Details for: GRIA1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: Purkinje cell (CL0000121)
Fold Change: 5.98
Marker Score: 201,964 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 4.05
Marker Score: 18,759 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 3.1
Marker Score: 8,852 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 3.01
Marker Score: 5,056 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.91
Marker Score: 57,788 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.84
Marker Score: 21,743 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.83
Marker Score: 42,373 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.63
Marker Score: 100,025 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.62
Marker Score: 10,878 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 2.57
Marker Score: 3,619 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.44
Marker Score: 90,168 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.36
Marker Score: 9,115 - Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
Fold Change: 2.31
Marker Score: 4,774 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 2.29
Marker Score: 4,343 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 2.15
Marker Score: 20,191 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.06
Marker Score: 126,753 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 2.03
Marker Score: 20,919 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 2.02
Marker Score: 1,121 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 1.93
Marker Score: 8,050 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.92
Marker Score: 18,248 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.88
Marker Score: 16,130 - Cell Name: neuron (CL0000540)
Fold Change: 1.82
Marker Score: 7,400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.72
Marker Score: 660 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.65
Marker Score: 2,552 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 1.58
Marker Score: 1,968 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.53
Marker Score: 3,112 - Cell Name: mural cell (CL0008034)
Fold Change: 1.46
Marker Score: 167,565 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.42
Marker Score: 798 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 1.33
Marker Score: 598 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 1.32
Marker Score: 687 - Cell Name: microglial cell (CL0000129)
Fold Change: 1.3
Marker Score: 2,366 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 1.26
Marker Score: 1,008 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 1.17
Marker Score: 1,460 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 1.17
Marker Score: 475 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.15
Marker Score: 18,033 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.03
Marker Score: 619 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 1
Marker Score: 1,236 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,795 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,019 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,406 - Cell Name: sympathetic neuron (CL0011103)
Fold Change: 0.97
Marker Score: 321 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,426 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.94
Marker Score: 5,355 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.92
Marker Score: 19,583 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.92
Marker Score: 2,743 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,296 - Cell Name: ganglion interneuron (CL0000397)
Fold Change: 0.87
Marker Score: 264 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.87
Marker Score: 271 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,265 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 0.78
Marker Score: 584 - Cell Name: brush cell (CL0002204)
Fold Change: 0.77
Marker Score: 706 - Cell Name: goblet cell (CL0000160)
Fold Change: 0.77
Marker Score: 5,105 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.76
Marker Score: 396 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.74
Marker Score: 486 - Cell Name: Mueller cell (CL0000636)
Fold Change: 0.73
Marker Score: 1,016 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 0.73
Marker Score: 349 - Cell Name: bipolar neuron (CL0000103)
Fold Change: 0.72
Marker Score: 242 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.71
Marker Score: 340 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.71
Marker Score: 229 - Cell Name: stellate neuron (CL0000122)
Fold Change: 0.71
Marker Score: 3,815 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.7
