Details for: TIMM8A
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 50.3391
Cell Significance Index: -7.8300 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 30.4759
Cell Significance Index: -7.7300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 8.3864
Cell Significance Index: -10.3400 - Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 3.8130
Cell Significance Index: 11.3400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 3.4754
Cell Significance Index: -9.3100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 2.7800
Cell Significance Index: -10.9700 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.3530
Cell Significance Index: 133.8400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.3141
Cell Significance Index: 78.8900 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.0474
Cell Significance Index: 113.9300 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.8430
Cell Significance Index: 761.2000 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 0.7950
Cell Significance Index: -1.7400 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.7449
Cell Significance Index: 121.1500 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.7227
Cell Significance Index: 19.6700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.5113
Cell Significance Index: 35.3600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.5024
Cell Significance Index: 26.1000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.4421
Cell Significance Index: 20.0400 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 0.4172
Cell Significance Index: 3.4500 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.3888
Cell Significance Index: 10.4000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3808
Cell Significance Index: 207.9900 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.3699
Cell Significance Index: 26.1600 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.3276
Cell Significance Index: 4.4700 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2964
Cell Significance Index: 131.0400 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.2824
Cell Significance Index: 3.0700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2754
Cell Significance Index: 7.9400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.2363
Cell Significance Index: 46.9000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.2231
Cell Significance Index: 26.3100 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.2186
Cell Significance Index: 28.2400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.2091
Cell Significance Index: 25.7100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.2063
Cell Significance Index: 28.3300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.2021
Cell Significance Index: 12.7400 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.1795
Cell Significance Index: 13.3800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.1758
Cell Significance Index: 5.6300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1694
Cell Significance Index: 32.2400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.1653
Cell Significance Index: 7.7700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.1634
Cell Significance Index: 3.5400 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.1575
Cell Significance Index: 1.6300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.1482
Cell Significance Index: 9.5600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1273
Cell Significance Index: 22.9400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.1036
Cell Significance Index: 5.4400 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.0991
Cell Significance Index: 2.8400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0987
Cell Significance Index: 4.6000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0896
Cell Significance Index: 2.2400 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.0871
Cell Significance Index: 0.9900 - Cell Name: germ cell (CL0000586)
Fold Change: 0.0834
Cell Significance Index: 0.6300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.0767
Cell Significance Index: 8.7900 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0671
Cell Significance Index: 13.4600 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.0647
Cell Significance Index: 2.2500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.0542
Cell Significance Index: 1.1400 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.0536
Cell Significance Index: 1.4100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0498
Cell Significance Index: 1.3300 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0403
Cell Significance Index: 5.1600 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.0313
Cell Significance Index: 0.2500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0200
Cell Significance Index: 0.5600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0180
Cell Significance Index: 1.3900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0169
Cell Significance Index: 0.3600 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.0152
Cell Significance Index: 0.4400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0112
Cell Significance Index: 4.0300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0048
Cell Significance Index: 0.1700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0011
Cell Significance Index: 0.8500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0004
Cell Significance Index: 0.3000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0022
Cell Significance Index: -4.1300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0057
Cell Significance Index: -10.4900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0064
Cell Significance Index: -9.9100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0082
Cell Significance Index: -11.2100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0117
Cell Significance Index: -8.6900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0131
Cell Significance Index: -8.3300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0144
Cell Significance Index: -1.4700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0171
Cell Significance Index: -9.6500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0182
Cell Significance Index: -8.2600 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.0184
Cell Significance Index: -0.4700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0197
Cell Significance Index: -3.3700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0206
Cell Significance Index: -12.8800 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: -0.0285
Cell Significance Index: -0.2200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0388
Cell Significance Index: -11.1700 - Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: -0.0465
Cell Significance Index: -0.4000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0476
Cell Significance Index: -6.9200 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0517
Cell Significance Index: -6.0200 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.0517
Cell Significance Index: -0.8700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0554
Cell Significance Index: -11.6700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0713
Cell Significance Index: -4.3700 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.0719
Cell Significance Index: -1.2700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0802
Cell Significance Index: -4.9300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0991
Cell Significance Index: -7.8500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1031
Cell Significance Index: -10.7300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1099
Cell Significance Index: -7.3900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1130
Cell Significance Index: -6.3400 - Cell Name: peg cell (CL4033014)
Fold Change: -0.1160
Cell Significance Index: -2.6800 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.1260
Cell Significance Index: -1.8600 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.1269
Cell Significance Index: -0.8600 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.1398
Cell Significance Index: -1.3300 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1464
Cell Significance Index: -2.4500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1891
Cell Significance Index: -8.3700 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: -0.1954
Cell Significance Index: -2.0400 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.1969
Cell Significance Index: -5.8000 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.2085
Cell Significance Index: -1.9200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.2250
Cell Significance Index: -8.5200 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.2275
Cell Significance Index: -8.3500 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: -0.2423
Cell Significance Index: -3.4000 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.2458
Cell Significance Index: -8.6100 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: -0.2471
Cell Significance Index: -2.1000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1638675486
Symbol: TIM8A_HUMAN
Name: Mitochondrial import inner membrane translocase subunit Tim8 A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8841189
Title: A novel X-linked gene, DDP, shows mutations in families with deafness (DFN-1), dystonia, mental deficiency and blindness.
PubMed ID: 8841189
DOI: 10.1038/ng1096-177
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15772651
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10051608
Title: Human deafness dystonia syndrome is a mitochondrial disease.
PubMed ID: 10051608
PubMed ID: 10051550
Title: Mitochondria and dystonia: the movement disorder connection?
PubMed ID: 10051550
PubMed ID: 11489896
Title: Role of the deafness dystonia peptide 1 (DDP1) in import of human Tim23 into the inner membrane of mitochondria.
PubMed ID: 11489896
PubMed ID: 15254020
Title: The calcium-binding aspartate/glutamate carriers, citrin and aralar1, are new substrates for the DDP1/TIMM8a-TIMM13 complex.
PubMed ID: 15254020
DOI: 10.1093/hmg/ddh217
PubMed ID: 11803487
Title: Neuronal cell death in the visual cortex is a prominent feature of the X-linked recessive mitochondrial deafness-dystonia syndrome caused by mutations in the TIMM8a gene.
PubMed ID: 11803487
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 10878669
Title: A de novo missense mutation in a critical domain of the X-linked DDP gene causes the typical deafness-dystonia-optic atrophy syndrome.
PubMed ID: 10878669
PubMed ID: 11875042
Title: Human deafness dystonia syndrome is caused by a defect in assembly of the DDP1/TIMM8a-TIMM13 complex.
PubMed ID: 11875042
DOI: 10.1093/hmg/11.5.477
PubMed ID: 11956200
Title: The C66W mutation in the deafness dystonia peptide 1 (DDP1) affects the formation of functional DDP1.TIM13 complexes in the mitochondrial intermembrane space.
PubMed ID: 11956200
Sequence Information:
- Length: 97
- Mass: 10998
- Checksum: CB72822290F20AB0
- Sequence:
MDSSSSSSAA GLGAVDPQLQ HFIEVETQKQ RFQQLVHQMT ELCWEKCMDK PGPKLDSRAE ACFVNCVERF IDTSQFILNR LEQTQKSKPV FSESLSD
Genular Protein ID: 3783318397
Symbol: A0A2R8YDA8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 15772651
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 48
- Mass: 5316
- Checksum: 242BC60C9FF2B426
- Sequence:
MDSSSSSSAA GLGAVDPQLQ HFIEVETQKQ RFQQLVHQMT ELCWVPVA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.