Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 413.1917
Cell Significance Index: -64.2700 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 265.6091
Cell Significance Index: -67.3700 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 146.2332
Cell Significance Index: -69.0400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 138.2130
Cell Significance Index: -56.1500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 58.9688
Cell Significance Index: -56.3000 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 54.5599
Cell Significance Index: -67.2700 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 24.4358
Cell Significance Index: -65.4600 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 19.1538
Cell Significance Index: -58.8300 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 17.3794
Cell Significance Index: -68.5800 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 16.3119
Cell Significance Index: -35.7000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 3.6075
Cell Significance Index: 92.7300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.5694
Cell Significance Index: 144.1800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.5147
Cell Significance Index: 499.0500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 2.4208
Cell Significance Index: 185.7700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.3049
Cell Significance Index: 462.3600 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 2.2728
Cell Significance Index: 55.4600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.9333
Cell Significance Index: 693.4300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.8139
Cell Significance Index: 1254.5700 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 1.7312
Cell Significance Index: 37.0100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.6514
Cell Significance Index: 1491.1000 - Cell Name: type II muscle cell (CL0002212)
Fold Change: 1.6411
Cell Significance Index: 26.4800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.6192
Cell Significance Index: 45.2500 - Cell Name: preadipocyte (CL0002334)
Fold Change: 1.2994
Cell Significance Index: 25.3600 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.2069
Cell Significance Index: 20.3300 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9045
Cell Significance Index: 147.1100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.8307
Cell Significance Index: 55.8600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.7868
Cell Significance Index: 85.5900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.6739
Cell Significance Index: 19.4200 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.6258
Cell Significance Index: 10.0400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.6143
Cell Significance Index: 32.0000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.6059
Cell Significance Index: 1140.7800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.5483
Cell Significance Index: 248.8400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.5441
Cell Significance Index: 24.6600 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.5340
Cell Significance Index: 7.6800 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.5017
Cell Significance Index: 10.8700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.5004
Cell Significance Index: 18.9500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.4709
Cell Significance Index: 20.8300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.4176
Cell Significance Index: 75.2800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.3981
Cell Significance Index: 252.8500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.3956
Cell Significance Index: 48.6500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.3495
Cell Significance Index: 48.0000 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.3331
Cell Significance Index: 20.0000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3221
Cell Significance Index: 175.9200 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.2810
Cell Significance Index: 432.6100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2686
Cell Significance Index: 118.7500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2519
Cell Significance Index: 47.9400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.2493
Cell Significance Index: 459.8500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.2488
Cell Significance Index: 24.6100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.1994
Cell Significance Index: 271.1400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.1958
Cell Significance Index: 3.3600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1796
Cell Significance Index: 6.3100 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.1034
Cell Significance Index: 2.9500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0253
Cell Significance Index: 1.1800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0041
Cell Significance Index: 0.1100 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.0264
Cell Significance Index: -0.3900 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0365
Cell Significance Index: -4.6800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0449
Cell Significance Index: -4.6700 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0523
Cell Significance Index: -38.3800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0742
Cell Significance Index: -55.0000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0778
Cell Significance Index: -58.8600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1120
Cell Significance Index: -63.1700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1220
Cell Significance Index: -76.2100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1364
Cell Significance Index: -6.4100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1478
Cell Significance Index: -7.6800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1677
Cell Significance Index: -21.6600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1923
Cell Significance Index: -32.8400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1968
Cell Significance Index: -28.6000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2071
Cell Significance Index: -59.5800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.2077
Cell Significance Index: -14.3700 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.2096
Cell Significance Index: -3.0100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.2290
Cell Significance Index: -14.4300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2716
Cell Significance Index: -20.2500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.3226
Cell Significance Index: -32.9500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.3356
Cell Significance Index: -39.5800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.3468
Cell Significance Index: -40.4200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.3470
Cell Significance Index: -73.1000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.3896
Cell Significance Index: -5.3200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.4107
Cell Significance Index: -11.0100 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.4186
Cell Significance Index: -11.4000 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.4316
Cell Significance Index: -6.3700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.4474
Cell Significance Index: -31.6500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.4606
Cell Significance Index: -29.7200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.4790
Cell Significance Index: -54.8800 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.5105
Cell Significance Index: -10.5900 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.5264
Cell Significance Index: -15.0900 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.6240
Cell Significance Index: -3.7700 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.6759
Cell Significance Index: -14.8000 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.6912
Cell Significance Index: -8.2400 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.7221
Cell Significance Index: -57.1900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.7282
Cell Significance Index: -38.2400 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.8084
Cell Significance Index: -10.0800 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.8870
Cell Significance Index: -6.0100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.9181
Cell Significance Index: -15.3700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.9433
Cell Significance Index: -57.9800 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -1.0722
Cell Significance Index: -37.2600 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -1.0818
Cell Significance Index: -15.4000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.0900
Cell Significance Index: -66.8300 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -1.1020
Cell Significance Index: -36.0800 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.1077
Cell Significance Index: -35.2800 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -1.1861
Cell Significance Index: -14.9700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2930612675
Symbol: STRN3_HUMAN
Name: Striatin-3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7864889
Title: A cell-cycle nuclear autoantigen containing WD-40 motifs expressed mainly in S and G2 phase cells.