Marker Score: 804 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.67
Marker Score: 579 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.66
Marker Score: 293 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: 0.63
Marker Score: 6,339 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.61
Marker Score: 365 - Cell Name: visceromotor neuron (CL0005025)
Fold Change: 0.59
Marker Score: 173 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.58
Marker Score: 461 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.55
Marker Score: 142 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.54
Marker Score: 1,273 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 0.52
Marker Score: 303 - Cell Name: myofibroblast cell (CL0000186)
Fold Change: 0.45
Marker Score: 561 - Cell Name: meningeal macrophage (CL0000879)
Fold Change: 0.45
Marker Score: 126 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 0.42
Marker Score: 1,421 - Cell Name: endothelial cell (CL0000115)
Fold Change: 0.39
Marker Score: 351 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 0.39
Marker Score: 140 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.38
Marker Score: 780 - Cell Name: interneuron (CL0000099)
Fold Change: 0.37
Marker Score: 167 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.36
Marker Score: 180 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: 0.32
Marker Score: 1,220 - Cell Name: macroglial cell (CL0000126)
Fold Change: 0.31
Marker Score: 702 - Cell Name: granule cell (CL0000120)
Fold Change: 0.29
Marker Score: 2,224 - Cell Name: retina horizontal cell (CL0000745)
Fold Change: 0.29
Marker Score: 282 - Cell Name: fibroblast (CL0000057)
Fold Change: 0.29
Marker Score: 279 - Cell Name: glial cell (CL0000125)
Fold Change: 0.29
Marker Score: 316 - Cell Name: B cell (CL0000236)
Fold Change: 0.29
Marker Score: 272 - Cell Name: macrophage (CL0000235)
Fold Change: 0.28
Marker Score: 315 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 0.28
Marker Score: 676 - Cell Name: radial glial cell (CL0000681)
Fold Change: 0.28
Marker Score: 104 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.27
Marker Score: 95 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.26
Marker Score: 1,583 - Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
Fold Change: 0.26
Marker Score: 58 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.26
Marker Score: 59 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: 0.25
Marker Score: 59 - Cell Name: cardiac mesenchymal cell (CL0000569)
Fold Change: 0.24
Marker Score: 60 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 0.24
Marker Score: 61 - Cell Name: mast cell (CL0000097)
Fold Change: 0.24
Marker Score: 140 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 0.24
Marker Score: 1,260 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: 0.23
Marker Score: 614 - Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: 0.23
Marker Score: 68 - Cell Name: Schwann cell (CL0002573)
Fold Change: 0.23
Marker Score: 80
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3604620142
Symbol: GRIA1_HUMAN
Name: AMPA-selective glutamate receptor 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1652753
Title: Molecular cloning and chromosomal localization of one of the human glutamate receptor genes.
PubMed ID: 1652753
PubMed ID: 1320959
Title: The human glutamate receptor cDNA GluR1: cloning, sequencing, expression and localization to chromosome 5.
PubMed ID: 1320959
PubMed ID: 1311100
Title: Molecular cloning, chromosomal mapping, and functional expression of human brain glutamate receptors.
PubMed ID: 1311100
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 21172611
Title: Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins.
PubMed ID: 21172611
PubMed ID: 20805473
Title: Functional comparison of the effects of TARPs and cornichons on AMPA receptor trafficking and gating.
PubMed ID: 20805473
PubMed ID: 23739980
Title: A eukaryotic specific transmembrane segment is required for tetramerization in AMPA receptors.
PubMed ID: 23739980
PubMed ID: 30135643
Title: Mechanisms of CPT1C-Dependent AMPAR Trafficking Enhancement.
PubMed ID: 30135643
PubMed ID: 23033978
Title: Diagnostic exome sequencing in persons with severe intellectual disability.
PubMed ID: 23033978
PubMed ID: 28628100
Title: Hotspots of missense mutation identify neurodevelopmental disorder genes and functional domains.
PubMed ID: 28628100
DOI: 10.1038/nn.4589
PubMed ID: 35675825
Title: Identification and functional evaluation of GRIA1 missense and truncation variants in individuals with ID: An emerging neurodevelopmental syndrome.
