Details for: ECE1

Gene ID: 1889

Symbol: ECE1

Ensembl ID: ENSG00000117298

Description: endothelin converting enzyme 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 257.2403
    Cell Significance Index: -40.0100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 165.2714
    Cell Significance Index: -41.9200
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 87.6891
    Cell Significance Index: -41.4000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 85.7093
    Cell Significance Index: -34.8200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 77.7044
    Cell Significance Index: -39.9700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 36.4915
    Cell Significance Index: -34.8400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 33.6590
    Cell Significance Index: -41.5000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 15.0474
    Cell Significance Index: -40.3100
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 11.0827
    Cell Significance Index: -34.0400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.6334
    Cell Significance Index: -41.9600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 6.5836
    Cell Significance Index: 176.4100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 5.3378
    Cell Significance Index: 278.0400
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 2.1498
    Cell Significance Index: 13.2300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.6403
    Cell Significance Index: 113.4400
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 1.6309
    Cell Significance Index: 11.0500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.5725
    Cell Significance Index: 155.5600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.4850
    Cell Significance Index: 294.7000
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 1.4050
    Cell Significance Index: 8.3000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.1691
    Cell Significance Index: 234.5300
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.1291
    Cell Significance Index: 16.2400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.1021
    Cell Significance Index: 21.5100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7620
    Cell Significance Index: 82.8900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.6950
    Cell Significance Index: 249.2900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.6869
    Cell Significance Index: 375.1100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.5972
    Cell Significance Index: 44.5100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.5935
    Cell Significance Index: 81.5100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.4823
    Cell Significance Index: 82.3500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.4483
    Cell Significance Index: 19.8300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4474
    Cell Significance Index: 20.2800
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.4053
    Cell Significance Index: 5.8200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3645
    Cell Significance Index: 252.1300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3540
    Cell Significance Index: 7.6700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.3255
    Cell Significance Index: 15.3000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.3249
    Cell Significance Index: 12.3100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.3031
    Cell Significance Index: 15.3200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.2968
    Cell Significance Index: 185.3400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2915
    Cell Significance Index: 128.8800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2884
    Cell Significance Index: 260.3800
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.2716
    Cell Significance Index: 4.0700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2672
    Cell Significance Index: 32.8600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.2581
    Cell Significance Index: 163.9300
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.2572
    Cell Significance Index: 4.5500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2548
    Cell Significance Index: 7.3400
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.2532
    Cell Significance Index: 1.5300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.2289
    Cell Significance Index: 12.8500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2260
    Cell Significance Index: 5.6500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.2098
    Cell Significance Index: 16.1000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2005
    Cell Significance Index: 36.1500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0807
    Cell Significance Index: 10.3500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.0625
    Cell Significance Index: 0.7100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.0542
    Cell Significance Index: 1.5600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0472
    Cell Significance Index: 1.6600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0366
    Cell Significance Index: 4.3200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0287
    Cell Significance Index: 53.0100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0238
    Cell Significance Index: 3.0800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0214
    Cell Significance Index: 32.9600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0015
    Cell Significance Index: 0.2900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0013
    Cell Significance Index: 2.5000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0051
    Cell Significance Index: -0.1300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0148
    Cell Significance Index: -10.9400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0149
    Cell Significance Index: -20.3100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0300
    Cell Significance Index: -22.0300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0417
    Cell Significance Index: -18.9300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0500
    Cell Significance Index: -28.1900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0503
