Details for: AKAP8L

Gene ID: 26993

Symbol: AKAP8L

Ensembl ID: ENSG00000011243

Description: A-kinase anchoring protein 8 like

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 312.5136
    Cell Significance Index: -48.6100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 195.6290
    Cell Significance Index: -49.6200
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 138.2943
    Cell Significance Index: -56.9700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 104.8597
    Cell Significance Index: -42.6000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 96.7952
    Cell Significance Index: -49.7900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 45.0488
    Cell Significance Index: -43.0100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 40.4232
    Cell Significance Index: -49.8400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 17.8061
    Cell Significance Index: -47.7000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 14.6510
    Cell Significance Index: -45.0000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 13.2968
    Cell Significance Index: -52.4700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.4787
    Cell Significance Index: -20.7500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.1651
    Cell Significance Index: 434.3200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.0427
    Cell Significance Index: 27.8700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.8140
    Cell Significance Index: 94.4900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.3656
    Cell Significance Index: 71.7000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.2886
    Cell Significance Index: 255.7200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.2783
    Cell Significance Index: 458.5100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.2044
    Cell Significance Index: 53.2800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.1651
    Cell Significance Index: 89.4100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.0442
    Cell Significance Index: 722.1800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.9766
    Cell Significance Index: 36.9800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.9558
    Cell Significance Index: 64.2700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.9537
    Cell Significance Index: 43.2300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.8641
    Cell Significance Index: 44.8900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.8452
    Cell Significance Index: 54.5300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.8259
    Cell Significance Index: 22.4800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.7980
    Cell Significance Index: 22.3000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.7831
    Cell Significance Index: 96.2900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7688
    Cell Significance Index: 125.0400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.7648
    Cell Significance Index: 22.0400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.7311
    Cell Significance Index: 131.7900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.7240
    Cell Significance Index: 395.3700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.6616
    Cell Significance Index: 18.8800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.5270
    Cell Significance Index: 14.1200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5248
    Cell Significance Index: 11.3700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.5239
    Cell Significance Index: 33.0200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.5102
    Cell Significance Index: 70.0700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.4906
    Cell Significance Index: 6.0900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.4436
    Cell Significance Index: 11.8500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4366
    Cell Significance Index: 394.2400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.3902
    Cell Significance Index: 13.5600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3819
    Cell Significance Index: 37.7800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3400
    Cell Significance Index: 150.3100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3137
    Cell Significance Index: 19.2800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.2957
    Cell Significance Index: 7.6000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.2306
    Cell Significance Index: 12.9400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.1711
    Cell Significance Index: 12.7500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1587
    Cell Significance Index: 5.5800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1506
    Cell Significance Index: 7.0800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1499
    Cell Significance Index: 19.3700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1323
    Cell Significance Index: 249.1600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1128
    Cell Significance Index: 21.4600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0978
    Cell Significance Index: 44.3800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0865
    Cell Significance Index: 159.4600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0770
    Cell Significance Index: 9.8700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0740
    Cell Significance Index: 113.9200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0632
    Cell Significance Index: 40.1200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0278
    Cell Significance Index: 37.7400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0253
    Cell Significance Index: 4.3200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0314
    Cell Significance Index: -23.0400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0408
    Cell Significance Index: -30.2200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0466
    Cell Significance Index: -6.7800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0629
    Cell Significance Index: -47.6400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0707
