Details for: GLI2

Gene ID: 2736

Symbol: GLI2

Ensembl ID: ENSG00000074047

Description: GLI family zinc finger 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 33.8895
    Cell Significance Index: -16.0000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.5833
    Cell Significance Index: 144.9600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.8751
    Cell Significance Index: 17.0800
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.8030
    Cell Significance Index: 12.7400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.6933
    Cell Significance Index: 35.0400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.3763
    Cell Significance Index: 8.2400
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.3050
    Cell Significance Index: 4.3800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1888
    Cell Significance Index: 83.4900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1299
    Cell Significance Index: 16.6500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1042
    Cell Significance Index: 14.3100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0543
    Cell Significance Index: 33.9200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0363
    Cell Significance Index: 25.1000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0266
    Cell Significance Index: 12.0900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0261
    Cell Significance Index: 9.3600
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.0188
    Cell Significance Index: 0.1600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0097
    Cell Significance Index: 18.2000
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 0.0043
    Cell Significance Index: 0.0600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.0038
    Cell Significance Index: 0.0800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0011
    Cell Significance Index: 1.7100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0029
    Cell Significance Index: -1.8200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0036
    Cell Significance Index: -2.6600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0063
    Cell Significance Index: -3.5600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0090
    Cell Significance Index: -16.5700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0120
    Cell Significance Index: -2.4000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0149
    Cell Significance Index: -20.2400
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0162
    Cell Significance Index: -0.2800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0168
    Cell Significance Index: -0.4700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0204
    Cell Significance Index: -14.9900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0228
    Cell Significance Index: -17.2500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0257
    Cell Significance Index: -0.4300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0265
    Cell Significance Index: -3.8500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0293
    Cell Significance Index: -6.1700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0301
    Cell Significance Index: -16.4400
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0321
    Cell Significance Index: -0.4600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0432
    Cell Significance Index: -8.5700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0440
    Cell Significance Index: -12.6600
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.0456
    Cell Significance Index: -0.9800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0590
    Cell Significance Index: -10.0800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0614
    Cell Significance Index: -11.0600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0635
    Cell Significance Index: -6.6100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0861
    Cell Significance Index: -5.2900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1071
    Cell Significance Index: -13.1700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1149
    Cell Significance Index: -13.1200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1171
    Cell Significance Index: -3.0100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1173
    Cell Significance Index: -15.1500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1212
    Cell Significance Index: -14.1300
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.1290
    Cell Significance Index: -0.8100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1380
    Cell Significance Index: -9.7600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1463
    Cell Significance Index: -14.9400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1510
    Cell Significance Index: -17.3100
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.1668
    Cell Significance Index: -0.9900
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: -0.1778
    Cell Significance Index: -1.9900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1787
    Cell Significance Index: -13.7200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2041
    Cell Significance Index: -15.2100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2182
    Cell Significance Index: -14.6700
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.2238
    Cell Significance Index: -5.4200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2281
    Cell Significance Index: -7.9300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2588
    Cell Significance Index: -13.4800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2626
    Cell Significance Index: -4.5000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2698
    Cell Significance Index: -12.6800
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -0.3109
    Cell Significance Index: -2.2600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3433
    Cell Significance Index: -9.8400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3461
    Cell Significance Index: -17.9800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3586
    Cell Significance Index: -15.8600
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.3722
    Cell Significance Index: -4.2600
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.3998
    Cell Significance Index: -5.1200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.4088
    Cell Significance Index: -19.0600
  • Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
    Fold Change: -0.4169
    Cell Significance Index: -3.7900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.4196
    Cell Significance Index: -15.8900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4235
    Cell Significance Index: -12.4800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.4236
    Cell Significance Index: -14.8400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4682
    Cell Significance Index: -15.3300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.4799
    Cell Significance Index: -11.5100
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.4812
    Cell Significance Index: -6.8500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4826
    Cell Significance Index: -15.3700
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: -0.4856
    Cell Significance Index: -3.0400
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.4875
    Cell Significance Index: -5.3000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.5079
    Cell Significance Index: -13.6100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.5238
    Cell Significance Index: -19.2300
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.5261
    Cell Significance Index: -13.1200
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: -0.5313
    Cell Significance Index: -6.1700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.5322
    Cell Significance Index: -15.6300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.5453
    Cell Significance Index: -15.5600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.5475
    Cell Significance Index: -19.2400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5556
    Cell Significance Index: -14.6100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.5589
    Cell Significance Index: -14.9500
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.5615
    Cell Significance Index: -17.7600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.5876
    Cell Significance Index: -15.6900
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: -0.6014
    Cell Significance Index: -5.9500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.6224
    Cell Significance Index: -13.2100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.6226
    Cell Significance Index: -15.5300
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.6368
    Cell Significance Index: -16.2300
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.6614
    Cell Significance Index: -16.5200
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.6617
    Cell Significance Index: -28.7700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.6667
    Cell Significance Index: -19.2100
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.6818
    Cell Significance Index: -14.7300
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.6842
    Cell Significance Index: -14.2800
  • Cell Name: stromal cell of endometrium (CL0002255)
    Fold Change: -0.7079
    Cell Significance Index: -10.0700
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.7089
    Cell Significance Index: -13.8600
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.7129
    Cell Significance Index: -10.0000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** GLI2 is a member of the GLI family of transcription factors, which are zinc finger proteins that bind to specific DNA sequences to regulate gene expression. The GLI2 protein is characterized by its ability to bind to the Hedgehog-related gene (HH) promoter, promoting the transcription of target genes involved in Hedgehog signaling. GLI2 is also known for its role in negative regulation of transcription, as it can repress the expression of certain genes by binding to specific DNA sequences. Furthermore, GLI2 is involved in the regulation of DNA replication and transcription, highlighting its central role in cell growth and proliferation. **Pathways and Functions** The GLI2 gene is involved in various signaling pathways, including: 1. **Hedgehog signaling pathway**: GLI2 is a key component of the Hedgehog signaling pathway, which plays a crucial role in embryonic development, tissue patterning, and cell growth. 2. **Axon guidance**: GLI2 regulates the expression of genes involved in axon guidance, which is essential for the proper formation of neural connections. 3. **Branching morphogenesis**: GLI2 is involved in the regulation of branching morphogenesis, which is a critical process in the development of epithelial tubes, such as the lung and gut. 4. **Skeletal system development**: GLI2 regulates the expression of genes involved in skeletal system development, including the formation of bone and cartilage. 5. **Cell growth and proliferation**: GLI2 is involved in the regulation of cell growth and proliferation, as it can promote or repress the expression of target genes involved in these processes. **Clinical Significance** Dysregulation of the GLI2 gene has been implicated in various diseases, including: 1. **Neurological disorders**: Mutations in the GLI2 gene have been associated with neurological disorders, such as spina bifida and holoprosencephaly. 2. **Cancer**: GLI2 is often overexpressed in various types of cancer, including lung, breast, and colon cancer, highlighting its potential role as a oncogene. 3. **Developmental abnormalities**: GLI2 is involved in the regulation of developmental processes, and dysregulation of the gene can lead to developmental abnormalities, such as limb abnormalities and heart defects. 4. **Regenerative medicine**: GLI2 may have potential applications in regenerative medicine, as it can be used to regulate the expression of genes involved in tissue repair and regeneration. In conclusion, the GLI2 gene plays a crucial role in various developmental processes, including branching morphogenesis, axon guidance, and skeletal system development. Its dysregulation has been implicated in various diseases, highlighting its potential as a therapeutic target for the treatment of neurological disorders, cancer, and developmental abnormalities.

