Details for: EPB41L2

Gene ID: 2037

Symbol: EPB41L2

Ensembl ID: ENSG00000079819

Description: erythrocyte membrane protein band 4.1 like 2

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 5.8
    Marker Score: 4365
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 5.47
    Marker Score: 6816
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 5.34
    Marker Score: 1929
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 3.99
    Marker Score: 5365
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 3.72
    Marker Score: 4503
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 3.41
    Marker Score: 1697
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 3.35
    Marker Score: 9561
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 3.31
    Marker Score: 7921.5
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 3.14
    Marker Score: 6034
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 3.06
    Marker Score: 893
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 2.9
    Marker Score: 5274
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 2.8
    Marker Score: 1559
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.79
    Marker Score: 1623
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.69
    Marker Score: 1571
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 2.67
    Marker Score: 797
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.65
    Marker Score: 52713
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.58
    Marker Score: 2974
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.41
    Marker Score: 2299
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.41
    Marker Score: 51373
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.36
    Marker Score: 5182
  • Cell Name: fat cell (CL0000136)
    Fold Change: 2.35
    Marker Score: 1312
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 2.28
    Marker Score: 724
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 2.19
    Marker Score: 3030.5
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 2.16
    Marker Score: 6159
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.02
    Marker Score: 18978
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.96
    Marker Score: 120594
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.94
    Marker Score: 3259
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.91
    Marker Score: 18139
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.83
    Marker Score: 32475
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 1.79
    Marker Score: 4695
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.79
    Marker Score: 66000
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 1.79
    Marker Score: 1789
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 1.73
    Marker Score: 489
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 1.72
    Marker Score: 22654
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.71
    Marker Score: 7108
  • Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
    Fold Change: 1.71
    Marker Score: 2471
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.68
    Marker Score: 386
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.67
    Marker Score: 1446
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 1.66
    Marker Score: 2554
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 1.63
    Marker Score: 881
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.58
    Marker Score: 2442
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.55
    Marker Score: 11870
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 1.54
    Marker Score: 2121
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 1.54
    Marker Score: 2235
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.52
    Marker Score: 57866
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 1.52
    Marker Score: 1001
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 1.52
    Marker Score: 1635
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.5
    Marker Score: 5567
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 1.49
    Marker Score: 545
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.48
    Marker Score: 6194.5
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 1.48
    Marker Score: 990
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.48
    Marker Score: 1584
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.48
    Marker Score: 50216
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 1.47
    Marker Score: 1848
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.46
    Marker Score: 870
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.45
    Marker Score: 608
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.44
    Marker Score: 2937.5
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 1.42
    Marker Score: 885
  • Cell Name: pericyte (CL0000669)
    Fold Change: 1.4
    Marker Score: 820
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 1.37
    Marker Score: 901
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.36
    Marker Score: 8852
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 1.32
    Marker Score: 748
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.32
    Marker Score: 14864
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 1.32
    Marker Score: 1628
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.32
    Marker Score: 496
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 1.31
    Marker Score: 346
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 1.29
    Marker Score: 641
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 1.26
    Marker Score: 400
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.26
    Marker Score: 611
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 1.26
    Marker Score: 1343
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 1.25
    Marker Score: 1796
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.25
    Marker Score: 10716
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 1.25
    Marker Score: 651
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 1.23
    Marker Score: 1184
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 1.22
    Marker Score: 1043
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.21
    Marker Score: 2856
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.2
    Marker Score: 386
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.18
    Marker Score: 1462
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 1.16
    Marker Score: 286
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 1.14
    Marker Score: 2899
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.14
    Marker Score: 17024
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.14
    Marker Score: 311
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 1.13
    Marker Score: 393
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 1.12
    Marker Score: 1057
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.11
    Marker Score: 4529
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 1.09
    Marker Score: 776
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 1.09
    Marker Score: 1161
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.08
    Marker Score: 281
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 1.08
    Marker Score: 2540.5
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 1.04
    Marker Score: 377
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.04
    Marker Score: 388
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 1.03
    Marker Score: 1109
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 1.02
    Marker Score: 357
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.02
    Marker Score: 1152
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 1.01
    Marker Score: 948
  • Cell Name: peritubular capillary endothelial cell (CL1001033)
    Fold Change: 1
    Marker Score: 233
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71697
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47922
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.98
    Marker Score: 903
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.98
    Marker Score: 5904

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Other Information

**Key characteristics:** - It is a glycoprotein with a molecular weight of approximately 120 kDa. - It is expressed in various cell types in the CNS, including photoreceptor cells, cardiac neurons, and microglia. - It is a transmembrane protein that is primarily localized to the plasma membrane of neurons and astrocytes. - It is a key component of the blood-brain barrier (BBB), which is a network of blood-brain-barrier-forming cells that protects the brain from harmful substances in the blood. **Pathways and functions:** - EPB41L2 is involved in the organization and stability of the blood-brain barrier. - It helps to maintain the integrity of the BBB by interacting with other proteins, such as EPH4A and occludin. - It also regulates the trafficking of proteins between the blood and the CNS. - It is involved in the regulation of neuronal migration and neurite outgrowth. - It is also involved in the development and maintenance of the BBB. **Clinical significance:** - Mutations in EPB41L2 have been linked to several neurological disorders, including autism, schizophrenia, and epilepsy. - Targeting EPB41L2 has been investigated as a potential therapeutic strategy for these disorders. - EPB41L2 is a promising target for the treatment of neurological diseases that are characterized by BBB dysfunction.

