Details for: DOCK1

Gene ID: 1793

Symbol: DOCK1

Ensembl ID: ENSG00000150760

Description: dedicator of cytokinesis 1

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 4.03
    Marker Score: 3570
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 3.97
    Marker Score: 4502
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 3.66
    Marker Score: 3161
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 3.29
    Marker Score: 2538.5
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 3.19
    Marker Score: 2218
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 3.17
    Marker Score: 3835
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 3.11
    Marker Score: 5979.5
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 3.01
    Marker Score: 1584
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 2.98
    Marker Score: 857.5
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.95
    Marker Score: 62862
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 2.88
    Marker Score: 6899
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 2.83
    Marker Score: 11801.5
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 2.78
    Marker Score: 1547
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 2.77
    Marker Score: 1654
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 2.74
    Marker Score: 3410
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 2.67
    Marker Score: 3587
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.64
    Marker Score: 3037
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.57
    Marker Score: 1500
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 2.53
    Marker Score: 2080
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.49
    Marker Score: 2370
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 2.27
    Marker Score: 1495
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2.25
    Marker Score: 2480
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 2.16
    Marker Score: 1419
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.13
    Marker Score: 8924
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.13
    Marker Score: 1247
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 2.12
    Marker Score: 769
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 2.09
    Marker Score: 2587
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 2.03
    Marker Score: 1139
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 2.02
    Marker Score: 1095
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 2.02
    Marker Score: 2174
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2
    Marker Score: 584
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.96
    Marker Score: 31417
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 1.94
    Marker Score: 2820
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.89
    Marker Score: 1057
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.86
    Marker Score: 482
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.85
    Marker Score: 1601
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.84
    Marker Score: 582
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 1.83
    Marker Score: 800
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 1.83
    Marker Score: 5245
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.82
    Marker Score: 901
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.81
    Marker Score: 3973
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.79
    Marker Score: 660
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.68
    Marker Score: 5983
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 1.68
    Marker Score: 532
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.68
    Marker Score: 632
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.6
    Marker Score: 500
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.58
    Marker Score: 1692
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.57
    Marker Score: 3198
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.56
    Marker Score: 396
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.54
    Marker Score: 3627
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.46
    Marker Score: 1758
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.42
    Marker Score: 2009
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.41
    Marker Score: 12371
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 1.4
    Marker Score: 283
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.36
    Marker Score: 510
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.33
    Marker Score: 1352
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 1.32
    Marker Score: 2589
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.28
    Marker Score: 434
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.24
    Marker Score: 744
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.24
    Marker Score: 19347
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 1.21
    Marker Score: 684
  • Cell Name: basal cell (CL0000646)
    Fold Change: 1.2
    Marker Score: 1552
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 1.2
    Marker Score: 847.5
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.18
    Marker Score: 3162
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 1.17
    Marker Score: 322
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.16
    Marker Score: 7490
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.14
    Marker Score: 1199
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.14
    Marker Score: 552
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.12
    Marker Score: 4143
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 1.11
    Marker Score: 293
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 1.11
    Marker Score: 995
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.07
    Marker Score: 4636
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 1.04
    Marker Score: 6248
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 1.03
    Marker Score: 3373
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 1.02
    Marker Score: 528
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 1.01
    Marker Score: 1072
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.01
    Marker Score: 674
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 1
    Marker Score: 475
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71737
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47961
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30399
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.98
    Marker Score: 5260
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.97
    Marker Score: 502
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.97
    Marker Score: 457
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 0.96
    Marker Score: 908
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.95
    Marker Score: 228
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2407
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 0.94
    Marker Score: 20944
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 0.93
    Marker Score: 1704
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 0.93
    Marker Score: 341
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.93
    Marker Score: 1513
  • Cell Name: club cell (CL0000158)
    Fold Change: 0.93
    Marker Score: 1085
  • Cell Name: bronchial epithelial cell (CL0002328)
    Fold Change: 0.92
    Marker Score: 243
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.91
    Marker Score: 2082
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.91
    Marker Score: 838
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 0.91
    Marker Score: 567
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2721
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 0.91
    Marker Score: 1652
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.9
    Marker Score: 3109
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9
    Marker Score: 324