    Cell Significance Index: -38.0700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0534
    Cell Significance Index: -2.4900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0608
    Cell Significance Index: -4.0900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0949
    Cell Significance Index: -13.8000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1137
    Cell Significance Index: -23.9500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1170
    Cell Significance Index: -7.1900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1252
    Cell Significance Index: -36.0100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1832
    Cell Significance Index: -18.7100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2127
    Cell Significance Index: -4.5300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2285
    Cell Significance Index: -16.1600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2298
    Cell Significance Index: -26.3300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2335
    Cell Significance Index: -27.2100
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: -0.2974
    Cell Significance Index: -2.6400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3111
    Cell Significance Index: -16.1600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3130
    Cell Significance Index: -35.7300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.3423
    Cell Significance Index: -9.1400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.3442
    Cell Significance Index: -9.6200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3628
    Cell Significance Index: -37.7800
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: -0.3767
    Cell Significance Index: -1.6400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3794
    Cell Significance Index: -23.2600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4026
    Cell Significance Index: -21.1400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.4339
    Cell Significance Index: -27.9900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4399
    Cell Significance Index: -14.0900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4668
    Cell Significance Index: -36.9700
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: -0.5503
    Cell Significance Index: -3.4000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.5620
    Cell Significance Index: -9.4100
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.6442
    Cell Significance Index: -10.2200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.6584
    Cell Significance Index: -17.9200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.6732
    Cell Significance Index: -42.4300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.6889
    Cell Significance Index: -11.6100
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.7229
    Cell Significance Index: -10.6700
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.7298
    Cell Significance Index: -10.2100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.7607
    Cell Significance Index: -14.0600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.7738
    Cell Significance Index: -22.7300
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: -0.7797
    Cell Significance Index: -5.6000
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.8123
    Cell Significance Index: -8.4800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Expression Pattern**: ECE1 is predominantly expressed in endothelial cells, but also found in cortical cells of the adrenal gland, lung endothelial cells, vascular leptomeningeal cells, and other cell types. 2. **Function**: ECE1 converts big endothelin-1 to endothelin-1, the biologically active form of endothelin, which plays a crucial role in regulating vascular tone and blood pressure. 3. **Metalloendopeptidase Activity**: ECE1 exhibits metalloendopeptidase activity, allowing it to cleave and activate peptides, including endothelins. 4. **Signaling Pathways**: ECE1 is involved in multiple signaling pathways, including those regulating vascular development, axon guidance, hormone regulation, and blood pressure. **Pathways and Functions** ECE1's involvement in various signaling pathways highlights its multifaceted role in maintaining physiological balance: 1. **Regulation of Vascular Tone**: ECE1 converts big endothelin-1 to endothelin-1, the biologically active form of endothelin, which regulates vascular tone and blood pressure. 2. **Axon Guidance**: ECE1 is involved in semaphorin-plexin signaling pathway, which regulates axon guidance and neuronal development. 3. **Hormone Regulation**: ECE1 processes peptide hormones, such as substance P, which plays a role in regulating various physiological processes. 4. **Developmental Processes**: ECE1 is involved in embryonic heart tube development, ear development, and pharyngeal system development, highlighting its importance in embryonic development. 5. **Blood Pressure Regulation**: ECE1's expression in endothelial cells and its role in regulating endothelin-1 levels make it a key player in maintaining systemic arterial blood pressure. **Clinical Significance** Dysregulation of ECE1 has been implicated in various diseases, including: 1. **Hypertension**: ECE1's role in regulating endothelin-1 levels makes it a potential target for the treatment of hypertension. 2. **Cardiovascular Diseases**: ECE1's involvement in vascular development and maintenance highlights its potential role in cardiovascular diseases, such as atherosclerosis and heart failure. 3. **Neurological Disorders**: ECE1's role in axon guidance and neuronal development suggests its potential involvement in neurological disorders, such as stroke and neurodegenerative diseases. 4. **Cancer**: ECE1's expression in various cell types and its role in processing peptide hormones make it a potential target for cancer therapy. In conclusion, ECE1 is a critical gene involved in multiple physiological and pathological processes. Its role in regulating endothelin-1 levels, processing peptide hormones, and participating in signaling pathways underscores its importance in maintaining vascular homeostasis and overall physiological balance. Further research is necessary to fully elucidate the functions and clinical significance of ECE1.

