Details for: UTP20

Gene ID: 27340

Symbol: UTP20

Ensembl ID: ENSG00000120800

Description: UTP20 small subunit processome component

Associated with

  • Major pathway of rrna processing in the nucleolus and cytosol
    (R-HSA-6791226)
  • Metabolism of rna
    (R-HSA-8953854)
  • Rrna modification in the nucleus and cytosol
    (R-HSA-6790901)
  • Rrna processing in the nucleus and cytosol
    (R-HSA-8868773)
  • 90s preribosome
    (GO:0030686)
  • Cytoplasm
    (GO:0005737)
  • Endonucleolytic cleavage in 5'-ets of tricistronic rrna transcript (ssu-rrna, 5.8s rrna, lsu-rrna)
    (GO:0000480)
  • Endonucleolytic cleavage in its1 to separate ssu-rrna from 5.8s rrna and lsu-rrna from tricistronic rrna transcript (ssu-rrna, 5.8s rrna, lsu-rrna)
    (GO:0000447)
  • Endonucleolytic cleavage to generate mature 5'-end of ssu-rrna from (ssu-rrna, 5.8s rrna, lsu-rrna)
    (GO:0000472)
  • Negative regulation of cell population proliferation
    (GO:0008285)
  • Nucleolus
    (GO:0005730)
  • Nucleoplasm
    (GO:0005654)
  • Plasma membrane
    (GO:0005886)
  • Preribosome, small subunit precursor
    (GO:0030688)
  • Protein binding
    (GO:0005515)
  • Ribosomal small subunit biogenesis
    (GO:0042274)
  • Rna binding
    (GO:0003723)
  • Rrna processing
    (GO:0006364)
  • Small-subunit processome
    (GO:0032040)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 139.5093
    Cell Significance Index: -21.7000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 83.6213
    Cell Significance Index: -21.2100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 50.0082
    Cell Significance Index: -23.6100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 48.3438
    Cell Significance Index: -19.6400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 20.5815
    Cell Significance Index: -19.6500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 18.2042
    Cell Significance Index: -22.4500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.3282
    Cell Significance Index: -22.3100
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 5.8051
    Cell Significance Index: -17.8300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.7475
    Cell Significance Index: -22.6800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.3462
    Cell Significance Index: 267.1600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0762
    Cell Significance Index: 971.7500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8737
    Cell Significance Index: 95.0300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8608
    Cell Significance Index: 140.0000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.7447
    Cell Significance Index: 44.7100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.6579
    Cell Significance Index: 12.8400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6451
    Cell Significance Index: 129.4100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.6008
    Cell Significance Index: 16.7900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4586
    Cell Significance Index: 317.1700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.4530
    Cell Significance Index: 25.4200
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.4439
    Cell Significance Index: 6.6900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.4209
    Cell Significance Index: 10.8200
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.3963
    Cell Significance Index: 8.4700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3961
    Cell Significance Index: 27.3900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3584
    Cell Significance Index: 64.6200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.3410
    Cell Significance Index: 15.9000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3398
    Cell Significance Index: 121.8800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.3040
    Cell Significance Index: 8.1500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2848
    Cell Significance Index: 125.9200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2833
    Cell Significance Index: 13.3100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.2825
    Cell Significance Index: 21.6800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2392
    Cell Significance Index: 5.9800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2217
    Cell Significance Index: 27.2700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.2171
    Cell Significance Index: 11.3100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2161
    Cell Significance Index: 21.3800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2029
    Cell Significance Index: 5.8500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1854
    Cell Significance Index: 13.1100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.1845
    Cell Significance Index: 4.0400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1439
    Cell Significance Index: 19.7600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1320
    Cell Significance Index: 72.1000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1111
    Cell Significance Index: 3.0300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1013
    Cell Significance Index: 4.5900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0711
    Cell Significance Index: 1.5400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0647
    Cell Significance Index: 3.3600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0585
    Cell Significance Index: 3.9400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0536
    Cell Significance Index: 10.2000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0517
    Cell Significance Index: 3.1800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0386
    Cell Significance Index: 72.7700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0346
    Cell Significance Index: 53.2100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0345
    Cell Significance Index: 63.5500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0158
    Cell Significance Index: 0.7000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0128
    Cell Significance Index: 1.6500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0111
    Cell Significance Index: 0.1900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0097
    Cell Significance Index: 6.1800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0070
    Cell Significance Index: 0.8200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0061
    Cell Significance Index: 8.3000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0030
    Cell Significance Index: 0.0800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0020
