Details for: ERH
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 86.42rCSI 78.05%PRS 6.36
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CSI 79.61rCSI 65.99%PRS 6.84
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CSI 79.04rCSI 69.5%PRS 5.21
-
CSI 75.67rCSI 59.53%PRS 8.6
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CSI 73.09rCSI 72.95%PRS 6.17
-
CSI 72.01rCSI 58.22%PRS 7.09
-
CSI 71.34rCSI 47.42%PRS 8.59
-
CSI 69.13rCSI 72.26%PRS 7.57
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CSI 67.76rCSI 53.56%PRS 4.96
-
CSI 66.6rCSI 57.66%PRS 8.01
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CSI 66.22rCSI 76.48%PRS 6.42
-
CSI 66.2rCSI 58.14%PRS 8.08
-
CSI 64.3rCSI 61.9%PRS 7.45
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CSI 64.28rCSI 61.98%PRS 4.46
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CSI 61.24rCSI 70.1%PRS 14.95
-
CSI 59.22rCSI 71.09%PRS 7.12
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CSI 58.33rCSI 73.2%PRS 9.17
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CSI 57.05rCSI 77.73%PRS 6.44
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CSI 55.63rCSI 46.07%PRS 7.22
-
CSI 55.49rCSI 77.09%PRS 7.46
-
CSI 50.39rCSI 42.24%PRS 8.61
-
CSI 50.13rCSI 71.55%PRS 8.13
-
CSI 49.18rCSI 51.52%PRS 6.69
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CSI 45.96rCSI 53.98%PRS 8.61
-
CSI 44.11rCSI 43.38%PRS 7.81
-
CSI 41.29rCSI 66.45%PRS 5.52
-
CSI 40.91rCSI 59%PRS 10.05
-
CSI 37.88rCSI 39.68%PRS 7.65
-
CSI 36.47rCSI 32.38%PRS 7.19
-
CSI 36.21rCSI 41.87%PRS 5.27
-
CSI 35.08rCSI 43.4%PRS 6.31
-
CSI 35.08rCSI 47.96%PRS 12.28
-
CSI 34.72rCSI 50.05%PRS 11.63
-
CSI 33.92rCSI 54.11%PRS 6.2
-
CSI 33.91rCSI 58.1%PRS 9.66
-
CSI 30.28rCSI 27.94%PRS 7.32
-
CSI 30.1rCSI 41.13%PRS 7.97
-
CSI 29.47rCSI 30.03%PRS 10.35
-
CSI 28.98rCSI 43.08%PRS 9.06
-
CSI 28.73rCSI 44.4%PRS 6.76
-
CSI 28.61rCSI 19.98%PRS 7.58
-
CSI 27.57rCSI 40.43%PRS 9.49
-
CSI 27.53rCSI 42.11%PRS 11.75
-
CSI 26.23rCSI 74.88%PRS 12.8
-
CSI 25.94rCSI 75.11%PRS 8.16
-
CSI 25.46rCSI 19.74%PRS 6.83
-
CSI 24.29rCSI 37.33%PRS 10.33
-
CSI 23.9rCSI 30.67%PRS 7.05
-
CSI 22.58rCSI 48.07%PRS 11.66
-
CSI 22.58rCSI 57.34%PRS 7.33
-
CSI 22.45rCSI 40.8%PRS 10.98
-
CSI 21.79rCSI 41.2%PRS 15.99
-
CSI 21.08rCSI 40.23%PRS 17.36
-
CSI 20.32rCSI 25.87%PRS 8.35
-
CSI 20.28rCSI 65.09%PRS 10.74
-
CSI 20.06rCSI 27.78%PRS 10.37
-
CSI 19.9rCSI 69.83%PRS 13.09
-
CSI 19.31rCSI 16.91%PRS 9.7
-
CSI 19.25rCSI 40.94%PRS 13.39
-
CSI 18.9rCSI 13.14%PRS 8.43
-
CSI 18.8rCSI 17.26%PRS 8.18
-
CSI 18.18rCSI 41.43%PRS 7.53
-
CSI 17.9rCSI 36.75%PRS 17.26
-
CSI 17.59rCSI 18.35%PRS 7.39
-
CSI 17.32rCSI 22.21%PRS 8.31
-
CSI 16.45rCSI 32.79%PRS 12.25
-
CSI 16.39rCSI 31.88%PRS 7.33
-
CSI 15.53rCSI 33.91%PRS 14.66
-
CSI 15.49rCSI 45.73%PRS 9.03
-
CSI 15.17rCSI 78.32%PRS 14.47
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CSI 15.08rCSI 15.75%PRS 22.74
-
CSI 14.88rCSI 50.32%PRS 12.32
-
CSI 14.88rCSI 32.94%PRS 6.67
-
CSI 14.07rCSI 38.67%PRS 11.93
-
CSI 14.07rCSI 75.9%PRS 13.82
-
CSI 14.05rCSI 20.16%PRS 5.79
-
CSI 14.04rCSI 20.56%PRS 8.43
-
CSI 13.97rCSI 55.62%PRS 12.73
-
CSI 13.77rCSI 33.14%PRS 11.4
-
CSI 13.57rCSI 59.57%PRS 13.55
-
CSI 13.21rCSI 31.41%PRS 10.83
-
CSI 13.01rCSI 9.63%PRS 6.58
-
CSI 12.79rCSI 10.76%PRS 11.97
