Details for: ANGPT1

Gene ID: 284

Symbol: ANGPT1

Ensembl ID: ENSG00000154188

Description: angiopoietin 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 119.0811
    Cell Significance Index: -18.5200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 43.6045
    Cell Significance Index: -11.0600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 40.4344
    Cell Significance Index: -19.0900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 36.7747
    Cell Significance Index: -14.9400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 15.6377
    Cell Significance Index: -14.9300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 15.0735
    Cell Significance Index: -18.5900
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 11.4228
    Cell Significance Index: 70.6700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 6.8035
    Cell Significance Index: -14.8900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 4.5995
    Cell Significance Index: -18.1500
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 4.5834
    Cell Significance Index: 38.5000
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 2.5968
    Cell Significance Index: 32.7000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 2.2713
    Cell Significance Index: 44.3300
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 1.7235
    Cell Significance Index: 24.1000
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.3817
    Cell Significance Index: 29.5400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.2648
    Cell Significance Index: 453.6800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.9625
    Cell Significance Index: 24.7400
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.7187
    Cell Significance Index: 6.3800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.5760
    Cell Significance Index: 15.4400
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.5460
    Cell Significance Index: 7.8400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.2065
    Cell Significance Index: 15.8500
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.2043
    Cell Significance Index: 5.2200
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.1907
    Cell Significance Index: 0.8300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1864
    Cell Significance Index: 128.9500
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.1635
    Cell Significance Index: 3.9900
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.1607
    Cell Significance Index: 2.5500
  • Cell Name: myometrial cell (CL0002366)
    Fold Change: 0.1606
    Cell Significance Index: 1.8500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1004
    Cell Significance Index: 45.5900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.0969
    Cell Significance Index: 1.4300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.0841
    Cell Significance Index: 1.7600
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.0723
    Cell Significance Index: 0.4900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0684
    Cell Significance Index: 13.7200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0391
    Cell Significance Index: 5.3700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0305
    Cell Significance Index: 1.4200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0281
    Cell Significance Index: 0.7700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0160
    Cell Significance Index: 2.0500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0040
    Cell Significance Index: 7.4400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0029
    Cell Significance Index: -0.0500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0059
    Cell Significance Index: -1.0700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0071
    Cell Significance Index: -13.1000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0097
    Cell Significance Index: -14.9700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0115
    Cell Significance Index: -15.6900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0118
    Cell Significance Index: -5.2000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0184
    Cell Significance Index: -11.7000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0222
    Cell Significance Index: -16.2800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0260
    Cell Significance Index: -19.6900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0267
    Cell Significance Index: -19.7700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0329
    Cell Significance Index: -20.5700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0340
    Cell Significance Index: -18.5900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0348
    Cell Significance Index: -0.9300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0372
    Cell Significance Index: -20.9700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0450
    Cell Significance Index: -8.9400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0500
    Cell Significance Index: -2.5300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0518
    Cell Significance Index: -14.8900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0520
    Cell Significance Index: -6.3900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0592
    Cell Significance Index: -3.6400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0819
    Cell Significance Index: -1.3700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0965
    Cell Significance Index: -20.3200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0966
    Cell Significance Index: -5.0300
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: -0.0986
    Cell Significance Index: -0.9000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1000
    Cell Significance Index: -10.2100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1075
    Cell Significance Index: -18.3500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1082
    Cell Significance Index: -15.7300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1158
    Cell Significance Index: -13.2700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1299
    Cell Significance Index: -1.8600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1367
    Cell Significance Index: -17.6600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1480
    Cell Significance Index: -15.4100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1547
    Cell Significance Index: -18.0300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1576
    Cell Significance Index: -18.5900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1598
    Cell Significance Index: -11.3000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1708
    Cell Significance Index: -3.4300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.1887