    Cell Significance Index: 0.0700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0011
    Cell Significance Index: 0.4900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0046
    Cell Significance Index: -0.7900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0094
    Cell Significance Index: -1.2100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0157
    Cell Significance Index: -0.9900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0180
    Cell Significance Index: -13.1800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0209
    Cell Significance Index: -15.8500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0261
    Cell Significance Index: -3.7900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0283
    Cell Significance Index: -1.0700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0299
    Cell Significance Index: -22.1600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0419
    Cell Significance Index: -26.1500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0427
    Cell Significance Index: -24.0900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0643
    Cell Significance Index: -6.5700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0672
    Cell Significance Index: -19.3400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0685
    Cell Significance Index: -4.2000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0715
    Cell Significance Index: -4.6100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0831
    Cell Significance Index: -1.7700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0985
    Cell Significance Index: -11.4800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0987
    Cell Significance Index: -11.3100
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.1163
    Cell Significance Index: -1.6700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1230
    Cell Significance Index: -25.9200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1349
    Cell Significance Index: -1.8400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1812
    Cell Significance Index: -18.8700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2018
    Cell Significance Index: -15.0400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2042
    Cell Significance Index: -6.5400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2315
    Cell Significance Index: -6.6100
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.2414
    Cell Significance Index: -3.4600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2628
    Cell Significance Index: -20.8100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3037
    Cell Significance Index: -7.9900
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.3116
    Cell Significance Index: -7.2000
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.3244
    Cell Significance Index: -1.9600
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.3379
    Cell Significance Index: -4.8600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.3503
    Cell Significance Index: -8.4000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3517
    Cell Significance Index: -12.2200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3565
    Cell Significance Index: -18.7200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3667
    Cell Significance Index: -18.5300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.3900
    Cell Significance Index: -6.5700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3932
    Cell Significance Index: -11.2700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4098
    Cell Significance Index: -6.0500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4149
    Cell Significance Index: -13.2200
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.4390
    Cell Significance Index: -6.4800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4445
    Cell Significance Index: -11.8900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4502
    Cell Significance Index: -14.7400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.4517
    Cell Significance Index: -7.5600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** UTP20 is a small subunit processome component that is specifically expressed in eukaryotic cells. The gene is characterized by its involvement in several key cellular processes, including: * Ribosomal biogenesis: UTP20 is a critical component of the small subunit processome, which is responsible for the processing and maturation of rRNA molecules. * RNA metabolism: UTP20 is involved in the metabolism of rRNA, including the endonucleolytic cleavage of rRNA transcripts. * Cell proliferation: UTP20 has been shown to regulate cell population proliferation, suggesting its involvement in cell growth and division. * Immune responses: UTP20 is expressed in immune cells, such as macrophages and dendritic cells, and has been implicated in the regulation of immune responses. **Pathways and Functions** UTP20 is involved in several key pathways, including: * Endonucleolytic cleavage in 5'-ets of tricistronic rRNA transcript (ssu-rrna, 5.8s rRNA, lsu-rrna) * Endonucleolytic cleavage in its1 to separate ssu-rrna from 5.8s rRNA and lsu-rrna from tricistronic rRNA transcript (ssu-rrna, 5.8s rRNA, lsu-rrna) * Endonucleolytic cleavage to generate mature 5'-end of ssu-rrna from (ssu-rrna, 5.8s rRNA, lsu-rrna) * Major pathway of rRNA processing in the nucleolus and cytosol * Metabolism of rRNA * Negative regulation of cell population proliferation * Nucleolus * Nucleoplasm * Plasma membrane * Preribosome * Small subunit precursor * Protein binding * Ribosomal small subunit biogenesis * RNA binding * RNA modification in the nucleus and cytosol * RNA processing in the nucleus and cytosol * Small-subunit processome **Clinical Significance** UTP20 has been implicated in various diseases and disorders, including: * Neurodegenerative diseases: UTP20 has been shown to be involved in the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. * Cancer: UTP20 has been implicated in the regulation of cell proliferation and tumorigenesis in various types of cancer. * Immune disorders: UTP20 has been shown to play a critical role in the regulation of immune responses and the development of autoimmune diseases. In conclusion, UTP20 is a critical component of the small subunit processome, involved in the biogenesis of ribosomal subunits and the regulation of various cellular processes, including RNA metabolism, cell proliferation, and immune responses. Further research is needed to fully understand the role of UTP20 in disease and to explore its potential as a therapeutic target.

