Details for: FANCB
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 36.4203
Cell Significance Index: -5.6700 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 33.2356
Cell Significance Index: -8.4300 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 18.6335
Cell Significance Index: -7.5700 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 7.9184
Cell Significance Index: -7.5600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 7.1414
Cell Significance Index: -8.8100 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 3.3335
Cell Significance Index: -8.9300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.3208
Cell Significance Index: 28.1300 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.8523
Cell Significance Index: 84.3100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.6077
Cell Significance Index: 34.1000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.4920
Cell Significance Index: 80.0200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.4341
Cell Significance Index: 47.2200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.3383
Cell Significance Index: 20.3100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.2891
Cell Significance Index: 7.7200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.2865
Cell Significance Index: 56.8500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.2653
Cell Significance Index: 31.2900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2567
Cell Significance Index: 48.8500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.2068
Cell Significance Index: 5.7800 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.1972
Cell Significance Index: 5.2800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.1906
Cell Significance Index: 38.2400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0806
Cell Significance Index: 35.6300 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0626
Cell Significance Index: 4.4300 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0599
Cell Significance Index: 21.5000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0560
Cell Significance Index: 30.5900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0541
Cell Significance Index: 1.5600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0425
Cell Significance Index: 7.6700 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.0373
Cell Significance Index: 33.7100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0365
Cell Significance Index: 2.5300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0145
Cell Significance Index: 1.7800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0136
Cell Significance Index: 0.3400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0082
Cell Significance Index: 0.3800 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0057
Cell Significance Index: 3.9700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0042
Cell Significance Index: 6.4600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0036
Cell Significance Index: 6.7700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0035
Cell Significance Index: 6.4400 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.0022
Cell Significance Index: 0.1400 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0010
Cell Significance Index: -0.0200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0014
Cell Significance Index: -0.0300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0024
Cell Significance Index: -0.1100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0028
Cell Significance Index: -0.1000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0047
Cell Significance Index: -3.0000 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0078
Cell Significance Index: -10.5900 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0109
Cell Significance Index: -8.0200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0117
Cell Significance Index: -8.8800 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0123
Cell Significance Index: -1.5800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0132
Cell Significance Index: -1.9200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0148
Cell Significance Index: -2.0300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0155
Cell Significance Index: -11.4900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0156
Cell Significance Index: -0.6900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0165
Cell Significance Index: -7.4900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0169
Cell Significance Index: -0.2900 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0200
Cell Significance Index: -5.7600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0201
Cell Significance Index: -11.3600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0218
Cell Significance Index: -1.1400 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0227
Cell Significance Index: -0.8600 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0343
Cell Significance Index: -0.7500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0355
Cell Significance Index: -4.1400 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: -0.0358
Cell Significance Index: -0.2600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0394
Cell Significance Index: -2.6500 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0425
Cell Significance Index: -2.6100 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0430
Cell Significance Index: -0.9000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0476
Cell Significance Index: -8.1300 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0550
Cell Significance Index: -7.1100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0574
Cell Significance Index: -12.0900 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.0607
Cell Significance Index: -0.6600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0649
Cell Significance Index: -6.6300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0722
Cell Significance Index: -8.2700 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0731
Cell Significance Index: -2.3400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0832
Cell Significance Index: -8.6600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0837
Cell Significance Index: -5.1300 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0920
Cell Significance Index: -4.7900 - Cell Name: melanocyte of skin (CL1000458)
Fold Change: -0.0931
Cell Significance Index: -1.3100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0935
Cell Significance Index: -4.4000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0999
Cell Significance Index: -7.4500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1063
Cell Significance Index: -8.4200 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1080
Cell Significance Index: -2.7600 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1150
Cell Significance Index: -7.2500 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1154
Cell Significance Index: -4.0100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1168
Cell Significance Index: -8.9600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1202
Cell Significance Index: -3.0900 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: -0.1557
Cell Significance Index: -2.1600 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.1581
Cell Significance Index: -4.2400 - Cell Name: proerythroblast (CL0000547)
Fold Change: -0.1584
Cell Significance Index: -2.2700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1672
Cell Significance Index: -8.7800 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.1772
Cell Significance Index: -2.6700 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.1792
Cell Significance Index: -1.7100 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1881
Cell Significance Index: -5.9900 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1931
Cell Significance Index: -5.2600 - Cell Name: helper T cell (CL0000912)
Fold Change: -0.1967
Cell Significance Index: -2.8000 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.1992
Cell Significance Index: -1.3500 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.2032
Cell Significance Index: -5.8000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2036
Cell Significance Index: -6.6700 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.2051
Cell Significance Index: -2.3300 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.2052
Cell Significance Index: -7.1900 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.2073
Cell Significance Index: -3.4700 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.2225
Cell Significance Index: -6.5600 - Cell Name: radial glial cell (CL0000681)
Fold Change: -0.2351
Cell Significance Index: -1.4000 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: -0.2500
Cell Significance Index: -2.8300 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.2530
Cell Significance Index: -7.4300 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2539
Cell Significance Index: -12.8300 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.2549
Cell Significance Index: -3.6500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 875977352
Symbol: FANCB_HUMAN
Name: Fanconi anemia group B protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15502827
Title: X-linked inheritance of Fanconi anemia complementation group B.
