Details for: ANKRD11
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 687.1956
Cell Significance Index: -106.8900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 410.0245
Cell Significance Index: -104.0000 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 244.5975
Cell Significance Index: -115.4800 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 226.4083
Cell Significance Index: -91.9800 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 210.0371
Cell Significance Index: -108.0400 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 172.1106
Cell Significance Index: -115.4900 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 96.8533
Cell Significance Index: -92.4700 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 91.0414
Cell Significance Index: -112.2500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 40.3941
Cell Significance Index: -108.2100 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 30.9495
Cell Significance Index: -95.0600 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 28.6819
Cell Significance Index: -113.1800 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 26.4371
Cell Significance Index: -57.8600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 4.0531
Cell Significance Index: 113.2700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 3.6792
Cell Significance Index: 206.4600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 3.0364
Cell Significance Index: 602.5800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 2.9119
Cell Significance Index: 187.8600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 2.7880
Cell Significance Index: 342.8100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.6637
Cell Significance Index: 534.3300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 2.3564
Cell Significance Index: 424.7800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.3067
Cell Significance Index: 827.3800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 2.1967
Cell Significance Index: 168.5800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.0322
Cell Significance Index: 279.0800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.7524
Cell Significance Index: 79.4300 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 1.6712
Cell Significance Index: 87.0500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 1.6432
Cell Significance Index: 110.4900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.5236
Cell Significance Index: 1053.7600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.4813
Cell Significance Index: 808.9800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.2258
Cell Significance Index: 199.3600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.1903
Cell Significance Index: 2241.1200 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 1.1021
Cell Significance Index: 29.4800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 1.0947
Cell Significance Index: 48.4200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.0866
Cell Significance Index: 23.5400 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.0114
Cell Significance Index: 27.5300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.9884
Cell Significance Index: 60.7500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.9329
Cell Significance Index: 43.8500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.9272
Cell Significance Index: 26.7200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.8572
Cell Significance Index: 32.4600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.6866
Cell Significance Index: 303.5600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.5818
Cell Significance Index: 14.9600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.5207
Cell Significance Index: 27.0500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.4820
Cell Significance Index: 306.0900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.4724
Cell Significance Index: 426.5600 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.3744
Cell Significance Index: 48.0000 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.3657
Cell Significance Index: 6.1600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.3232
Cell Significance Index: 146.7000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.2653
Cell Significance Index: 489.2300 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.2451
Cell Significance Index: 24.2500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.2404
Cell Significance Index: 370.0900 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.2163
Cell Significance Index: 6.2000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1841
Cell Significance Index: 31.4400 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.1839
Cell Significance Index: 3.5900 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.1624
Cell Significance Index: 17.6700 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1604
Cell Significance Index: 5.6400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0834
Cell Significance Index: 113.4000 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.0323
Cell Significance Index: 0.4700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0082
Cell Significance Index: 0.2200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0067
Cell Significance Index: -4.8900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0259
Cell Significance Index: -16.2000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0495
Cell Significance Index: -7.2000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0602
Cell Significance Index: -44.6000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0746
Cell Significance Index: -56.5000 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0774
Cell Significance Index: -10.0000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: -0.1149
Cell Significance Index: -21.8600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1487
Cell Significance Index: -83.8500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1938
Cell Significance Index: -22.8500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.2325
Cell Significance Index: -16.4400 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.2768
Cell Significance Index: -28.2800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2815
Cell Significance Index: -59.3000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.2913
Cell Significance Index: -13.5800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.3340
Cell Significance Index: -96.0900 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.4072
Cell Significance Index: -11.6200 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.5360
Cell Significance Index: -8.9700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.5437
Cell Significance Index: -63.3600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.5735
Cell Significance Index: -42.7400 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.5782
Cell Significance Index: -66.0000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.5836
Cell Significance Index: -66.8700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.5853
Cell Significance Index: -10.0300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.5913
Cell Significance Index: -61.5700 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.7413
Cell Significance Index: -25.7600 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.7460
Cell Significance Index: -17.8900 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.7900
Cell Significance Index: -7.2800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.8323
Cell Significance Index: -52.4600 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.9230
Cell Significance Index: -24.2700 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.9887
Cell Significance Index: -13.4900 - Cell Name: peg cell (CL4033014)
Fold Change: -1.0176
Cell Significance Index: -23.5100 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -1.0201
Cell Significance Index: -15.0600 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -1.0245
Cell Significance Index: -6.1900 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -1.1050
Cell Significance Index: -29.6100 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -1.1179
Cell Significance Index: -16.7500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -1.1703
Cell Significance Index: -92.6900 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -1.2456
Cell Significance Index: -18.3900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -1.2491
Cell Significance Index: -65.5800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.5419
Cell Significance Index: -94.5400 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -1.6274
Cell Significance Index: -23.3700 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -1.6291
Cell Significance Index: -39.7500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -1.7541
Cell Significance Index: -56.1800 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -1.9611
Cell Significance Index: -41.9200 - Cell Name: decidual cell (CL2000002)
Fold Change: -2.0619
Cell Significance Index: -33.0800 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -2.1062
Cell Significance Index: -67.0800 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -2.1539
Cell Significance Index: -70.5200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2061939468
Symbol: ANR11_HUMAN
Name: Ankyrin repeat domain-containing protein 11
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15184363
Title: Identification of a novel family of ankyrin repeats-containing cofactors for p160 nuclear receptor coactivators.
