555
    Cell Significance Index: -20.1500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5250
    Cell Significance Index: -13.8100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5430
    Cell Significance Index: -18.8700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.5540
    Cell Significance Index: -14.2400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.5625
    Cell Significance Index: -11.9800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5672
    Cell Significance Index: -59.0600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.5911
    Cell Significance Index: -67.4700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.6238
    Cell Significance Index: -23.6200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.6534
    Cell Significance Index: -14.1500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.6545
    Cell Significance Index: -8.9300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.6871
    Cell Significance Index: -11.5000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.7349
    Cell Significance Index: -58.2100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.8372
    Cell Significance Index: -16.3400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.9111
    Cell Significance Index: -19.0700
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -1.0171
    Cell Significance Index: -7.8400
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -1.0812
    Cell Significance Index: -23.1100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -1.1703
    Cell Significance Index: -21.6300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -1.2328
    Cell Significance Index: -18.2000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.2441
    Cell Significance Index: -33.3400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.2616
    Cell Significance Index: -77.3500
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -1.2680
    Cell Significance Index: -37.2400
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -1.3775
    Cell Significance Index: -17.0900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -1.4118
    Cell Significance Index: -16.8300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -1.4169
    Cell Significance Index: -40.4400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -1.4307
    Cell Significance Index: -36.5500
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -1.5012
    Cell Significance Index: -9.0700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.5629
    Cell Significance Index: -51.1700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.5698
    Cell Significance Index: -41.9900
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -1.5730
    Cell Significance Index: -14.4900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.5828
    Cell Significance Index: -50.4100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -1.7137
    Cell Significance Index: -86.6000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** DDX6 is a member of the DEAD-box helicase family, characterized by its ability to unwind DNA and RNA double-strands. This protein is highly expressed in various cell types, including immune cells, such as GABAergic neurons, CD8-positive T cells, and B cells. DDX6 is involved in multiple RNA processing pathways, including deadenylation-dependent mRNA decay, mrna binding, and stress granule assembly. **Pathways and Functions:** DDX6 plays a crucial role in regulating mRNA decay, translation, and stress granule assembly. It is involved in the following pathways: 1. **Deadenylation-dependent mRNA decay**: DDX6 facilitates the degradation of mRNAs by 5' to 3' exoribonuclease, regulating gene expression and preventing the accumulation of toxic mRNAs. 2. **mRNA binding**: DDX6 binds to specific mRNAs, modulating their translation and stability. 3. **Stress granule assembly**: DDX6 is involved in the assembly and disassembly of stress granules, which are essential for the regulation of gene expression in response to cellular stress. 4. **Translation regulation**: DDX6 modulates translation by interacting with ribosomes and other translation factors. 5. **Viral RNA genome packaging**: DDX6 has been shown to play a role in the packaging of viral RNAs into particles. **Clinical Significance:** DDX6 has been implicated in various immune-related disorders, including: 1. **Autoimmune diseases**: DDX6 has been shown to be involved in the regulation of immune responses and the development of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. 2. **Cancer**: DDX6 has been implicated in the regulation of gene expression and the development of cancer, particularly in T cell and B cell malignancies. 3. **Neurological disorders**: DDX6 has been linked to neurological disorders, such as Alzheimer's disease and amyotrophic lateral sclerosis (ALS). 4. **Immunodeficiency diseases**: DDX6 has been shown to be involved in the regulation of immune responses and the development of immunodeficiency diseases, such as severe combined immunodeficiency (SCID). In conclusion, DDX6 is a multifunctional protein that plays a crucial role in RNA processing and immune cell function. Its dysregulation has been implicated in various immune-related disorders, highlighting the importance of further research into the mechanisms of DDX6 and its role in human health and disease.

Genular Protein ID: 2198663365

Symbol: DDX6_HUMAN

Name: ATP-dependent RNA helicase p54

UniProtKB Accession Codes:

P26196 Q5D048

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CORUM 1 CTD 1 ChEBI 6 ChEMBL 1 ChiTaRS 1 ComplexPortal 4 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EC 1 EMBL 3 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 24 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 9 PIR 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 Rhea 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1579499

Title: Cloning, expression and localization of an RNA helicase gene from a human lymphoid cell line with chromosomal breakpoint 11q23.3.

PubMed ID: 1579499

DOI: 10.1093/nar/20.8.1967

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1394235

Title: The RCK gene associated with t(11;14) translocation is distinct from the MLL/ALL-1 gene with t(4;11) and t(11;19) translocations.

PubMed ID: 1394235

PubMed ID: 16364915

Title: Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping.

PubMed ID: 16364915

DOI: 10.1016/j.molcel.2005.10.031

PubMed ID: 16699599

Title: Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies.

PubMed ID: 16699599

DOI: 10.1371/journal.ppat.0020041

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 20616046

Title: LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing.

PubMed ID: 20616046

DOI: 10.1073/pnas.0914987107

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22915799

Title: HIV-1 replication and APOBEC3 antiviral activity are not regulated by P bodies.

PubMed ID: 22915799

DOI: 10.1128/jvi.00595-12

PubMed ID: 23209657

Title: Ataxin-2-like is a regulator of stress granules and processing bodies.

PubMed ID: 23209657

DOI: 10.1371/journal.pone.0050134

PubMed ID: 23125361

Title: The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function.

PubMed ID: 23125361

DOI: 10.1093/nar/gks1032

PubMed ID: 26184334

Title: Comprehensive protein interactome analysis of a key RNA helicase: detection of novel stress granule proteins.

