Details for: GPI

Gene ID: 2821

Symbol: GPI

Ensembl ID: ENSG00000105220

Description: glucose-6-phosphate isomerase

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.69
    Marker Score: 11278
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 2.6
    Marker Score: 3140
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 2.54
    Marker Score: 5167
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.48
    Marker Score: 49289
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 2.47
    Marker Score: 55217
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 2.38
    Marker Score: 999
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 2.38
    Marker Score: 2246
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.34
    Marker Score: 1365
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 2.3
    Marker Score: 6168
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 2.28
    Marker Score: 6203
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 2.24
    Marker Score: 3169
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.23
    Marker Score: 14258
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.21
    Marker Score: 2673
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.19
    Marker Score: 83267
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 2.18
    Marker Score: 1141
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.17
    Marker Score: 21834
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.17
    Marker Score: 16620
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.13
    Marker Score: 78559
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.11
    Marker Score: 8752
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 2.11
    Marker Score: 2238
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.09
    Marker Score: 31313
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 2.06
    Marker Score: 654
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 2.05
    Marker Score: 15250
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.03
    Marker Score: 43363
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.03
    Marker Score: 4448
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.01
    Marker Score: 7753
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 2
    Marker Score: 4982
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.98
    Marker Score: 20455
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1.97
    Marker Score: 22930
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.96
    Marker Score: 120316
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.95
    Marker Score: 18364
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 1.92
    Marker Score: 774
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.89
    Marker Score: 1105
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 1.87
    Marker Score: 4727
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 1.84
    Marker Score: 1988
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.84
    Marker Score: 17496
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.83
    Marker Score: 2468
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.8
    Marker Score: 492
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 1.79
    Marker Score: 2158
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.78
    Marker Score: 15268
  • Cell Name: myelocyte (CL0002193)
    Fold Change: 1.78
    Marker Score: 767
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.77
    Marker Score: 2608
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.77
    Marker Score: 7187
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 1.75
    Marker Score: 2329
  • Cell Name: Unknown (CL0002371)
    Fold Change: 1.75
    Marker Score: 1857
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 1.75
    Marker Score: 2895
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 1.73
    Marker Score: 3375
  • Cell Name: Unknown (CL0000548)
    Fold Change: 1.71
    Marker Score: 1245
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 1.69
    Marker Score: 16775.5
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.68
    Marker Score: 532
  • Cell Name: stem cell (CL0000034)
    Fold Change: 1.68
    Marker Score: 3989
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 1.67
    Marker Score: 2396
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.67
    Marker Score: 1444
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 1.65
    Marker Score: 1599
  • Cell Name: fetal cardiomyocyte (CL0002495)
    Fold Change: 1.65
    Marker Score: 544
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.64
    Marker Score: 796
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 1.64
    Marker Score: 3208
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 1.63
    Marker Score: 2909
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 1.63
    Marker Score: 7531
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.62
    Marker Score: 2294
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 1.61
    Marker Score: 847
  • Cell Name: pulmonary ionocyte (CL0017000)
    Fold Change: 1.61
    Marker Score: 987
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 1.61
    Marker Score: 2013
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.6
    Marker Score: 477
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.59
    Marker Score: 88655
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 1.59
    Marker Score: 5003
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.58
    Marker Score: 10284
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 1.58
    Marker Score: 4951
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: 1.57
    Marker Score: 9534
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 1.56
    Marker Score: 12203
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 1.56
    Marker Score: 7474
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 1.55
    Marker Score: 568
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.55
    Marker Score: 527
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 1.54
    Marker Score: 2532
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 1.54
    Marker Score: 1288.5
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 1.54
    Marker Score: 6596
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.53
    Marker Score: 2369
  • Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
    Fold Change: 1.53
    Marker Score: 515
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.52
    Marker Score: 1017
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.51
    Marker Score: 1594
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 1.51
    Marker Score: 1095
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 1.51
    Marker Score: 79837
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 1.51
    Marker Score: 2627
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 1.5
    Marker Score: 12948
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 1.5
    Marker Score: 1315
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 1.49
    Marker Score: 1596
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.48
    Marker Score: 1358
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 1.47
    Marker Score: 423
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 1.47
    Marker Score: 1002
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.46
    Marker Score: 50731.5
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.45
    Marker Score: 3303
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 1.44
    Marker Score: 2550
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.44
    Marker Score: 3603
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.44
    Marker Score: 343
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 1.43
    Marker Score: 459
  • Cell Name: oocyte (CL0000023)
    Fold Change: 1.43
    Marker Score: 353
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 1.43
    Marker Score: 4002
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 1.42
    Marker Score: 36383
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: 1.41
    Marker Score: 1257
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.41
    Marker Score: 4998.5