PubMed ID: 7864889
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 12508121
Title: The DNA sequence and analysis of human chromosome 14.
PubMed ID: 12508121
DOI: 10.1038/nature01348
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10748158
Title: Zinedin, SG2NA, and striatin are calmodulin-binding, WD repeat proteins principally expressed in the brain.
PubMed ID: 10748158
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 18782753
Title: A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein.
PubMed ID: 18782753
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25743393
Title: CCM-3/STRIPAK promotes seamless tube extension through endocytic recycling.
PubMed ID: 25743393
DOI: 10.1038/ncomms7449
PubMed ID: 26876214
PubMed ID: 30622739
Title: Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling.
PubMed ID: 30622739
PubMed ID: 33633399
Title: Cryo-EM structure of the Hippo signaling integrator human STRIPAK.
PubMed ID: 33633399
Sequence Information:
- Length: 797
- Mass: 87209
- Checksum: 2179BD257186DFB0
- Sequence:
MDELAGGGGG GPGMAAPPRQ QQGPGGNLGL SPGGNGAAGG GGPPASEGAG PAAGPELSRP QQYTIPGILH YIQHEWARFE MERAHWEVER AELQARIAFL QGERKGQENL KKDLVRRIKM LEYALKQERA KYHKLKYGTE LNQGDLKMPT FESEETKDTE APTAPQNSQL TWKQGRQLLR QYLQEVGYTD TILDVRSQRV RSLLGLSNSE PNGSVETKNL EQILNGGESP KQKGQEIKRS SGDVLETFNF LENADDSDED EENDMIEGIP EGKDKHRMNK HKIGNEGLAA DLTDDPDTEE ALKEFDFLVT AEDGEGAGEA RSSGDGTEWD KDDLSPTAEV WDVDQGLISK LKEQYKKERK GKKGVKRANR TKLYDMIADL GDDELPHIPS GIINQSRSAS TRMTDHEGAR AEEAEPITFP SGGGKSFIMG SDDVLLSVLG LGDLADLTVT NDADYSYDLP ANKDAFRKTW NPKYTLRSHF DGVRALAFHP VEPVLVTASE DHTLKLWNLQ KTVPAKKSAS LDVEPIYTFR AHIGPVLSLA ISSNGEQCFS GGIDATIQWW NMPSPSVDPY DTYEPNVLAG TLVGHTDAVW GLAYSGIKNQ LLSCSADGTV RLWNPQEKLP CICTYNGDKK HGIPTSVDFI GCDPAHMVTS FNTGSAVIYD LETSQSLVIL SSQVDSGLQS NNHINRVVSH PTLPVTITAH EDRHIKFFDN KTGKMIHSMV AHLDAVTSLA VDPNGIYLMS GSHDCSIRLW NLDSKTCVQE ITAHRKKLDE SIYDVAFHSS KAYIASAGAD ALAKVFV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.