PubMed ID: 26184334

DOI: 10.3390/biom5031441

PubMed ID: 26027925

Title: The eIF4E-Binding protein 4E-T is a component of the mRNA decay machinery that bridges the 5' and 3' termini of target mRNAs.

PubMed ID: 26027925

DOI: 10.1016/j.celrep.2015.04.065

PubMed ID: 25995375

Title: P-body assembly requires DDX6 repression complexes rather than decay or Ataxin2/2L complexes.

PubMed ID: 25995375

DOI: 10.1091/mbc.e15-03-0136

PubMed ID: 26098573

Title: A conserved mechanism of TOR-dependent RCK-mediated mRNA degradation regulates autophagy.

PubMed ID: 26098573

DOI: 10.1038/ncb3189

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27342281

Title: The DDX6-4E-T interaction mediates translational repression and P-body assembly.

PubMed ID: 27342281

DOI: 10.1093/nar/gkw565

PubMed ID: 28216671

Title: Dual mechanisms regulate the nucleocytoplasmic localization of human DDX6.

PubMed ID: 28216671

DOI: 10.1038/srep42853

PubMed ID: 30258011

Title: Rotavirus Induces Formation of Remodeled Stress Granules and P Bodies and Their Sequestration in Viroplasms To Promote Progeny Virus Production.

PubMed ID: 30258011

DOI: 10.1128/jvi.01363-18

PubMed ID: 31422817

Title: Rare de novo missense variants in RNA helicase DDX6 cause intellectual disability and dysmorphic features and lead to P-body defects and RNA dysregulation.

PubMed ID: 31422817

DOI: 10.1016/j.ajhg.2019.07.010

PubMed ID: 31439631

Title: Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression.

PubMed ID: 31439631

DOI: 10.1101/gad.329219.119

PubMed ID: 32354837

Title: 4E-T-bound mRNAs are stored in a silenced and deadenylated form.

PubMed ID: 32354837

DOI: 10.1101/gad.336073.119

PubMed ID: 14684915

Title: Crystallization and X-ray analysis of the N-terminal core domain of a tumour-associated human DEAD-box RNA helicase, rck/p54.

PubMed ID: 14684915

DOI: 10.1107/s0907444903024223

PubMed ID: 19285948

Title: Structural basis for the mutually exclusive anchoring of P body components EDC3 and Tral to the DEAD box protein DDX6/Me31B.

PubMed ID: 19285948

DOI: 10.1016/j.molcel.2009.02.014

PubMed ID: 26489469

Title: Structure of a human 4E-T/DDX6/CNOT1 complex reveals the different interplay of DDX6-binding proteins with the CCR4-NOT complex.

PubMed ID: 26489469

DOI: 10.1016/j.celrep.2015.09.033

PubMed ID: 29510985

Title: Molecular architecture of LSM14 interactions involved in the assembly of mRNA silencing complexes.

PubMed ID: 29510985

DOI: 10.15252/embj.201797869

Sequence Information:

  • Length: 483
  • Mass: 54417
  • Checksum: F802C642861793FB
  • Sequence:
    • MSTARTENPV IMGLSSQNGQ LRGPVKPTGG PGGGGTQTQQ QMNQLKNTNT INNGTQQQAQ 
SMTTTIKPGD DWKKTLKLPP KDLRIKTSDV TSTKGNEFED YCLKRELLMG IFEMGWEKPS 
PIQEESIPIA LSGRDILARA KNGTGKSGAY LIPLLERLDL KKDNIQAMVI VPTRELALQV 
SQICIQVSKH MGGAKVMATT GGTNLRDDIM RLDDTVHVVI ATPGRILDLI KKGVAKVDHV 
QMIVLDEADK LLSQDFVQIM EDIILTLPKN RQILLYSATF PLSVQKFMNS HLQKPYEINL 
MEELTLKGVT QYYAYVTERQ KVHCLNTLFS RLQINQSIIF CNSSQRVELL AKKISQLGYS 
CFYIHAKMRQ EHRNRVFHDF RNGLCRNLVC TDLFTRGIDI QAVNVVINFD FPKLAETYLH 
RIGRSGRFGH LGLAINLITY DDRFNLKSIE EQLGTEIKPI PSNIDKSLYV AEYHSEPVED 
EKP

Genular Protein ID: 2970205627

Symbol: B2R858_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2R858

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 9 Gene3D 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 7 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SUPFAM 1

Sequence Information:

  • Length: 472
  • Mass: 53216
  • Checksum: 83AC5228E102ED04
  • Sequence:
    • MGLSSQNGQL RGPVKPTGGP GGGGTQTQQQ MNQLKNTNTI NNGTQQQAQS MTTTIKPGDD 
WKKTLKLPPK DLRIKTSDVT STKGNEFEDY CLKRELLMGI FEMGWEKPSP IQEESIPIAL 
SGRDILARAK NGTGKSGAYL IPLLERLDLK KDNIQAMVIV PTRELALQVS QICIQVSKHM 
GGAKVMATTG GTNLRDDIMR LDDTVHVVIA TPGRILDLIK KGVAKVDHVQ MIVLDEADKL 
LSQDFVQIME DIILTLPKNR QILLYSATFP LSVQKFMNSH LQKPYEINLM EELTLKGVTQ 
YYAYVTERQK VHCLNTLFSR LQINQSIIFC NSSQRVELLA KKISQLGYSC FYIHAKMRQE 
HRNRVFHDFR NGLCRNLVCT DLFTRGIDIQ AVNVVINFDF PKLAETYLHR IGRSGRFGHL 
GLAINLITYD DRFNLKSIEE QLGTEIKPIP SNIDKSLYVA EYHSEPVEDE KP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.