Details for: DPYSL2

Gene ID: 1808

Symbol: DPYSL2

Ensembl ID: ENSG00000092964

Description: dihydropyrimidinase like 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 721.0122
    Cell Significance Index: -112.1500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 438.3320
    Cell Significance Index: -111.1800
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 264.9852
    Cell Significance Index: -109.1600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 203.1226
    Cell Significance Index: -82.5200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 194.7179
    Cell Significance Index: -100.1600
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 163.3776
    Cell Significance Index: -109.6300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 91.2523
    Cell Significance Index: -112.5100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 86.8454
    Cell Significance Index: -82.9200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 38.6134
    Cell Significance Index: -103.4400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 36.0985
    Cell Significance Index: -110.8800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 28.5551
    Cell Significance Index: -112.6800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 20.5246
    Cell Significance Index: -44.9200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 3.0641
    Cell Significance Index: 188.3400
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 3.0439
    Cell Significance Index: 48.8400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.8342
    Cell Significance Index: 568.5300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.5376
    Cell Significance Index: 910.2000
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 2.0661
    Cell Significance Index: 49.5500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.0219
    Cell Significance Index: 105.3200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.8886
    Cell Significance Index: 1306.2000
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 1.6996
    Cell Significance Index: 13.1000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.5005
    Cell Significance Index: 84.2000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.4186
    Cell Significance Index: 194.8100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.2709
    Cell Significance Index: 66.7300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.9816
    Cell Significance Index: 106.7700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.7778
    Cell Significance Index: 52.3000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.7076
    Cell Significance Index: 962.1100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.6685
    Cell Significance Index: 1232.9700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.6171
    Cell Significance Index: 272.8600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.5046
    Cell Significance Index: 22.3200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.4544
    Cell Significance Index: 699.5000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.4112
    Cell Significance Index: 11.7400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4002
    Cell Significance Index: 39.5900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.3810
    Cell Significance Index: 6.5300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.3687
    Cell Significance Index: 13.9600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2858
    Cell Significance Index: 538.1400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1142
    Cell Significance Index: 22.6700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1078
    Cell Significance Index: 68.4800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.0495
    Cell Significance Index: 1.4200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0341
    Cell Significance Index: 6.4800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0226
    Cell Significance Index: -12.3500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0376
    Cell Significance Index: -28.4500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0548
    Cell Significance Index: -40.6100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0611
    Cell Significance Index: -38.1300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0784
    Cell Significance Index: -11.4000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.0931
    Cell Significance Index: -5.5900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.1102
    Cell Significance Index: -80.8100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1298
    Cell Significance Index: -5.8900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1475
    Cell Significance Index: -83.1800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.1569
    Cell Significance Index: -4.5200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1802
    Cell Significance Index: -23.1000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1865
    Cell Significance Index: -84.6500
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.2229
    Cell Significance Index: -4.3500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.2314
    Cell Significance Index: -41.7100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2588
    Cell Significance Index: -54.5000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.3242
    Cell Significance Index: -93.2700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.4092
    Cell Significance Index: -8.9600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.4853
    Cell Significance Index: -82.8600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.4937
    Cell Significance Index: -50.4300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.5043
    Cell Significance Index: -23.7000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.5210
    Cell Significance Index: -64.0600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.5415
    Cell Significance Index: -63.1100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.5721