    Cell Significance Index: -8.3400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0725
    Cell Significance Index: -5.1300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0781
    Cell Significance Index: -3.6400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0859
    Cell Significance Index: -48.4500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0928
    Cell Significance Index: -2.4400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0940
    Cell Significance Index: -58.7100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.1149
    Cell Significance Index: -2.4600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1297
    Cell Significance Index: -13.2500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1511
    Cell Significance Index: -2.5900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1575
    Cell Significance Index: -45.3200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1673
    Cell Significance Index: -19.5000
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2425
    Cell Significance Index: -3.5800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2438
    Cell Significance Index: -25.3900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2627
    Cell Significance Index: -55.3300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3223
    Cell Significance Index: -36.9200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.3232
    Cell Significance Index: -7.7500
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.3587
    Cell Significance Index: -2.7700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3717
    Cell Significance Index: -6.2200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3803
    Cell Significance Index: -7.8900
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.4023
    Cell Significance Index: -3.7100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.4556
    Cell Significance Index: -13.0600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.4731
    Cell Significance Index: -10.3600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5496
    Cell Significance Index: -43.5300
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.5760
    Cell Significance Index: -14.0600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.5889
    Cell Significance Index: -7.0200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.7403
    Cell Significance Index: -18.5100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.7975
    Cell Significance Index: -16.9900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.8372
    Cell Significance Index: -16.3400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.8449
    Cell Significance Index: -17.6900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.8539
    Cell Significance Index: -52.3500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.9142
    Cell Significance Index: -29.2800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.9181
    Cell Significance Index: -29.2400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.9600
    Cell Significance Index: -31.4300
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.9687
    Cell Significance Index: -20.5600
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -1.0463
    Cell Significance Index: -26.7300
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -1.0794
    Cell Significance Index: -13.4600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -1.0882
    Cell Significance Index: -31.9600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** AKAP8L is a member of the A-kinase anchor protein (AKAP) family, which plays a crucial role in regulating protein kinase A (PKA) activity. AKAP8L is specifically implicated in the regulation of PKA activity, particularly in the context of cell cycle progression and gene expression. Its expression is highly restricted to specific cell types, including GABAergic cortical interneurons, astrocytes, and dopaminergic neurons. **Pathways and Functions:** AKAP8L is involved in various cellular pathways, including: 1. **Cell cycle regulation**: AKAP8L regulates the G2/M phase transition by modulating PKA activity, which in turn affects the expression of genes involved in cell cycle progression. 2. **Gene expression**: AKAP8L regulates gene expression by binding to transcription factors and influencing the activity of RNA polymerase II. 3. **Chromatin dynamics**: AKAP8L interacts with chromatin-modifying complexes, such as the WDR5-containing complex, to regulate histone modifications and chromatin structure. 4. **RNA processing**: AKAP8L regulates mRNA export from the nucleus, which is essential for gene expression and cellular function. **Clinical Significance:** The dysregulation of AKAP8L has been implicated in various human diseases, including: 1. **Neurological disorders**: AKAP8L expression is altered in neurodegenerative diseases, such as Alzheimer's and Parkinson's disease, suggesting its role in regulating neuronal function and survival. 2. **Cancer**: AKAP8L is involved in the regulation of cell cycle progression and gene expression, which can contribute to tumorigenesis and cancer progression. 3. **Neurodevelopmental disorders**: AKAP8L expression is altered in neurodevelopmental disorders, such as autism and schizophrenia, suggesting its role in regulating neuronal development and function. In conclusion, AKAP8L plays a critical role in regulating cellular processes, including cell cycle progression, gene expression, and chromatin dynamics. Its dysregulation has been implicated in various human diseases, highlighting the importance of further research into the mechanisms underlying AKAP8L function and its potential therapeutic applications. **Recommendations:** 1. Further investigation into the mechanisms underlying AKAP8L function and its regulation of cellular processes. 2. Elucidation of the molecular mechanisms underlying AKAP8L's involvement in human diseases. 3. Development of therapeutic strategies targeting AKAP8L to treat neurological and cancer disorders. By exploring the complex functions of AKAP8L, we can gain a deeper understanding of its role in maintaining cellular homeostasis and developing novel therapeutic strategies for human diseases.

