Details for: FHOD1

Gene ID: 29109

Symbol: FHOD1

Ensembl ID: ENSG00000135723

Description: formin homology 2 domain containing 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 64.1935
    Cell Significance Index: -9.9900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 34.9309
    Cell Significance Index: -8.8600
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 25.8043
    Cell Significance Index: -10.6300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 25.4519
    Cell Significance Index: -10.3400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 11.1287
    Cell Significance Index: -10.6300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 8.6864
    Cell Significance Index: -10.7100
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 6.5156
    Cell Significance Index: 40.3100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 3.6433
    Cell Significance Index: -9.7600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 2.8130
    Cell Significance Index: -8.6400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.7217
    Cell Significance Index: -10.7400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 2.3348
    Cell Significance Index: -5.1100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.4424
    Cell Significance Index: 75.1300
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.8533
    Cell Significance Index: 20.8200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.7513
    Cell Significance Index: 20.1300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.7064
    Cell Significance Index: 32.0200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6933
    Cell Significance Index: 625.9600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5776
    Cell Significance Index: 93.9400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.4960
    Cell Significance Index: 12.7500
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: 0.4698
    Cell Significance Index: 7.5800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.4269
    Cell Significance Index: 7.8900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.3764
    Cell Significance Index: 28.8900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3443
    Cell Significance Index: 9.9200
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.3151
    Cell Significance Index: 4.5200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2404
    Cell Significance Index: 16.6300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.2340
    Cell Significance Index: 27.2700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.2275
    Cell Significance Index: 6.6800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2247
    Cell Significance Index: 42.7700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1800
    Cell Significance Index: 3.9000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1593
    Cell Significance Index: 15.7600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1472
    Cell Significance Index: 29.2100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1334
    Cell Significance Index: 15.7300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1326
    Cell Significance Index: 18.2100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.1272
    Cell Significance Index: 3.2500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1167
    Cell Significance Index: 14.9600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1077
    Cell Significance Index: 6.9500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.1046
    Cell Significance Index: 1.7500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0849
    Cell Significance Index: 58.6900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0839
    Cell Significance Index: 16.8400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0678
    Cell Significance Index: 12.2300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0664
    Cell Significance Index: 3.1200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0593
    Cell Significance Index: 2.7700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0541
    Cell Significance Index: 1.9000
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.0508
    Cell Significance Index: 1.0900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0481
    Cell Significance Index: 26.2500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0396
    Cell Significance Index: 0.9900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0365
    Cell Significance Index: 5.3000
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.0281
    Cell Significance Index: 0.1700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0272
    Cell Significance Index: 12.0400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0220
    Cell Significance Index: 7.9000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0167
    Cell Significance Index: 2.1600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0148
    Cell Significance Index: 0.3900
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.0129
    Cell Significance Index: 0.1100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0089
    Cell Significance Index: 1.1000
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.0078
    Cell Significance Index: 0.1000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0061
    Cell Significance Index: 11.5500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0036
    Cell Significance Index: 5.5700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0031
    Cell Significance Index: 2.3800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0016
    Cell Significance Index: 3.0200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0019
    Cell Significance Index: -0.1000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0029
    Cell Significance Index: -1.8500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0041
    Cell Significance Index: -5.5800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0089
    Cell Significance Index: -0.6600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0106
    Cell Significance Index: -7.7900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0157
    Cell Significance Index: -7.1200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0159
    Cell Significance Index: -11.7900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0197
    Cell Significance Index: -3.3600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0199
    Cell Significance Index: -12.4000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0202
    Cell Significance Index: -11.3900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0223
    Cell Significance Index: -0.7200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0238
    Cell Significance Index: -2.4300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0315
    Cell Significance Index: -0.4300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0320
    Cell Significance Index: -9.2100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0427
    Cell Significance Index: -0.9100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0541
    Cell Significance Index: -6.2000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0551
    Cell Significance Index: -3.0900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0577
    Cell Significance Index: -12.1600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0694
    Cell Significance Index: -2.4100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0700
    Cell Significance Index: -1.8700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0707
    Cell Significance Index: -1.8900
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0711
    Cell Significance Index: -1.1400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0754
    Cell Significance Index: -5.3300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0769
    Cell Significance Index: -1.6100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0935
    Cell Significance Index: -9.7400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0988
    Cell Significance Index: -4.3700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1048
    Cell Significance Index: -2.9300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1114
    Cell Significance Index: -5.8500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1176
    Cell Significance Index: -3.3700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1219
    Cell Significance Index: -7.4800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1304
    Cell Significance Index: -3.5500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1309
    Cell Significance Index: -6.6200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1390
    Cell Significance Index: -11.0100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1438
    Cell Significance Index: -5.4500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1441
    Cell Significance Index: -8.8600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1462
    Cell Significance Index: -9.8300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1506
    Cell Significance Index: -9.4900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1515
    Cell Significance Index: -2.1700
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.1553
    Cell Significance Index: -1.3200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1582
    Cell Significance Index: -3.4700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1876
    Cell Significance Index: -2.7700
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.1891
    Cell Significance Index: -2.7200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** FHOD1 is a member of the formin family of proteins, which are known for their role in actin filament assembly and organization. The FHOD1 protein contains a unique combination of formin homology 2 (FH2) domains, which are essential for its activity. These domains enable FHOD1 to interact with actin filaments and regulate their assembly and disassembly. The protein's ability to bind actin filaments and regulate their dynamics is crucial for maintaining the structural integrity of cells and tissues. **Pathways and Functions:** FHOD1 is involved in several key cellular pathways, including: 1. **Actin filament binding:** FHOD1's interaction with actin filaments is essential for its function. The protein's ability to bind actin filaments and regulate their assembly and disassembly is crucial for maintaining cellular homeostasis. 2. **Cortical actin cytoskeleton organization:** FHOD1 plays a critical role in the organization of the cortical actin cytoskeleton, which is essential for maintaining cell shape and integrity. 3. **Establishment of centrosome localization:** FHOD1 is involved in the establishment of centrosome localization, which is critical for maintaining proper cell division and migration. 4. **Nuclear migration:** FHOD1's ability to regulate nuclear migration is essential for maintaining proper cell-cell interactions and tissue organization. 5. **Positive regulation of stress fiber assembly:** FHOD1's interaction with actin filaments and regulation of their assembly and disassembly is essential for maintaining cellular homeostasis. **Clinical Significance:** Dysregulation of FHOD1 has been implicated in various disease states, including: 1. **Cardiovascular disease:** FHOD1's role in regulating actin filament assembly and disassembly is critical for maintaining cardiac muscle function. Dysregulation of FHOD1 has been implicated in cardiac hypertrophy and failure. 2. **Neurological disorders:** FHOD1's involvement in nuclear migration and stress fiber assembly makes it a potential target for the treatment of neurological disorders, such as Alzheimer's disease and Parkinson's disease. 3. **Cancer:** FHOD1's role in regulating actin filament assembly and disassembly makes it a potential target for the treatment of cancer. In conclusion, FHOD1 is a complex gene that plays a critical role in maintaining cellular homeostasis and regulating actin filament assembly and disassembly. Its dysregulation has been implicated in various disease states, highlighting the need for further research into its mechanisms of action and potential therapeutic applications.

