Details for: EWSR1

Gene ID: 2130

Symbol: EWSR1

Ensembl ID: ENSG00000182944

Description: EWS RNA binding protein 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 402.2624
    Cell Significance Index: -62.5700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 243.4126
    Cell Significance Index: -61.7400
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 181.9163
    Cell Significance Index: -74.9400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 172.0708
    Cell Significance Index: -69.9100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 168.4732
    Cell Significance Index: -79.5400
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 149.6155
    Cell Significance Index: -76.9600
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 118.8187
    Cell Significance Index: -79.7300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 73.3705
    Cell Significance Index: -70.0500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 60.2941
    Cell Significance Index: -74.3400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 21.7574
    Cell Significance Index: -58.2900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 19.5994
    Cell Significance Index: -77.3400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 18.6784
    Cell Significance Index: -57.3700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 14.4065
    Cell Significance Index: -31.5300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 3.7508
    Cell Significance Index: 259.3900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 2.2856
    Cell Significance Index: 269.5400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 2.0851
    Cell Significance Index: 226.8000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.9036
    Cell Significance Index: 122.8100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.8695
    Cell Significance Index: 304.0500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.6687
    Cell Significance Index: 331.1500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.5993
    Cell Significance Index: 320.8200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.5389
    Cell Significance Index: 44.3400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.4634
    Cell Significance Index: 50.8500
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.2565
    Cell Significance Index: 26.3000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.2488
    Cell Significance Index: 225.1200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.2443
    Cell Significance Index: 32.7200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.1868
    Cell Significance Index: 32.3100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.1851
    Cell Significance Index: 33.1200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.1590
    Cell Significance Index: 142.5100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.1209
    Cell Significance Index: 1012.1300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.0970
    Cell Significance Index: 150.6500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.0444
    Cell Significance Index: 47.3400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.0309
    Cell Significance Index: 57.8500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.0197
    Cell Significance Index: 365.7400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.9572
    Cell Significance Index: 71.3400
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.9517
    Cell Significance Index: 27.9500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.9512
    Cell Significance Index: 519.4600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.9114
    Cell Significance Index: 630.3600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.8776
    Cell Significance Index: 112.5000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.8181
    Cell Significance Index: 361.6900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.7727
    Cell Significance Index: 36.3200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.7110
    Cell Significance Index: 37.3300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.7108
    Cell Significance Index: 15.4000
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.6991
    Cell Significance Index: 7.6000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.6526
    Cell Significance Index: 84.3200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.6120
    Cell Significance Index: 46.9700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4392
    Cell Significance Index: 43.4500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.3935
    Cell Significance Index: 11.2800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3051
    Cell Significance Index: 15.8500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2597
    Cell Significance Index: 49.4200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2217
    Cell Significance Index: 7.7900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.2049
    Cell Significance Index: 3.0700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1979
    Cell Significance Index: 33.8000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1810
    Cell Significance Index: 12.8000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.1778
    Cell Significance Index: 2.1200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1355
    Cell Significance Index: 8.5400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1139
    Cell Significance Index: 7.0000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1002
    Cell Significance Index: 4.6700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0961
    Cell Significance Index: 181.0300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0822
    Cell Significance Index: 52.1800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0474
    Cell Significance Index: 87.4300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0417
    Cell Significance Index: 64.1900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0343
    Cell Significance Index: 46.6900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0307
    Cell Significance Index: 0.8200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0045
    Cell Significance Index: -2.0400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0150
    Cell Significance Index: -11.3600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0298
    Cell Significance Index: -22.1000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0444
    Cell Significance Index: -32.5900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0609
    Cell Significance Index: -1.0200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0709
    Cell Significance Index: -44.3000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0799
    Cell Significance Index: -8.1600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0941
    Cell Significance Index: -53.0700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.1050
    Cell Significance Index: -1.9400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1772
    Cell Significance Index: -37.3200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2371
    Cell Significance Index: -15.9400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2392
    Cell Significance Index: -68.8200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2724
    Cell Significance Index: -39.6000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3555
    Cell Significance Index: -18.5200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3828
    Cell Significance Index: -43.8600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.3961
    Cell Significance Index: -7.7300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.4004
    Cell Significance Index: -45.7000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4092
    Cell Significance Index: -18.1000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4571
    Cell Significance Index: -14.6400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.4662
    Cell Significance Index: -54.3300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4907
    Cell Significance Index: -13.1300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.5602
    Cell Significance Index: -9.6000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.5865
    Cell Significance Index: -22.2100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.6040
    Cell Significance Index: -15.4300
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.6293
    Cell Significance Index: -14.5400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.6311
    Cell Significance Index: -8.6100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.6559
    Cell Significance Index: -68.3000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.7178
    Cell Significance Index: -18.4500
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.7671
    Cell Significance Index: -13.5600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.8802
    Cell Significance Index: -69.7100
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.9148
    Cell Significance Index: -7.4600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.1020
    Cell Significance Index: -67.5600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -1.1077
    Cell Significance Index: -23.5900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.2743
    Cell Significance Index: -34.1500
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -1.3514
    Cell Significance Index: -10.7900
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -1.3852
    Cell Significance Index: -29.6100
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -1.3868
    Cell Significance Index: -23.3600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** EWSR1 is a 70-kDa RNA binding protein that localizes to the nucleus and is characterized by its ability to bind to specific RNA sequences, thereby regulating gene expression. This protein exhibits high sequence homology to other RNA binding proteins, such as EWSR1-associated RNA binding protein (EWSRBP), and shares similarities with other transcriptional regulators, including the EWS/FLI-1 fusion protein, which is associated with Ewing's sarcoma. EWSR1 is also known to interact with various cellular proteins, including calmodulin, which modulates its activity. **Pathways and Functions:** EWSR1 is involved in multiple cellular pathways, including: 1. **Transcriptional regulation:** EWSR1 acts as a transcriptional regulator by binding to specific RNA sequences, thereby modulating gene expression. This protein is involved in the regulation of genes involved in cell cycle progression, DNA repair, and apoptosis. 2. **RNA processing:** EWSR1 is involved in the regulation of RNA processing, including splicing and degradation. This protein interacts with RNA-binding proteins, such as EWSRBP, to regulate RNA processing. 3. **Cellular differentiation:** EWSR1 plays a critical role in cellular differentiation, particularly in the development of immune cells, such as B cells and T cells. This protein regulates the expression of genes involved in immune cell development and function. 4. **DNA repair:** EWSR1 is involved in the regulation of DNA repair pathways, including non-homologous end joining (NHEJ) and homologous recombination (HR). **Clinical Significance:** EWSR1 is associated with several human diseases, including: 1. **Ewing's sarcoma:** EWSR1 is fused with the FLI-1 gene in Ewing's sarcoma, a type of bone cancer. This fusion protein is a potent transcriptional regulator that drives the expression of genes involved in tumor growth and survival. 2. **Leukemia:** EWSR1 is involved in the regulation of gene expression in leukemia cells, including acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). 3. **Immune disorders:** EWSR1 is involved in the regulation of immune cell development and function, and dysregulation of this protein has been implicated in autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. In conclusion, EWSR1 is a versatile RNA binding protein that plays a critical role in regulating gene expression and cellular differentiation. Its dysregulation has been implicated in various human diseases, including cancer and immune disorders, highlighting the importance of this protein in maintaining cellular homeostasis and function.