    Cell Significance Index: -67.4700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.5767
    Cell Significance Index: -74.5100
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.6379
    Cell Significance Index: -6.6500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.6426
    Cell Significance Index: -41.4600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.6681
    Cell Significance Index: -108.6700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.7015
    Cell Significance Index: -53.8300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.7647
    Cell Significance Index: -87.6100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.8569
    Cell Significance Index: -97.8100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.9630
    Cell Significance Index: -100.2700
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -1.0137
    Cell Significance Index: -12.6400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.1369
    Cell Significance Index: -90.0400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.2108
    Cell Significance Index: -38.7800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.2466
    Cell Significance Index: -78.5700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -1.2638
    Cell Significance Index: -94.1900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -1.3054
    Cell Significance Index: -14.8300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -1.4115
    Cell Significance Index: -99.8300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -1.5153
    Cell Significance Index: -25.3600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.5911
    Cell Significance Index: -55.2900
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -1.5965
    Cell Significance Index: -20.1500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -1.6199
    Cell Significance Index: -45.2700
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -1.6981
    Cell Significance Index: -18.5000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.6998
    Cell Significance Index: -55.6500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.7585
    Cell Significance Index: -107.8200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.8045
    Cell Significance Index: -57.4700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -1.8047
    Cell Significance Index: -38.5800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.8168
    Cell Significance Index: -39.3600
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -1.8475
    Cell Significance Index: -36.5300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.9430
    Cell Significance Index: -57.2300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -1.9609
    Cell Significance Index: -52.3600
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -2.0300
    Cell Significance Index: -37.5200
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -2.0710
    Cell Significance Index: -29.7400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -2.0865
    Cell Significance Index: -108.3900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -2.0957
    Cell Significance Index: -44.4800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -2.0959
    Cell Significance Index: -53.8800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -2.1169
    Cell Significance Index: -98.7000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -2.2519
    Cell Significance Index: -78.8900
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -2.2631
    Cell Significance Index: -39.1300
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -2.3064
    Cell Significance Index: -46.3100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -2.4539
    Cell Significance Index: -52.2600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** DPYSL2 is a gene that exhibits a wide range of expression patterns across various cell types, including: 1. **Dihydropyrimidinase-like activity:** DPYSL2 possesses dihydropyrimidinase-like activity, which is crucial for the degradation of pyrimidine nucleobases. 2. **Axon guidance:** DPYSL2 plays a significant role in axon guidance, a process that is essential for the development and formation of neural connections. 3. **Cell differentiation:** DPYSL2 is involved in cell differentiation, a process that is critical for the development and maturation of neural cells. 4. **Cytoskeleton organization:** DPYSL2 regulates cytoskeleton organization, which is essential for maintaining cell shape and structure. **Pathways and Functions:** DPYSL2 is involved in several key pathways, including: 1. **Sema3a signaling:** DPYSL2 interacts with semaphorin 3A (Sema3a) to regulate axon guidance and neural development. 2. **Crmps in sema3a signaling:** DPYSL2 forms complexes with Crmps (crystallin-related protein) to modulate Sema3a signaling. 3. **Cytoskeleton organization:** DPYSL2 regulates microtubule dynamics and cytoskeleton organization, which is essential for maintaining cell shape and structure. 4. **Endocytosis:** DPYSL2 is involved in endocytosis, a process that is critical for regulating the uptake and degradation of cellular components. **Clinical Significance:** The DPYSL2 gene has been implicated in various neurological disorders, including: 1. **Neurodevelopmental disorders:** DPYSL2 has been associated with neurodevelopmental disorders, such as autism spectrum disorder and schizophrenia. 2. **Neurodegenerative diseases:** DPYSL2 has been implicated in neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. 3. **Cancer:** DPYSL2 has been linked to cancer, particularly in the context of glioblastoma and other brain tumors. In conclusion, the DPYSL2 gene is a complex and multifaceted gene that plays a critical role in various cellular processes, including axon guidance, cell differentiation, and cytoskeleton organization. Its significance in neurological disorders and cancer highlights the need for further research into the molecular mechanisms underlying DPYSL2 function.