Genular Protein ID: 1209773227

Symbol: E41L2_HUMAN

Name: Band 4.1-like protein 2

UniProtKB Accession Codes:

O43491 B4DHI8 E9PPD9 Q5T4F0 Q68DV2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 3 CTD 1 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 EMBL 10 EPD 1 Ensembl 7 ExpressionAtlas 1 GO 18 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 14 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRINTS 2 PRO 1 PROSITE 3 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 6 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 1 RefSeq 11 SAM 1 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9598318

Title: Cloning and characterization of 4.1G (EPB41L2), a new member of the skeletal protein 4.1 (EPB41) gene family.

PubMed ID: 9598318

DOI: 10.1006/geno.1998.5265

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 16254212

Title: Activation of the endothelial store-operated ISOC Ca2+ channel requires interaction of protein 4.1 with TRPC4.

PubMed ID: 16254212

DOI: 10.1161/01.res.0000193597.65217.00

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18023480

Title: Protein 4.1G binds to a unique motif within the FcgammaRI cytoplasmic tail.

PubMed ID: 18023480

DOI: 10.1016/j.molimm.2007.10.024

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22361696

Title: Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy.

PubMed ID: 22361696

DOI: 10.1016/j.jprot.2012.01.030

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 23870127

Title: Cortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphase.

PubMed ID: 23870127

DOI: 10.1016/j.cell.2013.06.010

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 1005
  • Mass: 112588
  • Checksum: E86CB17488F6045F
  • Sequence:
    • MTTEVGSVSE VKKDSSQLGT DATKEKPKEV AENQQNQSSD PEEEKGSQPP PAAESQSSLR 
RQKREKETSE SRGISRFIPP WLKKQKSYTL VVAKDGGDKK EPTQAVVEEQ VLDKEEPLPE 
EQRQAKGDAE EMAQKKQEIK VEVKEEKPSV SKEEKPSVSK VEMQPTELVS KEREEKVKET 
QEDKLEGGAA KRETKEVQTN ELKAEKASQK VTKKTKTVQC KVTLLDGTEY SCDLEKHAKG 
QVLFDKVCEH LNLLEKDYFG LLFQESPEQK NWLDPAKEIK RQLRNLPWLF TFNVKFYPPD 
PSQLTEDITR YFLCLQLRQD IASGRLPCSF VTHALLGSYT LQAELGDYDP EEHGSIDLSE 
FQFAPTQTKE LEEKVAELHK THRGLSPAQA DSQFLENAKR LSMYGVDLHH AKDSEGVDIK 
LGVCANGLLI YKDRLRINRF AWPKILKISY KRSNFYIKVR PAELEQFEST IGFKLPNHRA 
AKRLWKVCVE HHTFYRLVSP EQPPKAKFLT LGSKFRYSGR TQAQTRQAST LIDRPAPHFE 
RTSSKRVSRS LDGAPIGVMD QSLMKDFPGA AGEISAYGPG LVSIAVVQDG DGRREVRSPT 
KAPHLQLIEG KKNSLRVEGD NIYVRHSNLM LEELDKAQED ILKHQASISE LKRNFMESTP 
EPRPNEWEKR RITPLSLQTQ GSSHETLNIV EEKKRAEVGK DERVITEEMN GKEISPGSGP 
GEIRKVEPVT QKDSTSLSSE SSSSSSESEE EDVGEYRPHH RVTEGTIREE QEYEEEVEEE 
PRPAAKVVER EEAVPEASPV TQAGASVITV ETVIQENVGA QKIPGEKSVH EGALKQDMGE 
EAEEEPQKVN GEVSHVDIDV LPQIICCSEP PVVKTEMVTI SDASQRTEIS TKEVPIVQTE 
TKTITYESPQ IDGGAGGDSG TLLTAQTITS ESVSTTTTTH ITKTVKGGIS ETRIEKRIVI 
TGDGDIDHDQ ALAQAIREAR EQHPDMSVTR VVVHKETELA EEGED

Genular Protein ID: 2501236292

Symbol: Q59FD8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59FD8

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 13 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRINTS 2 PROSITE 4 PeptideAtlas 1 Pfam 5 PharmGKB 1 RefSeq 1 SAM 1 SMART 3 SUPFAM 3

Sequence Information:

