Details for: GLS2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 52.2678
Cell Significance Index: -8.1300 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 32.0529
Cell Significance Index: -8.1300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 6.6020
Cell Significance Index: -8.1400 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 2.3266
Cell Significance Index: 34.3400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.2140
Cell Significance Index: 243.5300 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.8951
Cell Significance Index: 19.6000 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 0.8277
Cell Significance Index: 6.3800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.7752
Cell Significance Index: 34.2900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.7740
Cell Significance Index: 29.3100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.6023
Cell Significance Index: 114.6200 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.5606
Cell Significance Index: 11.9400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.5360
Cell Significance Index: 33.7800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.4876
Cell Significance Index: 96.7600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4613
Cell Significance Index: 45.6400 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: 0.4412
Cell Significance Index: 5.8900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.4411
Cell Significance Index: 7.5600 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.4258
Cell Significance Index: 5.8100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.3438
Cell Significance Index: 123.3300 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.3278
Cell Significance Index: 19.6800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.2609
Cell Significance Index: 13.7000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2393
Cell Significance Index: 216.0700 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.2249
Cell Significance Index: 36.5700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.2151
Cell Significance Index: 5.5300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.1995
Cell Significance Index: 12.2700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.1797
Cell Significance Index: 9.3400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.1639
Cell Significance Index: 4.5800 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.1434
Cell Significance Index: 3.4400 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: 0.1334
Cell Significance Index: 1.6800 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.1216
Cell Significance Index: 2.6000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1092
Cell Significance Index: 18.6500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0968
Cell Significance Index: 6.7000 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.0911
Cell Significance Index: 1.1300 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0802
Cell Significance Index: 35.4800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.0584
Cell Significance Index: 1.5900 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.0419
Cell Significance Index: 0.5000 - Cell Name: hepatoblast (CL0005026)
Fold Change: 0.0404
Cell Significance Index: 0.6800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0213
Cell Significance Index: 3.8400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0199
Cell Significance Index: 2.3200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0162
Cell Significance Index: 0.3500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0128
Cell Significance Index: 0.4500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0104
Cell Significance Index: 0.3000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0086
Cell Significance Index: 0.3900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0061
Cell Significance Index: 3.3100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0048
Cell Significance Index: 0.5900 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.0002
Cell Significance Index: 0.0100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0045
Cell Significance Index: -8.4900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0048
Cell Significance Index: -0.1200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0068
Cell Significance Index: -4.9900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0069
Cell Significance Index: -5.2100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0074
Cell Significance Index: -5.5100 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: -0.0082
Cell Significance Index: -0.0900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0090
Cell Significance Index: -5.0500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0104
Cell Significance Index: -6.6100 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0125
Cell Significance Index: -0.5400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0130
Cell Significance Index: -8.0900 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0136
Cell Significance Index: -0.9600 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.0142
Cell Significance Index: -0.2400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0152
Cell Significance Index: -6.8900 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0169
Cell Significance Index: -0.3500 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.0177
Cell Significance Index: -0.1200 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0210
Cell Significance Index: -0.6700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0213
Cell Significance Index: -6.1200 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0236
Cell Significance Index: -0.5000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0262
Cell Significance Index: -0.8400 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.0264
Cell Significance Index: -0.5300 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0314
Cell Significance Index: -0.6200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0357
Cell Significance Index: -4.0900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0366
Cell Significance Index: -7.7000 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.0426
Cell Significance Index: -0.9200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0442
Cell Significance Index: -6.4200 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0478
Cell Significance Index: -6.1800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0482
Cell Significance Index: -4.9200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0483
Cell Significance Index: -6.6300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0487
Cell Significance Index: -2.2700 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0510
Cell Significance Index: -1.6700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0513
Cell Significance Index: -6.0500 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0531
Cell Significance Index: -0.7600 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.0547
Cell Significance Index: -0.5200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0759
Cell Significance Index: -6.0100 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0764
Cell Significance Index: -1.9100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0772
Cell Significance Index: -5.9300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0776
Cell Significance Index: -5.7800 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0815
Cell Significance Index: -1.5900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0827
Cell Significance Index: -8.6100 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: -0.0828
Cell Significance Index: -0.9900 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1013
Cell Significance Index: -3.5500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1040
Cell Significance Index: -6.9900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1103
Cell Significance Index: -6.1900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1105
Cell Significance Index: -7.1300 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: -0.1110
Cell Significance Index: -0.9600 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.1136
Cell Significance Index: -2.3700 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.1147
Cell Significance Index: -1.2500 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.1267
Cell Significance Index: -1.5800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1294
Cell Significance Index: -6.0800 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.1295
Cell Significance Index: -3.1400 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.1539
Cell Significance Index: -5.6500 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.1600
Cell Significance Index: -2.0200 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.1619
Cell Significance Index: -2.4400 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: -0.1642
Cell Significance Index: -1.9900 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.1693
Cell Significance Index: -2.5000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3831391070
Symbol: GLSL_HUMAN
Name: Glutaminase liver isoform, mitochondrial
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10620514
Title: Molecular cloning, sequencing and expression studies of the human breast cancer cell glutaminase.