    Cell Significance Index: -1.1400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2148
    Cell Significance Index: -13.8600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2153
    Cell Significance Index: -17.0500
  • Cell Name: megakaryocyte progenitor cell (CL0000553)
    Fold Change: -0.2351
    Cell Significance Index: -1.6900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2439
    Cell Significance Index: -18.1800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2457
    Cell Significance Index: -12.9000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2634
    Cell Significance Index: -12.3800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2726
    Cell Significance Index: -18.3300
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -0.2794
    Cell Significance Index: -1.2900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.2885
    Cell Significance Index: -17.3200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2896
    Cell Significance Index: -16.2500
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: -0.2954
    Cell Significance Index: -3.4300
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2959
    Cell Significance Index: -6.2800
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.3077
    Cell Significance Index: -5.3200
  • Cell Name: mural cell (CL0008034)
    Fold Change: -0.3109
    Cell Significance Index: -3.7900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3360
    Cell Significance Index: -11.7700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.3446
    Cell Significance Index: -8.2700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3527
    Cell Significance Index: -18.3200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3877
    Cell Significance Index: -17.1500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3896
    Cell Significance Index: -13.5400
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.4299
    Cell Significance Index: -4.9200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4322
    Cell Significance Index: -13.7700
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: -0.4336
    Cell Significance Index: -4.1800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4400
    Cell Significance Index: -14.4100
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.4443
    Cell Significance Index: -11.0800
  • Cell Name: slow muscle cell (CL0000189)
    Fold Change: -0.4459
    Cell Significance Index: -6.6700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.4481
    Cell Significance Index: -16.9700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4557
    Cell Significance Index: -12.1900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4570
    Cell Significance Index: -13.4600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.4625
    Cell Significance Index: -12.9300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** ANGPT1 is a secreted protein that belongs to the angiopoietin family, which consists of four members: angiopoietin-1, angiopoietin-2, angiopoietin-3, and angiopoietin-4. ANGPT1 is primarily expressed in the vascular endothelium, where it regulates angiogenesis, a process crucial for tissue development, growth, and repair. ANGPT1 also interacts with its receptor, Tie2, to modulate signaling pathways involved in cell adhesion, migration, and proliferation. **Pathways and Functions** ANGPT1's primary function is to regulate angiogenesis, a process that involves the formation of new blood vessels from pre-existing ones. ANGPT1 achieves this by binding to its receptor, Tie2, which is expressed on the surface of endothelial cells. The binding of ANGPT1 to Tie2 triggers a signaling cascade that promotes angiogenesis by regulating the expression of pro-angiogenic genes and inhibiting anti-angiogenic factors. ANGPT1 also plays a role in cell adhesion and migration, influencing the behavior of endothelial cells and their interactions with the extracellular matrix. In addition to its role in angiogenesis, ANGPT1 is involved in various other signaling pathways, including the MAPK/ERK pathway, which regulates cell proliferation, differentiation, and survival. ANGPT1 also modulates the activity of immune cells, such as macrophages and T-cells, by regulating cytokine production and cell adhesion. **Clinical Significance** ANGPT1's dysregulation has been implicated in various diseases, including cancer, cardiovascular disease, and autoimmune disorders. In cancer, ANGPT1 promotes angiogenesis, tumor growth, and metastasis. In cardiovascular disease, ANGPT1 plays a role in the development of atherosclerosis and the formation of blood clots. In autoimmune disorders, ANGPT1 has been linked to the regulation of immune cell function and the production of cytokines. In the context of immunology, ANGPT1 has been shown to regulate the activity of immune cells, including macrophages and T-cells. ANGPT1's interaction with its receptor, Tie2, modulates the production of cytokines and the expression of adhesion molecules, influencing the behavior of immune cells and their interactions with the extracellular matrix. **Conclusion** In conclusion, ANGPT1 is a multifunctional protein that plays a critical role in various physiological and pathological processes, including angiogenesis, cell adhesion, and signaling pathways. Its dysregulation has been implicated in various diseases, including cancer, cardiovascular disease, and autoimmune disorders. Further research is needed to fully understand the mechanisms by which ANGPT1 regulates immune cell function and the production of cytokines, and to explore its potential as a therapeutic target for the treatment of these diseases. **Recommendations for Future Research** 1. Investigate the mechanisms by which ANGPT1 regulates angiogenesis and cell adhesion in different tissues and diseases. 2. Explore the role of ANGPT1 in the development and progression of cancer, cardiovascular disease, and autoimmune disorders. 3. Investigate the potential of ANGPT1 as a therapeutic target for the treatment of these diseases. 4. Examine the interactions between ANGPT1 and other proteins, including its receptor, Tie2, and other signaling molecules. 5. Investigate the role of ANGPT1 in the regulation of immune cell function and the production of cytokines. By further understanding the mechanisms by which ANGPT1 regulates various physiological and pathological processes, researchers can uncover new insights into the regulation of immune cell function and the production of cytokines, and explore its potential as a therapeutic target for the treatment of various diseases.

Genular Protein ID: 754983

Symbol: ANGP1_HUMAN

Name: Angiopoietin-1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8980223

Title: Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning.

