Details for: ELP4
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 277.6684
Cell Significance Index: -43.1900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 168.1100
Cell Significance Index: -42.6400 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 119.5844
Cell Significance Index: -49.2600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 95.3989
Cell Significance Index: -45.0400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 89.1800
Cell Significance Index: -36.2300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 36.3841
Cell Significance Index: -44.8600 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 15.3349
Cell Significance Index: -41.0800 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 12.3166
Cell Significance Index: -37.8300 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 11.4444
Cell Significance Index: -45.1600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 11.0528
Cell Significance Index: -24.1900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 7.1462
Cell Significance Index: 122.4700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 5.3916
Cell Significance Index: 302.5500 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 4.3211
Cell Significance Index: 53.6000 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 2.7256
Cell Significance Index: 58.2600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 2.5622
Cell Significance Index: 253.4600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.0615
Cell Significance Index: 739.4100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.0433
Cell Significance Index: 409.8900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 2.0337
Cell Significance Index: 1406.5600 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 1.8839
Cell Significance Index: 71.3400 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 1.7942
Cell Significance Index: 79.3600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.7600
Cell Significance Index: 3313.7900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1.6340
Cell Significance Index: 2515.4400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.5459
Cell Significance Index: 306.7900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.4998
Cell Significance Index: 115.0900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.4046
Cell Significance Index: 228.4500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 1.3277
Cell Significance Index: 2448.6600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.2869
Cell Significance Index: 1161.9400 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: 1.1964
Cell Significance Index: 16.7300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.0542
Cell Significance Index: 29.4600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 1.0245
Cell Significance Index: 62.9700 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.9832
Cell Significance Index: 23.5800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.8342
Cell Significance Index: 56.0900 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.8131
Cell Significance Index: 15.8700 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.6441
Cell Significance Index: 18.3800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.6009
Cell Significance Index: 381.6100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.4872
Cell Significance Index: 56.7800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.3642
Cell Significance Index: 16.5100 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: 0.3082
Cell Significance Index: 3.2100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.2902
Cell Significance Index: 30.2200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.2597
Cell Significance Index: 353.0800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2590
Cell Significance Index: 17.9100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.2556
Cell Significance Index: 46.0900 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.2480
Cell Significance Index: 3.5300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2044
Cell Significance Index: 5.8900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.2008
Cell Significance Index: 4.3500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.1938
Cell Significance Index: 87.9700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.1278
Cell Significance Index: 15.7100 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: 0.1127
Cell Significance Index: 1.4100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0971
Cell Significance Index: 42.9500 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0692
Cell Significance Index: 37.8000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.0579
Cell Significance Index: 3.6500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0008
Cell Significance Index: -0.1000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0045
Cell Significance Index: -0.1200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0062
Cell Significance Index: -0.9000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0099
Cell Significance Index: -1.6900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0272
Cell Significance Index: -20.1800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0340
Cell Significance Index: -24.9100 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0381
Cell Significance Index: -23.8000 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0507
Cell Significance Index: -28.6200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0605
Cell Significance Index: -45.7900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0723
Cell Significance Index: -9.9300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0953
Cell Significance Index: -4.9500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: -0.1234
Cell Significance Index: -23.4800 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.1250
Cell Significance Index: -1.4900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1335
Cell Significance Index: -28.1200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1346
Cell Significance Index: -38.7400 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1579
Cell Significance Index: -5.5500 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1619
Cell Significance Index: -20.7600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1913
Cell Significance Index: -19.5400 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.2146
Cell Significance Index: -27.7200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.2174
Cell Significance Index: -5.8300 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.2385
Cell Significance Index: -3.0100 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.2457
Cell Significance Index: -3.3500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2630
Cell Significance Index: -13.8100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.2794
Cell Significance Index: -5.9500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2827
Cell Significance Index: -32.3900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.3000
Cell Significance Index: -19.3600 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.3010
Cell Significance Index: -6.5900 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.3235
Cell Significance Index: -22.8800 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.3365
Cell Significance Index: -8.2100 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.3652
Cell Significance Index: -5.2500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.3683
Cell Significance Index: -17.1700 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.4006
Cell Significance Index: -29.8600 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.4029
Cell Significance Index: -45.9900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.4089
Cell Significance Index: -19.2200 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.4098
Cell Significance Index: -6.0500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.4451
Cell Significance Index: -11.4400 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.4533
Cell Significance Index: -6.5200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.4621
Cell Significance Index: -36.6000 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.5801
Cell Significance Index: -10.0300 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.5929
Cell Significance Index: -14.8200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.5999
Cell Significance Index: -36.7800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.6177
Cell Significance Index: -13.1100 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.6259
Cell Significance Index: -32.6000 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: -0.6657
Cell Significance Index: -4.8400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.6857
Cell Significance Index: -21.8400 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.6953
Cell Significance Index: -13.9600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.7181
Cell Significance Index: -23.5100 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.7556
Cell Significance Index: -14.9400 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.7639
Cell Significance Index: -10.1900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3624983799
Symbol: ELP4_HUMAN
Name: Elongator complex protein 4
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11230166
Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.