PubMed ID: 15502827
DOI: 10.1038/ng1458
PubMed ID: 16116422
Title: A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M.
PubMed ID: 16116422
DOI: 10.1038/ng1626
PubMed ID: 16679491
Title: Fanconi anaemia complementation group B presenting as X linked VACTERL with hydrocephalus syndrome.
PubMed ID: 16679491
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23033978
Title: Diagnostic exome sequencing in persons with severe intellectual disability.
PubMed ID: 23033978
Sequence Information:
- Length: 859
- Mass: 97726
- Checksum: 6CECD725B63C3901
- Sequence:
MTSKQAMSSN EQERLLCYNG EVLVFQLSKG NFADKEPTKT PILHVRRMVF DRGTKVFVQK STGFFTIKEE NSHLKIMCCN CVSDFRTGIN LPYIVIEKNK KNNVFEYFLL ILHSTNKFEM RLSFKLGYEM KDGLRVLNGP LILWRHVKAF FFISSQTGKV VSVSGNFSSI QWAGEIENLG MVLLGLKECC LSEEECTQEP SKSDYAIWNT KFCVYSLESQ EVLSDIYIIP PAYSSVVTYV HICATEIIKN QLRISLIALT RKNQLISFQN GTPKNVCQLP FGDPCAVQLM DSGGGNLFFV VSFISNNACA VWKESFQVAA KWEKLSLVLI DDFIGSGTEQ VLLLFKDSLN SDCLTSFKIT DLGKINYSSE PSDCNEDDLF EDKQENRYLV VPPLETGLKV CFSSFRELRQ HLLLKEKIIS KSYKALINLV QGKDDNTSSA EEKECLVPLC GEEENSVHIL DEKLSDNFQD SEQLVEKIWY RVIDDSLVVG VKTTSSLKLS LNDVTLSLLM DQAHDSRFRL LKCQNRVIKL STNPFPAPYL MPCEIGLEAK RVTLTPDSKK EESFVCEHPS KKECVQIITA VTSLSPLLTF SKFCCTVLLQ IMERESGNCP KDRYVVCGRV FLSLEDLSTG KYLLTFPKKK PIEHMEDLFA LLAAFHKSCF QITSPGYALN SMKVWLLEHM KCEIIKEFPE VYFCERPGSF YGTLFTWKQR TPFEGILIIY SRNQTVMFQC LHNLIRILPI NCFLKNLKSG SENFLIDNMA FTLEKELVTL SSLSSAIAKH ESNFMQRCEV SKGKSSVVAA ALSDRRENIH PYRKELQREK KKMLQTNLKV SGALYREITL KVAEVQLKSD FAAQKLSNL
Genular Protein ID: 2000015413
Symbol: C9J5X9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 15772651
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
Sequence Information:
- Length: 832
- Mass: 94822
- Checksum: AF04B8BA52351553
- Sequence:
MTSKQAMSSN EQERLLCYNG EVLVFQLSKG NFADKEPTKT PILHVRRMVF DRGTKVFVQK STGFFTIKEE NSHLKIMCCN CVSDFRTGIN LPYIVIEKNK KNNVFEYFLL ILHSTNKFEM RLSFKLGYEM KDGLRVLNGP LILWRHVKAF FFISSQTGKV VSVSGNFSSI QWAGEIENLG MVLLGLKECC LSEEECTQEP SKSDYAIWNT KFCVYSLESQ EVLSDIYIIP PAYSSVVTYV HICATEIIKN QLRISLIALT RKNQLISFQN GTPKNVCQLP FGDPCAVQLM DSGGGNLFFV VSFISNNACA VWKESFQVAA KWEKLSLVLI DDFIGSGTEQ VLLLFKDSLN SDCLTSFKIT DLGKINYSSE PSDCNEDDLF EDKQENRYLV VPPLETGLKV CFSSFRELRQ HLLLKEKIIS KSYKALINLV QGKDDNTSSA EEKECLVPLC GEEENSVHIL DEKLSDNFQD SEQLVEKIWY RVIDDSLVVG VKTTSSLKLS LNDVTLSLLM DQAHDSRFRL LKCQNRVIKL STNPFPAPYL MPCEIGLEAK RVTLTPDSKK EESFVCEHPS KKECVQIITA VTSLSPLLTF SKFCCTVLLQ IMERESGNCP KDRYVVCGRV FLSLEDLSTG KYLLTFPKKK PIEHMEDLFA LLAAFHKSCF QITSPGYALN SMKVWLLEHM KCEIIKEFPE VYFCERPGSF YGTLFTWKQR TPFEGILIIY SRNQTVMFQC LHNLIRILPI NCFLKNLKSG SENFLIDNMA FTLEKELVTL SSLSSAIAKH ESNFMQRCEV SKGKSSVVAA ALSDRRENIH PYRKELQREK KKMLQTNLKW PS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.