PubMed ID: 10620514
DOI: 10.1042/bj3450365
PubMed ID: 12444921
Title: Genomic organization and transcriptional analysis of the human l-glutaminase gene.
PubMed ID: 12444921
DOI: 10.1042/bj20021445
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 11163757
Title: The C-terminus of human glutaminase L mediates association with PDZ domain-containing proteins.
PubMed ID: 11163757
PubMed ID: 20378837
Title: Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function.
PubMed ID: 20378837
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 28526749
Title: The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
PubMed ID: 28526749
Sequence Information:
- Length: 602
- Mass: 66323
- Checksum: 6D0E1EFF01BC3843
- Sequence:
MRSMKALQKA LSRAGSHCGR GGWGHPSRSP LLGGGVRHHL SEAAAQGRET PHSHQPQHQD HDSSESGMLS RLGDLLFYTI AEGQERIPIH KFTTALKATG LQTSDPRLRD CMSEMHRVVQ ESSSGGLLDR DLFRKCVSSN IVLLTQAFRK KFVIPDFEEF TGHVDRIFED VKELTGGKVA AYIPQLAKSN PDLWGVSLCT VDGQRHSVGH TKIPFCLQSC VKPLTYAISI STLGTDYVHK FVGKEPSGLR YNKLSLNEEG IPHNPMVNAG AIVVSSLIKM DCNKAEKFDF VLQYLNKMAG NEYMGFSNAT FQSEKETGDR NYAIGYYLKE KKCFPKGVDM MAALDLYFQL CSVEVTCESG SVMAATLANG GICPITGESV LSAEAVRNTL SLMHSCGMYD FSGQFAFHVG LPAKSAVSGA ILLVVPNVMG MMCLSPPLDK LGNSHRGTSF CQKLVSLFNF HNYDNLRHCA RKLDPRREGA EIRNKTVVNL LFAAYSGDVS ALRRFALSAM DMEQKDYDSR TALHVAAAEG HIEVVKFLIE ACKVNPFAKD RWGNIPLDDA VQFNHLEVVK LLQDYQDSYT LSETQAEAAA EALSKENLES MV
Genular Protein ID: 3159622555
Symbol: A0A087X004_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11181995
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
Sequence Information:
- Length: 337
- Mass: 37094
- Checksum: 4D8AD7C71F5D1372
- Sequence:
MVNAGAIVVS SLIKMDCNKA EKFDFVLQYL NKMAGNEYMG FSNATFQSEK ETGDRNYAIG YYLKEKKCFP KGVDMMAALD LYFQLCSVEV TCESGSVMAA TLANGGICPI TGESVLSAEA VRNTLSLMHS CGMYDFSGQF AFHVGLPAKS AVSGAILLVV PNVMGMMCLS PPLDKLGNSH RGTSFCQKLV SLFNFHNYDN LRHCARKLDP RREGAEIRNK TVVNLLFAAY SGDVSALRRF ALSAMDMEQK DYDSRTALHV AAAEGHIEVV KFLIEACKVN PFAKDRWGNI PLDDAVQFNH LEVVKLLQDY QDSYTLSETQ AEAAAEALSK ENLESMV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.