PubMed ID: 11230166
DOI: 10.1101/gr.gr1547r
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11889558
Title: Characterization of a novel gene adjacent to PAX6, revealing synteny conservation with functional significance.
PubMed ID: 11889558
PubMed ID: 11714725
Title: Purification and characterization of the human elongator complex.
PubMed ID: 11714725
PubMed ID: 11818576
Title: Human Elongator facilitates RNA polymerase II transcription through chromatin.
PubMed ID: 11818576
PubMed ID: 16713582
Title: Transcription impairment and cell migration defects in elongator-depleted cells: implication for familial dysautonomia.
PubMed ID: 16713582
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22854966
Title: DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator.
PubMed ID: 22854966
PubMed ID: 24290376
Title: Disruption of autoregulatory feedback by a mutation in a remote, ultraconserved PAX6 enhancer causes aniridia.
PubMed ID: 24290376
PubMed ID: 29332244
Title: Structural insights into the function of Elongator.
PubMed ID: 29332244
Sequence Information:
- Length: 424
- Mass: 46588
- Checksum: A044C964F7C91E73
- Sequence:
MAAVATCGSV AASTGSAVAT ASKSNVTSFQ RRGPRASVTN DSGPRLVSIA GTRPSVRNGQ LLVSTGLPAL DQLLGGGLAV GTVLLIEEDK YNIYSPLLFK YFLAEGIVNG HTLLVASAKE DPANILQELP APLLDDKCKK EFDEDVYNHK TPESNIKMKI AWRYQLLPKM EIGPVSSSRF GHYYDASKRM PQELIEASNW HGFFLPEKIS STLKVEPCSL TPGYTKLLQF IQNIIYEEGF DGSNPQKKQR NILRIGIQNL GSPLWGDDIC CAENGGNSHS LTKFLYVLRG LLRTSLSACI ITMPTHLIQN KAIIARVTTL SDVVVGLESF IGSERETNPL YKDYHGLIHI RQIPRLNNLI CDESDVKDLA FKLKRKLFTI ERLHLPPDLS DTVSRSSKMD LAESAKRLGP GCGMMAGGKK HLDF
Genular Protein ID: 3018237540
Symbol: G5E9D4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11181995
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
Sequence Information:
- Length: 535
- Mass: 58833
- Checksum: 892DAD8B52F5E526
- Sequence:
MAAVATCGSV AASTGSAVAT ASKSNVTSFQ RRGPRASVTN DSGPRLVSIA GTRPSVRNGQ LLVSTGLPAL DQLLGGGLAV GTVLLIEEDK YNIYSPLLFK YFLAEGIVNG HTLLVASAKE DPANILQELP APLLDDKCKK EFDEDVYNHK TPESNIKMKI AWRYQLLPKM EIGPVSSSRF GHYYDASKRM PQELIEASNW HGFFLPEKIS STLKVEPCSL TPGYTKLLQF IQNIIYEEGF DGSNPQKKQR NILRIGIQNL GSPLWGDDIC CAENGGNSHS LTKFLYVLRG LLRTSLSACI ITMPTHLIQN KAIIARVTTL SDVVVGLESF IGSERETNPL YKDYHGLIHI RQIPRLNNLI CDESDVKDLA FKLKRKLFTI EAGVQWHDLG SRQPRLLGSS NSPASASLVA GITGAHHHTQ LIFVFLVEMG FHHVGQAGLE LLTSGDSSAS ASQSAGITGM SYRARPRALY FKENKSKVGA RQLLETREEH LSSRLLILTQ AERLCMGRRF FTAFHIFNEL PCKGDCICLQ TCQTQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.