Genular Protein ID: 3530361423

Symbol: UTP20_HUMAN

Name: Small subunit processome component 20 homolog

UniProtKB Accession Codes:

O75691 Q9H3H4

Database IDs:

AGR 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 CarbonylDB 1 ChiTaRS 1 ComplexPortal 1 DNASU 1 DisGeNET 1 EMBL 4 EMDB 3 Ensembl 1 GO 14 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9673349

Title: Differential gene expression in mammary carcinoma cell lines: identification of DRIM, a new gene down-regulated in metastasis.

PubMed ID: 9673349

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 11790298

Title: Directed proteomic analysis of the human nucleolus.

PubMed ID: 11790298

DOI: 10.1016/s0960-9822(01)00650-9

PubMed ID: 12429849

Title: Functional proteomic analysis of human nucleolus.

PubMed ID: 12429849

DOI: 10.1091/mbc.e02-05-0271

PubMed ID: 16053918

Title: KIAA0649, a 1A6/DRIM-interacting protein with the oncogenic potential.

PubMed ID: 16053918

DOI: 10.1016/j.bbrc.2005.06.179

PubMed ID: 16458307

Title: Mapping nucleolar localization sequences of 1A6/DRIM.

PubMed ID: 16458307

DOI: 10.1016/j.febslet.2006.01.064

PubMed ID: 17498821

Title: Human 1A6/DRIM, the homolog of yeast Utp20, functions in the 18S rRNA processing.

PubMed ID: 17498821

DOI: 10.1016/j.bbamcr.2007.04.002

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 34516797

Title: Nucleolar maturation of the human small subunit processome.