Genular Protein ID: 2951492925

Symbol: GLI2_HUMAN

Name: N/A

UniProtKB Accession Codes:

P10070 O60252 O60253 O60254 O60255 Q15590 Q15591 Q4JHT4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEMBL 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 11 Ensembl 1 ExpressionAtlas 1 GO 52 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MIM 5 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 8 OrthoDB 1 PANTHER 2 PIR 3 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 5 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9557682

Title: Cloning of novel isoforms of the human Gli2 oncogene and their activities to enhance tax-dependent transcription of the human T-cell leukemia virus type 1 genome.

PubMed ID: 9557682

DOI: 10.1128/jvi.72.5.3958-3964.1998

PubMed ID: 15994174

Title: A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2.

PubMed ID: 15994174

DOI: 10.1093/hmg/ddi222

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 8350401

Title: A new regulatory element that augments the Tax-dependent enhancer of human T-cell leukemia virus type 1 and cloning of cDNAs encoding its binding proteins.

PubMed ID: 8350401

DOI: 10.1128/jvi.67.9.5375-5382.1993

PubMed ID: 2850480

Title: The GLI-Kruppel family of human genes.

PubMed ID: 2850480

DOI: 10.1128/mcb.8.8.3104-3113.1988

PubMed ID: 10806483

Title: Gli regulation by the opposing activities of fused and suppressor of fused.

PubMed ID: 10806483

DOI: 10.1038/35010610

PubMed ID: 14581620

Title: Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features.

PubMed ID: 14581620

DOI: 10.1073/pnas.2235734100

PubMed ID: 18455992

Title: Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling.

PubMed ID: 18455992

DOI: 10.1016/j.cell.2008.02.047

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19878745

Title: Identification of a novel serine/threonine kinase ULK3 as a positive regulator of Hedgehog pathway.

