Details for: PYCR2

Gene ID: 29920

Symbol: PYCR2

Ensembl ID: ENSG00000143811

Description: pyrroline-5-carboxylate reductase 2

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.56
    Marker Score: 6,135
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: 1.52
    Marker Score: 921
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 1.49
    Marker Score: 6,114
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 1.46
    Marker Score: 1,526
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 1.34
    Marker Score: 908
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 1.32
    Marker Score: 956
  • Cell Name: germ cell (CL0000586)
    Fold Change: 1.27
    Marker Score: 2,225
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 1.27
    Marker Score: 11,056
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.21
    Marker Score: 5,200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 1.19
    Marker Score: 1,232
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.18
    Marker Score: 836
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 1.13
    Marker Score: 364
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.07
    Marker Score: 1,571
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,678
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 0.99
    Marker Score: 47,903
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: 0.98
    Marker Score: 1,871
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 0.98
    Marker Score: 1,579
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,391
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: 0.98
    Marker Score: 286
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.97
    Marker Score: 288
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: 0.95
    Marker Score: 530
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2,389
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.92
    Marker Score: 476
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.92
    Marker Score: 433
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.9
    Marker Score: 2,687
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.88
    Marker Score: 5,024
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 0.87
    Marker Score: 252
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.87
    Marker Score: 8,830
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.87
    Marker Score: 920
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.87
    Marker Score: 1,813
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 0.86
    Marker Score: 2,123
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.86
    Marker Score: 5,226
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.86
    Marker Score: 2,096
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.85
    Marker Score: 306
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.85
    Marker Score: 851
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 0.84
    Marker Score: 710
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 0.82
    Marker Score: 20,949
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.81
    Marker Score: 1,369
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.79
    Marker Score: 27,459
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.79
    Marker Score: 316
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 0.78
    Marker Score: 7,733
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.78
    Marker Score: 356
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1,262
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.78
    Marker Score: 566
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 0.77
    Marker Score: 1,110
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 0.77
    Marker Score: 1,227
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 0.77
    Marker Score: 2,086
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 0.77
    Marker Score: 189
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 0.76
    Marker Score: 2,136
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 0.76
    Marker Score: 153
  • Cell Name: P/D1 enteroendocrine cell (CL0002268)
    Fold Change: 0.75
    Marker Score: 279
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 0.75
    Marker Score: 355
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.75
    Marker Score: 2,133
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.75
    Marker Score: 571
  • Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
    Fold Change: 0.74
    Marker Score: 2,158
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 0.74
    Marker Score: 2,031
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.73
    Marker Score: 402
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.72
    Marker Score: 372
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.72
    Marker Score: 792
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.72
    Marker Score: 8,054
  • Cell Name: mesenchymal lymphangioblast (CL0005021)
    Fold Change: 0.71
    Marker Score: 158
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.7
    Marker Score: 2,584
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 0.7
    Marker Score: 348
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 0.7
    Marker Score: 706
  • Cell Name: type G enteroendocrine cell (CL0000508)
    Fold Change: 0.69
    Marker Score: 237
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.68
    Marker Score: 457
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.68
    Marker Score: 175
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: 0.68
    Marker Score: 351
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.68
    Marker Score: 714
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: 0.68
    Marker Score: 390
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 0.67
    Marker Score: 3,521
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.67
    Marker Score: 160
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 0.67
    Marker Score: 1,336
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 0.67
    Marker Score: 4,359
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 0.67
    Marker Score: 456
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.67
    Marker Score: 2,795
  • Cell Name: plasma cell (CL0000786)
    Fold Change: 0.67
    Marker Score: 743
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.66
    Marker Score: 605
  • Cell Name: glandular cell of esophagus (CL0002657)
    Fold Change: 0.66
    Marker Score: 210
  • Cell Name: blood vessel smooth muscle cell (CL0019018)
    Fold Change: 0.66
    Marker Score: 174
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.66
    Marker Score: 437
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 0.66
    Marker Score: 1,203
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 0.66
    Marker Score: 872
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 0.65
    Marker Score: 666
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 0.65
    Marker Score: 681
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 0.64
    Marker Score: 2,746
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: 0.64
    Marker Score: 163
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: 0.64
    Marker Score: 230
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.64
    Marker Score: 260
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.64
    Marker Score: 169
  • Cell Name: enteroendocrine cell (CL0000164)
    Fold Change: 0.64
    Marker Score: 330
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 0.64
    Marker Score: 1,056
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: 0.64
    Marker Score: 220
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.64
    Marker Score: 568
  • Cell Name: Schwann cell precursor (CL0002375)
    Fold Change: 0.64
    Marker Score: 158
  • Cell Name: hematopoietic precursor cell (CL0008001)
    Fold Change: 0.63
    Marker Score: 222
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 0.63
    Marker Score: 315
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 0.63
    Marker Score: 497
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 0.63
    Marker Score: 166
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.63
    Marker Score: 145