PubMed ID: 8980223

DOI: 10.1016/s0092-8674(00)81812-7

PubMed ID: 7584026

Title: Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1.

PubMed ID: 7584026

DOI: 10.1093/dnares/1.1.27

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 9204896

Title: Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis.

PubMed ID: 9204896

DOI: 10.1126/science.277.5322.55

PubMed ID: 12427764

Title: Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats.

PubMed ID: 12427764

DOI: 10.1074/jbc.m208550200

PubMed ID: 15284220

Title: Biological characterization of angiopoietin-3 and angiopoietin-4.

PubMed ID: 15284220

DOI: 10.1096/fj.03-1466com

PubMed ID: 18425120

Title: Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1.

PubMed ID: 18425120

DOI: 10.1038/ncb1714

PubMed ID: 18425119

Title: Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts.

PubMed ID: 18425119

DOI: 10.1038/ncb1715

PubMed ID: 19234476

Title: Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system.

PubMed ID: 19234476

DOI: 10.1038/nrm2639

PubMed ID: 20054809

Title: Angiopoietin-1/Tie2 receptor signaling in vascular quiescence and angiogenesis.

PubMed ID: 20054809

DOI: 10.14670/hh-25.387

PubMed ID: 20651738

Title: Targeting the ANGPT-TIE2 pathway in malignancy.

PubMed ID: 20651738

DOI: 10.1038/nrc2894

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 29323190

Title: Angiopoietins bind thrombomodulin and inhibit its function as a thrombin cofactor.

PubMed ID: 29323190

DOI: 10.1038/s41598-017-18912-8

PubMed ID: 28601681

Title: Mutation of the angiopoietin-1 gene (ANGPT1) associates with a new type of hereditary angioedema.

PubMed ID: 28601681

DOI: 10.1016/j.jaci.2017.05.020

PubMed ID: 30689269

Title: Angiopoietin-1 haploinsufficiency affects the endothelial barrier and causes hereditary angioedema.

PubMed ID: 30689269

DOI: 10.1111/cea.13349

Sequence Information:

  • Length: 498
  • Mass: 57513
  • Checksum: 5D5FA63AEF6BE920
  • Sequence:
  • MTVFLSFAFL AAILTHIGCS NQRRSPENSG RRYNRIQHGQ CAYTFILPEH DGNCRESTTD 
    QYNTNALQRD APHVEPDFSS QKLQHLEHVM ENYTQWLQKL ENYIVENMKS EMAQIQQNAV 
    QNHTATMLEI GTSLLSQTAE QTRKLTDVET QVLNQTSRLE IQLLENSLST YKLEKQLLQQ 
    TNEILKIHEK NSLLEHKILE MEGKHKEELD TLKEEKENLQ GLVTRQTYII QELEKQLNRA 
    TTNNSVLQKQ QLELMDTVHN LVNLCTKEGV LLKGGKREEE KPFRDCADVY QAGFNKSGIY 
    TIYINNMPEP KKVFCNMDVN GGGWTVIQHR EDGSLDFQRG WKEYKMGFGN PSGEYWLGNE 
    FIFAITSQRQ YMLRIELMDW EGNRAYSQYD RFHIGNEKQN YRLYLKGHTG TAGKQSSLIL 
    HGADFSTKDA DNDNCMCKCA LMLTGGWWFD ACGPSNLNGM FYTAGQNHGK LNGIKWHYFK 
    GPSYSLRSTT MMIRPLDF

Genular Protein ID: 377396238

Symbol: B4DTQ9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 298
  • Mass: 34332
  • Checksum: 9A000C6415BC98E7
  • Sequence:
  • MEGKHKEELD TLKEEKENLQ GLVTRQTYII QELEKQLNRA TTNNSVLQKQ QLELMDTVHN 
    LVNLCTKEGV LLKGGKREEE KPFRDCADVY QAGFNKSGIY TIYINNMPEP KKVFCNMDVN 
    GGGWTVIQHR EDGSLDFQRG WKEYKMGFGN PSGEYWLGNE FIFAITSQRQ YMLRIELMDW 
    EGNRAYSQYD RFHIGNEKQN YRLYLKGHTG TAGKQSSLIL HGADFSTKDA DNDNCMCKCA 
    LMLTGGWWFD ACGPSNLNGM FYTAGQNHGK LNGIKWHYFK GPSYSLRSTT MMIRPLDF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.