Details for: RACGAP1

Gene ID: 29127

Symbol: RACGAP1

Ensembl ID: ENSG00000161800

Description: Rac GTPase activating protein 1

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 1.72
    Marker Score: 6,659
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.33
    Marker Score: 702
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 1.22
    Marker Score: 1,753
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 1.19
    Marker Score: 1,497
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 1.14
    Marker Score: 3,110
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 1.06
    Marker Score: 847
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.04
    Marker Score: 251,777
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 1.03
    Marker Score: 971
  • Cell Name: renal intercalated cell (CL0005010)
    Fold Change: 1.02
    Marker Score: 546
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,795
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,019
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.99
    Marker Score: 2,338
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,404
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.96
    Marker Score: 497
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.95
    Marker Score: 451
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,409
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,730
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.89
    Marker Score: 5,090
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 0.88
    Marker Score: 1,464
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.88
    Marker Score: 316
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,295
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 0.85
    Marker Score: 244
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.83
    Marker Score: 1,686
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.82
    Marker Score: 264
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 0.81
    Marker Score: 849
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.78
    Marker Score: 1,479
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 0.78
    Marker Score: 1,201
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1,259
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.77
    Marker Score: 11,998
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.76
    Marker Score: 577
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.75
    Marker Score: 386
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 0.74
    Marker Score: 795
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.74
    Marker Score: 296
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.74
    Marker Score: 501
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.73
    Marker Score: 2,155
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.7
    Marker Score: 638
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.68
    Marker Score: 174
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.68
    Marker Score: 509
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 0.68
    Marker Score: 337
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.67
    Marker Score: 2,819
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.67
    Marker Score: 196
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 0.67
    Marker Score: 886
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.64
    Marker Score: 2,663
  • Cell Name: oocyte (CL0000023)
    Fold Change: 0.63
    Marker Score: 155
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 0.62
    Marker Score: 2,582
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.61
    Marker Score: 366
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 0.6
    Marker Score: 375
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 0.57
    Marker Score: 20,982
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.55
    Marker Score: 442
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 0.55
    Marker Score: 309
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 0.55
    Marker Score: 4,692
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.54
    Marker Score: 33,373
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 0.54
    Marker Score: 5,101
  • Cell Name: promyelocyte (CL0000836)
    Fold Change: 0.53
    Marker Score: 263
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.52
    Marker Score: 2,045
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.5
    Marker Score: 157
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.5
    Marker Score: 500
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.5
    Marker Score: 361
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.49
    Marker Score: 833
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.48
    Marker Score: 581
  • Cell Name: fetal cardiomyocyte (CL0002495)
    Fold Change: 0.45
    Marker Score: 149
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.45
    Marker Score: 1,734
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 0.43
    Marker Score: 1,011
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.42
    Marker Score: 886
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 0.42
    Marker Score: 120
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.42
    Marker Score: 526
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.41
    Marker Score: 398
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 0.41
    Marker Score: 3,138
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.41
    Marker Score: 15,445
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.41
    Marker Score: 1,103
  • Cell Name: erythroid lineage cell (CL0000764)
    Fold Change: 0.4
    Marker Score: 200
  • Cell Name: neural cell (CL0002319)
    Fold Change: 0.4
    Marker Score: 192
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.39
    Marker Score: 124
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 0.39
    Marker Score: 3,662
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.39
    Marker Score: 262
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.39
    Marker Score: 184
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.38
    Marker Score: 102
  • Cell Name: glial cell (CL0000125)
    Fold Change: 0.37
    Marker Score: 407
  • Cell Name: pulmonary ionocyte (CL0017000)
    Fold Change: 0.36
    Marker Score: 224
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.36
    Marker Score: 413
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.36
    Marker Score: 2,185
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.36
    Marker Score: 94
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 0.36
    Marker Score: 226
  • Cell Name: neuron (CL0000540)
    Fold Change: 0.36
    Marker Score: 1,464
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: 0.36
    Marker Score: 206
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 0.35
    Marker Score: 1,471
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 0.35
    Marker Score: 7,010
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.35
    Marker Score: 144
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.34
    Marker Score: 307
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.33
    Marker Score: 148
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 0.33
    Marker Score: 123
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 0.33
    Marker Score: 237
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.33
    Marker Score: 220
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.33
    Marker Score: 164
  • Cell Name: early lymphoid progenitor (CL0000936)
    Fold Change: 0.33
    Marker Score: 160
  • Cell Name: interstitial cell of Cajal (CL0002088)
    Fold Change: 0.33
    Marker Score: 113
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.33
    Marker Score: 344
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 0.32
    Marker Score: 204
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.32
    Marker Score: 513
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.32
    Marker Score: 187