-
CSI 12.6rCSI 22.47%PRS 12.33
-
CSI 12.6rCSI 23.09%PRS 39.72
-
CSI 12.54rCSI 72.93%PRS 10.87
-
CSI 12.52rCSI 20.28%PRS 7.34
-
CSI 12.51rCSI 55.03%PRS 7.2
-
CSI 12.4rCSI 16.49%PRS 7.82
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CSI 12.35rCSI 16.5%PRS 13.79
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CSI 12.24rCSI 19.73%PRS 11.6
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CSI 12.21rCSI 8.76%PRS 9.79
-
CSI 12.2rCSI 27.84%PRS 6.55
-
CSI 11.56rCSI 13.01%PRS 11.83
-
CSI 11.51rCSI 9.35%PRS 7.67
-
CSI 11.5rCSI 30.53%PRS 12.27
-
CSI 11.47rCSI 18.12%PRS 7.19
-
CSI 11.42rCSI 56.3%PRS 9.75
-
CSI 11.34rCSI 43.83%PRS 15.39
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CSI 11.25rCSI 10.63%PRS 7.52
-
CSI -16.0rCSI -19.1%PRS 12.6%
-
CSI -15.8rCSI -64.5%PRS 8.0%
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CSI -12.1rCSI -20.4%PRS 4.2%
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CSI -11.1rCSI -22.6%PRS 2.7%
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CSI -10.6rCSI -20.3%PRS 11.6%
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CSI -9.5rCSI -8.6%PRS 11.3%
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CSI -6.0rCSI -37.6%PRS 5.8%
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CSI -5.4rCSI -12.0%PRS 4.4%
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CSI -4.9rCSI -11.2%PRS 7.0%
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CSI -3.9rCSI -39.8%PRS 54.6%
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CSI -3.6rCSI -11.1%PRS 4.9%
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CSI -3.5rCSI -11.0%PRS 4.5%
-
CSI -3.2rCSI -3.2%PRS 11.5%
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CSI -3.0rCSI -17.9%PRS 4.4%
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CSI -2.7rCSI -7.8%PRS 9.3%
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CSI -2.7rCSI -7.7%PRS 10.4%
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CSI -2.5rCSI -9.5%PRS 4.3%
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CSI -2.2rCSI -8.1%PRS 32.7%
-
CSI -2.1rCSI -3.7%PRS 8.8%
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CSI -1.9rCSI -4.5%PRS 9.5%
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CSI -1.9rCSI -32.0%PRS 33.8%
-
CSI -1.7rCSI -6.0%PRS 3.9%
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CSI -1.5rCSI -8.8%PRS 32.2%
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CSI -1.4rCSI -6.5%PRS 24.3%
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CSI -1.4rCSI -2.5%PRS 21.0%
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CSI -1.1rCSI -2.8%PRS 4.1%
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CSI -0.9rCSI -5.5%PRS 33.7%
-
CSI -0.7rCSI -3.4%PRS 15.4%
-
CSI -0.3rCSI -5.0%PRS 52.5%
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CSI -0.2rCSI -0.7%PRS 13.1%
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CSI 0.0rCSI 0.0%PRS 7.7%
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CSI 0.1rCSI 0.2%PRS 4.2%
-
CSI 0.2rCSI 0.9%PRS 10.6%
-
CSI 0.3rCSI 5.9%PRS 49.2%
-
CSI 0.3rCSI 1.4%PRS 30.9%
-
CSI 0.3rCSI 0.9%PRS 11.6%
-
CSI 0.3rCSI 0.9%PRS 6.8%
-
CSI 0.4rCSI 1.1%PRS 12.3%
-
CSI 0.4rCSI 0.5%PRS 4.2%
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CSI 0.4rCSI 0.9%PRS 15.6%