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Other Information

**Key characteristics** - GPI is a glycolytic enzyme that catalyzes the isomerization of glucose-6-phosphate to 6-phosphoglucomutase (6PGM). - It is a key enzyme in the pentose phosphate pathway, which is involved in the synthesis of nucleotides and nucleic acids. - GPI is also involved in the regulation of inflammation and cell growth. **Pathways and functions** - GPI is involved in the regulation of inflammation through the production of inflammatory cytokines. - It is expressed in endothelial cells of blood vessels and can be activated by inflammatory signals, leading to the production of pro-inflammatory cytokines and chemokines. - GPI is also involved in the regulation of cell growth through the control of cell proliferation and differentiation. **Clinical significance** - Mutations in GPI genes have been linked to several human diseases, including cancer, inflammation, and diabetes. - GPI inhibitors are being investigated as potential therapeutic agents for these diseases. **Additional information** - GPI is a highly conserved enzyme with a wide distribution in the human body. - It is expressed in high levels in epithelial cells, where it is involved in the regulation of cell growth, differentiation, and inflammation. - GPI is a regulated protein that is controlled by various factors, including growth factors, cytokines, and hormones.

Genular Protein ID: 568552359

Symbol: G6PI_HUMAN

Name: N/A

UniProtKB Accession Codes:

P06744 B4DG39 Q9BRD3 Q9BSK5 Q9UHE6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CPTAC 1 CPTC 1 CTD 1 ChEBI 8 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 10 EC 1 EMBL 8 EMDB 1 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 33 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HAMAP 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 MoonDB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 12 PDBsum 9 PIR 1 PRIDE 1 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 4 RefSeq 5 Rhea 1 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 2 TreeFam 1 UCSC 1 UniPathway 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10727272

Title: Cloning of a glucose phosphate isomerase/neuroleukin-like sperm antigen involved in sperm agglutination.

PubMed ID: 10727272

DOI: 10.1095/biolreprod62.4.1016

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2387591

Title: Characterization of the 5' end of the gene for human glucose phosphate isomerase (GPI).

PubMed ID: 2387591

DOI: 10.1016/0888-7543(90)90212-d

PubMed ID: 3352745

Title: Mouse glucose-6-phosphate isomerase and neuroleukin have identical 3' sequences.

PubMed ID: 3352745

DOI: 10.1038/332455a0

PubMed ID: 11004567

Title: Phosphohexose isomerase/autocrine motility factor/neuroleukin/maturation factor is a multifunctional phosphoprotein.

PubMed ID: 11004567

DOI: 10.1016/s0167-4838(00)00075-3

PubMed ID: 11437381

Title: Tumor autocrine motility factor is an angiogenic factor that stimulates endothelial cell motility.

PubMed ID: 11437381

DOI: 10.1006/bbrc.2001.5135

PubMed ID: 12163179

Title: Species specificity of the cytokine function of phosphoglucose isomerase.

PubMed ID: 12163179

DOI: 10.1016/s0014-5793(02)03072-7

PubMed ID: 16139798

Title: Proteomic identification of proteins conjugated to ISG15 in mouse and human cells.

PubMed ID: 16139798

DOI: 10.1016/j.bbrc.2005.08.132

PubMed ID: 15637053

Title: Differential regulation of phosphoglucose isomerase/autocrine motility factor activities by protein kinase CK2 phosphorylation.

PubMed ID: 15637053

DOI: 10.1074/jbc.m409457200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21908771

Title: The first identification of lysine malonylation substrates and its regulatory enzyme.

