Details for: FER
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: Purkinje cell (CL0000121)
Fold Change: 4.88
Marker Score: 164945 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 3.99
Marker Score: 5366 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 3.64
Marker Score: 4402 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 3.45
Marker Score: 18094 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 3.38
Marker Score: 7411 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 3.34
Marker Score: 4162 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 3.22
Marker Score: 13496 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 2.98
Marker Score: 13783 - Cell Name: renal principal cell (CL0005009)
Fold Change: 2.84
Marker Score: 2185 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 2.83
Marker Score: 5437 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 2.82
Marker Score: 3974 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 2.81
Marker Score: 59900 - Cell Name: granule cell (CL0000120)
Fold Change: 2.79
Marker Score: 21035 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 2.77
Marker Score: 11538.5 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 2.77
Marker Score: 1538 - Cell Name: stellate neuron (CL0000122)
Fold Change: 2.71
Marker Score: 14556 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 2.71
Marker Score: 9083 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 2.69
Marker Score: 1338 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 2.68
Marker Score: 2317 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 2.68
Marker Score: 783 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 2.67
Marker Score: 3075 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.61
Marker Score: 20033 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.58
Marker Score: 51346 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 2.57
Marker Score: 1493 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 2.57
Marker Score: 1934 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.56
Marker Score: 97327 - Cell Name: contractile cell (CL0000183)
Fold Change: 2.54
Marker Score: 1374 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.53
Marker Score: 37868 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 2.53
Marker Score: 1332 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.49
Marker Score: 10335 - Cell Name: macroglial cell (CL0000126)
Fold Change: 2.49
Marker Score: 5720 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 2.48
Marker Score: 2366 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 2.37
Marker Score: 5673 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.35
Marker Score: 86788 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 2.32
Marker Score: 1354 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 2.32
Marker Score: 973 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 2.3
Marker Score: 731 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 2.28
Marker Score: 1500 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 2.28
Marker Score: 822.5 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 2.27
Marker Score: 6483 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 2.2
Marker Score: 696 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.19
Marker Score: 8455 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 2.18
Marker Score: 1275 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 2.17
Marker Score: 2457 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 2.17
Marker Score: 1215 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 2.15
Marker Score: 20202 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 2.13
Marker Score: 820 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 2.11
Marker Score: 2330.5 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 2.1
Marker Score: 1252 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 2.05
Marker Score: 3450 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.04
Marker Score: 125552 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 2.02
Marker Score: 973 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 2
Marker Score: 1318 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.93
Marker Score: 19922 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 1.92
Marker Score: 698 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.92
Marker Score: 34067 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.91
Marker Score: 18109 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.86
Marker Score: 29874 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.84
Marker Score: 15768 - Cell Name: sympathetic neuron (CL0011103)
Fold Change: 1.83
Marker Score: 606 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 1.83
Marker Score: 1625 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.83
Marker Score: 1583 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 1.81
Marker Score: 2237 - Cell Name: skin fibroblast (CL0002620)
Fold Change: 1.8
Marker Score: 467 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 1.79
Marker Score: 885 - Cell Name: neuron (CL0000540)
Fold Change: 1.77
Marker Score: 7215 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 1.76
Marker Score: 2200 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.76
Marker Score: 482 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.75
Marker Score: 1887 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 1.74
Marker Score: 38916 - Cell Name: fat cell (CL0000136)
Fold Change: 1.71
Marker Score: 955 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 1.68
Marker Score: 1798.5 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.6
Marker Score: 2476 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 1.6
Marker Score: 6667 - Cell Name: podocyte (CL0000653)
Fold Change: 1.6
Marker Score: 591 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: 1.57
Marker Score: 686 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 1.56
Marker Score: 1084 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 1.54
Marker Score: 580 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: 1.51
Marker Score: 5827 - Cell Name: germ cell (CL0000586)
Fold Change: 1.46
Marker Score: 2558 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 1.46
Marker Score: 2127 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 1.44
Marker Score: 414 - Cell Name: ganglion interneuron (CL0000397)
Fold Change: 1.43
Marker Score: 435 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 1.4
Marker Score: 356 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.36
Marker Score: 427 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 1.33
Marker Score: 4732.5 - Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 1.33
Marker Score: 485 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 1.33
Marker Score: 1089 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.31
Marker Score: 788 - Cell Name: mesangial cell (CL0000650)
Fold Change: 1.31
Marker Score: 1578 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 1.27
Marker Score: 4515.5 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 1.27
Marker Score: 432 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.27
Marker Score: 2989 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.25
Marker Score: 403 - Cell Name: endocrine cell (CL0000163)
Fold Change: 1.25
Marker Score: 647 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 1.23
Marker Score: 1739 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.23
Marker Score: 19208 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 1.2
Marker Score: 449.5 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.17
Marker Score: 2372 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 1.16
Marker Score: 368
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Other Information
Genular Protein ID: 567500370
Symbol: FER_HUMAN
Name: Tyrosine-protein kinase Fer
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2725517
Title: Isolation and sequence analysis of a novel human tyrosine kinase gene.