Genular Protein ID: 976582219

Symbol: AKP8L_HUMAN

Name: A-kinase anchor protein 8-like

UniProtKB Accession Codes:

Q9ULX6 B4DJ74 B5BU90 O94792 Q96J58 Q9NRQ0 Q9UGM0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 13 Ensembl 2 ExpressionAtlas 1 GO 22 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SIGNOR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10697960

Title: cDNA cloning of a novel human gene NAKAP95, neighbor of A-kinase anchoring protein 95 (AKAP95) on chromosome 19p13.11-p13.12 region.

PubMed ID: 10697960

DOI: 10.1007/s100380070040

PubMed ID: 10761695

Title: Identification, cloning and characterization of a novel nuclear protein, HA95, homologous to A-kinase anchoring protein 95.

PubMed ID: 10761695

DOI: 10.1016/s0248-4900(00)88761-4

PubMed ID: 10748171

Title: A novel shuttle protein binds to RNA helicase A and activates the retroviral constitutive transport element.

PubMed ID: 10748171

DOI: 10.1074/jbc.m909887199

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 19054851

Title: Human protein factory for converting the transcriptome into an in vitro-expressed proteome.

PubMed ID: 19054851

DOI: 10.1038/nmeth.1273

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9853615

Title: Selection system for genes encoding nuclear-targeted proteins.

PubMed ID: 9853615

DOI: 10.1038/4315

PubMed ID: 11034899

Title: HA95 is a protein of the chromatin and nuclear matrix regulating nuclear envelope dynamics.

PubMed ID: 11034899

DOI: 10.1242/jcs.113.21.3703

PubMed ID: 11402034

Title: Mapping the functional domains of HAP95, a protein that binds RNA helicase A and activates the constitutive transport element of type D retroviruses.

PubMed ID: 11402034

DOI: 10.1074/jbc.m102809200

PubMed ID: 11160753

Title: EBNA-LP associates with cellular proteins including DNA-PK and HA95.

PubMed ID: 11160753

DOI: 10.1128/jvi.75.5.2475-2481.2001

PubMed ID: 11884601

Title: Protein kinase A associates with HA95 and affects transcriptional coactivation by Epstein-Barr virus nuclear proteins.

PubMed ID: 11884601

DOI: 10.1128/mcb.22.7.2136-2146.2002

PubMed ID: 12538639

Title: HA95 and LAP2 beta mediate a novel chromatin-nuclear envelope interaction implicated in initiation of DNA replication.

PubMed ID: 12538639

DOI: 10.1083/jcb.200210026

PubMed ID: 12950172

Title: In vitro modulation of the interaction between HA95 and LAP2beta by cAMP signaling.

PubMed ID: 12950172

DOI: 10.1021/bi0350699

PubMed ID: 16391387

Title: Interaction of the nuclear matrix protein NAKAP with HypA and huntingtin: implications for nuclear toxicity in Huntington's disease pathogenesis.

PubMed ID: 16391387

DOI: 10.1385/nmm:7:4:297

PubMed ID: 16980585

Title: A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity.

PubMed ID: 16980585

DOI: 10.1101/gad.1455006

PubMed ID: 17594903

Title: Involvement of the catalytic subunit of protein kinase A and of HA95 in pre-mRNA splicing.

PubMed ID: 17594903

DOI: 10.1016/j.yexcr.2007.05.014

PubMed ID: 18313049

Title: A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95.

PubMed ID: 18313049

DOI: 10.1016/j.yexcr.2008.01.013

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 25034436

Title: The role of A-kinase anchoring protein 95-like protein in annealing of tRNALys3 to HIV-1 RNA.

PubMed ID: 25034436

DOI: 10.1186/1742-4690-11-58

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 646
  • Mass: 71640
  • Checksum: CBC265BF25996BA2
  • Sequence:
    • MSYTGFVQGS ETTLQSTYSD TSAQPTCDYG YGTWNSGTNR GYEGYGYGYG YGQDNTTNYG 
YGMATSHSWE MPSSDTNANT SASGSASADS VLSRINQRLD MVPHLETDMM QGGVYGSGGE 
RYDSYESCDS RAVLSERDLY RSGYDYSELD PEMEMAYEGQ YDAYRDQFRM RGNDTFGPRA 
QGWARDARSG RPMASGYGRM WEDPMGARGQ CMSGASRLPS LFSQNIIPEY GMFQGMRGGG 
AFPGGSRFGF GFGNGMKQMR RTWKTWTTAD FRTKKKKRKQ GGSPDEPDSK ATRTDCSDNS 
DSDNDEGTEG EATEGLEGTE AVEKGSRVDG EDEEGKEDGR EEGKEDPEKG ALTTQDENGQ 
TKRKLQAGKK SQDKQKKRQR DRMVERIQFV CSLCKYRTFY EDEMASHLDS KFHKEHFKYV 
GTKLPKQTAD FLQEYVTNKT KKTEELRKTV EDLDGLIQQI YRDQDLTQEI AMEHFVKKVE 
AAHCAACDLF IPMQFGIIQK HLKTMDHNRN RRLMMEQSKK SSLMVARSIL NNKLISKKLE 
RYLKGENPFT DSPEEEKEQE EAEGGALDEG AQGEAAGISE GAEGVPAQPP VPPEPAPGAV 
SPPPPPPPEE EEEGAVPLLG GALQRQIRGI PGLDVEDDEE GGGGAP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.