Details for: H2BC5

Gene ID: 3017

Symbol: H2BC5

Ensembl ID: ENSG00000158373

Description: H2B clustered histone 5

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: thymocyte (CL0000893)
    Fold Change: 4.57
    Marker Score: 4786
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 1.66
    Marker Score: 1132
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 1.57
    Marker Score: 913
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.47
    Marker Score: 169008
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.04
    Marker Score: 251757
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.03
    Marker Score: 947
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.01
    Marker Score: 324
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1
    Marker Score: 694
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71778
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48002
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 1
    Marker Score: 785
  • Cell Name: B-2 B cell (CL0000822)
    Fold Change: 1
    Marker Score: 1225
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30404
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.95
    Marker Score: 492
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2407
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.94
    Marker Score: 446
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.94
    Marker Score: 2304
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.92
    Marker Score: 9368
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2736
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.88
    Marker Score: 5006
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.88
    Marker Score: 1422
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.87
    Marker Score: 313
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5266
  • Cell Name: follicular B cell (CL0000843)
    Fold Change: 0.85
    Marker Score: 921
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.83
    Marker Score: 259
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.8
    Marker Score: 1878
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.78
    Marker Score: 1591
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 0.78
    Marker Score: 1919
  • Cell Name: epithelial cell of glomerular capsule (CL1000450)
    Fold Change: 0.78
    Marker Score: 199
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.77
    Marker Score: 6741
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.77
    Marker Score: 576
  • Cell Name: late pro-B cell (CL0002048)
    Fold Change: 0.77
    Marker Score: 905.5
  • Cell Name: small pre-B-II cell (CL0000954)
    Fold Change: 0.77
    Marker Score: 920
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.75
    Marker Score: 576
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 0.75
    Marker Score: 6517
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.75
    Marker Score: 664
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.74
    Marker Score: 298
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.74
    Marker Score: 382
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 0.73
    Marker Score: 295
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.73
    Marker Score: 2500
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.72
    Marker Score: 654
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 0.69
    Marker Score: 356
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.69
    Marker Score: 458
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.68
    Marker Score: 2868
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.67
    Marker Score: 172
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.67
    Marker Score: 305
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 0.66
    Marker Score: 3461
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 0.65
    Marker Score: 1159
  • Cell Name: IgA plasma cell (CL0000987)
    Fold Change: 0.62
    Marker Score: 527
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.62
    Marker Score: 743
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.61
    Marker Score: 593
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.61
    Marker Score: 902
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 0.6
    Marker Score: 723
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 0.6
    Marker Score: 562
  • Cell Name: type G enteroendocrine cell (CL0000508)
    Fold Change: 0.59
    Marker Score: 205
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 0.59
    Marker Score: 1070
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.58
    Marker Score: 579
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.58
    Marker Score: 371
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 0.58
    Marker Score: 1817
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 0.57
    Marker Score: 7629
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: 0.57
    Marker Score: 1077
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.56
    Marker Score: 1192
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 0.56
    Marker Score: 204
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.54
    Marker Score: 433
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 0.54
    Marker Score: 4226
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 0.53
    Marker Score: 2555
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 0.53
    Marker Score: 103
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.53
    Marker Score: 469
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.52
    Marker Score: 589
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.52
    Marker Score: 644.5
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 0.51
    Marker Score: 4409
  • Cell Name: blood vessel smooth muscle cell (CL0019018)
    Fold Change: 0.51
    Marker Score: 133
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.5
    Marker Score: 528.5
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 0.49
    Marker Score: 243
  • Cell Name: enteric neuron (CL0007011)
    Fold Change: 0.48
    Marker Score: 255
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.48
    Marker Score: 6344
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 0.47
    Marker Score: 316
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.47
    Marker Score: 16260.5
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.47
    Marker Score: 308
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 0.46
    Marker Score: 109
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.45
    Marker Score: 478
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 0.45
    Marker Score: 213
  • Cell Name: enteroendocrine cell (CL0000164)
    Fold Change: 0.45
    Marker Score: 232
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.45
    Marker Score: 118
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.44
    Marker Score: 747
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.44
    Marker Score: 925
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.44
    Marker Score: 114
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 0.44
    Marker Score: 312
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.43
    Marker Score: 258
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.43
    Marker Score: 443
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 0.43
    Marker Score: 566
  • Cell Name: epithelial cell of stratum germinativum of esophagus (CL1000447)
    Fold Change: 0.42
    Marker Score: 101
  • Cell Name: club cell (CL0000158)
    Fold Change: 0.4
    Marker Score: 472
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.4
    Marker Score: 116
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.4
    Marker Score: 435
  • Cell Name: peptic cell (CL0000155)
    Fold Change: 0.4
    Marker Score: 166
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 0.38
    Marker Score: 870
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.38
    Marker Score: 319
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.38
    Marker Score: 154
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 0.38
    Marker Score: 184