PubMed ID: 34516797

DOI: 10.1126/science.abj5338

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 2785
  • Mass: 318385
  • Checksum: 0CE63611C8440E0D
  • Sequence:
    • MKTKPVSHKT ENTYRFLTFA ERLGNVNIDI IHRIDRTASY EEEVETYFFE GLLKWRELNL 
TEHFGKFYKE VIDKCQSFNQ LVYHQNEIVQ SLKTHLQVKN SFAYQPLLDL VVQLARDLQM 
DFYPHFPEFF LTITSILETQ DTELLEWAFT SLSYLYKYLW RLMVKDMSSI YSMYSTLLAH 
KKLHIRNFAA ESFTFLMRKV SDKNALFNLM FLDLDKHPEK VEGVGQLLFE MCKGVRNMFH 
SCTGQAVKLI LRKLGPVTET ETQLPWMLIG ETLKNMVKST VSYISKEHFG TFFECLQESL 
LDLHTKVTKT NCCESSEQIK RLLETYLILV KHGSGTKIPT PADVCKVLSQ TLQVASLSTS 
CWETLLDVIS ALILGENVSL PETLIKETIE KIFESRFEKR LIFSFSEVMF AMKQFEQLFL 
PSFLSYIVNC FLIDDAVVKD EALAILAKLI LNKAAPPTAG SMAIEKYPLV FSPQMVGFYI 
KQKKTRSKGR NEQFPVLDHL LSIIKLPPNK DTTYLSQSWA ALVVLPHIRP LEKEKVIPLV 
TGFIEALFMT VDKGSFGKGN LFVLCQAVNT LLSLEESSEL LHLVPVERVK NLVLTFPLEP 
SVLLLTDLYY QRLALCGCKG PLSQEALMEL FPKLQANIST GVSKIRLLTI RILNHFDVQL 
PESMEDDGLS ERQSVFAILR QAELVPATVN DYREKLLHLR KLRHDVVQTA VPDGPLQEVP 
LRYLLGMLYI NFSALWDPVI ELISSHAHEM ENKQFWKVYY EHLEKAATHA EKELQNDMTD 
EKSVGDESWE QTQEGDVGAL YHEQLALKTD CQERLDHTNF RFLLWRALTK FPERVEPRSR 
ELSPLFLRFI NNEYYPADLQ VAPTQDLRRK GKGMVAEEIE EEPAAGDDEE LEEEAVPQDE 
SSQKKKTRRA AAKQLIAHLQ VFSKFSNPRA LYLESKLYEL YLQLLLHQDQ MVQKITLDCI 
MTYKHPHVLP YRENLQRLLE DRSFKEEIVH FSISEDNAVV KTAHRADLFP ILMRILYGRM 
KNKTGSKTQG KSASGTRMAI VLRFLAGTQP EEIQIFLDLL FEPVRHFKNG ECHSAVIQAV 
EDLDLSKVLP LGRQHGILNS LEIVLKNISH LISAYLPKIL QILLCMTATV SHILDQREKI 
QLRFINPLKN LRRLGIKMVT DIFLDWESYQ FRTEEIDAVF HGAVWPQISR LGSESQYSPT 
PLLKLISIWS RNARYFPLLA KQKPGHPECD ILTNVFAILS AKNLSDATAS IVMDIVDDLL 
NLPDFEPTET VLNLLVTGCV YPGIAENIGE SITIGGRLIL PHVPAILQYL SKTTISAEKV 
KKKKNRAQVS KELGILSKIS KFMKDKEQSS VLITLLLPFL HRGNIAEDTE VDILVTVQNL 
LKHCVDPTSF LKPIAKLFSV IKNKLSRKLL CTVFETLSDF ESGLKYITDV VKLNAFDQRH 
LDDINFDVRF ETFQTITSYI KEMQIVDVNY LIPVMHNCFY NLELGDMSLS DNASMCLMSI 
IKKLAALNVT EKDYREIIHR SLLEKLRKGL KSQTESIQQD YTTILSCLIQ TFPNQLEFKD 
LVQLTHYHDP EMDFFENMKH IQIHRRARAL KKLAKQLMEG KVVLSSKSLQ NYIMPYAMTP 
IFDEKMLKHE NITTAATEII GAICKHLSWS AYMYYLKHFI HVLQTGQINQ KLGVSLLVIV 
LEAFHFDHKT LEEQMGKIEN EENAIEAIEL PEPEAMELER VDEEEKEYTC KSLSDNGQPG 
TPDPADSGGT SAKESECITK PVSFLPQNKE EIERTIKNIQ GTITGDILPR LHKCLASTTK 
REEEHKLVKS KVVNDEEVVR VPLAFAMVKL MQSLPQEVME ANLPSILLKV CALLKNRAQE 
IRDIARSTLA KIIEDLGVHF LLYVLKELQT TLVRGYQVHV LTFTVHMLLQ GLTNKLQVGD 
LDSCLDIMIE IFNHELFGAV AEEKEVKQIL SKVMEARRSK SYDSYEILGK FVGKDQVTKL 
ILPLKEILQN TTSLKLARKV HETLRRITVG LIVNQEMTAE SILLLSYGLI SENLPLLTEK 
EKNPVAPAPD PRLPPQSCLL LPPTPVRGGQ KAVVSRKTNM HIFIESGLRL LHLSLKTSKI 
KSSGECVLEM LDPFVSLLID CLGSMDVKVI TGALQCLIWV LRFPLPSIET KAEQLTKHLF 
LLLKDYAKLG AARGQNFHLV VNCFKCVTIL VKKVKSYQIT EKQLQVLLAY AEEDIYDTSR 
QATAFGLLKA ILSRKLLVPE IDEVMRKVSK LAVSAQSEPA RVQCRQVFLK YILDYPLGDK 
LRPNLEFMLA QLNYEHETGR ESTLEMIAYL FDTFPQGLLH ENCGMFFIPL CLMTINDDSA 
TCKKMASMTI KSLLGKISLE KKDWLFDMVT TWFGAKKRLN RQLAALICGL FVESEGVDFE 
KRLGTVLPVI EKEIDPENFK DIMEETEEKA ADRLLFSFLT LITKLIKECN IIQFTKPAET 
LSKIWSHVHS HLRHPHNWVW LTAAQIFGLL FASCQPEELI QKWNTKKTKK HLPEPVAIKF 
LASDLDQKMK SISLASCHQL HSKFLDQSLG EQVVKNLLFA AKVLYLLELY CEDKQSKIKE 
DLEEQEALED GVACADEKAE SDGEEKEEVK EELGRPATLL WLIQKLSRIA KLEAAYSPRN 
PLKRTCIFKF LGAVAMDLGI DKVKPYLPMI IAPLFRELNS TYSEQDPLLK NLSQEIIELL 
KKLVGLESFS LAFASVQKQA NEKRALRKKR KALEFVTNPD IAAKKKMKKH KNKSEAKKRK 
IEFLRPGYKA KRQKSHSLKD LAMVE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.