Genular Protein ID: 3287207709

Symbol: DPYL2_HUMAN

Name: Dihydropyrimidinase-related protein 2

UniProtKB Accession Codes:

Q16555 A8K5H2 B4DR31 D3DSS7 O00424

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CPTAC 2 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 DrugCentral 1 EMBL 12 EMDB 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 13 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MEROPS 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 15 PDBsum 15 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 REPRODUCTION-2DPAGE 2 RNAct 1 Reactome 2 RefSeq 3 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TCDB 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7637782

Title: Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33.

PubMed ID: 7637782

DOI: 10.1038/376509a0

PubMed ID: 8973361

Title: A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution.

PubMed ID: 8973361

DOI: 10.1016/s0378-1119(96)00445-3

PubMed ID: 10574455

Title: Characterization of the human dihydropyrimidinase-related protein 2 (DRP-2) gene.

PubMed ID: 10574455

DOI: 10.1093/dnares/6.5.291

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10757975

Title: Neurofibrillary tangle-associated collapsin response mediator protein-2 (CRMP-2) is highly phosphorylated on Thr-509, Ser-518, and Ser-522.

PubMed ID: 10757975

DOI: 10.1021/bi992323h

PubMed ID: 11477421

Title: CRMP-2 induces axons in cultured hippocampal neurons.

PubMed ID: 11477421

DOI: 10.1038/90476

PubMed ID: 15466863

Title: GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins regulates axon elongation in primary neurons.

PubMed ID: 15466863

DOI: 10.1074/jbc.c400412200

PubMed ID: 16260607

Title: CRMP-2 is involved in kinesin-1-dependent transport of the Sra-1/WAVE1 complex and axon formation.

PubMed ID: 16260607

DOI: 10.1128/mcb.25.22.9920-9935.2005

PubMed ID: 14685275

Title: Structural bases for CRMP function in plexin-dependent semaphorin3A signaling.

PubMed ID: 14685275

DOI: 10.1038/sj.emboj.7600021

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19652227

Title: Semaphorin3A signaling mediated by Fyn-dependent tyrosine phosphorylation of collapsin response mediator protein 2 at tyrosine 32.

PubMed ID: 19652227

DOI: 10.1074/jbc.m109.000240

PubMed ID: 19235893

Title: Protein product of CLN6 gene responsible for variant late-onset infantile neuronal ceroid lipofuscinosis interacts with CRMP-2.

PubMed ID: 19235893

DOI: 10.1002/jnr.22032

PubMed ID: 20801876

Title: Collapsin response mediator protein-2 (Crmp2) regulates trafficking by linking endocytic regulatory proteins to dynein motors.

PubMed ID: 20801876

DOI: 10.1074/jbc.c110.166066

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22905912

Title: Resveratrol-induced changes of the human adipocyte secretion profile.

PubMed ID: 22905912

DOI: 10.1021/pr300539b

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 17250651

Title: The structure of human collapsin response mediator protein 2, a regulator of axonal growth.

PubMed ID: 17250651

DOI: 10.1111/j.1471-4159.2006.04401.x

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 572
  • Mass: 62294
  • Checksum: 5CDB6CF7F5C308AD
  • Sequence:
    • MSYQGKKNIP RITSDRLLIK GGKIVNDDQS FYADIYMEDG LIKQIGENLI VPGGVKTIEA 
HSRMVIPGGI DVHTRFQMPD QGMTSADDFF QGTKAALAGG TTMIIDHVVP EPGTSLLAAF 
DQWREWADSK SCCDYSLHVD ISEWHKGIQE EMEALVKDHG VNSFLVYMAF KDRFQLTDCQ 
IYEVLSVIRD IGAIAQVHAE NGDIIAEEQQ RILDLGITGP EGHVLSRPEE VEAEAVNRAI 
TIANQTNCPL YITKVMSKSS AEVIAQARKK GTVVYGEPIT ASLGTDGSHY WSKNWAKAAA 
FVTSPPLSPD PTTPDFLNSL LSCGDLQVTG SAHCTFNTAQ KAVGKDNFTL IPEGTNGTEE 
RMSVIWDKAV VTGKMDENQF VAVTSTNAAK VFNLYPRKGR IAVGSDADLV IWDPDSVKTI 
SAKTHNSSLE YNIFEGMECR GSPLVVISQG KIVLEDGTLH VTEGSGRYIP RKPFPDFVYK 
RIKARSRLAE LRGVPRGLYD GPVCEVSVTP KTVTPASSAK TSPAKQQAPP VRNLHQSGFS 
LSGAQIDDNI PRRTTQRIVA PPGGRANITS LG

Genular Protein ID: 2256628861

Symbol: A0A1C7CYX9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A1C7CYX9

Database IDs:

ARBA 7 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 2 GeneTree 1 HGNC 1 InterPro 5 MANE-Select 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22905912

Title: Resveratrol-induced changes of the human adipocyte secretion profile.