PubMed ID: 2725517
PubMed ID: 22223638
Title: Intronic promoter drives the BORIS-regulated expression of FerT in colon carcinoma cells.
PubMed ID: 22223638
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 8247543
Title: A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes.
PubMed ID: 8247543
PubMed ID: 2156206
Title: Identification and chromosomal mapping of new human tyrosine kinase genes.
PubMed ID: 2156206
PubMed ID: 1990274
Title: Nuclear and cytoplasmic location of the FER tyrosine kinase.
PubMed ID: 1990274
PubMed ID: 7623846
Title: The cytoplasmic tyrosine kinase FER is associated with the catenin-like substrate pp120 and is activated by growth factors.
PubMed ID: 7623846
PubMed ID: 9722593
Title: Growth factor-dependent phosphorylation of the actin-binding protein cortactin is mediated by the cytoplasmic tyrosine kinase FER.
PubMed ID: 9722593
PubMed ID: 12972546
Title: Identification of Fer tyrosine kinase localized on microtubules as a platelet endothelial cell adhesion molecule-1 phosphorylating kinase in vascular endothelial cells.
PubMed ID: 12972546
PubMed ID: 14517306
Title: Tyrosine phosphorylation of plakoglobin causes contrary effects on its association with desmosomes and adherens junction components and modulates beta-catenin-mediated transcription.
PubMed ID: 14517306
PubMed ID: 16418535
Title: Coordination between the actin cytoskeleton and membrane deformation by a novel membrane tubulation domain of PCH proteins is involved in endocytosis.
PubMed ID: 16418535
PubMed ID: 18985748
Title: Expression of Fer testis (FerT) tyrosine kinase transcript variants and distribution sites of FerT during the development of the acrosome-acroplaxome-manchette complex in rat spermatids.
PubMed ID: 18985748
DOI: 10.1002/dvdy.21789
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 19339212
Title: Specific tyrosine phosphorylation of focal adhesion kinase mediated by Fer tyrosine kinase in suspended hepatocytes.
PubMed ID: 19339212
PubMed ID: 19159681
Title: Hsp90 and a tyrosine embedded in the Hsp90 recognition loop are required for the Fer tyrosine kinase activity.
PubMed ID: 19159681
PubMed ID: 19147545
Title: The Fer tyrosine kinase cooperates with interleukin-6 to activate signal transducer and activator of transcription 3 and promote human prostate cancer cell growth.
PubMed ID: 19147545
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19738202
Title: The tyrosine kinase Fer is a downstream target of the PLD-PA pathway that regulates cell migration.
PubMed ID: 19738202
PubMed ID: 20111072
Title: FES kinases are required for oncogenic FLT3 signaling.
PubMed ID: 20111072
DOI: 10.1038/leu.2009.301
PubMed ID: 21518868
Title: FER tyrosine kinase (FER) overexpression mediates resistance to quinacrine through EGF-dependent activation of NF-kappaB.
PubMed ID: 21518868
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 11994747
Title: Closing in on the biological functions of Fps/Fes and Fer.
PubMed ID: 11994747
DOI: 10.1038/nrm783
PubMed ID: 1651563
Title: Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients.
PubMed ID: 1651563
PubMed ID: 17344846
Title: Patterns of somatic mutation in human cancer genomes.