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Other Information

**Key characteristics**: - H2B5 is a member of the H2B family of histone proteins, which are responsible for packaging and organizing DNA within the nucleus. - It is a highly conserved protein, with similar sequences found in organisms from yeast to humans. - H2B5 is one of the most highly expressed histone proteins in the human genome. **Pathways and functions**: - H2B5 is involved in a variety of cellular processes, including differentiation, cell cycle regulation, stress responses, and chromatin remodeling. - It is essential for the proper development and function of the immune system. - It plays a role in the activation of hox genes during differentiation. - It is involved in the regulation of cell cycle progression and apoptosis. - H2B5 is also involved in stress responses, such as DNA repair and replication. **Clinical significance**: - Mutations in H2B5 have been linked to a number of human diseases, including cancer and developmental disorders. - In cancer, H2B5 mutations can lead to the activation of oncogenes and the development of tumors. - H2B5 inhibitors are being investigated as potential cancer therapies.

Genular Protein ID: 2335913751

Symbol: H2B1D_HUMAN

Name: Histone H2B type 1-D

UniProtKB Accession Codes:

P58876

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 2 ExpressionAtlas 1 GO 8 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRIDE 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 45 RefSeq 3 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniProtKB 8 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9710638

Title: Core histones and HIRIP3, a novel histone-binding protein, directly interact with WD repeat protein HIRA.

PubMed ID: 9710638

DOI: 10.1128/mcb.18.9.5546

PubMed ID: 1916825

Title: Isolation and characterization of two human H1 histone genes within clusters of core histone genes.

PubMed ID: 1916825

DOI: 10.1016/0888-7543(91)90183-f

PubMed ID: 12408966

Title: The human and mouse replication-dependent histone genes.

PubMed ID: 12408966

DOI: 10.1016/s0888-7543(02)96850-3

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16627869

Title: Quantitative proteomic analysis of post-translational modifications of human histones.

PubMed ID: 16627869

DOI: 10.1074/mcp.m600007-mcp200

PubMed ID: 12757711

Title: Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase.

PubMed ID: 12757711

DOI: 10.1016/s0092-8674(03)00355-6

PubMed ID: 16307923

Title: Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation.

PubMed ID: 16307923

DOI: 10.1016/j.molcel.2005.09.025

PubMed ID: 16283522

Title: Inhibition of core histones acetylation by carcinogenic nickel(II).

PubMed ID: 16283522

DOI: 10.1007/s11010-005-8285-1

PubMed ID: 16713563

Title: Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II.

PubMed ID: 16713563

DOI: 10.1016/j.cell.2006.04.029

PubMed ID: 16457587

Title: Gene-specific characterization of human histone H2B by electron capture dissociation.

PubMed ID: 16457587

DOI: 10.1021/pr050268v

PubMed ID: 16319397

Title: Characterization of histones H2A and H2B variants and their post-translational modifications by mass spectrometry.

PubMed ID: 16319397

DOI: 10.1074/mcp.m500288-mcp200

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21925322

Title: Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification.

PubMed ID: 21925322

DOI: 10.1016/j.cell.2011.08.008

PubMed ID: 21726816

Title: The RING finger protein MSL2 in the MOF complex is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation.

PubMed ID: 21726816

DOI: 10.1016/j.molcel.2011.05.015

PubMed ID: 22389435

Title: Lysine succinylation and lysine malonylation in histones.

PubMed ID: 22389435

DOI: 10.1074/mcp.m111.015875

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23824326

Title: USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing.

PubMed ID: 23824326

DOI: 10.1101/gad.211037.112

PubMed ID: 24681537

Title: Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark.