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Other Information

**Key characteristics:** - DOCK1 is a transmembrane protein that is composed of 12 extracellular domain repeats. - It is expressed in a variety of cell types, including epithelial cells, immune cells, and germ cells. - It is a key regulator of cell migration and invasion, and it is also involved in the regulation of cell cycle progression and apoptosis. **Pathways and functions:** - DOCK1 is involved in the regulation of cytokinesis. - It is a key regulator of cell migration and invasion. - It is also involved in the regulation of cell cycle progression and apoptosis. **Clinical significance:** - Mutations in DOCK1 have been linked to a number of human diseases, including cancer and cardiovascular disease. - Targeting DOCK1 has been investigated as a therapeutic strategy for these diseases. **Additional information:** - DOCK1 is a member of the Dock family of cell adhesion molecules. - It is expressed in high levels in the basal epithelial cells of the prostate and the lens epithelium. - It is also expressed in low levels in the epithelial cells of the trachea and the small intestine. - DOCK1 is a key regulator of cell migration and invasion in vitro. - It is also involved in the regulation of cell cycle progression and apoptosis in vitro.

Genular Protein ID: 1566377129

Symbol: DOCK1_HUMAN

Name: Dedicator of cytokinesis protein 1

UniProtKB Accession Codes:

Q14185 A9Z1Z5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 EPD 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 19 Gene3D 5 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 16 KEGG 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PRO 1 PROSITE 3 PROSITE-ProRule 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 6 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 9 RefSeq 1 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8657152

Title: DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane.

PubMed ID: 8657152

DOI: 10.1128/mcb.16.4.1770

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 8662907

Title: Interaction between the amino-terminal SH3 domain of CRK and its natural target proteins.

PubMed ID: 8662907

DOI: 10.1074/jbc.271.24.14468

PubMed ID: 9808620

Title: Activation of Rac1 by a Crk SH3-binding protein, DOCK180.

PubMed ID: 9808620

DOI: 10.1101/gad.12.21.3331

PubMed ID: 11240126

Title: Identification and kinetic analysis of the interaction between Nck-2 and DOCK180.

PubMed ID: 11240126

DOI: 10.1016/s0014-5793(01)02195-0

PubMed ID: 11171081

Title: Membrane recruitment of DOCK180 by binding to PtdIns(3,4,5)P3.

PubMed ID: 11171081

DOI: 10.1042/0264-6021:3540073

PubMed ID: 12134158

Title: Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex.

PubMed ID: 12134158

DOI: 10.1038/ncb824

PubMed ID: 12432077

Title: Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

PubMed ID: 12432077

DOI: 10.1242/jcs.00219

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19004829

Title: DOCK5 and DOCK1 regulate Caco-2 intestinal epithelial cell spreading and migration on collagen IV.