Genular Protein ID: 9976613

Symbol: EWS_HUMAN

Name: RNA-binding protein EWS

UniProtKB Accession Codes:

Q01844 B0QYK1 Q5THL0 Q92635 Q96FE8 Q96MN4 Q96MX4 Q9BWA2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 43 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 12 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 5 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 RefSeq 5 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1522903

Title: Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours.

PubMed ID: 1522903

DOI: 10.1038/359162a0

PubMed ID: 8307570

Title: Genomic structure of the EWS gene and its relationship to EWSR1, a site of tumor-associated chromosome translocation.

PubMed ID: 8307570

DOI: 10.1016/s0888-7543(05)80363-5

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8975699

Title: Identification of new members of the Gas2 and Ras families in the 22q12 chromosome region.

PubMed ID: 8975699

DOI: 10.1006/geno.1996.0625

PubMed ID: 11278906

Title: Exposure on cell surface and extensive arginine methylation of Ewing sarcoma (EWS) protein.

PubMed ID: 11278906

DOI: 10.1074/jbc.m011446200

PubMed ID: 7542907

Title: Molecular analysis of a t(11;22) translocation junction in a case of Ewing's sarcoma.

PubMed ID: 7542907

DOI: 10.1002/gcc.2870130209

PubMed ID: 9341188

Title: The prooncoprotein EWS binds calmodulin and is phosphorylated by protein kinase C through an IQ domain.

PubMed ID: 9341188

DOI: 10.1074/jbc.272.43.27369

PubMed ID: 8401579

Title: EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts.

PubMed ID: 8401579

DOI: 10.1038/ng0893-341

PubMed ID: 8084618

Title: The EWS gene, involved in Ewing family of tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors, codes for an RNA binding protein with novel regulatory domains.

