Details for: OLA1
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 73.75rCSI 49.02%PRS 13.53
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CSI 60.49rCSI 54.63%PRS 10.03
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CSI 54.65rCSI 67.99%PRS 6.17
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CSI 46.99rCSI 78.87%PRS 6.67
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CSI 46.73rCSI 37.79%PRS 11.2
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CSI 44.99rCSI 47.02%PRS 11.99
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CSI 38rCSI 43.88%PRS 10.02
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CSI 37.97rCSI 67.06%PRS 6.64
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CSI 35.38rCSI 86%PRS 6.49
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CSI 35.13rCSI 41.96%PRS 6.53
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CSI 32.06rCSI 40.24%PRS 14.46
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CSI 31.28rCSI 50.3%PRS 7.41
-
CSI 29.8rCSI 65.84%PRS 8.15
-
CSI 27.42rCSI 31.39%PRS 23.31
-
CSI 27.36rCSI 85.51%PRS 7.15
-
CSI 27.34rCSI 26.37%PRS 7.69
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CSI 26.33rCSI 33.94%PRS 7.02
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CSI 26.23rCSI 30.81%PRS 13.46
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CSI 24.49rCSI 47.62%PRS 11.59
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CSI 23.73rCSI 63.19%PRS 9.18
-
CSI 23.14rCSI 72.38%PRS 7.7
-
CSI 23.13rCSI 83.24%PRS 6.15
-
CSI 22.72rCSI 35.11%PRS 10.66
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CSI 20.76rCSI 78.45%PRS 6.85
-
CSI 18.91rCSI 50.97%PRS 14.67
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CSI 18.11rCSI 62.02%PRS 10.49
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CSI 17.53rCSI 13.85%PRS 7.82
-
CSI 14.83rCSI 87.33%PRS 6.98
-
CSI 14.8rCSI 76.44%PRS 22.33
-
CSI 13.22rCSI 16.97%PRS 11.07
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CSI 12.91rCSI 11.34%PRS 12.74
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CSI 12.81rCSI 36.57%PRS 19.66
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CSI 12.53rCSI 27.18%PRS 6.03
-
CSI 11.98rCSI 48.35%PRS 10.39
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CSI 11.7rCSI 15.94%PRS 10.17
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CSI 11.27rCSI 16.65%PRS 17.88
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CSI 10.95rCSI 41.01%PRS 9.7
-
CSI 10.74rCSI 14.27%PRS 12.4
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CSI 10.73rCSI 7.23%PRS 13.59
-
CSI 10.68rCSI 78.49%PRS 5.69
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CSI 10.53rCSI 14.62%PRS 11.73
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CSI 9.75rCSI 17.45%PRS 10.63
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CSI 9.53rCSI 8.26%PRS 12.64
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CSI 9.46rCSI 9.1%PRS 11.75
-
CSI 9.36rCSI 46.52%PRS 12.75
-
CSI 7.79rCSI 18.64%PRS 6.21
-
CSI 7.75rCSI 14.08%PRS 9.38
-
CSI 7.58rCSI 51.59%PRS 11.78
-
CSI 7.43rCSI 40.07%PRS 21.41
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CSI 7.31rCSI 25.63%PRS 20.56
-
CSI 7.01rCSI 11.2%PRS 12.41
-
CSI 6.89rCSI 17.72%PRS 16.71
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CSI 6.68rCSI 8%PRS 19.48
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CSI 6.67rCSI 25.96%PRS 18.67
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CSI 6.64rCSI 11.65%PRS 8.2
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CSI 6.52rCSI 28.63%PRS 21.26
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CSI 6.49rCSI 19.16%PRS 14
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CSI 6.29rCSI 17.62%PRS 17.59
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CSI 6.21rCSI 5.15%PRS 10.72
-
CSI 6.12rCSI 5.13%PRS 13.61
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CSI 6.07rCSI 9.02%PRS 13.96
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CSI 5.96rCSI 46.7%PRS 25
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CSI 5.94rCSI 7.35%PRS 9.97
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CSI 5.88rCSI 39.03%PRS 11.96
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CSI 5.85rCSI 17.36%PRS 17.18