  • Length: 676
  • Mass: 76294
  • Checksum: ED787FDB87791B83
  • Sequence:
    • AVAMTTEVGS VSEVKKDSSQ LGTDATKEKP KEVAENQQNQ SSDPEEEKGS QPPPAAESQS 
SLRRQKREKE TSESRGISRF IPPWLKKQKS YTLVVAKDGG DKKEPTQAVV EEQVLDKEEP 
LPEEQRQAKG DAEEMAQKKQ EIKVEVKEEK PSVSKEEKPS VSKVEMQPTE LVSKEREEKV 
KETQEDKLEG GAAKRETKEV QTNELKAEKA SQKVTKKTKT VQCKVTLLDG TEYSCDLEKH 
AKGQVLFDKV CEHLNLLEKD YFGLLFQESP EQKNWLDPAK EIKRQLRNLP WLFTFNVKFY 
PPDPSQLTED ITRYFLCLQL RQDIASGRLP CSFVTHALLG SYTLQAELGD YDPEEHGSID 
LSEFQFAPTQ TKELEEKVAE LHKTHRGLSP AQADSQFLEN AKRLSMYGVD LHHAKDSEGV 
DIKLGVCANG LLIYKDRLRI NRFAWPKILK ISYKRSNFYI KVRPAELEQF ESTIGFKLPN 
HRAAKRLWKV CVEHHTFYRL VSPEQPPKAK FLTLGSKFRY SGRTQAQTRQ ASTLIDRPAP 
HFERTSSKRV SRSLDGAPIG VMDQSLMKDF PGAAGEISAY GPGLVSIAVV QDGDGRREVR 
SPTKAPHLQL IEGKTVKGGI SETRIEKRIV ITGDGDIDHD QALAQAIREA REQHPDMSVT 
RVVVHKETEL AEEGED

Genular Protein ID: 2642233263

Symbol: B4DJ76_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DJ76

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 3 Genevisible 1 GenomeRNAi 1 InterPro 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 1

Sequence Information:

  • Length: 294
  • Mass: 31946
  • Checksum: 7B4281F66827CEFC
  • Sequence:
    • MDQSLMKDFP GAAGEISAYG PGLVSIAVVQ DGDGRREVRS PTKAPHLQLI EGKSSHETLN 
IVEEKKRAEV GKDERVITEE MNGKEISPGS GPGEIRKVEP VTQKDSTSLS SESSSSSSES 
EEEDVGEYRP HHRVTEGTIR EEQEYEEEVE EEPRPAAKPP VVKTEMVTIS DASQRTEIST 
KEVPIVQTET KTITYESPQI DGGAGGDSGT LLTAQTITSE SVSTTTTTHI TKTVKGGISE 
TRIEKRIVIT GDGDIDHDQA LAQAIREARE QHPDMSVTRV VVHKETELAE EGED

Genular Protein ID: 1859775122

Symbol: I6L9B1_HUMAN

Name: N/A

UniProtKB Accession Codes:

I6L9B1

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 EPD 1 GO 2 Gene3D 2 GenomeRNAi 1 InterPro 12 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRINTS 2 PROSITE 4 PeptideAtlas 1 Pfam 4 RefSeq 5 SAM 1 SMART 3 SUPFAM 3 UCSC 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.M111.015131

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.O114.044792

Sequence Information:

  • Length: 633
  • Mass: 71643
  • Checksum: 9E0DDA950B5B0E95
  • Sequence:
    • MTTEVGSVSE VKKDSSQLGT DATKEKPKEV AENQQNQSSD PEEEKGSQPP PAAESQSSLR 
RQKREKETSE SRGISRFIPP WLKKQKSYTL VVAKDGGDKK EPTQAVVEEQ VLDKEEPLPE 
EQRQAKGDAE EMAQKKQEIK VEVKEEKPSV SKEEKPSVSK VEMQPTELVS KEREEKVKET 
QEDKLEGGAA KRETKEVQTN ELKAEKASQK VTKKTKTVQC KVTLLDGTEY SCDLEKHAKG 
QVLFDKVCEH LNLLEKDYFG LLFQESPEQK NWLDPAKEIK RQLRNLPWLF TFNVKFYPPD 
PSQLTEDITR YFLCLQLRQD IASGRLPCSF VTHALLGSYT LQAELGDYDP EEHGSIDLSE 
FQFAPTQTKE LEEKVAELHK THRGLSPAQA DSQFLENAKR LSMYGVDLHH AKDSEGVDIK 
LGVCANGLLI YKDRLRINRF AWPKILKISY KRSNFYIKVR PAELEQFEST IGFKLPNHRA 
AKRLWKVCVE HHTFYRLVSP EQPPKAKFLT LGSKFRYSGR TQAQTRQAST LIDRPAPHFE 
RTSSKRVSRS LDGAPIGVMD QSLMKDFPGA AGEISAYGPG LVSIAVVQDG DGRREVRSPT 
KAPHLQLIEG KSSHETLNIV EEKSGQRLGK TKE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.