PubMed ID: 24681537

DOI: 10.1038/nchembio.1497

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 27105113

Title: Dynamic competing histone H4 K5K8 acetylation and butyrylation are hallmarks of highly active gene promoters.

PubMed ID: 27105113

DOI: 10.1016/j.molcel.2016.03.014

PubMed ID: 27105115

Title: Metabolic regulation of gene expression by histone lysine beta-hydroxybutyrylation.

PubMed ID: 27105115

DOI: 10.1016/j.molcel.2016.03.036

PubMed ID: 27723750

Title: Serine is a new target residue for endogenous ADP-ribosylation on histones.

PubMed ID: 27723750

DOI: 10.1038/nchembio.2180

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 27530147

Title: PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2).

PubMed ID: 27530147

DOI: 10.1038/ncomms12404

PubMed ID: 31542297

Title: Glutarylation of histone H4 lysine 91 regulates chromatin dynamics.

PubMed ID: 31542297

DOI: 10.1016/j.molcel.2019.08.018

PubMed ID: 31645732

Title: Metabolic regulation of gene expression by histone lactylation.

PubMed ID: 31645732

DOI: 10.1038/s41586-019-1678-1

PubMed ID: 34874266

Title: Serine ADP-ribosylation marks nucleosomes for ALC1-dependent chromatin remodeling.

PubMed ID: 34874266

DOI: 10.7554/elife.71502

Sequence Information:

  • Length: 126
  • Mass: 13936
  • Checksum: FAE8378A44BE7028
  • Sequence:
    • MPEPTKSAPA PKKGSKKAVT KAQKKDGKKR KRSRKESYSV YVYKVLKQVH PDTGISSKAM 
GIMNSFVNDI FERIAGEASR LAHYNKRSTI TSREIQTAVR LLLPGELAKH AVSEGTKAVT 
KYTSSK

Genular Protein ID: 3317911138

Symbol: H2B1C_HUMAN

Name: Histone H2B type 1-C/E/F/G/I

UniProtKB Accession Codes:

P62807 P02278 Q3B872 Q4VB69 Q93078 Q93080

Database IDs:

ABCD 1 AGR 6 AlphaFoldDB 1 Antibodypedia 5 Bgee 1 BioGRID 6 BioGRID-ORCS 6 BioMuta 1 CCDS 5 CTD 6 ChiTaRS 3 DIP 1 DMDM 1 DNASU 1 DisGeNET 6 DrugBank 1 EMBL 22 EMDB 42 EPD 1 Ensembl 8 ExpressionAtlas 1 GO 15 Gene3D 1 GeneCards 5 GeneTree 1 GeneWiki 5 Genevisible 1 GlyCosmos 1 GlyGen 1 HGNC 10 HOGENOM 1 HPA 5 InParanoid 1 IntAct 1 InterPro 3 KEGG 6 MANE-Select 5 MIM 5 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 5 OrthoDB 1 PANTHER 2 PDB 52 PDBsum 44 PIR 2 PRIDE 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 Pumba 1 RNAct 1 Reactome 45 RefSeq 6 SAM 1 SASBDB 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniProtKB 8 VEuPathDB 5 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1916825

Title: Isolation and characterization of two human H1 histone genes within clusters of core histone genes.

PubMed ID: 1916825

DOI: 10.1016/0888-7543(91)90183-f

PubMed ID: 9119399

Title: Human histone gene organization: nonregular arrangement within a large cluster.

PubMed ID: 9119399

DOI: 10.1006/geno.1996.4592

PubMed ID: 12408966

Title: The human and mouse replication-dependent histone genes.

PubMed ID: 12408966

DOI: 10.1016/s0888-7543(02)96850-3

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 422550

Title: Human spleen histone H2B. Isolation and amino acid sequence.

PubMed ID: 422550

DOI: 10.1093/oxfordjournals.jbchem.a132371

PubMed ID: 11859126

Title: Endotoxin-neutralizing antimicrobial proteins of the human placenta.

PubMed ID: 11859126

DOI: 10.4049/jimmunol.168.5.2356

PubMed ID: 8620898

Title: Biochemical and antibacterial analysis of human wound and blister fluid.

PubMed ID: 8620898

DOI: 10.1111/j.1432-1033.1996.0086n.x

PubMed ID: 12860195

Title: Antimicrobial peptides in the first line defence of human colon mucosa.