PubMed ID: 21908771

DOI: 10.1074/mcp.m111.012658

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 29775581

Title: p300-mediated lysine 2-hydroxyisobutyrylation regulates glycolysis.

PubMed ID: 29775581

DOI: 10.1016/j.molcel.2018.04.011

PubMed ID: 11371164

Title: The crystal structure of human phosphoglucose isomerase at 1.6 A resolution: implications for catalytic mechanism, cytokine activity and haemolytic anaemia.

PubMed ID: 11371164

DOI: 10.1006/jmbi.2001.4680

PubMed ID: 12054796

Title: Inhibition mechanism of cytokine activity of human autocrine motility factor examined by crystal structure analyses and site-directed mutagenesis studies.

PubMed ID: 12054796

DOI: 10.1016/s0022-2836(02)00186-9

PubMed ID: 12777791

Title: The structure of human phosphoglucose isomerase complexed with a transition-state analogue.

PubMed ID: 12777791

DOI: 10.1107/s0907444903007352

PubMed ID: 12573240

Title: Crystal structure of human phosphoglucose isomerase and analysis of the initial catalytic steps.

PubMed ID: 12573240

DOI: 10.1016/s1570-9639(02)00464-8

PubMed ID: 8499925

Title: DNA sequence abnormalities in human glucose 6-phosphate isomerase deficiency.

PubMed ID: 8499925

DOI: 10.1093/hmg/2.3.327

PubMed ID: 7989588

Title: The characterization of gene mutations for human glucose phosphate isomerase deficiency associated with chronic hemolytic anemia.

PubMed ID: 7989588

DOI: 10.1172/jci117597

PubMed ID: 8822952

Title: Study of the molecular defects in glucose phosphate isomerase-deficient patients affected by chronic hemolytic anemia.

PubMed ID: 8822952

PubMed ID: 8822954

Title: Molecular analysis of glucose phosphate isomerase deficiency associated with hereditary hemolytic anemia.

PubMed ID: 8822954

PubMed ID: 9446754

Title: Glucosephosphate isomerase (GPI) deficiency mutations associated with hereditary nonspherocytic hemolytic anemia (HNSHA).

PubMed ID: 9446754

DOI: 10.1006/bcmd.1997.0157

PubMed ID: 9856489

Title: Molecular basis of neurological dysfunction coupled with haemolytic anaemia in human glucose-6-phosphate isomerase (GPI) deficiency.

PubMed ID: 9856489

DOI: 10.1007/s004390050849

PubMed ID: 28803808

Title: Two novel mutations (p.(Ser160Pro) and p.(Arg472Cys)) causing glucose-6-phosphate isomerase deficiency are associated with erythroid dysplasia and inappropriately suppressed hepcidin.

PubMed ID: 28803808

DOI: 10.1016/j.bcmd.2017.04.003

Sequence Information:

  • Length: 558
  • Mass: 63147
  • Checksum: 7C8E95277BDC79A6
  • Sequence:
    • MAALTRDPQF QKLQQWYREH RSELNLRRLF DANKDRFNHF SLTLNTNHGH ILVDYSKNLV 
TEDVMRMLVD LAKSRGVEAA RERMFNGEKI NYTEGRAVLH VALRNRSNTP ILVDGKDVMP 
EVNKVLDKMK SFCQRVRSGD WKGYTGKTIT DVINIGIGGS DLGPLMVTEA LKPYSSGGPR 
VWYVSNIDGT HIAKTLAQLN PESSLFIIAS KTFTTQETIT NAETAKEWFL QAAKDPSAVA 
KHFVALSTNT TKVKEFGIDP QNMFEFWDWV GGRYSLWSAI GLSIALHVGF DNFEQLLSGA 
HWMDQHFRTT PLEKNAPVLL ALLGIWYINC FGCETHAMLP YDQYLHRFAA YFQQGDMESN 
GKYITKSGTR VDHQTGPIVW GEPGTNGQHA FYQLIHQGTK MIPCDFLIPV QTQHPIRKGL 
HHKILLANFL AQTEALMRGK STEEARKELQ AAGKSPEDLE RLLPHKVFEG NRPTNSIVFT 
KLTPFMLGAL VAMYEHKIFV QGIIWDINSF DQWGVELGKQ LAKKIEPELD GSAQVTSHDA 
STNGLINFIK QQREARVQ