PubMed ID: 19004829

DOI: 10.1074/jbc.m808010200

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1865
  • Mass: 215346
  • Checksum: 940C5AFD047EBEDE
  • Sequence:
    • MTRWVPTKRE EKYGVAFYNY DARGADELSL QIGDTVHILE TYEGWYRGYT LRKKSKKGIF 
PASYIHLKEA IVEGKGQHET VIPGDLPLIQ EVTTTLREWS TIWRQLYVQD NREMFRSVRH 
MIYDLIEWRS QILSGTLPQD ELKELKKKVT AKIDYGNRIL DLDLVVRDED GNILDPELTS 
TISLFRAHEI ASKQVEERLQ EEKSQKQNID INRQAKFAAT PSLALFVNLK NVVCKIGEDA 
EVLMSLYDPV ESKFISENYL VRWSSSGLPK DIDRLHNLRA VFTDLGSKDL KREKISFVCQ 
IVRVGRMELR DNNTRKLTSG LRRPFGVAVM DVTDIINGKV DDEDKQHFIP FQPVAGENDF 
LQTVINKVIA AKEVNHKGQG LWVTLKLLPG DIHQIRKEFP HLVDRTTAVA RKTGFPEIIM 
PGDVRNDIYV TLVQGDFDKG SKTTAKNVEV TVSVYDEDGK RLEHVIFPGA GDEAISEYKS 
VIYYQVKQPR WFETVKVAIP IEDVNRSHLR FTFRHRSSQD SKDKSEKIFA LAFVKLMRYD 
GTTLRDGEHD LIVYKAEAKK LEDAATYLSL PSTKAELEEK GHSATGKSMQ SLGSCTISKD 
SFQISTLVCS TKLTQNVDLL GLLKWRSNTS LLQQNLRQLM KVDGGEVVKF LQDTLDALFN 
IMMENSESET FDTLVFDALV FIIGLIADRK FQHFNPVLET YIKKHFSATL AYTKLTKVLK 
NYVDGAEKPG VNEQLYKAMK ALESIFKFIV RSRILFNQLY ENKGEADFVE SLLQLFRSIN 
DMMSSMSDQT VRVKGAALKY LPTIVNDVKL VFDPKELSKM FTEFILNVPM GLLTIQKLYC 
LIEIVHSDLF TQHDCREILL PMMTDQLKYH LERQEDLEAC CQLLSHILEV LYRKDVGPTQ 
RHVQIIMEKL LRTVNRTVIS MGRDSELIGN FVACMTAILR QMEDYHYAHL IKTFGKMRTD 
VVDFLMETFI MFKNLIGKNV YPFDWVIMNM VQNKVFLRAI NQYADMLNKK FLDQANFELQ 
LWNNYFHLAV AFLTQESLQL ENFSSAKRAK ILNKYGDMRR QIGFEIRDMW YNLGQHKIKF 
IPEMVGPILE MTLIPETELR KATIPIFFDM MQCEFHSTRS FQMFENEIIT KLDHEVEGGR 
GDEQYKVLFD KILLEHCRKH KYLAKTGETF VKLVVRLMER LLDYRTIMHD ENKENRMSCT 
VNVLNFYKEI EREEMYIRYL YKLCDLHKEC DNYTEAAYTL LLHAKLLKWS EDVCVAHLTQ 
RDGYQATTQG QLKEQLYQEI IHYFDKGKMW EEAIALGKEL AEQYENEMFD YEQLSELLKK 
QAQFYENIVK VIRPKPDYFA VGYYGQGFPT FLRGKVFIYR GKEYERREDF EARLLTQFPN 
AEKMKTTSPP GDDIKNSPGQ YIQCFTVKPK LDLPPKFHRP VSEQIVSFYR VNEVQRFEYS 
RPIRKGEKNP DNEFANMWIE RTIYTTAYKL PGILRWFEVK SVFMVEISPL ENAIETMQLT 
NDKINSMVQQ HLDDPSLPIN PLSMLLNGIV DPAVMGGFAN YEKAFFTDRY LQEHPEAHEK 
IEKLKDLIAW QIPFLAEGIR IHGDKVTEAL RPFHERMEAC FKQLKEKVEK EYGVRIMPSS 
LDDRRGSRPR SMVRSFTMPS SSRPLSVASV SSLSSDSTPS RPGSDGFALE PLLPKKMHSR 
SQDKLDKDDL EKEKKDKKKE KRNSKHQEIF EKEFKPTDIS LQQSEAVILS ETISPLRPQR 
PKSQVMNVIG SERRFSVSPS SPSSQQTPPP VTPRAKLSFS MQSSLELNGM TGADVADVPP 
PLPLKGSVAD YGNLMENQDL LGSPTPPPPP PHQRHLPPPL PSKTPPPPPP KTTRKQASVD 
SGIVQ

Genular Protein ID: 3138519469

Symbol: A0A2X0U2H5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A2X0U2H5

Database IDs:

ARBA 4 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 3 Gene3D 5 InterPro 16 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 6 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 6 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 2

Sequence Information:

  • Length: 1865
  • Mass: 215376
  • Checksum: 840D5AFD047EBEDE
  • Sequence:
    • MTRWVPTKRE EKYGVAFYNY DARGADELSL QIGDTVHILE TYEGWYRGYT LRKKSKKGIF 
PASYIHLKEA IVEGKGQHET VIPGDLPLIQ EVTTTLREWS TIWRQLYVQD NREMFRSVRH 
MIYDLIEWRS QILSGTLPQD ELKELKKKVT AKIDYGNRIL DLDLVVRDED GNILDPELTS 
TISLFRAHEI ASKQVEERLQ EEKSQKQNID INRQAKFAAT PSLALFVNLK NVVCKIGEDA 
EVLMSLYDPV ESKFISENYL VRWSSSGLPK DIDRLHNLRA VFTDLGSKDL KREKISFVCQ 
IVRVGRMELR DNNTRKLTSG LRRPFGVAVM DVTDIINGKV DDEDKQHFIP FQPVAGENDF 
LQTVINKVIA AKEVNHKGQG LWVTLKLLPG DIHQIRKEFP HLVDRTTAVA RKTGFPEIIM 
PGDVRNDIYV TLVQGDFDKG SKTTAKNVEV TVSVYDEDGK RLEHVIFPGA GDEAISEYKS 
VIYYQVKQPR WFETVKVAIP IEDVNRSHLR FTFRHRSSQD SKDKSEKIFA LAFVKLMRYD 
GTTLRDGEHD LIVYKAEAKK LEDAATYLSL PSTKAELEEK GHSATGKSMQ SLGSCTISKD 
SFQISTLVCS TKLTQNVDLL GLLKWRSNTS LLQQNLRQLM KVDGGEVVKF LQDTLDALFN 
IMMENSESET FDTLVFDALV FIIGLIADRK FQHFNPVLET YIKKHFSATL AYTKLTKVLK 
NYVDGAEKPG VNEQLYKAMK ALESIFKFIV RSRILFNQLY ENKGEADFVE SLLQLFRSIN 
DMMSSMSDQT VRVKGAALKY LPTIVNDVKL VFDPKELSKM FTEFILNVPM GLLTIQKLYC 
LIEIVHSDLF TQHDCREILL PMMTDQLKYH LERQEDLEAC CQLLSHILEV LYRKDVGPTQ 
RHVQIIMEKL LRTVNRTVIS MGRDSELIGN FVACMTAILR QMEDYHYAHL IKTFGKMRTD 
VVDFLMETFI MFKNLIGKNV YPFDWVIMNM VQNKVFLRAI NQYADMLNKK FLDQANFELQ 
LWNNYFHLAV AFLTQESLQL ENFSSAKRAK ILNKYGDMRR QIGFEIRDMW YNLGQHKIKF 
IPEMVGPILE MTLIPETELR KATIPIFFDM MQCEFHSTRS FQMFENEIIT KLDHEVEGGR 
GDEQYKVLFD KILLEHCRKH KYLAKTGETF VKLVVRLMER LLDYRTIMHD ENKENRMSCT 
VNVLNFYKEI EREEMYIRYL YKLCDLHKEC DNYTEAAYTL LLHAKLLKWS EDVCVAHLTQ 
RDGYQATTQG QLKEQLYQEI IHYFDKGKMW EEAIALGKEL AEQYENEMFD YEQLSELLKK 
QAQFYENIVK VIRPKPDYFA VGYYGQGFPT FLRGKVFIYR GKEYERREDF EARLLTQFPN 
AEKMKTTSPP GDDIKNSPGQ YIQCFTVKPK LDLPPKFHRP VSEQIVSFYR VNEVQRFEYS 
RPIRKGEKNP DNEFANMWIE RTIYTTAYKL PGILRWFEVK SVFMVEISPL ENAIETMQLT 
NDKINSMVQQ HLDDPSLPIN PLSMLLNGIV DPAVMGGFAN YEKAFFTDRY LQEHPEAHEK 
IEKLKDLIAW QIPFLAEGIR IHGDKVTEAL RPFHERMEAC FKQLKEKVEK EYGVRIMPSS 
LDDRRGSRPR SMVRSFTMPS SSRPLSVASV SSLSSDSTPS RPGSDGFALE PLLPKKMHSR 
SQDKLDKDDL EKEKKDKKKE KRNSKHQEIF EKEFKPTDIS LQQSEAVILS ETISPLRPQR 
PKSQVMNVIG SERRFSVSPS SPSSQQTPPP VTPRAKLSFS MQSSLELNGM TGADVADVPP 
PLPLKGSVAD YGNLMENQDL LGSPTPPPPP PHQRHLPPPL PSKTPPPPPP KTTRKQTSVD 
SGIVQ

Genular Protein ID: 1000778939

Symbol: B2RUU3_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2RUU3

Database IDs:

ARBA 4 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 3 Gene3D 5 GenomeRNAi 1 InterPro 16 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 6 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 6 RefSeq 2 SAM 2 SMART 1 SUPFAM 2