PubMed ID: 17344846
DOI: 10.1038/nature05610
Sequence Information:
- Length: 822
- Mass: 94638
- Checksum: BD42DF6C03419C76
- Sequence:
MGFGSDLKNS HEAVLKLQDW ELRLLETVKK FMALRIKSDK EYASTLQNLC NQVDKESTVQ MNYVSNVSKS WLLMIQQTEQ LSRIMKTHAE DLNSGPLHRL TMMIKDKQQV KKSYIGVHQQ IEAEMIKVTK TELEKLKCSY RQLIKEMNSA KEKYKEALAK GKETEKAKER YDKATMKLHM LHNQYVLALK GAQLHQNQYY DITLPLLLDS LQKMQEEMIK ALKGIFDEYS QITSLVTEEI VNVHKEIQMS VEQIDPSTEY NNFIDVHRTT AAKEQEIEFD TSLLEENENL QANEIMWNNL TAESLQVMLK TLAEELMQTQ QMLLNKEEAV LELEKRIEES SETCEKKSDI VLLLSQKQAL EELKQSVQQL RCTEAKFSAQ KELLEQKVQE NDGKEPPPVV NYEEDARSVT SMERKERLSK FESIRHSIAG IIRSPKSALG SSALSDMISI SEKPLAEQDW YHGAIPRIEA QELLKKQGDF LVRESHGKPG EYVLSVYSDG QRRHFIIQYV DNMYRFEGTG FSNIPQLIDH HYTTKQVITK KSGVVLLNPI PKDKKWILSH EDVILGELLG KGNFGEVYKG TLKDKTSVAV KTCKEDLPQE LKIKFLQEAK ILKQYDHPNI VKLIGVCTQR QPVYIIMELV SGGDFLTFLR RKKDELKLKQ LVKFSLDAAA GMLYLESKNC IHRDLAARNC LVGENNVLKI SDFGMSRQED GGVYSSSGLK QIPIKWTAPE ALNYGRYSSE SDVWSFGILL WETFSLGVCP YPGMTNQQAR EQVERGYRMS APQHCPEDIS KIMMKCWDYK PENRPKFSEL QKELTIIKRK LT
Genular Protein ID: 2830150207
Symbol: Q6PEJ9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 163
- Mass: 18865
- Checksum: 651BF0961098ECCE
- Sequence:
MGFGSDLKNS HEAVLKLQDW ELRLLETVKK FMALRIKSDK EYASTLQNLC NQVDKGSTVQ MNYVSNVSKS WLLMIQQTEQ LSRIMKTHAE DLNSGPLHRL TMMIKDKQQV KKSYIGVHQQ IEAEMIKVTK TELEKLKCSY RQLIKEMNSA KGKYKEALAK VKK
Genular Protein ID: 582616497
Symbol: W0S1B5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 647
- Mass: 74266
- Checksum: F05F6497716D7D36
- Sequence:
MKLHMLHNQY VLALKGAQLH QNQYYDITLP LLLDSLQKMQ EEMIKALKGI FDEYSQITSL VTEEIVNVHK EIQMSVEQID PSTEYNNFID VHRTTAAKEQ EIEFDTSLLE ENENLQANEI MWNNLTAESL QVMLKTLAEE LMQTQQMLLN KEEAVLELEK RIEESSETCE KKSDIVLLLS QKQALEELKQ SVQQLRCTEA KFSAQKELLE QKVQENDGKE PPPVVNYEED ARSVTSMERK ERLSKFESIR HSIAGIIRSP KSALGSSALS DMISISEKPL AEQDWYHGAI PRIEAQELLK KQGDFLVRES HGKPGEYVLS VYSDGQRRHF IIQYVDNMYR FEGTGFSNIP QLIDHHYTTK QVITKKSGVV LLNPIPKDKK WILSHEDVIL GELLGKGNFG EVYKGTLKDK TSVAVKTCKE DLPQELKIKF LQEAKILKQY DHPNIVKLIG VCTQRQPVYI IMELVSGGDF LTFLRRKKDE LKLKQLVKFS LDAAAGMLYL ESKNCIHRDL AARNCLVGEN NVLKISDFGM SRQEDGGVYS SSGLKQIPIK WTAPEALNYG RYSSESDVWS FGILLWETFS LGVCPYPGMT NQQAREQVER GYRMSAPQHC PEDISKIMMK CWDYKPENRP KFSELQKELT IIKRKLT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.