Genular Protein ID: 94659253

Symbol: A0A2U3TZU2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A2U3TZU2

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CDD 2 CTD 1 ChEBI 2 ChiTaRS 1 DNASU 1 EC 1 EMBL 2 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 1 GeneTree 1 HAMAP 1 HGNC 1 InterPro 6 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PeptideAtlas 1 Pfam 1 Proteomes 2 RefSeq 2 Rhea 1 RuleBase 1 SAM 1 SMR 1 SUPFAM 1 UniPathway 1 VEuPathDB 1

Citations:

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 597
  • Mass: 67286
  • Checksum: E8639E5C41EAC8D2
  • Sequence:
    • MVALCSLQHL GSSDPRALPT LPTATSGQRP AKRRRKSPAM AALTRDPQFQ KLQQWYREHR 
SELNLRRLFD ANKDRFNHFS LTLNTNHGHI LVDYSKNLVT EDVMRMLVDL AKSRGVEAAR 
ERMFNGEKIN YTEGRAVLHV ALRNRSNTPI LVDGKDVMPE VNKVLDKMKS FCQRVRSGDW 
KGYTGKTITD VINIGIGGSD LGPLMVTEAL KPYSSGGPRV WYVSNIDGTH IAKTLAQLNP 
ESSLFIIASK TFTTQETITN AETAKEWFLQ AAKDPSAVAK HFVALSTNTT KVKEFGIDPQ 
NMFEFWDWVG GRYSLWSAIG LSIALHVGFD NFEQLLSGAH WMDQHFRTTP LEKNAPVLLA 
LLGIWYINCF GCETHAMLPY DQYLHRFAAY FQQGDMESNG KYITKSGTRV DHQTGPIVWG 
EPGTNGQHAF YQLIHQGTKM IPCDFLIPVQ TQHPIRKGLH HKILLANFLA QTEALMRGKS 
TEEARKELQA AGKSPEDLER LLPHKVFEGN RPTNSIVFTK LTPFMLGALV AMYEHKIFVQ 
GIIWDINSFD QWGVELGKQL AKKIEPELDG SAQVTSHDAS TNGLINFIKQ QREARVQ

Genular Protein ID: 3659159084

Symbol: B4DE36_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DE36

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 2 DNASU 1 EC 1 EMBL 2 GO 7 Gene3D 1 GenomeRNAi 1 HAMAP 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PeptideAtlas 1 Pfam 1 RefSeq 1 Rhea 1 RuleBase 1 SMR 1 SUPFAM 1 UniPathway 1

Sequence Information:

  • Length: 530
  • Mass: 60186
  • Checksum: 1F3427E5C76EFD87
  • Sequence:
    • MAALTRDPQF QKLQQWYREH RSELNLRRLF DANKDRFNHF SLTLNTNHGH ILVDYSKNLV 
TEDVMRMLVD LAKSRGVEAA RERMFNGEKI NYTEGRAVLH VALRNRSNTP ILVDGKDVMP 
EVNKVLDKMK SFCQGPLMVT EALKPYSSGG PRVWYVSNID GTHIAKTLAQ LNPESSLFII 
ASKTFTTQET ITNAETAKEW FLQAAKDPSA VAKHFVALST NTTKVKEFGI DPQNMFEFWD 
WVGGRYSLWS AIGLSIALHV GFDNFEQLLS GAHWMDQHFR TTPLEKNAPV LLALLGIWYI 
NCFGCETHAM LPYDQYLHRF AAYFQQGDME SNGKYITKSG TRVDHQTGPI VWGEPGTNGQ 
HAFYQLIHQG TKMIPCDFLI PVQTQHPIRK GLHHKILLAN FLAQTEALMR GKSTEEARKE 
LQAAGKSPED LERLLPHKVF EGNRPTNSIV FTKLTPFMLG ALVAMYEHKI FVQGIIWDIN 
SFDQWGVELG KQLAKKIEPE LDGSAQVTSH DASTNGLINF IKQQREARVQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.