PubMed ID: 12860195

DOI: 10.1016/s0196-9781(03)00114-1

PubMed ID: 15019208

Title: Antimicrobial polypeptides of the human colonic epithelium.

PubMed ID: 15019208

DOI: 10.1016/j.peptides.2003.07.028

PubMed ID: 16627869

Title: Quantitative proteomic analysis of post-translational modifications of human histones.

PubMed ID: 16627869

DOI: 10.1074/mcp.m600007-mcp200

PubMed ID: 12757711

Title: Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase.

PubMed ID: 12757711

DOI: 10.1016/s0092-8674(03)00355-6

PubMed ID: 16307923

Title: Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation.

PubMed ID: 16307923

DOI: 10.1016/j.molcel.2005.09.025

PubMed ID: 16283522

Title: Inhibition of core histones acetylation by carcinogenic nickel(II).

PubMed ID: 16283522

DOI: 10.1007/s11010-005-8285-1

PubMed ID: 16713563

Title: Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II.

PubMed ID: 16713563

DOI: 10.1016/j.cell.2006.04.029

PubMed ID: 16457587

Title: Gene-specific characterization of human histone H2B by electron capture dissociation.

PubMed ID: 16457587

DOI: 10.1021/pr050268v

PubMed ID: 21726816

Title: The RING finger protein MSL2 in the MOF complex is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation.

PubMed ID: 21726816

DOI: 10.1016/j.molcel.2011.05.015

PubMed ID: 22121020

Title: GlcNAcylation of histone H2B facilitates its monoubiquitination.

PubMed ID: 22121020

DOI: 10.1038/nature10656

PubMed ID: 21925322

Title: Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification.

PubMed ID: 21925322

DOI: 10.1016/j.cell.2011.08.008

PubMed ID: 22389435

Title: Lysine succinylation and lysine malonylation in histones.

PubMed ID: 22389435

DOI: 10.1074/mcp.m111.015875

PubMed ID: 23824326

Title: USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing.

PubMed ID: 23824326

DOI: 10.1101/gad.211037.112

PubMed ID: 24681537

Title: Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark.

PubMed ID: 24681537

DOI: 10.1038/nchembio.1497

PubMed ID: 27105113

Title: Dynamic competing histone H4 K5K8 acetylation and butyrylation are hallmarks of highly active gene promoters.

PubMed ID: 27105113

DOI: 10.1016/j.molcel.2016.03.014

PubMed ID: 27105115

Title: Metabolic regulation of gene expression by histone lysine beta-hydroxybutyrylation.

PubMed ID: 27105115

DOI: 10.1016/j.molcel.2016.03.036

PubMed ID: 27530147

Title: PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2).

PubMed ID: 27530147

DOI: 10.1038/ncomms12404

PubMed ID: 31542297

Title: Glutarylation of histone H4 lysine 91 regulates chromatin dynamics.

PubMed ID: 31542297

DOI: 10.1016/j.molcel.2019.08.018

PubMed ID: 31645732

Title: Metabolic regulation of gene expression by histone lactylation.

PubMed ID: 31645732

DOI: 10.1038/s41586-019-1678-1

PubMed ID: 34874266

Title: Serine ADP-ribosylation marks nucleosomes for ALC1-dependent chromatin remodeling.

PubMed ID: 34874266

DOI: 10.7554/elife.71502

PubMed ID: 32911481

Title: The molecular basis of tight nuclear tethering and inactivation of cGAS.

PubMed ID: 32911481

DOI: 10.1038/s41586-020-2749-z

PubMed ID: 32911480

Title: Structural basis for sequestration and autoinhibition of cGAS by chromatin.

PubMed ID: 32911480

DOI: 10.1038/s41586-020-2748-0

PubMed ID: 32913000

Title: Structural basis of nucleosome-dependent cGAS inhibition.

PubMed ID: 32913000

DOI: 10.1126/science.abd0609

Sequence Information:

  • Length: 126
  • Mass: 13906
  • Checksum: FAE1479F44BE703D
  • Sequence:
    • MPEPAKSAPA PKKGSKKAVT KAQKKDGKKR KRSRKESYSV YVYKVLKQVH PDTGISSKAM 
GIMNSFVNDI FERIAGEASR LAHYNKRSTI TSREIQTAVR LLLPGELAKH AVSEGTKAVT 
KYTSSK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.