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PYCR2 is a member of the pyrroline-5-carboxylate reductase family, which is involved in the biosynthesis of proline, a non-essential amino acid with diverse cellular functions. The gene is highly expressed in various cell types, including placental villous trophoblast, myeloid dendritic cells, pro-T cells, and hematopoietic stem cells. This widespread expression suggests a critical role in maintaining cellular homeostasis and immune function. **Pathways and Functions:** PYCR2 is involved in several key pathways, including: 1. **Cellular response to oxidative stress:** PYCR2 helps to mitigate oxidative damage by reducing pyrroline-5-carboxylate, a reactive intermediate in the proline biosynthetic pathway. 2. **Glutamate and glutamine metabolism:** PYCR2 is also implicated in the regulation of glutamate and glutamine metabolism, which are crucial for maintaining glutathione levels and redox homeostasis. 3. **Proline biosynthetic process:** As a key enzyme in the proline biosynthetic pathway, PYCR2 is essential for the production of proline, which is involved in collagen synthesis, cell signaling, and antioxidant defense. 4. **Mitochondrial matrix and mitochondrial function:** PYCR2 is localized to the mitochondrial matrix, where it plays a role in regulating mitochondrial function and biogenesis. **Clinical Significance:** The dysregulation of PYCR2 has been implicated in various diseases, including: 1. **Autoimmune disorders:** Alterations in PYCR2 expression have been linked to autoimmune diseases, such as rheumatoid arthritis and lupus, where proline biosynthesis is disrupted. 2. **Cancer:** PYCR2 has been shown to be overexpressed in various types of cancer, including breast, lung, and colon cancer, where proline biosynthesis is dysregulated. 3. **Neurological disorders:** PYCR2 has been implicated in neurological disorders, such as Alzheimer's disease and Parkinson's disease, where oxidative stress and mitochondrial dysfunction are prominent features. In conclusion, PYCR2 is a multifunctional gene that plays a critical role in maintaining cellular homeostasis, immune function, and metabolic regulation. Its dysregulation has been implicated in various diseases, highlighting the importance of PYCR2 in human health and disease. Further research is needed to fully elucidate the mechanisms by which PYCR2 regulates cellular processes and to explore its therapeutic potential in disease prevention and treatment.

Genular Protein ID: 3818514575

Symbol: P5CR2_HUMAN

Name: Pyrroline-5-carboxylate reductase 2

UniProtKB Accession Codes:

Q96C36 A8K798 Q7Z515 Q9Y5J4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 15 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EC 3 EMBL 6 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 6 Gene3D 2 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HAMAP 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PCDDB 1 PDB 2 PDBsum 1 PIRSF 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 Rhea 2 SABIO-RK 1 SAM 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TopDownProteomics 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 6894153

Title: Pyrroline-5-carboxylate reductase in human erythrocytes.

PubMed ID: 6894153

DOI: 10.1172/jci110115

PubMed ID: 2722838

Title: Purified human erythrocyte pyrroline-5-carboxylate reductase. Preferential oxidation of NADPH.

PubMed ID: 2722838

DOI: 10.1016/s0021-9258(18)60538-1

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23024808

Title: Functional specialization in proline biosynthesis of melanoma.

PubMed ID: 23024808

DOI: 10.1371/journal.pone.0045190

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24930674

Title: Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production.

PubMed ID: 24930674

DOI: 10.18632/oncotarget.1561

PubMed ID: 25865492

Title: Mutations in PYCR2, encoding pyrroline-5-carboxylate reductase 2, cause microcephaly and hypomyelination.

PubMed ID: 25865492

DOI: 10.1016/j.ajhg.2015.03.003

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

Sequence Information:

  • Length: 320
  • Mass: 33637
  • Checksum: 9348455A64CCE722
  • Sequence:
    • MSVGFIGAGQ LAYALARGFT AAGILSAHKI IASSPEMNLP TVSALRKMGV NLTRSNKETV 
KHSDVLFLAV KPHIIPFILD EIGADVQARH IVVSCAAGVT ISSVEKKLMA FQPAPKVIRC 
MTNTPVVVQE GATVYATGTH ALVEDGQLLE QLMSSVGFCT EVEEDLIDAV TGLSGSGPAY 
AFMALDALAD GGVKMGLPRR LAIQLGAQAL LGAAKMLLDS EQHPCQLKDN VCSPGGATIH 
ALHFLESGGF RSLLINAVEA SCIRTRELQS MADQEKISPA ALKKTLLDRV KLESPTVSTL 
TPSSPGKLLT RSLALGGKKD

Genular Protein ID: 2412144807

Symbol: A0A087WTV6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WTV6

Database IDs:

ARBA 13 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 10 ChiTaRS 1 DNASU 1 EC 2 EMBL 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 1 GeneTree 1 GenomeRNAi 1 HAMAP 1 HGNC 1 InterPro 5 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 4 Proteomes 2 RefSeq 1 Rhea 2 SMR 1 SUPFAM 2 UCSC 1 UniPathway 1 VEuPathDB 1

Citations:

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 246
  • Mass: 25868
  • Checksum: F7B8C99BC92FFA85
  • Sequence:
    • MSVGFIGAGQ LAYALARGFT AAGILSAHKI IASSPEMNLP TVSALRKMGV NLTRSNKETV 
KHSDVLFLAV KPHIIPFILD EIGADVQARH IVVSCAAGVT ISSVEKAFMA LDALADGGVK 
MGLPRRLAIQ LGAQALLGAA KMLLDSEQHP CQLKDNVCSP GGATIHALHF LESGGFRSLL 
INAVEASCIR TRELQSMADQ EKISPAALKK TLLDRVKLES PTVSTLTPSS PGKLLTRSLA 
LGGKKD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.