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RACGAP1 is a crucial regulator of Rac GTPases, which are essential for controlling cytoskeletal reorganization, cell migration, and cell cycle progression. The gene's expression is widespread, with significant levels found in cells involved in immune response, neural development, and tissue repair. RACGAP1's unique ability to interact with multiple signaling pathways, including those involving Rho GTPases, makes it an essential component of complex cellular processes. **Pathways and Functions:** RACGAP1 is involved in various signaling pathways, including: 1. **Immune System:** RACGAP1 regulates immune cell function, including antigen presentation, cytokine production, and cell migration. It interacts with MHC class II molecules and modulates the activity of immune cells, such as dendritic cells and T cells. 2. **Cytoskeletal Dynamics:** RACGAP1 controls cytoskeletal reorganization by regulating the activity of Rac GTPases, which are essential for cell migration, adhesion, and morphology. 3. **Cell Migration:** RACGAP1 is involved in cell migration, a process critical for immune cell trafficking, wound healing, and tissue repair. 4. **Cell Cycle Progression:** RACGAP1 regulates cell cycle progression by controlling the activity of Rac GTPases, which are essential for cell proliferation and differentiation. 5. **Signaling by Rho GTPases:** RACGAP1 interacts with Rho GTPases, modulating their activity and influencing cellular processes such as cell migration, adhesion, and morphology. **Clinical Significance:** RACGAP1's involvement in immune system regulation and cellular processes makes it a potential target for the treatment of various diseases, including: 1. **Immune Disorders:** RACGAP1's role in immune cell function and antigen presentation makes it a potential target for the treatment of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. 2. **Cancer:** RACGAP1's involvement in cell migration and proliferation makes it a potential target for the treatment of cancer, including metastatic disease. 3. **Neurological Disorders:** RACGAP1's role in neural development and function makes it a potential target for the treatment of neurological disorders, such as Parkinson's disease and Alzheimer's disease. In conclusion, RACGAP1 is a multifaceted gene that plays a critical role in regulating immune system function, cellular processes, and tissue development. Its involvement in multiple signaling pathways underscores its significance in maintaining cellular homeostasis and responding to environmental cues. Further research on RACGAP1's functions and clinical significance is necessary to fully understand its potential as a therapeutic target.

Genular Protein ID: 562419567

Symbol: RGAP1_HUMAN

Name: Rac GTPase-activating protein 1

UniProtKB Accession Codes:

Q9H0H5 Q6PJ26 Q9NWN2 Q9P250 Q9P2W2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 14 EPD 1 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 35 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 7 PIR 1 PRO 1 PROSITE 3 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 11 RefSeq 15 SAM 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10979956

Title: MgcRacGAP is involved in the control of growth and differentiation of hematopoietic cells.

PubMed ID: 10979956

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10819331

Title: Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10819331

DOI: 10.1093/dnares/7.2.143

PubMed ID: 9497316

Title: MgcRacGAP, a new human GTPase-activating protein for Rac and Cdc42 similar to Drosophila rotundRacGAP gene product, is expressed in male germ cells.

PubMed ID: 9497316

DOI: 10.1074/jbc.273.11.6019

PubMed ID: 11085985

Title: MgcRacGAP is involved in cytokinesis through associating with mitotic spindle and midbody.

PubMed ID: 11085985

DOI: 10.1074/jbc.m007252200

PubMed ID: 11278976

Title: Tat1, a novel sulfate transporter specifically expressed in human male germ cells and potentially linked to rhogtpase signaling.

PubMed ID: 11278976

DOI: 10.1074/jbc.m011740200

PubMed ID: 11782313

Title: Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity.

PubMed ID: 11782313

DOI: 10.1016/s1534-5807(01)00110-1

PubMed ID: 12590651

Title: Rho family GTPase Rnd2 interacts and co-localizes with MgcRacGAP in male germ cells.

PubMed ID: 12590651

DOI: 10.1042/bj20021652

PubMed ID: 12689593

Title: Phosphorylation by aurora B converts MgcRacGAP to a RhoGAP during cytokinesis.

PubMed ID: 12689593

DOI: 10.1016/s1534-5807(03)00089-3

PubMed ID: 14729465

Title: MgcRacGAP regulates cortical activity through RhoA during cytokinesis.

PubMed ID: 14729465

DOI: 10.1016/j.yexcr.2003.10.015

PubMed ID: 14744859

Title: Human mitotic spindle-associated protein PRC1 inhibits MgcRacGAP activity toward Cdc42 during the metaphase.

PubMed ID: 14744859

DOI: 10.1074/jbc.m313257200

PubMed ID: 16213214

Title: Centriolin anchoring of exocyst and SNARE complexes at the midbody is required for secretory-vesicle-mediated abscission.

PubMed ID: 16213214

DOI: 10.1016/j.cell.2005.07.027

PubMed ID: 15642749

Title: Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis.

PubMed ID: 15642749

DOI: 10.1083/jcb.200408085

PubMed ID: 16103226

Title: An ECT2-centralspindlin complex regulates the localization and function of RhoA.

