Details for: ATAD2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 99.3915
Cell Significance Index: -25.2100 - Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 98.3315
Cell Significance Index: -15.3000 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 60.6198
Cell Significance Index: -28.6200 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 56.1713
Cell Significance Index: -22.8200 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 24.1112
Cell Significance Index: -23.0200 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 21.3430
Cell Significance Index: -26.3200 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 10.1797
Cell Significance Index: -27.2700 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 7.0846
Cell Significance Index: -21.7600 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 6.9411
Cell Significance Index: -27.3900 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 4.1534
Cell Significance Index: -9.0900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.4589
Cell Significance Index: 487.9800 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 2.0732
Cell Significance Index: 205.0900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.0000
Cell Significance Index: 112.2300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.4721
Cell Significance Index: 112.9700 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 1.2864
Cell Significance Index: 34.4100 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.1786
Cell Significance Index: 16.0800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.1014
Cell Significance Index: 30.7800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.0011
Cell Significance Index: 200.8100 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.9629
Cell Significance Index: 104.7400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.9358
Cell Significance Index: 56.1800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.9195
Cell Significance Index: 108.4400 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.5272
Cell Significance Index: 8.8800 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.4787
Cell Significance Index: 10.3700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.4748
Cell Significance Index: 170.2900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.4716
Cell Significance Index: 425.8000 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.4332
Cell Significance Index: 11.7900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.4298
Cell Significance Index: 19.0100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.4234
Cell Significance Index: 52.0700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.4130
Cell Significance Index: 15.6400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.4128
Cell Significance Index: 11.9000 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.3593
Cell Significance Index: 64.7700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.3168
Cell Significance Index: 8.4600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2911
Cell Significance Index: 55.4000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.2826
Cell Significance Index: 12.8100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.2603
Cell Significance Index: 16.8000 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.2480
Cell Significance Index: 12.8900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1907
Cell Significance Index: 84.3000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.1897
Cell Significance Index: 103.6000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1694
Cell Significance Index: 23.2700 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1368
Cell Significance Index: 94.6000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1224
Cell Significance Index: 3.0600 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.0948
Cell Significance Index: 1.4000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0861
Cell Significance Index: 53.7800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0803
Cell Significance Index: 5.5500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0646
Cell Significance Index: 121.5800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.0428
Cell Significance Index: 2.2300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0359
Cell Significance Index: 1.2600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0304
Cell Significance Index: 19.2900 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0256
Cell Significance Index: 0.6800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0152
Cell Significance Index: 23.3900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0113
Cell Significance Index: 15.3200 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0053
Cell Significance Index: 9.7600 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0046
Cell Significance Index: 0.3300 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0076
Cell Significance Index: -0.9800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0089
Cell Significance Index: -0.1900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0135
Cell Significance Index: -6.1400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0156
Cell Significance Index: -11.5300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0276
Cell Significance Index: -15.5400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0321
Cell Significance Index: -24.2900 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0334
Cell Significance Index: -24.5000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0345
Cell Significance Index: -5.0200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0422
Cell Significance Index: -2.8400 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0493
Cell Significance Index: -8.4200 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0543
Cell Significance Index: -6.3300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0639
Cell Significance Index: -3.9300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0719
Cell Significance Index: -15.1400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0724
Cell Significance Index: -20.8400 - Cell Name: germ cell (CL0000586)
Fold Change: -0.0755
Cell Significance Index: -0.5700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1029
Cell Significance Index: -4.8000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1091
Cell Significance Index: -3.5000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1100
Cell Significance Index: -11.2400 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1101
Cell Significance Index: -14.2200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1138
Cell Significance Index: -13.0400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1372
Cell Significance Index: -6.4500 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.1491
Cell Significance Index: -17.0200 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1673
Cell Significance Index: -5.8200 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1730
Cell Significance Index: -4.4200 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.1751
Cell Significance Index: -5.0200 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.2014
Cell Significance Index: -3.3700 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.2195
Cell Significance Index: -3.2400 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2234
Cell Significance Index: -16.6500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2386
Cell Significance Index: -24.8400 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2854
Cell Significance Index: -5.5700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.3163
Cell Significance Index: -5.4200 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.3192
Cell Significance Index: -4.8100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3223
Cell Significance Index: -25.5300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.3350
Cell Significance Index: -20.5400 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: -0.3351
Cell Significance Index: -3.3800 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.4223
Cell Significance Index: -8.8400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.4311
Cell Significance Index: -27.1700 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.4433
Cell Significance Index: -14.1200 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.4470
Cell Significance Index: -4.8600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.4637
Cell Significance Index: -15.1800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.4847
Cell Significance Index: -25.4500 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.5190
Cell Significance Index: -14.8100 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.5312
Cell Significance Index: -12.7400 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.5352
Cell Significance Index: -18.7500 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.5481
Cell Significance Index: -11.3700 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.5574
Cell Significance Index: -16.3700 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.5636
Cell Significance Index: -8.7200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2028015105
Symbol: ATAD2_HUMAN
Name: ATPase family AAA domain-containing protein 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15334068
Title: Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer.
