Details for: UBIAD1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 1.35
Marker Score: 2,563 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.12
Marker Score: 17,555 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,740 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,965 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,399 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.98
Marker Score: 589 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,402 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.93
Marker Score: 480 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.92
Marker Score: 436 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,713 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,246 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.86
Marker Score: 4,922 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 308 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.85
Marker Score: 1,067 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.82
Marker Score: 1,668 - Cell Name: plasmablast (CL0000980)
Fold Change: 0.81
Marker Score: 1,075 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,262 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.75
Marker Score: 301 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.75
Marker Score: 216 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.74
Marker Score: 567 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.72
Marker Score: 374 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.69
Marker Score: 2,889 - Cell Name: brush cell (CL0002204)
Fold Change: 0.67
Marker Score: 611 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.67
Marker Score: 171 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.67
Marker Score: 318 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: 0.66
Marker Score: 2,573 - Cell Name: blood cell (CL0000081)
Fold Change: 0.61
Marker Score: 7,136 - Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
Fold Change: 0.59
Marker Score: 1,150 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.58
Marker Score: 395 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 0.58
Marker Score: 620 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 0.57
Marker Score: 2,397 - Cell Name: B-1 B cell (CL0000819)
Fold Change: 0.55
Marker Score: 960 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.54
Marker Score: 431 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.54
Marker Score: 775 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.54
Marker Score: 3,227 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.53
Marker Score: 234 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 0.52
Marker Score: 391 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 0.52
Marker Score: 27,527 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.52
Marker Score: 342 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.52
Marker Score: 1,179 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.51
Marker Score: 791 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.5
Marker Score: 490 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.5
Marker Score: 524 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.5
Marker Score: 202 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 0.49
Marker Score: 260 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.49
Marker Score: 512 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.49
Marker Score: 1,894 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.49
Marker Score: 130 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 0.49
Marker Score: 268 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 0.48
Marker Score: 2,077 - Cell Name: Unknown (CL0000548)
Fold Change: 0.47
Marker Score: 345 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.47
Marker Score: 508 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.47
Marker Score: 1,109 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.47
Marker Score: 332 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.47
Marker Score: 1,391 - Cell Name: mature B cell (CL0000785)
Fold Change: 0.47
Marker Score: 342 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.46
Marker Score: 145 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.46
Marker Score: 315 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.46
Marker Score: 1,763 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 0.46
Marker Score: 1,120 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.45
Marker Score: 99 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 0.45
Marker Score: 640 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.45
Marker Score: 145 - Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
Fold Change: 0.45
Marker Score: 801 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.44
Marker Score: 153 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.43
Marker Score: 398 - Cell Name: neural cell (CL0002319)
Fold Change: 0.43
Marker Score: 209 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.43
Marker Score: 181 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.43
Marker Score: 6,471 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 0.43
Marker Score: 449 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.43
Marker Score: 414 - Cell Name: class switched memory B cell (CL0000972)
Fold Change: 0.43
Marker Score: 403 - Cell Name: neuron (CL0000540)
Fold Change: 0.43
Marker Score: 1,741 - Cell Name: malignant cell (CL0001064)
Fold Change: 0.43
Marker Score: 5,733 - Cell Name: cardiac mesenchymal cell (CL0000569)
Fold Change: 0.43
Marker Score: 105 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.43
Marker Score: 429 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.43
Marker Score: 899 - Cell Name: osteoclast (CL0000092)
Fold Change: 0.43
Marker Score: 212 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.42
Marker Score: 3,648 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.42
Marker Score: 268 - Cell Name: stem cell (CL0000034)
Fold Change: 0.42
Marker Score: 1,008 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.42
Marker Score: 377 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.42
Marker Score: 418 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 0.42
Marker Score: 3,130 - Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
Fold Change: 0.42
Marker Score: 307 - Cell Name: bronchial epithelial cell (CL0002328)
Fold Change: 0.42
Marker Score: 111 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.42
Marker Score: 1,020 - Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
Fold Change: 0.42
Marker Score: 125 - Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
Fold Change: 0.42
Marker Score: 203 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 0.42
Marker Score: 452 - Cell Name: double negative T regulatory cell (CL0011024)
Fold Change: 0.41
Marker Score: 401 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.41
Marker Score: 15,296 - Cell Name: mononuclear phagocyte (CL0000113)
Fold Change: 0.41
Marker Score: 416 - Cell Name: mesenchymal lymphangioblast (CL0005021)
Fold Change: 0.41
Marker Score: 92 - Cell Name: large intestine goblet cell (CL1000320)
Fold Change: 0.41
Marker Score: 109 - Cell Name: memory B cell (CL0000787)
Fold Change: 0.41
Marker Score: 311 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: 0.41
Marker Score: 178 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.4
Marker Score: 128 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.4
Marker Score: 96 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.4
Marker Score: 2,563
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 769478474
Symbol: UBIA1_HUMAN
Name: UbiA prenyltransferase domain-containing protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11314041
Title: Isolation and characterization of the TERE1 gene, a gene down-regulated in transitional cell carcinoma of the bladder.