PubMed ID: 16103226

DOI: 10.1083/jcb.200501097

PubMed ID: 16129829

Title: MgcRacGAP controls the assembly of the contractile ring and the initiation of cytokinesis.

PubMed ID: 16129829

DOI: 10.1073/pnas.0504145102

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16236794

Title: Dissecting the role of Rho-mediated signaling in contractile ring formation.

PubMed ID: 16236794

DOI: 10.1091/mbc.e05-06-0569

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18511905

Title: Sequential Cyk-4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis.

PubMed ID: 18511905

DOI: 10.1038/emboj.2008.112

PubMed ID: 18445686

Title: EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase.

PubMed ID: 18445686

DOI: 10.1242/jcs.019174

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19468302

Title: Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells.

PubMed ID: 19468302

DOI: 10.1371/journal.pbio.1000111

PubMed ID: 19468300

Title: Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation.

PubMed ID: 19468300

DOI: 10.1371/journal.pbio.1000110

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25068414

Title: Crystal structure of triple-BRCT-domain of ECT2 and insights into the binding characteristics to CYK-4.

PubMed ID: 25068414

DOI: 10.1016/j.febslet.2014.07.019

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 23235882

Title: Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis.

PubMed ID: 23235882

DOI: 10.1038/nature11773

PubMed ID: 34818416

Title: RACGAP1 variants in a sporadic case of CDA III implicate the dysfunction of centralspindlin as the basis of the disease.

PubMed ID: 34818416

DOI: 10.1182/blood.2021012334

Sequence Information:

  • Length: 632
  • Mass: 71027
  • Checksum: 032B7DF9CEA8F39D
  • Sequence:
    • MDTMMLNVRN LFEQLVRRVE ILSEGNEVQF IQLAKDFEDF RKKWQRTDHE LGKYKDLLMK 
AETERSALDV KLKHARNQVD VEIKRRQRAE ADCEKLERQI QLIREMLMCD TSGSIQLSEE 
QKSALAFLNR GQPSSSNAGN KRLSTIDESG SILSDISFDK TDESLDWDSS LVKTFKLKKR 
EKRRSTSRQF VDGPPGPVKK TRSIGSAVDQ GNESIVAKTT VTVPNDGGPI EAVSTIETVP 
YWTRSRRKTG TLQPWNSDST LNSRQLEPRT ETDSVGTPQS NGGMRLHDFV SKTVIKPESC 
VPCGKRIKFG KLSLKCRDCR VVSHPECRDR CPLPCIPTLI GTPVKIGEGM LADFVSQTSP 
MIPSIVVHCV NEIEQRGLTE TGLYRISGCD RTVKELKEKF LRVKTVPLLS KVDDIHAICS 
LLKDFLRNLK EPLLTFRLNR AFMEAAEITD EDNSIAAMYQ AVGELPQANR DTLAFLMIHL 
QRVAQSPHTK MDVANLAKVF GPTIVAHAVP NPDPVTMLQD IKRQPKVVER LLSLPLEYWS 
QFMMVEQENI DPLHVIENSN AFSTPQTPDI KVSLLGPVTT PEHQLLKTPS SSSLSQRVRS 
TLTKNTPRFG SKSKSATNLG RQGNFFASPM LK

Genular Protein ID: 1821382532

Symbol: B2RE34_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2RE34

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 2 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 632
  • Mass: 70968
  • Checksum: 92F87DFACFE39F61
  • Sequence:
    • MDTMMLNVRN LFEQLVRRVE ILSEGNEVQF IQLAKDFEDF RKKWQRTDHE LGKYKDLLMK 
AETERSALDV KLKHARNQVD VEIKRRQRAE ADCEKLERQI QLIREMLMCD TSGSIQLSEE 
QKSALAFLNR GQPSSSNAGN KRLSTIDESG SILSDISFDK TDESLDWDSS LVKTFKLKKR 
EKRRSTSRQF VDGPPGPVKK TRSIGSAVDQ GNESIVAKTT VTVPNDGGPI EAVSTIETVP 
YWTRSRRKTG TLQPWNSDST LNSRQLEPRT ETDSVGTPQS NGGMRLHDFV SKTVIKPESC 
VPCGKRIKFG KLSLKCRDCR VVSHPECRDR CPLPCIPTLI GTPVKIGEGM LADFVSQTSP 
MIPSIVVHCV NEIEQRGLTE TGLYRISGCD RTVKELKEKF LRVKTVPLLS KVDDIHAICS 
LLKDFLRNLK EPLLTFRLNR AFMEAAEITD EGNSIAAMYQ AVGELPQANR DTLAFLMIHL 
QRVAQSPHTK MDVANLAKVF GPTIVAHAVP NPDPVTMLQD IKRQPKVVER LLSLPLEYWS 
QFMMVEQENI DPLHVIENSN AFSTPQTPDI KVSLLGPVTT PEHQLLKTPS SSSLSQRVRS 
TLTKNTPRFG SKSKSATNLG RQGNFFASPM LK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.