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CSI 5.84rCSI 50.29%PRS 3.34
-
CSI 5.8rCSI 4.51%PRS 16.35
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CSI 5.79rCSI 4.07%PRS 29.96
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CSI 5.52rCSI 36.25%PRS 29.5
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CSI 5.34rCSI 18.98%PRS 35.47
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CSI 5.25rCSI 13.64%PRS 15.44
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CSI 5.25rCSI 4.24%PRS 19.35
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CSI 5.2rCSI 15.06%PRS 12.87
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CSI 5.07rCSI 13.1%PRS 10.59
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CSI 5rCSI 7.65%PRS 18.48
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CSI 4.79rCSI 7.89%PRS 13.24
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CSI 4.68rCSI 29.95%PRS 17.79
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CSI 4.62rCSI 3.7%PRS 20.5
-
CSI 4.55rCSI 4.68%PRS 18.46
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CSI 4.5rCSI 63.91%PRS 7.91
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CSI 4.45rCSI 21.94%PRS 15.43
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CSI 4.44rCSI 3.95%PRS 11.37
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CSI 4.32rCSI 3.98%PRS 11.53
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CSI 4.19rCSI 24.75%PRS 12.46
-
CSI 4.06rCSI 8.94%PRS 17.43
-
CSI 4.01rCSI 2.79%PRS 16.12
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CSI 4rCSI 3.31%PRS 11.34
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CSI 3.95rCSI 30.64%PRS 11.81
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CSI 3.95rCSI 5.48%PRS 16.36
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CSI 3.94rCSI 9%PRS 10.06
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CSI 3.82rCSI 77.8%PRS 8.93
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CSI 3.8rCSI 8.31%PRS 15.22
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CSI 3.79rCSI 3.58%PRS 11.87
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CSI 3.76rCSI 3.94%PRS 10.58
-
CSI 3.76rCSI 89.95%PRS 5.11
-
CSI 3.74rCSI 76.2%PRS 9.79
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CSI 3.73rCSI 89.89%PRS 5.99
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CSI 3.64rCSI 5.86%PRS 8.74
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CSI 3.55rCSI 6.38%PRS 9.51
-
CSI 3.55rCSI 5.46%PRS 16.24
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CSI -14.1rCSI -17.7%PRS 17.4%
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CSI -7.6rCSI -18.9%PRS 33.9%
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CSI -5.1rCSI -14.7%PRS 16.4%
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CSI -3.8rCSI -3.5%PRS 20.7%
-
CSI -3.2rCSI -8.2%PRS 11.6%
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CSI -1.4rCSI -1.1%PRS 15.7%
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CSI -1.4rCSI -3.2%PRS 11.9%
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CSI -1.4rCSI -6.0%PRS 20.5%
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CSI -1.1rCSI -3.1%PRS 16.3%
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CSI -1.1rCSI -2.2%PRS 19.0%
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CSI -0.6rCSI -1.7%PRS 13.6%
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CSI -0.6rCSI -0.8%PRS 17.4%
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CSI -0.5rCSI -2.6%PRS 4.4%
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CSI -0.5rCSI -2.4%PRS 20.5%
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CSI -0.2rCSI -2.1%PRS 4.5%
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CSI 0.0rCSI 0.0%PRS 22.3%
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CSI 0.0rCSI 0.2%PRS 38.0%
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CSI 0.1rCSI 0.3%PRS 21.8%
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CSI 0.1rCSI 0.1%PRS 23.6%
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CSI 0.1rCSI 0.3%PRS 23.0%
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CSI 0.1rCSI 3.0%PRS 56.7%
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CSI 0.2rCSI 0.8%PRS 16.6%
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CSI 0.2rCSI 1.6%PRS 16.4%