-
CSI 0.6rCSI 3.8%PRS 48.1%
-
CSI 0.6rCSI 3.8%PRS 23.8%
-
CSI 0.6rCSI 5.5%PRS 54.8%
-
CSI 0.6rCSI 15.8%PRS 56.6%
-
CSI 0.7rCSI 1.8%PRS 32.3%
-
CSI 0.7rCSI 4.4%PRS 24.6%
-
CSI 0.7rCSI 4.0%PRS 25.0%
-
CSI 0.8rCSI 2.8%PRS 21.6%
-
CSI 0.9rCSI 11.2%PRS 34.6%
-
CSI 0.9rCSI 1.5%PRS 4.6%
-
CSI 0.9rCSI 1.7%PRS 5.4%
-
CSI 0.9rCSI 2.4%PRS 21.6%
-
CSI 0.9rCSI 7.5%PRS 7.6%
-
CSI 0.9rCSI 19.7%PRS 42.4%
-
CSI 1.0rCSI 3.0%PRS 13.1%
-
CSI 1.0rCSI 1.4%PRS 10.4%
-
CSI 1.0rCSI 2.4%PRS 12.0%
-
CSI 1.1rCSI 1.1%PRS 13.7%
-
CSI 1.1rCSI 4.9%PRS 24.8%
-
CSI 1.2rCSI 3.1%PRS 6.7%
-
CSI 1.3rCSI 2.3%PRS 9.5%
-
CSI 1.4rCSI 14.7%PRS 32.5%
-
CSI 1.4rCSI 2.0%PRS 7.6%
-
CSI 1.4rCSI 21.8%PRS 18.2%
-
CSI 1.5rCSI 16.7%PRS 22.2%
-
CSI 1.5rCSI 35.0%PRS 11.8%
-
CSI 1.5rCSI 3.3%PRS 11.1%
-
CSI 1.6rCSI 2.0%PRS 4.5%
-
CSI 1.6rCSI 2.3%PRS 7.0%
-
CSI 1.6rCSI 25.3%PRS 43.0%
-
CSI 1.6rCSI 3.5%PRS 5.1%
-
CSI 1.7rCSI 32.6%PRS 25.4%
-
CSI 1.7rCSI 3.1%PRS 6.1%
-
CSI 1.7rCSI 9.2%PRS 13.1%
-
CSI 1.8rCSI 2.1%PRS 12.6%
-
CSI 1.8rCSI 2.4%PRS 10.1%
-
CSI 1.9rCSI 10.7%PRS 10.9%
-
CSI 1.9rCSI 47.8%PRS 24.9%
-
CSI 1.9rCSI 11.0%PRS 10.3%
-
CSI 1.9rCSI 4.4%PRS 6.1%
-
CSI 2.0rCSI 4.6%PRS 18.3%
-
CSI 2.0rCSI 1.6%PRS 10.4%
-
CSI 2.0rCSI 10.3%PRS 33.0%
-
CSI 2.1rCSI 4.3%PRS 11.4%
-
CSI 2.1rCSI 4.6%PRS 39.1%
-
CSI 2.1rCSI 2.7%PRS 11.0%
-
CSI 2.1rCSI 5.1%PRS 9.0%
-
CSI 2.2rCSI 55.4%PRS 38.9%
-
CSI 2.2rCSI 4.7%PRS 9.8%
-
CSI 2.2rCSI 13.1%PRS 16.7%
-
CSI 2.2rCSI 5.5%PRS 9.0%
-
CSI 2.2rCSI 3.8%PRS 15.4%
-
CSI 2.2rCSI 58.7%PRS 37.8%
-
CSI 2.3rCSI 2.8%PRS 10.4%
-
CSI 2.4rCSI 3.5%PRS 10.6%
-
CSI 2.4rCSI 14.1%PRS 36.4%
-
CSI 2.4rCSI 6.7%PRS 11.3%
-
CSI 2.4rCSI 4.6%PRS 8.9%
-
CSI 2.4rCSI 3.9%PRS 6.4%
-
CSI 2.4rCSI 19.5%PRS 31.8%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 4134233255
Symbol: ERH_HUMAN
Name: Enhancer of rudimentary homolog
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8786099
Title: Cloning and mapping of a novel human cDNA homologous to DROER, the enhancer of the Drosophila melanogaster rudimentary gene.
PubMed ID: 8786099
PubMed ID: 9074495
Title: The putative cell cycle gene, enhancer of rudimentary, encodes a highly conserved protein found in plants and animals.
PubMed ID: 9074495
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 16984396
Title: Human enhancer of rudimentary is a molecular partner of PDIP46/SKAR, a protein interacting with DNA polymerase delta and S6K1 and regulating cell growth.
PubMed ID: 16984396
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 23145069
Title: Identification and Functional Analysis of the erh1(+) Gene Encoding Enhancer of Rudimentary Homolog from the Fission Yeast Schizosaccharomyces pombe.
PubMed ID: 23145069
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25284789
Title: 5-Hydroxymethylcytosine plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex.
PubMed ID: 25284789
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 15794639
Title: Structure of the conserved transcriptional repressor enhancer of rudimentary homolog.
PubMed ID: 15794639
DOI: 10.1021/bi047785w
Sequence Information:
- Length: 104
- Mass: 12259
- Checksum: C609AFF7F63E5279
- Sequence:
MSHTILLVQP TKRPEGRTYA DYESVNECME GVCKMYEEHL KRMNPNSPSI TYDISQLFDF IDDLADLSCL VYRADTQTYQ PYNKDWIKEK IYVLLRRQAQ QAGK