Genular Protein ID: 2426559126

Symbol: FHOD1_HUMAN

Name: FH1/FH2 domain-containing protein 1

UniProtKB Accession Codes:

Q9Y613 Q59F76 Q6Y1F2 Q76MS8 Q8N521

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 5 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 16 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10352228

Title: Identification and characterization of a protein containing formin homology (FH1/FH2) domains.

PubMed ID: 10352228

DOI: 10.1016/s0378-1119(99)00127-4

PubMed ID: 14576350

Title: Fhos, a mammalian formin, directly binds to F-actin via a region N-terminal to the FH1 domain and forms a homotypic complex via the FH2 domain to promote actin fiber formation.

PubMed ID: 14576350

DOI: 10.1242/jcs.00769

PubMed ID: 15138285

Title: EBV attachment stimulates FHOS/FHOD1 redistribution and co-aggregation with CD21: formin interactions with the cytoplasmic domain of human CD21.

PubMed ID: 15138285

DOI: 10.1242/jcs.01113

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 15878344

Title: FHOD1 coordinates actin filament and microtubule alignment to mediate cell elongation.

PubMed ID: 15878344

DOI: 10.1016/j.yexcr.2005.02.006

PubMed ID: 16361249

Title: Biochemical characterization of the diaphanous autoregulatory interaction in the formin homology protein FHOD1.

PubMed ID: 16361249

DOI: 10.1074/jbc.m509226200

PubMed ID: 18694941

Title: The diaphanous-related formin FHOD1 associates with ROCK1 and promotes Src-dependent plasma membrane blebbing.

PubMed ID: 18694941

DOI: 10.1074/jbc.m801800200

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

Sequence Information:

  • Length: 1164
  • Mass: 126551
  • Checksum: E6C7AE1FB8DC3FC7
  • Sequence:
    • MAGGEDRGDG EPVSVVTVRV QYLEDTDPFA CANFPEPRRA PTCSLDGALP LGAQIPAVHR 
LLGAPLKLED CALQVSPSGY YLDTELSLEE QREMLEGFYE EISKGRKPTL ILRTQLSVRV 
NAILEKLYSS SGPELRRSLF SLKQIFQEDK DLVPEFVHSE GLSCLIRVGA AADHNYQSYI 
LRALGQLMLF VDGMLGVVAH SDTIQWLYTL CASLSRLVVK TALKLLLVFV EYSENNAPLF 
IRAVNSVAST TGAPPWANLV SILEEKNGAD PELLVYTVTL INKTLAALPD QDSFYDVTDA 
LEQQGMEALV QRHLGTAGTD VDLRTQLVLY ENALKLEDGD IEEAPGAGGR RERRKPSSEE 
GKRSRRSLEG GGCPARAPEP GPTGPASPVG PTSSTGPALL TGPASSPVGP PSGLQASVNL 
FPTISVAPSA DTSSERSIYK ARFLENVAAA ETEKQVALAQ GRAETLAGAM PNEAGGHPDA 
RQLWDSPETA PAARTPQSPA PCVLLRAQRS LAPEPKEPLI PASPKAEPIW ELPTRAPRLS 
IGDLDFSDLG EDEDQDMLNV ESVEAGKDIP APSPPLPLLS GVPPPPPLPP PPPIKGPFPP 
PPPLPLAAPL PHSVPDSSAL PTKRKTVKLF WRELKLAGGH GVSASRFGPC ATLWASLDPV 
SVDTARLEHL FESRAKEVLP SKKAGEGRRT MTTVLDPKRS NAINIGLTTL PPVHVIKAAL 
LNFDEFAVSK DGIEKLLTMM PTEEERQKIE EAQLANPDIP LGPAENFLMT LASIGGLAAR 
LQLWAFKLDY DSMEREIAEP LFDLKVGMEQ LVQNATFRCI LATLLAVGNF LNGSQSSGFE 
LSYLEKVSEV KDTVRRQSLL HHLCSLVLQT RPESSDLYSE IPALTRCAKV DFEQLTENLG 
QLERRSRAAE ESLRSLAKHE LAPALRARLT HFLDQCARRV AMLRIVHRRV CNRFHAFLLY 
LGYTPQAARE VRIMQFCHTL REFALEYRTC RERVLQQQQK QATYRERNKT RGRMITETEK 
FSGVAGEAPS NPSVPVAVSS GPGRGDADSH ASMKSLLTSR PEDTTHNRRS RGMVQSSSPI 
MPTVGPSTAS PEEPPGSSLP SDTSDEIMDL LVQSVTKSSP RALAARERKR SRGNRKSLRR 
TLKSGLGDDL VQALGLSKGP GLEV

Genular Protein ID: 1497223851

Symbol: A0A068F7M9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A068F7M9

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Gene3D 2 IntAct 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 2 SMART 1 SUPFAM 2

Sequence Information:

  • Length: 1190
  • Mass: 129313
  • Checksum: 11338D800F7846E4
  • Sequence:
    • MAGGEDRGDG EPVSVVTVRV QYLEDTDPFA CANFPEPRRA PTCSLDGALP LGAQIPAVHR 
LLGAPLKLED CALQVSPSGY YLDTELSLEE QREMLEGFYE EISKGRKPTL ILRTQLSVRV 
NAILEKLYSS SGPELRRSLF SLKQIFQEDK DLVPEFVHSE GLSCLIRVGA AADHNYQSYI 
LRALGQLMLF VDGMLGVVAH SDTIQWLYTL CASLSRLVVK TALKLLLVFV EYSENNAPLF 
IRAVNSVAST TGAPPWANLV SILEEKNGAD PELLVYTVTL INKTLAALPD QDSFYDVTDA 
LEQQGMEALV QRHLGTAGTD VDLRTQLVLY ENALKLEDGD IEEAPGAGGR RERRKPSSEE 
GKRSRRSLEG GGCPARAPEP GPTGPASPVG PTSSTGPALL TGPASSPVGP PSGLQASVNL 
FPTISVAPSA DTSSERSIYK LHQTASVWAP ESPPVPQSPP GQARLEARFL ENVAAAETEK 
QVALAQGRAE TLAGAMPNEA GGHPDARQLW DSPETAPAAR TPQSPAPCVL LRAQRSLAPE 
PKEPLIPASP KAEPIWELPT RAPRLSIGDL DFSDLGEDED QDMLNVESVE AGKDIPAPSP 
PLPLLSGVPP PPPLPPPPPI KGPFPPPPPL PLAAPLPHSV PDSSALPTKR KTVKLFWREL 
KLAGGHGVSA SRFGPCATLW ASLDPVSVDT ARLEHLFESR AKEVLPSKKA GEGRRTMTTV 
LDPKRSNAIN IGLTTLPPVH VIKAALLNFD EFAVSKDGIE KLLTMMPTEE ERQKIEEAQL 
ANPDIPLGPA ENFLMTLASI GGLAARLQLW AFKLDYDSME REIAEPLFDL KVGMEQLVQN 
ATFRCILATL LAVGNFLNGS QSSGFELSYL EKVSEVKDTV RRQSLLHHLC SLVLQTRPES 
SDLYSEIPAL TRCAKVDFEQ LTENLGQLER RSRAAEESLR SLAKHELAPA LRARLTHFLD 
QCARRVAMLR IVHRRVCNRF HAFLLYLGYT PQAAREVRIM QFCHTLREFA LEYRTCRERV 
LQQQQKQATY RERNKTRGRM ITETEKFSGV AGEAPSNPSV PVAVSSGPGR GDADSHASMK 
SLLTSRPEDT THNRRSRGMV QSSSPIMPTV GPSTASPEEP PGSSLPSDTS DEIMDLLVQS 
VTKSSPRALA ARERKRSRGN RKSLRRTLKS GLGDDLVQAL GLSKGPGLEV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.