PubMed ID: 15184363
PubMed ID: 15616553
Title: The sequence and analysis of duplication-rich human chromosome 16.
PubMed ID: 15616553
DOI: 10.1038/nature03187
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21782149
Title: Mutations in ANKRD11 cause KBG syndrome, characterized by intellectual disability, skeletal malformations, and macrodontia.
PubMed ID: 21782149
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25556659
Title: Ankrd11 is a chromatin regulator involved in autism that is essential for neural development.
PubMed ID: 25556659
PubMed ID: 25413698
Title: Characterization of ANKRD11 mutations in humans and mice related to KBG syndrome.
PubMed ID: 25413698
Sequence Information:
- Length: 2663
- Mass: 297913
- Checksum: 845B04094AF37CFE
- Sequence:
MPKGGCPKAP QQEELPLSSD MVEKQTGKKD KDKVSLTKTP KLERGDGGKE VRERASKRKL PFTAGANGEQ KDSDTEKQGP ERKRIKKEPV TRKAGLLFGM GLSGIRAGYP LSERQQVALL MQMTAEESAN SPVDTTPKHP SQSTVCQKGT PNSASKTKDK VNKRNERGET RLHRAAIRGD ARRIKELISE GADVNVKDFA GWTALHEACN RGYYDVAKQL LAAGAEVNTK GLDDDTPLHD AANNGHYKVV KLLLRYGGNP QQSNRKGETP LKVANSPTMV NLLLGKGTYT SSEESSTESS EEEDAPSFAP SSSVDGNNTD SEFEKGLKHK AKNPEPQKAT APVKDEYEFD EDDEQDRVPP VDDKHLLKKD YRKETKSNSF ISIPKMEVKS YTKNNTIAPK KASHRILSDT SDEEDASVTV GTGEKLRLSA HTILPGSKTR EPSNAKQQKE KNKVKKKRKK ETKGREVRFG KRSDKFCSSE SESESSESGE DDRDSLGSSG CLKGSPLVLK DPSLFSSLSA SSTSSHGSSA AQKQNPSHTD QHTKHWRTDN WKTISSPAWS EVSSLSDSTR TRLTSESDYS SEGSSVESLK PVRKRQEHRK RASLSEKKSP FLSSAEGAVP KLDKEGKVVK KHKTKHKHKN KEKGQCSISQ ELKLKSFTYE YEDSKQKSDK AILLENDLST ENKLKVLKHD RDHFKKEEKL SKMKLEEKEW LFKDEKSLKR IKDTNKDISR SFREEKDRSN KAEKERSLKE KSPKEEKLRL YKEERKKKSK DRPSKLEKKN DLKEDKISKE KEKIFKEDKE KLKKEKVYRE DSAFDEYCNK NQFLENEDTK FSLSDDQRDR WFSDLSDSSF DFKGEDSWDS PVTDYRDMKS DSVAKLILET VKEDSKERRR DSRAREKRDY REPFFRKKDR DYLDKNSEKR KEQTEKHKSV PGYLSEKDKK RRESAEAGRD RKDALESCKE RRDGRAKPEE AHREELKECG CESGFKDKSD GDFGKGLEPW