Details for: ANGPT1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 119.0811
Cell Significance Index: -18.5200 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 43.6045
Cell Significance Index: -11.0600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 40.4344
Cell Significance Index: -19.0900 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 36.7747
Cell Significance Index: -14.9400 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 15.6377
Cell Significance Index: -14.9300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 15.0735
Cell Significance Index: -18.5900 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 11.4228
Cell Significance Index: 70.6700 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 6.8035
Cell Significance Index: -14.8900 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 4.5995
Cell Significance Index: -18.1500 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 4.5834
Cell Significance Index: 38.5000 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: 2.5968
Cell Significance Index: 32.7000 - Cell Name: preadipocyte (CL0002334)
Fold Change: 2.2713
Cell Significance Index: 44.3300 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: 1.7235
Cell Significance Index: 24.1000 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 1.3817
Cell Significance Index: 29.5400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.2648
Cell Significance Index: 453.6800 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.9625
Cell Significance Index: 24.7400 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 0.7187
Cell Significance Index: 6.3800 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.5760
Cell Significance Index: 15.4400 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.5460
Cell Significance Index: 7.8400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.2065
Cell Significance Index: 15.8500 - Cell Name: pro-T cell (CL0000827)
Fold Change: 0.2043
Cell Significance Index: 5.2200 - Cell Name: subcutaneous adipocyte (CL0002521)
Fold Change: 0.1907
Cell Significance Index: 0.8300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1864
Cell Significance Index: 128.9500 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 0.1635
Cell Significance Index: 3.9900 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.1607
Cell Significance Index: 2.5500 - Cell Name: myometrial cell (CL0002366)
Fold Change: 0.1606
Cell Significance Index: 1.8500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.1004
Cell Significance Index: 45.5900 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.0969
Cell Significance Index: 1.4300 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.0841
Cell Significance Index: 1.7600 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 0.0723
Cell Significance Index: 0.4900 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0684
Cell Significance Index: 13.7200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0391
Cell Significance Index: 5.3700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0305
Cell Significance Index: 1.4200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.0281
Cell Significance Index: 0.7700 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0160
Cell Significance Index: 2.0500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0040
Cell Significance Index: 7.4400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0029
Cell Significance Index: -0.0500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0059
Cell Significance Index: -1.0700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0071
Cell Significance Index: -13.1000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0097
Cell Significance Index: -14.9700 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0115
Cell Significance Index: -15.6900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0118
Cell Significance Index: -5.2000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0184
Cell Significance Index: -11.7000 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0222
Cell Significance Index: -16.2800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0260
Cell Significance Index: -19.6900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0267
Cell Significance Index: -19.7700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0329
Cell Significance Index: -20.5700 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0340
Cell Significance Index: -18.5900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0348
Cell Significance Index: -0.9300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0372
Cell Significance Index: -20.9700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0450
Cell Significance Index: -8.9400 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0500
Cell Significance Index: -2.5300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0518
Cell Significance Index: -14.8900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0520
Cell Significance Index: -6.3900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0592
Cell Significance Index: -3.6400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0819
Cell Significance Index: -1.3700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0965
Cell Significance Index: -20.3200 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0966
Cell Significance Index: -5.0300 - Cell Name: preosteoblast (CL0007010)
Fold Change: -0.0986
Cell Significance Index: -0.9000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1000
Cell Significance Index: -10.2100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1075
Cell Significance Index: -18.3500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1082
Cell Significance Index: -15.7300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1158
Cell Significance Index: -13.2700 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.1299
Cell Significance Index: -1.8600 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1367
Cell Significance Index: -17.6600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1480
Cell Significance Index: -15.4100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1547
Cell Significance Index: -18.0300 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1576
Cell Significance Index: -18.5900 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1598
Cell Significance Index: -11.3000 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.1708
Cell Significance Index: -3.4300 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.1887
Cell Significance Index: -1.1400 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.2148
Cell Significance Index: -13.8600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2153
Cell Significance Index: -17.0500 - Cell Name: megakaryocyte progenitor cell (CL0000553)
Fold Change: -0.2351
Cell Significance Index: -1.6900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2439
Cell Significance Index: -18.1800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2457
Cell Significance Index: -12.9000 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2634
Cell Significance Index: -12.3800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.2726
Cell Significance Index: -18.3300 - Cell Name: perivascular cell (CL4033054)
Fold Change: -0.2794
Cell Significance Index: -1.2900 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.2885
Cell Significance Index: -17.3200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.2896
Cell Significance Index: -16.2500 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: -0.2954
Cell Significance Index: -3.4300 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.2959
Cell Significance Index: -6.2800 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.3077
Cell Significance Index: -5.3200 - Cell Name: mural cell (CL0008034)
Fold Change: -0.3109
Cell Significance Index: -3.7900 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.3360
Cell Significance Index: -11.7700 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.3446
Cell Significance Index: -8.2700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.3527
Cell Significance Index: -18.3200 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.3877
Cell Significance Index: -17.1500 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.3896
Cell Significance Index: -13.5400 - Cell Name: astrocyte (CL0000127)
Fold Change: -0.4299
Cell Significance Index: -4.9200 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.4322
Cell Significance Index: -13.7700 - Cell Name: connective tissue cell (CL0002320)
Fold Change: -0.4336
Cell Significance Index: -4.1800 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.4400
Cell Significance Index: -14.4100 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.4443
Cell Significance Index: -11.0800 - Cell Name: slow muscle cell (CL0000189)
Fold Change: -0.4459
Cell Significance Index: -6.6700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.4481
Cell Significance Index: -16.9700 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.4557
Cell Significance Index: -12.1900 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.4570
Cell Significance Index: -13.4600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.4625
Cell Significance Index: -12.9300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 754983
Symbol: ANGP1_HUMAN
Name: Angiopoietin-1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8980223
Title: Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning.