PubMed ID: 35675825
Sequence Information:
- Length: 906
- Mass: 101506
- Checksum: 03EA1E026D0A9A2F
- Sequence:
MQHIFAFFCT GFLGAVVGAN FPNNIQIGGL FPNQQSQEHA AFRFALSQLT EPPKLLPQID IVNISDSFEM TYRFCSQFSK GVYAIFGFYE RRTVNMLTSF CGALHVCFIT PSFPVDTSNQ FVLQLRPELQ DALISIIDHY KWQKFVYIYD ADRGLSVLQK VLDTAAEKNW QVTAVNILTT TEEGYRMLFQ DLEKKKERLV VVDCESERLN AILGQIIKLE KNGIGYHYIL ANLGFMDIDL NKFKESGANV TGFQLVNYTD TIPAKIMQQW KNSDARDHTR VDWKRPKYTS ALTYDGVKVM AEAFQSLRRQ RIDISRRGNA GDCLANPAVP WGQGIDIQRA LQQVRFEGLT GNVQFNEKGR RTNYTLHVIE MKHDGIRKIG YWNEDDKFVP AATDAQAGGD NSSVQNRTYI VTTILEDPYV MLKKNANQFE GNDRYEGYCV ELAAEIAKHV GYSYRLEIVS DGKYGARDPD TKAWNGMVGE LVYGRADVAV APLTITLVRE EVIDFSKPFM SLGISIMIKK PQKSKPGVFS FLDPLAYEIW MCIVFAYIGV SVVLFLVSRF SPYEWHSEEF EEGRDQTTSD QSNEFGIFNS LWFSLGAFMQ QGCDISPRSL SGRIVGGVWW FFTLIIISSY TANLAAFLTV ERMVSPIESA EDLAKQTEIA YGTLEAGSTK EFFRRSKIAV FEKMWTYMKS AEPSVFVRTT EEGMIRVRKS KGKYAYLLES TMNEYIEQRK PCDTMKVGGN LDSKGYGIAT PKGSALRNPV NLAVLKLNEQ GLLDKLKNKW WYDKGECGSG GGDSKDKTSA LSLSNVAGVF YILIGGLGLA MLVALIEFCY KSRSESKRMK GFCLIPQQSI NEAIRTSTLP RNSGAGASSG GSGENGRVVS HDFPKSMQSI PCMSHSSGMP LGATGL
Genular Protein ID: 938772174
Symbol: Q59GL5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 833
- Mass: 93291
- Checksum: BDBA6AF7FEC49566
- Sequence:
ICSQFSKGVY AIFGFYERRT VNMLTSFCGA LHVCFITPSF PVDTSNQFVL QLRPELQDAL ISIIDHYKWQ KFVYIYDADR GLSVLQKVLD TAAEKNWQVT AVNILTTTEE GYRMLFQDLE KKKERLVVVD CESERLNAIL GQIIKLEKNG IGYHYILANL GFMDIDLNKF KESGANVTGF QLVNYTDTIP AKIMQQWKNS DARDHTRVDW KRPKYTSALT YDGVKVMAEA FQSLRRQRID ISRRGNAGDC LANPAVPWGQ GIDIQRALQQ VRFEGLTGNV QFNEKGRRTN YTLHVIEMKH DGIRKIGYWN EDDKFVPAAT DAQAGGDNSS VQNRTYIVTT ILEDPYVMLK KNANQFEGND RYEGYCVELA AEIAKHVGYS YRLEIVSDGK YGARDPDTKA WNGMVGELVY GRADVAVAPL TITLVREEVI DFSKPFMSLG ISIMIKKPQK SKPGVFSFLD PLAYEIWMCI VFAYIGVSVV LFLVSRFSPY EWHSEEFEEG RDQTTSDQSN EFGIFNSLWF SLGAFMQQGC DISPRSLSGR IVGGVWWFFT LIIISSYTAN LAAFLTVERM VSPIESAEDL AKQTEIAYGT LEAGSTKEFF RRSKIAVFEK MWTYMKSAEP SVFVRTTEEG MIRVRKSKGK YAYLLESTMN EYIEQRKPCD TMKVGGNLDS KGYGIATPKG SALRGPVNLA VLKLSEQGVL DKLKSKWWYD KGECGSKDSG SKDKTSALSL SNVAGVFYIL IGGLGLAMLV ALIEFCYKSR SESKRMKGFC LIPQQSINEA IRTSTLPRNS GAGASSGGSG ENGRVVSHDF PKSMQSIPCM SHSSGMPLGA TGL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.