ERHHPAREKE KKDGPDKERK EKTKPERYKE KSSDKDKSEK SILEKCQKDK EFDKCFKEKK DTKEKHKDTH GKDKERKASL DQGKEKKEKA FPGIISEDFS EKKDDKKGKE KSWYIADIFT DESEDDRDSC MGSGFKMGEA SDLPRTDGLQ EKEEGREAYA SDRHRKSSDK QHPERQKDKE PRDRRKDRGA ADAGRDKKEK VFEKHKEKKD KESTEKYKDR KDRASVDSTQ DKKNKQKLPE KAEKKHAAED KAKSKHKEKS DKEHSKERKS SRSADAEKSL LEKLEEEALH EYREDSNDKI SEVSSDSFTD RGQEPGLTAF LEVSFTEPPG DDKPRESACL PEKLKEKERH RHSSSSSKKS HDRERAKKEK AEKKEKGEDY KEGGSRKDSG QYEKDFLEAD AYGVSYNMKA DIEDELDKTI ELFSTEKKDK NDSEREPSKK IEKELKPYGS SAINILKEKK KREKHREKWR DEKERHRDRH ADGLLRHHRD ELLRHHRDEQ KPATRDKDSP PRVLKDKSRD EGPRLGDAKL KEKFKDGAEK EKGDPVKMSN GNDKVAPSKD PGKKDARPRE KLLGDGDLMM TSFERMLSQK DLEIEERHKR HKERMKQMEK LRHRSGDPKL KEKAKPADDG RKKGLDIPAK KPPGLDPPFK DKKLKESTPI PPAAENKLHP ASGADSKDWL AGPHMKEVLP ASPRPDQSRP TGVPTPTSVL SCPSYEEVMH TPRTPSCSAD DYADLVFDCA DSQHSTPVPT APTSACSPSF FDRFSVASSG LSENASQAPA RPLSTNLYRS VSVDIRRTPE EEFSVGDKLF RQQSVPAASS YDSPMPPSME DRAPLPPVPA EKFACLSPGY YSPDYGLPSP KVDALHCPPA AVVTVTPSPE GVFSSLQAKP SPSPRAELLV PSLEGALPPD LDTSEDQQAT AAIIPPEPSY LEPLDEGPFS AVITEEPVEW AHPSEQALAS SLIGGTSENP VSWPVGSDLL LKSPQRFPES PKRFCPADPL HSAAPGPFSA SEAPYPAPPA SPAPYALPVA EPGLEDVKDG VDAVPAAIST SEAAPYAPPS GLESFFSNCK SLPEAPLDVA PEPACVAAVA QVEALGPLEN SFLDGSRGLS HLGQVEPVPW ADAFAGPEDD LDLGPFSLPE LPLQTKDAAD GEAEPVEESL APPEEMPPGA PGVINGGDVS TVVAEEPPAL PPDQASTRLP AELEPEPSGE PKLDVALEAA VEAETVPEER ARGDPDSSVE PAPVPPEQRP LGSGDQGAEA EGPPAASLCA PDGPAPNTVA QAQAADGAGP EDDTEASRAA APAEGPPGGI QPEAAEPKPT AEAPKAPRVE EIPQRMTRNR AQMLANQSKQ GPPPSEKECA PTPAPVTRAK ARGSEDDDAQ AQHPRKRRFQ RSTQQLQQQL NTSTQQTREV IQQTLAAIVD AIKLDAIEPY HSDRANPYFE YLQIRKKIEE KRKILCCITP QAPQCYAEYV TYTGSYLLDG KPLSKLHIPV IAPPPSLAEP LKELFRQQEA VRGKLRLQHS IEREKLIVSC EQEILRVHCR AARTIANQAV PFSACTMLLD SEVYNMPLES QGDENKSVRD RFNARQFISW LQDVDDKYDR MKTCLLMRQQ HEAAALNAVQ RMEWQLKVQE LDPAGHKSLC VNEVPSFYVP MVDVNDDFVL LPA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.