PubMed ID: 8980223
PubMed ID: 7584026
Title: Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1.
PubMed ID: 7584026
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 16421571
Title: DNA sequence and analysis of human chromosome 8.
PubMed ID: 16421571
DOI: 10.1038/nature04406
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12168954
Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
PubMed ID: 12168954
PubMed ID: 9204896
Title: Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis.
PubMed ID: 9204896
PubMed ID: 12427764
Title: Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats.
PubMed ID: 12427764
PubMed ID: 15284220
Title: Biological characterization of angiopoietin-3 and angiopoietin-4.
PubMed ID: 15284220
PubMed ID: 18425120
Title: Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1.
PubMed ID: 18425120
DOI: 10.1038/ncb1714
PubMed ID: 18425119
Title: Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts.
PubMed ID: 18425119
DOI: 10.1038/ncb1715
PubMed ID: 19234476
Title: Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system.
PubMed ID: 19234476
DOI: 10.1038/nrm2639
PubMed ID: 20054809
Title: Angiopoietin-1/Tie2 receptor signaling in vascular quiescence and angiogenesis.
PubMed ID: 20054809
DOI: 10.14670/hh-25.387
PubMed ID: 20651738
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 29323190
Title: Angiopoietins bind thrombomodulin and inhibit its function as a thrombin cofactor.
PubMed ID: 29323190
PubMed ID: 28601681
Title: Mutation of the angiopoietin-1 gene (ANGPT1) associates with a new type of hereditary angioedema.
PubMed ID: 28601681
PubMed ID: 30689269
Title: Angiopoietin-1 haploinsufficiency affects the endothelial barrier and causes hereditary angioedema.
PubMed ID: 30689269
DOI: 10.1111/cea.13349
Sequence Information:
- Length: 498
- Mass: 57513
- Checksum: 5D5FA63AEF6BE920
- Sequence:
MTVFLSFAFL AAILTHIGCS NQRRSPENSG RRYNRIQHGQ CAYTFILPEH DGNCRESTTD QYNTNALQRD APHVEPDFSS QKLQHLEHVM ENYTQWLQKL ENYIVENMKS EMAQIQQNAV QNHTATMLEI GTSLLSQTAE QTRKLTDVET QVLNQTSRLE IQLLENSLST YKLEKQLLQQ TNEILKIHEK NSLLEHKILE MEGKHKEELD TLKEEKENLQ GLVTRQTYII QELEKQLNRA TTNNSVLQKQ QLELMDTVHN LVNLCTKEGV LLKGGKREEE KPFRDCADVY QAGFNKSGIY TIYINNMPEP KKVFCNMDVN GGGWTVIQHR EDGSLDFQRG WKEYKMGFGN PSGEYWLGNE FIFAITSQRQ YMLRIELMDW EGNRAYSQYD RFHIGNEKQN YRLYLKGHTG TAGKQSSLIL HGADFSTKDA DNDNCMCKCA LMLTGGWWFD ACGPSNLNGM FYTAGQNHGK LNGIKWHYFK GPSYSLRSTT MMIRPLDF
Genular Protein ID: 377396238
Symbol: B4DTQ9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16421571
Title: DNA sequence and analysis of human chromosome 8.
PubMed ID: 16421571
DOI: 10.1038/nature04406
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 298
- Mass: 34332
- Checksum: 9A000C6415BC98E7
- Sequence:
MEGKHKEELD TLKEEKENLQ GLVTRQTYII QELEKQLNRA TTNNSVLQKQ QLELMDTVHN LVNLCTKEGV LLKGGKREEE KPFRDCADVY QAGFNKSGIY TIYINNMPEP KKVFCNMDVN GGGWTVIQHR EDGSLDFQRG WKEYKMGFGN PSGEYWLGNE FIFAITSQRQ YMLRIELMDW EGNRAYSQYD RFHIGNEKQN YRLYLKGHTG TAGKQSSLIL HGADFSTKDA DNDNCMCKCA LMLTGGWWFD ACGPSNLNGM FYTAGQNHGK LNGIKWHYFK GPSYSLRSTT MMIRPLDF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.