PubMed ID: 19878745

DOI: 10.1016/j.yexcr.2009.10.018

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23762415

Title: Gli2 acetylation at lysine 757 regulates hedgehog-dependent transcriptional output by preventing its promoter occupancy.

PubMed ID: 23762415

DOI: 10.1371/journal.pone.0065718

PubMed ID: 24311597

Title: Structural basis of SUFU-GLI interaction in human Hedgehog signalling regulation.

PubMed ID: 24311597

DOI: 10.1107/s0907444913028473

PubMed ID: 20685856

Title: Novel heterozygous nonsense GLI2 mutations in patients with hypopituitarism and ectopic posterior pituitary lobe without holoprosencephaly.

PubMed ID: 20685856

DOI: 10.1210/jc.2010-1050

PubMed ID: 26565916

Title: FOXC1 activates smoothened-independent Hedgehog signaling in basal-like breast cancer.

PubMed ID: 26565916

DOI: 10.1016/j.celrep.2015.09.063

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 17096318

Title: GLI2 mutations in four Brazilian patients: how wide is the phenotypic spectrum?

PubMed ID: 17096318

DOI: 10.1002/ajmg.a.31370

PubMed ID: 23408573

Title: Functional characterization of a heterozygous GLI2 missense mutation in patients with multiple pituitary hormone deficiency.

PubMed ID: 23408573

DOI: 10.1210/jc.2012-3224

PubMed ID: 27535533

Title: Analysis of protein-coding genetic variation in 60,706 humans.

PubMed ID: 27535533

DOI: 10.1038/nature19057

PubMed ID: 28973407

Title: GLI1 inactivation is associated with developmental phenotypes overlapping with Ellis-van Creveld syndrome.

PubMed ID: 28973407

DOI: 10.1093/hmg/ddx335

Sequence Information:

  • Length: 1586
  • Mass: 167783
  • Checksum: 86556112E13DE106
  • Sequence:
    • METSASATAS EKQEAKSGIL EAAGFPDPGK KASPLVVAAA AAAAVAAQGV PQHLLPPFHA 
PLPIDMRHQE GRYHYEPHSV HGVHGPPALS GSPVISDISL IRLSPHPAGP GESPFNAPHP 
YVNPHMEHYL RSVHSSPTLS MISAARGLSP ADVAQEHLKE RGLFGLPAPG TTPSDYYHQM 
TLVAGHPAPY GDLLMQSGGA ASAPHLHDYL NPVDVSRFSS PRVTPRLSRK RALSISPLSD 
ASLDLQRMIR TSPNSLVAYI NNSRSSSAAS GSYGHLSAGA LSPAFTFPHP INPVAYQQIL 
SQQRGLGSAF GHTPPLIQPS PTFLAQQPMA LTSINATPTQ LSSSSNCLSD TNQNKQSSES 
AVSSTVNPVA IHKRSKVKTE PEGLRPASPL ALTQGQVSGH GSCGCALPLS QEQLADLKED 
LDRDDCKQEA EVVIYETNCH WEDCTKEYDT QEQLVHHINN EHIHGEKKEF VCRWQACTRE 
QKPFKAQYML VVHMRRHTGE KPHKCTFEGC SKAYSRLENL KTHLRSHTGE KPYVCEHEGC 
NKAFSNASDR AKHQNRTHSN EKPYICKIPG CTKRYTDPSS LRKHVKTVHG PDAHVTKKQR 
NDVHLRTPLL KENGDSEAGT EPGGPESTEA SSTSQAVEDC LHVRAIKTES SGLCQSSPGA 
QSSCSSEPSP LGSAPNNDSG VEMPGTGPGS LGDLTALDDT PPGADTSALA APSAGGLQLR 
KHMTTMHRFE QLKKEKLKSL KDSCSWAGPT PHTRNTKLPP LPGSGSILEN FSGSGGGGPA 
GLLPNPRLSE LSASEVTMLS QLQERRDSST STVSSAYTVS RRSSGISPYF SSRRSSEASP 
LGAGRPHNAS SADSYDPIST DASRRSSEAS QCSGGSGLLN LTPAQQYSLR AKYAAATGGP 
PPTPLPGLER MSLRTRLALL DAPERTLPAG CPRPLGPRRG SDGPTYGHGH AGAAPAFPHE 
APGGGARRAS DPVRRPDALS LPRVQRFHST HNVNPGPLPP CADRRGLRLQ SHPSTDGGLA 
RGAYSPRPPS ISENVAMEAV AAGVDGAGPE ADLGLPEDDL VLPDDVVQYI KAHASGALDE 
GTGQVYPTES TGFSDNPRLP SPGLHGQRRM VAADSNVGPS APMLGGCQLG FGAPSSLNKN 
NMPVQWNEVS SGTVDALASQ VKPPPFPQGN LAVVQQKPAF GQYPGYSPQG LQASPGGLDS 
TQPHLQPRSG APSQGIPRVN YMQQLRQPVA GSQCPGMTTT MSPHACYGQV HPQLSPSTIS 
GALNQFPQSC SNMPAKPGHL GHPQQTEVAP DPTTMGNRHR ELGVPDSALA GVPPPHPVQS 
YPQQSHHLAA SMSQEGYHQV PSLLPARQPG FMEPQTGPMG VATAGFGLVQ PRPPLEPSPT 
GRHRGVRAVQ QQLAYARATG HAMAAMPSSQ ETAEAVPKGA MGNMGSVPPQ PPPQDAGGAP 
DHSMLYYYGQ IHMYEQDGGL ENLGSCQVMR SQPPQPQACQ DSIQPQPLPS PGVNQVSSTV 
DSQLLEAPQI DFDAIMDDGD HSSLFSGALS PSLLHSLSQN SSRLTTPRNS LTLPSIPAGI 
SNMAVGDMSS MLTSLAEESK FLNMMT