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1865
  • Mass: 215377
  • Checksum: 8DBC33E2226EF4E8
  • Sequence:
    • MTRWVPTKRE EKYGVAFYNY DARGADELSL QIGDTVHILE TYEGWYRGYT LRKKSKKGIF 
PASYIHLKEA IVEGKGQHET VIPGDLPLIQ EVTTTLREWS TIWRQLYVQD NREMFRSVRH 
MIYDLIEWRS QILSGTLPQD ELKELKKKVT AKIDYGNRIL DLDLVVRDED GNILDPELTS 
TISLFRAHEI ASKQVEERLQ EEKSQKQNID INRQAKFAAT PSLALFVNLK NVVCKIGEDA 
EVLMSLYDPV ESKFISENYL VRWSSSGLPK DIDRLHNLRA VFTDLGSKDL KREKISFVCQ 
IVRVGRMELR DNNTRKLTSG LRRPFGVAVM DVTDIINGKV DDEDKQHFIP FQPVAGENDF 
LQTVINKVIA AKEVNHKGQG LWVTLKLLPG DIHQIRKEFP HLVDRTTAVA RKTGFPEIIM 
PGDVRNDIYV TLVQGDFDKG SKTTAKNVEV TVSVYDEDGK RLEHVIFPGA GDEAISEYKS 
VIYYQVKQPR WFETVKVAIP IEDVNRSHLR FTFRHRSSQD SKDKSEKIFA LAFVKLMRYD 
GTTLRDGEHD LIVYKAEAKK LEDAATYLSL PSTKAELEEK GHSATGKSMQ SLGSCTISKD 
SFQISTLVCS TKLTQNVDLL GLLKWRSNTS LLQQNLRQLM KVDGGEVVKF LQDTLDALFN 
IMMENSESET FDTLVFDALV FIIGLIADRK FQHFNPVLET YIKKHFSATL AYTKLTKVLK 
NYVDGAEKPG VNEQLYKAMK ALESIFKFIV RSRILFNQLY ENKGEADFVE SLLQLFRSIN 
DMMSSMSDQT VRVKGAALKY LPTIVNDVKL VFDPKELSKM FTEFILNVPM GLLTIQKLYC 
LIEIVHSDLF TQHDCREILL PMMTDQLKYH LERQEDLEAC CQLLSHILEV LYRKDVGPTQ 
RHVQIIMEKL LRTVNRTVIS MGRDSELIGN FVACMTAILR QMEDYHYAHL IKTFGKMRTD 
VVDFLMETFI MFKNLIGKNV YPFDWVIMNM VQNKVFLRAI NQYADMLNKK FLDQANFELQ 
LWNNYFHLAV AFLTQESLQL ENFSSAKRAK ILNKYGDMRR QIGFEIRDMW YNLGQHKIKF 
IPEMVGPILE MTLIPETELR KATIPIFFDM MQCEFHSTRS FQMFENEIIT KLDHEVEGGR 
GDEQYKVLFD KILLEHCRKH KYLAKTGETF VKLVVRLMER LLDYRTIMHD ENKENRMSCT 
VNVLDFYKEI EREEMYIRYL YKLCDLHKEC DNYTEAAYTL LLHAKLLKWS EDVCVAHLTQ 
RDGYQATTQG QLKEQLYQEI IHYFDKGKMW EEAIALGKEL AEQYENEMFD YEQLSELLKK 
QAQFYENIVK VIRPKPDYFA VGYYGQGFPT FLRGKVFIYR GKEYERREDF EARLLTQFPN 
AEKMKTTSPP GDDIKNSPGQ YIQCFTVKPK LDLPPKFHRP VSEQIVSFYR VNEVQRFEYS 
RPIRKGEKNP DNEFANMWIE RTIYTTAYKL PGILRWFEVK SVFMVEISPL ENAIETMQLT 
NDKINSMVQQ HLDDPSLPIN PLSMLLNGIV DPAVMGGFAN YEKAFFTDRY LQEHPEAHEK 
IEKLKDLIAW QIPFLAEGIR IHGDKVTEAL RPFHERMEAC FKQLKEKVEK EYGVRIMPSS 
LDDRRGSRPR SMVRSFTMPS SSRPLSVASV SSLSSDSTPS RPGSDGFALE PLLPKKMHSR 
SQDKLDKDDL EKEKKDKKKE KRNSKHQEIF EKEFKPTDIS LQQSEAVILS ETISPLRPQR 
PKSQVMNVIG SERRFSVSPS SPSSQQTPPP VTPRAKLSFS MQSSLELNGM TGADVADVPP 
PLPLKGSVAD YGNLMENQDL LGSPTPPPPP PHQRHLPPPL PSKTPPPPPP KTTRKQTSVD 
SGIVQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.