Genular Protein ID: 3239516794

Symbol: ECE1_HUMAN

Name: Endothelin-converting enzyme 1

UniProtKB Accession Codes:

P42892 A8K3P1 B4E291 Q14217 Q17RN5 Q2Z2K8 Q58GE7 Q5THM5 Q5THM7 Q5THM8 Q9UJQ6 Q9UPF4 Q9UPM4 Q9Y501

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 1 CTD 1 ChEBI 4 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 DrugCentral 1 EC 1 EMBL 51 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 35 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MEROPS 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 2 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 1 RefSeq 7 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7695628

Title: Cloning and sequencing of a human endothelin converting enzyme in renal adenocarcinoma (ACHN) cells producing endothelin-2.

PubMed ID: 7695628

DOI: 10.1006/bbrc.1995.1397

PubMed ID: 7864876

Title: Cloning and functional expression of human endothelin-converting enzyme cDNA.

PubMed ID: 7864876

DOI: 10.1006/bbrc.1995.1258

PubMed ID: 8530372

Title: Organization of the gene encoding the human endothelin-converting enzyme (ECE-1).

PubMed ID: 8530372

DOI: 10.1074/jbc.270.50.29794

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10491078

Title: A fourth isoform of endothelin-converting enzyme (ECE-1) is generated from an additional promoter.

PubMed ID: 10491078

DOI: 10.1046/j.1432-1327.1999.00602.x

PubMed ID: 9396733

Title: Human endothelin-converting enzyme (ECE-1): three isoforms with distinct subcellular localizations.

PubMed ID: 9396733

DOI: 10.1042/bj3280871

PubMed ID: 7805846

Title: Molecular characterization of human and bovine endothelin converting enzyme (ECE-1).

PubMed ID: 7805846

DOI: 10.1016/0014-5793(94)01277-6

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16263699

Title: Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach.

PubMed ID: 16263699

DOI: 10.1074/mcp.m500324-mcp200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 26931059

Title: N-terminal domain of Bothrops asper Myotoxin II enhances the activity of endothelin converting enzyme-1 and neprilysin.

PubMed ID: 26931059

DOI: 10.1038/srep22413

PubMed ID: 27102936

Title: Corrigendum: N-terminal domain of Bothrops asper Myotoxin II enhances the activity of endothelin converting enzyme-1 and neprilysin.

PubMed ID: 27102936

DOI: 10.1038/srep24333

PubMed ID: 37835445

Title: The Tetraspanin Tspan8 Associates with Endothelin Converting Enzyme ECE1 and Regulates Its Activity.

PubMed ID: 37835445

DOI: 10.3390/cancers15194751

PubMed ID: 18992253

Title: Structure of human endothelin-converting enzyme I complexed with phosphoramidon.

PubMed ID: 18992253

DOI: 10.1016/j.jmb.2008.10.052

PubMed ID: 9915973

Title: A loss-of-function mutation in the endothelin-converting enzyme 1 (ECE-1) associated with Hirschsprung disease, cardiac defects, and autonomic dysfunction.

PubMed ID: 9915973

DOI: 10.1086/302184

Sequence Information:

  • Length: 770
  • Mass: 87164
  • Checksum: DD88A59748B22F80
  • Sequence:
    • MRGVWPPPVS ALLSALGMST YKRATLDEED LVDSLSEGDA YPNGLQVNFH SPRSGQRCWA 
ARTQVEKRLV VLVVLLAAGL VACLAALGIQ YQTRSPSVCL SEACVSVTSS ILSSMDPTVD 
PCHDFFSYAC GGWIKANPVP DGHSRWGTFS NLWEHNQAII KHLLENSTAS VSEAERKAQV 
YYRACMNETR IEELRAKPLM ELIERLGGWN ITGPWAKDNF QDTLQVVTAH YRTSPFFSVY 
VSADSKNSNS NVIQVDQSGL GLPSRDYYLN KTENEKVLTG YLNYMVQLGK LLGGGDEEAI 
RPQMQQILDF ETALANITIP QEKRRDEELI YHKVTAAELQ TLAPAINWLP FLNTIFYPVE 
INESEPIVVY DKEYLEQIST LINTTDRCLL NNYMIWNLVR KTSSFLDQRF QDADEKFMEV 
MYGTKKTCLP RWKFCVSDTE NNLGFALGPM FVKATFAEDS KSIATEIILE IKKAFEESLS 
TLKWMDEETR KSAKEKADAI YNMIGYPNFI MDPKELDKVF NDYTAVPDLY FENAMRFFNF 
SWRVTADQLR KAPNRDQWSM TPPMVNAYYS PTKNEIVFPA GILQAPFYTR SSPKALNFGG 
IGVVVGHELT HAFDDQGREY DKDGNLRPWW KNSSVEAFKR QTECMVEQYS NYSVNGEPVN 
GRHTLGENIA DNGGLKAAYR AYQNWVKKNG AEHSLPTLGL TNNQLFFLGF AQVWCSVRTP 
ESSHEGLITD PHSPSRFRVI GSLSNSKEFS EHFRCPPGSP MNPPHKCEVW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.