Genular Protein ID: 809822939

Symbol: Q1PSW9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q1PSW9

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 2 GeneTree 1 HGNC 1 HOGENOM 1 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PeptideAtlas 1 PharmGKB 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 82
  • Mass: 8504
  • Checksum: E92C6B879545D146
  • Sequence:
    • METSASATAS EKQEAKSGIL EAAGFPDPGK KASPLVVAAA AAAAVAAQGV PQHLLPPFHA 
PLPIDMRHQE GRYHYEPHSV HG

Genular Protein ID: 3343770600

Symbol: Q59FV5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59FV5

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 1121
  • Mass: 118303
  • Checksum: DA56454863F2C56E
  • Sequence:
    • EKKEFVCRWQ ACTREQKPFK AQYMLVVHMR RHTGEKPHKC TFEGCSKAYS RLENLKTHLR 
SHTGEKPYVC EHEGCNKAFS NASDRAKHQN RTHSNEKPYI CKIPGCTKRY TDPSSLRKHV 
KTVHGPDAHV TKKQRNDVHL RTPLLKENGD SEAGTEPGGP ESTEASSTSQ AVEDCLHVRA 
IKTESSGLCQ SSPGAQSSCS SEPSPLGSAP NNDSGVEMPG TGPGSLGDLT ALDDTPPGAD 
TSALAAPSAG GLQLRKHMTT MHRFEQLKKE KLKSLKDSCS WAGPTPHTRN TKLPPLPGSG 
SILENFSGSG GGGPAGLLPN PRLSELSASE VTMLSQLQER RDSSTSTVSS AYTVSRRSSG 
ISPYFSSRRS SEASPLGAGR PHNASSADSY DPISTDASRR SSEASQCSGG SGLLNLTPAQ 
QYSLRAKYAA ATGGPPPTPL PGLERMSLRT RLALLDAPER TLPAGCPRPL GPRRGSDGPT 
YGHGHAGAAP AFPHEAPGGG ARRASDPVRR PDALSLPRVQ RFHSTHNVNP GPLPPCADRR 
GLRLQSHPST DGGLARGAYS PRPPSISENV AMEAVAAGVD GAGPEADLGL PEDDLVLPDD 
VVQYIKAHAS GALDEGTGQV YPTESTGFSD NPRLPSPGLH GQRRMVAADS NVGPSAPMLG 
GCQLGFGAPS SLNKNNMPVQ WNEVSSGTVD ALASQVKPPP FPQGNLAVVQ QKPAFGQYPG 
YSPQGLQASP GGLDSTQPHL QPRSGAPSQG IPRVNYMQQL RQPVAGSQCP GMTTTMSPHA 
CYGQVHPQLS PSTISGALNQ FPQSCSNMPA KPGHLGHPQQ TEVAPDPTTM GNRHRELGVP 
DSALAGVPPP HPVQSYPQQS HHLAASMSQE GYHQVPSLLP ARQPGFMEPQ TGPMGVATAG 
FGLVQPRPPL EPSPTGRHRG VRAVQQQLAY ARATGHAMAA MPSSQETAEA VPKGAMGNMG 
SVPPQPPPQD AGGAPDHSML YYYGQIHMYE QDGGLENLGS CQVMRSQPPQ PQACQDSIQP 
QPLPSPGVNQ VSSTVDSQLL EAPQIDFDAI MDDGDHSSLF SGALSPSLLH SLSQNSSRLT 
TPRNSLTLPS IPAGISNMAV GDMSSMLTSL AEESKFLNMM T

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.