PubMed ID: 22905912

DOI: 10.1021/pr300539b

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 677
  • Mass: 73503
  • Checksum: DBD8267E8334B126
  • Sequence:
    • MAERKQSGKA AEDEEVPAFF KNLGSGSPKP RQKFCGMFCP VEGSSENKTI DFDSLSVGRG 
SGQVVAQQRD VAHLGPDPQP PYSRQGRRAG GEPSVESGRK VEIRRASGKE ALQNINDQSD 
RLLIKGGKIV NDDQSFYADI YMEDGLIKQI GENLIVPGGV KTIEAHSRMV IPGGIDVHTR 
FQMPDQGMTS ADDFFQGTKA ALAGGTTMII DHVVPEPGTS LLAAFDQWRE WADSKSCCDY 
SLHVDISEWH KGIQEEMEAL VKDHGVNSFL VYMAFKDRFQ LTDCQIYEVL SVIRDIGAIA 
QVHAENGDII AEEQQRILDL GITGPEGHVL SRPEEVEAEA VNRAITIANQ TNCPLYITKV 
MSKSSAEVIA QARKKGTVVY GEPITASLGT DGSHYWSKNW AKAAAFVTSP PLSPDPTTPD 
FLNSLLSCGD LQVTGSAHCT FNTAQKAVGK DNFTLIPEGT NGTEERMSVI WDKAVVTGKM 
DENQFVAVTS TNAAKVFNLY PRKGRIAVGS DADLVIWDPD SVKTISAKTH NSSLEYNIFE 
GMECRGSPLV VISQGKIVLE DGTLHVTEGS GRYIPRKPFP DFVYKRIKAR SRLAELRGVP 
RGLYDGPVCE VSVTPKTVTP ASSAKTSPAK QQAPPVRNLH QSGFSLSGAQ IDDNIPRRTT 
QRIVAPPGGR ANITSLG

Genular Protein ID: 2708384111

Symbol: Q59GB4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59GB4

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 2 IntAct 1 InterPro 5 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 1 SUPFAM 2

Sequence Information:

  • Length: 628
  • Mass: 68184
  • Checksum: C8C999B286EE9604
  • Sequence:
    • IDFDSLSVGR GSGQVVAQQR DVAHLGPDPQ PPYSRQGRRA GGEPSVESGR KVEIRRASGK 
EALQNINDQS DRLLIKGGKI VNDDQSFYAD IYMEDGLIKQ IGENLIVPGG VKTIEAHSRM 
VIPGGIDVHT RFQMPDQGMT SADDFFQGTK AALAGGTTMI IDHVVPEPGT SLLAAFDQWR 
EWADSKSCCD YSLHVDISEW HKGIQEEMEA LVKDHGVNSF LVYMAFKDRF QLTDCQIYEV 
LSVIRDIGAI AQVHAENGDI IAEEQQRILD LGITGPEGHV LSRPEEVEAE AVNRAITIAN 
QTNCPLYITK VMSKSSAEVI AQARKKGTVV YGEPITASLG TDGSHYWSKN WAKAAAFVTS 
PPLSPDPTTP DFLNSLLSCG DLQVTGSAHC TFNTAQKAVG KDNFTLIPEG TNGTEERMSV 
IWDKAVVTGK MDENQFVAVT STNAAKVFNL YPRKGRIAVG SDADLVIWDP DSVKTISAKT 
HNSSLEYNIF EGMECRGSPL VVISQGKIVL EDGTLHVTEG SGRYIPRKPF PDFVYKRIKA 
RSRLAELRGV PRGLYDGPVC EVSVTPKTVT PASSAKTSPA KQQAPPVRNL HQSGFSLSGA 
QIDDNIPRRT TQRIVAPPGG RANITSLG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.