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CSI 0.2rCSI 0.6%PRS 18.6%
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CSI 0.2rCSI 1.8%PRS 32.6%
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CSI 0.2rCSI 0.2%PRS 8.3%
-
CSI 0.2rCSI 0.4%PRS 22.5%
-
CSI 0.2rCSI 3.1%PRS 28.2%
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CSI 0.2rCSI 0.9%PRS 15.3%
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CSI 0.2rCSI 4.2%PRS 45.0%
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CSI 0.3rCSI 1.4%PRS 28.3%
-
CSI 0.3rCSI 0.7%PRS 18.9%
-
CSI 0.3rCSI 0.5%PRS 24.8%
-
CSI 0.3rCSI 0.3%PRS 14.0%
-
CSI 0.3rCSI 0.3%PRS 13.0%
-
CSI 0.3rCSI 0.5%PRS 14.7%
-
CSI 0.3rCSI 0.5%PRS 11.4%
-
CSI 0.3rCSI 3.4%PRS 57.6%
-
CSI 0.3rCSI 0.9%PRS 22.2%
-
CSI 0.3rCSI 0.6%PRS 15.1%
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CSI 0.3rCSI 3.6%PRS 22.0%
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CSI 0.4rCSI 9.1%PRS 53.2%
-
CSI 0.4rCSI 0.4%PRS 9.7%
-
CSI 0.4rCSI 0.3%PRS 15.4%
-
CSI 0.4rCSI 2.1%PRS 21.6%
-
CSI 0.4rCSI 0.9%PRS 23.4%
-
CSI 0.4rCSI 1.1%PRS 18.8%
-
CSI 0.4rCSI 0.4%PRS 12.1%
-
CSI 0.5rCSI 3.2%PRS 35.1%
-
CSI 0.5rCSI 0.7%PRS 13.3%
-
CSI 0.5rCSI 2.5%PRS 36.0%
-
CSI 0.5rCSI 0.6%PRS 11.2%
-
CSI 0.5rCSI 2.2%PRS 7.5%
-
CSI 0.5rCSI 1.8%PRS 23.7%
-
CSI 0.5rCSI 1.1%PRS 12.9%
-
CSI 0.5rCSI 2.2%PRS 27.4%
-
CSI 0.5rCSI 2.1%PRS 11.3%
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CSI 0.5rCSI 1.9%PRS 20.0%
-
CSI 0.5rCSI 3.4%PRS 9.0%
-
CSI 0.5rCSI 0.5%PRS 32.5%
-
CSI 0.6rCSI 2.3%PRS 11.9%
-
CSI 0.6rCSI 6.3%PRS 30.1%
-
CSI 0.6rCSI 0.4%PRS 10.3%
-
CSI 0.6rCSI 1.6%PRS 20.6%
-
CSI 0.6rCSI 0.9%PRS 12.0%
-
CSI 0.6rCSI 0.7%PRS 19.6%
-
CSI 0.6rCSI 2.3%PRS 11.8%
-
CSI 0.6rCSI 0.7%PRS 16.8%
-
CSI 0.6rCSI 1.3%PRS 18.4%
-
CSI 0.6rCSI 14.5%PRS 20.2%
-
CSI 0.6rCSI 1.3%PRS 17.5%
-
CSI 0.6rCSI 0.9%PRS 18.9%
-
CSI 0.6rCSI 0.5%PRS 11.9%
-
CSI 0.7rCSI 2.1%PRS 12.5%
-
CSI 0.7rCSI 4.1%PRS 32.6%
-
CSI 0.7rCSI 0.9%PRS 13.1%
-
CSI 0.7rCSI 1.0%PRS 10.5%
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CSI 0.7rCSI 3.0%PRS 4.3%
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CSI 0.7rCSI 7.9%PRS 43.2%
-
CSI 0.7rCSI 0.5%PRS 11.8%
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CSI 0.7rCSI 1.1%PRS 13.1%
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CSI 0.8rCSI 2.6%PRS 8.1%
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CSI 0.8rCSI 9.5%PRS 11.8%
-
CSI 0.8rCSI 2.7%PRS 8.2%
-
CSI 0.9rCSI 4.9%PRS 17.6%
-
CSI 0.9rCSI 1.4%PRS 9.8%
-
CSI 0.9rCSI 8.5%PRS 47.5%
-
CSI 0.9rCSI 2.4%PRS 9.9%
-
CSI 0.9rCSI 2.7%PRS 37.6%
-
CSI 0.9rCSI 2.1%PRS 15.9%
-
CSI 0.9rCSI 1.9%PRS 11.7%
-
CSI 0.9rCSI 2.3%PRS 17.2%
-
CSI 0.9rCSI 1.4%PRS 11.2%
-
CSI 0.9rCSI 0.6%PRS 15.6%
-
CSI 1.0rCSI 2.4%PRS 14.1%
-
CSI 1.0rCSI 3.1%PRS 16.7%
-
CSI 1.0rCSI 0.7%PRS 10.2%
-
CSI 1.0rCSI 11.0%PRS 20.7%
-
CSI 1.0rCSI 0.7%PRS 13.3%
-
CSI 1.0rCSI 1.6%PRS 14.3%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Comma-separated if multiple.
Comma-separated if multiple.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Disclaimer: This in-silico analysis is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
Genular Protein ID: 2755155281
Symbol: OLA1_HUMAN
Name: DNA damage-regulated overexpressed in cancer 45
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 20053727
Title: DOC45, a novel DNA damage-regulated nucleocytoplasmic ATPase that is overexpressed in multiple human malignancies.
PubMed ID: 20053727
PubMed ID: 11230166
Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.
PubMed ID: 11230166
DOI: 10.1101/gr.gr1547r
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 17430889
Title: Human OLA1 defines an ATPase subfamily in the Obg family of GTP-binding proteins.
PubMed ID: 17430889
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 396
- Mass: 44744
- Checksum: 4C7629BFC27CBEB2
- Sequence:
MPPKKGGDGI KPPPIIGRFG TSLKIGIVGL PNVGKSTFFN VLTNSQASAE NFPFCTIDPN ESRVPVPDER FDFLCQYHKP ASKIPAFLNV VDIAGLVKGA HNGQGLGNAF LSHISACDGI FHLTRAFEDD DITHVEGSVD PIRDIEIIHE ELQLKDEEMI GPIIDKLEKV AVRGGDKKLK PEYDIMCKVK SWVIDQKKPV RFYHDWNDKE IEVLNKHLFL TSKPMVYLVN LSEKDYIRKK NKWLIKIKEW VDKYDPGALV IPFSGALELK LQELSAEERQ KYLEANMTQS ALPKIIKAGF AALQLEYFFT AGPDEVRAWT IRKGTKAPQA AGKIHTDFEK GFIMAEVMKY EDFKEEGSEN AVKAAGKYRQ QGRNYIVEDG DIIFFKFNTP QQPKKK