PubMed ID: 11314041
PubMed ID: 16303743
Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.
PubMed ID: 16303743
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12497587
Title: TERE1, a novel gene affecting growth regulation in prostate carcinoma.
PubMed ID: 12497587
DOI: 10.1002/pros.10174
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 20953171
Title: Identification of UBIAD1 as a novel human menaquinone-4 biosynthetic enzyme.
PubMed ID: 20953171
DOI: 10.1038/nature09464
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 23374346
Title: Ubiad1 is an antioxidant enzyme that regulates eNOS activity by CoQ10 synthesis.
PubMed ID: 23374346
PubMed ID: 17962451
Title: Mutations in the UBIAD1 gene on chromosome short arm 1, region 36, cause Schnyder crystalline corneal dystrophy.
PubMed ID: 17962451
DOI: 10.1167/iovs.07-0845
PubMed ID: 17668063
Title: Mutations in the UBIAD1 gene, encoding a potential prenyltransferase, are causal for Schnyder crystalline corneal dystrophy.
PubMed ID: 17668063
PubMed ID: 18176953
Title: Genetic analysis of 14 families with Schnyder crystalline corneal dystrophy reveals clues to UBIAD1 protein function.
PubMed ID: 18176953
DOI: 10.1002/ajmg.a.32201
PubMed ID: 19429578
Title: Surgical management and genetic analysis of a Chinese family with the S171P mutation in the UBIAD1 gene, the gene for Schnyder corneal dystrophy.
PubMed ID: 19429578
PubMed ID: 19649163
Title: A novel UBIAD1 mutation identified in a Chinese family with Schnyder crystalline corneal dystrophy.
PubMed ID: 19649163
PubMed ID: 20489584
Title: Newly reported p.Asp240Asn mutation in UBIAD1 suggests central discoid corneal dystrophy is a variant of Schnyder corneal dystrophy.
PubMed ID: 20489584
PubMed ID: 20505825
Title: UBIAD1 mutation alters a mitochondrial prenyltransferase to cause Schnyder corneal dystrophy.
PubMed ID: 20505825
PubMed ID: 23169578
Title: The UBIAD1 prenyltransferase links menaquione-4 synthesis to cholesterol metabolic enzymes.
PubMed ID: 23169578
DOI: 10.1002/humu.22230
Sequence Information:
- Length: 338
- Mass: 36831
- Checksum: 02808542DB9EA249
- Sequence:
MAASQVLGEK INILSGETVK AGDRDPLGND CPEQDRLPQR SWRQKCASYV LALRPWSFSA SLTPVALGSA LAYRSHGVLD PRLLVGCAVA VLAVHGAGNL VNTYYDFSKG IDHKKSDDRT LVDRILEPQD VVRFGVFLYT LGCVCAACLY YLSPLKLEHL ALIYFGGLSG SFLYTGGIGF KYVALGDLII LITFGPLAVM FAYAIQVGSL AIFPLVYAIP LALSTEAILH SNNTRDMESD REAGIVTLAI LIGPTFSYIL YNTLLFLPYL VFSILATHCT ISLALPLLTI PMAFSLERQF RSQAFNKLPQ RTAKLNLLLG LFYVFGIILA PAGSLPKI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.