PubMed ID: 15334068
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 11483580
Title: Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs.
PubMed ID: 11483580
DOI: 10.1101/gr.175501
PubMed ID: 15721472
Title: Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer.
PubMed ID: 15721472
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 17076897
Title: A consensus prognostic gene expression classifier for ER positive breast cancer.
PubMed ID: 17076897
PubMed ID: 16709241
Title: Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery.
PubMed ID: 16709241
PubMed ID: 17660802
Title: Prognostic significance of drug-regulated genes in high-grade osteosarcoma.
PubMed ID: 17660802
PubMed ID: 17998543
Title: ANCCA, an estrogen-regulated AAA+ ATPase coactivator for ERalpha, is required for coregulator occupancy and chromatin modification.
PubMed ID: 17998543
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25593309
Title: Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.
PubMed ID: 25593309
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 22464331
Title: Histone recognition and large-scale structural analysis of the human bromodomain family.
PubMed ID: 22464331
Sequence Information:
- Length: 1390
- Mass: 158554
- Checksum: F43B30C77BB0F4BA
- Sequence:
MVVLRSSLEL HNHSAASATG SLDLSSDFLS LEHIGRRRLR SAGAAQKKPA ATTAKAGDGS SVKEVETYHR TRALRSLRKD AQNSSDSSFE KNVEITEQLA NGRHFTRQLA RQQADKKKEE HREDKVIPVT RSLRARNIVQ STEHLHEDNG DVEVRRSCRI RSRYSGVNQS MLFDKLITNT AEAVLQKMDD MKKMRRQRMR ELEDLGVFNE TEESNLNMYT RGKQKDIQRT DEETTDNQEG SVESSEEGED QEHEDDGEDE DDEDDDDDDD DDDDDDDEDD EDEEDGEEEN QKRYYLRQRK ATVYYQAPLE KPRHQRKPNI FYSGPASPAR PRYRLSSAGP RSPYCKRMNR RRHAIHSSDS TSSSSSEDEQ HFERRRKRSR NRAINRCLPL NFRKDELKGI YKDRMKIGAS LADVDPMQLD SSVRFDSVGG LSNHIAALKE MVVFPLLYPE VFEKFKIQPP RGCLFYGPPG TGKTLVARAL ANECSQGDKR VAFFMRKGAD CLSKWVGESE RQLRLLFDQA YQMRPSIIFF DEIDGLAPVR SSRQDQIHSS IVSTLLALMD GLDSRGEIVV IGATNRLDSI DPALRRPGRF DREFLFSLPD KEARKEILKI HTRDWNPKPL DTFLEELAEN CVGYCGADIK SICAEAALCA LRRRYPQIYT TSEKLQLDLS SINISAKDFE VAMQKMIPAS QRAVTSPGQA LSTVVKPLLQ NTVDKILEAL QRVFPHAEFR TNKTLDSDIS CPLLESDLAY SDDDVPSVYE NGLSQKSSHK AKDNFNFLHL NRNACYQPMS FRPRILIVGE PGFGQGSHLA PAVIHALEKF TVYTLDIPVL FGVSTTSPEE TCAQVIREAK RTAPSIVYVP HIHVWWEIVG PTLKATFTTL LQNIPSFAPV LLLATSDKPH SALPEEVQEL FIRDYGEIFN VQLPDKEERT KFFEDLILKQ AAKPPISKKK AVLQALEVLP VAPPPEPRSL TAEEVKRLEE QEEDTFRELR IFLRNVTHRL AIDKRFRVFT KPVDPDEVPD YVTVIKQPMD LSSVISKIDL HKYLTVKDYL RDIDLICSNA LEYNPDRDPG DRLIRHRACA LRDTAYAIIK EELDEDFEQL CEEIQESRKK RGCSSSKYAP SYYHVMPKQN STLVGDKRSD PEQNEKLKTP STPVACSTPA QLKRKIRKKS NWYLGTIKKR RKISQAKDDS QNAIDHKIES DTEETQDTSV DHNETGNTGE SSVEENEKQQ NASESKLELR NNSNTCNIEN ELEDSRKTTA CTELRDKIAC NGDASSSQII HISDENEGKE MCVLRMTRAR RSQVEQQQLI TVEKALAILS QPTPSLVVDH ERLKNLLKTV VKKSQNYNIF QLENLYAVIS QCIYRHRKDH DKTSLIQKME QEVENFSCSR
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.