PubMed ID: 8084618

PubMed ID: 7539287

Title: Fusion of the EWS gene to a DNA segment from 9q22-31 in a human myxoid chondrosarcoma.

PubMed ID: 7539287

DOI: 10.1002/gcc.2870120412

PubMed ID: 7700648

Title: A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1.

PubMed ID: 7700648

PubMed ID: 7862627

Title: Characterization of the genomic breakpoint and chimeric transcripts in the EWS-WT1 gene fusion of desmoplastic small round cell tumor.

PubMed ID: 7862627

DOI: 10.1073/pnas.92.4.1028

PubMed ID: 9121764

Title: A new member of the ETS family fused to EWS in Ewing tumors.

PubMed ID: 9121764

DOI: 10.1038/sj.onc.1200933

PubMed ID: 9660765

Title: The transcriptional repressor ZFM1 interacts with and modulates the ability of EWS to activate transcription.

PubMed ID: 9660765

DOI: 10.1074/jbc.273.29.18086

PubMed ID: 10767297

Title: Transcriptional activation by the Ewing's sarcoma (EWS) oncogene can be cis-repressed by the EWS RNA-binding domain.

PubMed ID: 10767297

DOI: 10.1074/jbc.m002961200

PubMed ID: 10949935

Title: A novel zinc finger gene is fused to EWS in small round cell tumor.

PubMed ID: 10949935

DOI: 10.1038/sj.onc.1203762

PubMed ID: 15044653

Title: A patient with two Ewing's sarcomas with distinct EWS fusion transcripts.

PubMed ID: 15044653

DOI: 10.1056/nejmc032965

PubMed ID: 17172842

Title: Expression of EWS-ETS fusions in NIH3T3 cells reveals significant differences to Ewing's sarcoma.

PubMed ID: 17172842

DOI: 10.4161/cc.5.23.3505

PubMed ID: 16965792

Title: Identification and characterization of the nuclear localization/retention signal in the EWS proto-oncoprotein.

PubMed ID: 16965792

DOI: 10.1016/j.jmb.2006.08.018

PubMed ID: 18632687

Title: TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules.

PubMed ID: 18632687

DOI: 10.1093/hmg/ddn203

PubMed ID: 18320585

Title: Identification of proteins interacting with protein arginine methyltransferase 8: the Ewing sarcoma (EWS) protein binds independent of its methylation state.

PubMed ID: 18320585

DOI: 10.1002/prot.22004

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 15884099

Title: Fusion of the EWSR1 and ATF1 genes without expression of the MITF-M transcript in angiomatoid fibrous histiocytoma.

PubMed ID: 15884099

DOI: 10.1002/gcc.20201

PubMed ID: 17724745

Title: EWSR1-CREB1 is the predominant gene fusion in angiomatoid fibrous histiocytoma.

PubMed ID: 17724745

DOI: 10.1002/gcc.20491

Sequence Information:

  • Length: 656
  • Mass: 68478
  • Checksum: 0DA02CEE146720BB
  • Sequence:
    • MASTDYSTYS QAAAQQGYSA YTAQPTQGYA QTTQAYGQQS YGTYGQPTDV SYTQAQTTAT 
YGQTAYATSY GQPPTGYTTP TAPQAYSQPV QGYGTGAYDT TTATVTTTQA SYAAQSAYGT 
QPAYPAYGQQ PAATAPTRPQ DGNKPTETSQ PQSSTGGYNQ PSLGYGQSNY SYPQVPGSYP 
MQPVTAPPSY PPTSYSSTQP TSYDQSSYSQ QNTYGQPSSY GQQSSYGQQS SYGQQPPTSY 
PPQTGSYSQA PSQYSQQSSS YGQQSSFRQD HPSSMGVYGQ ESGGFSGPGE NRSMSGPDNR 
GRGRGGFDRG GMSRGGRGGG RGGMGSAGER GGFNKPGGPM DEGPDLDLGP PVDPDEDSDN 
SAIYVQGLND SVTLDDLADF FKQCGVVKMN KRTGQPMIHI YLDKETGKPK GDATVSYEDP 
PTAKAAVEWF DGKDFQGSKL KVSLARKKPP MNSMRGGLPP REGRGMPPPL RGGPGGPGGP 
GGPMGRMGGR GGDRGGFPPR GPRGSRGNPS GGGNVQHRAG DWQCPNPGCG NQNFAWRTEC 
NQCKAPKPEG FLPPPFPPPG GDRGRGGPGG MRGGRGGLMD RGGPGGMFRG GRGGDRGGFR 
GGRGMDRGGF GGGRRGGPGG PPGPLMEQMG GRRGGRGGPG KMDKGEHRQE RRDRPY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.