Details for: HNRNPF

Gene ID: 3185

Symbol: HNRNPF

Ensembl ID: ENSG00000169813

Description: heterogeneous nuclear ribonucleoprotein F

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 427.6570
    Cell Significance Index: -66.5200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 269.4728
    Cell Significance Index: -68.3500
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 231.0731
    Cell Significance Index: -95.1900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 199.7996
    Cell Significance Index: -81.1700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 195.2776
    Cell Significance Index: -92.2000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 177.0657
    Cell Significance Index: -91.0800
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 137.6557
    Cell Significance Index: -92.3700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 86.3898
    Cell Significance Index: -82.4800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 69.0130
    Cell Significance Index: -85.0900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 22.7417
    Cell Significance Index: -89.7400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 19.0641
    Cell Significance Index: -51.0700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 18.2129
    Cell Significance Index: -55.9400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 12.3870
    Cell Significance Index: -27.1100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 3.2378
    Cell Significance Index: 88.1300
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 3.2343
    Cell Significance Index: 57.1600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.9187
    Cell Significance Index: 85.7200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 2.8098
    Cell Significance Index: 345.5000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.7221
    Cell Significance Index: 78.0300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 2.6809
    Cell Significance Index: 126.0000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.5525
    Cell Significance Index: 350.5300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 2.4809
    Cell Significance Index: 292.5700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 2.4593
    Cell Significance Index: 85.4600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 2.4437
    Cell Significance Index: 182.1300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.3354
    Cell Significance Index: 1275.4000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 2.1937
    Cell Significance Index: 395.4600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.9993
    Cell Significance Index: 104.1400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.7997
    Cell Significance Index: 795.7000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.7973
    Cell Significance Index: 127.1100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.5893
    Cell Significance Index: 14.6400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.5584
    Cell Significance Index: 201.3300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.4980
    Cell Significance Index: 40.0000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.4130
    Cell Significance Index: 229.8100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.3721
    Cell Significance Index: 36.0800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.2280
    Cell Significance Index: 79.2300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.2142
    Cell Significance Index: 240.9600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.2085
    Cell Significance Index: 76.1700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.1827
    Cell Significance Index: 61.4400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 1.0067
    Cell Significance Index: 12.0000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.9799
    Cell Significance Index: 20.5100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.9243
    Cell Significance Index: 43.1000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.8589
    Cell Significance Index: 110.1000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.8433
    Cell Significance Index: 18.2700
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.7948
    Cell Significance Index: 8.6400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.6954
    Cell Significance Index: 7.9000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3693
    Cell Significance Index: 74.0900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2485
    Cell Significance Index: 42.4400
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.2413
    Cell Significance Index: 4.4600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2205
    Cell Significance Index: 21.8100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1919
    Cell Significance Index: 13.2700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1876
    Cell Significance Index: 35.7000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1411
    Cell Significance Index: 50.6000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0849
    Cell Significance Index: 2.4400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0817
    Cell Significance Index: 56.5000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0478
    Cell Significance Index: 36.2000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0255
    Cell Significance Index: 48.0200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0240
    Cell Significance Index: 0.6700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0227
    Cell Significance Index: 0.3800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0119
    Cell Significance Index: -21.9000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0150
    Cell Significance Index: -11.0800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0238
    Cell Significance Index: -36.6500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0245
    Cell Significance Index: -15.3100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0408
    Cell Significance Index: -29.9100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0466
    Cell Significance Index: -4.7600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0579
    Cell Significance Index: -78.6700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0608
    Cell Significance Index: -38.6100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1091
    Cell Significance Index: -61.5000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1128
    Cell Significance Index: -51.2100
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.1837
    Cell Significance Index: -1.1100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2186
    Cell Significance Index: -25.4800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2235
    Cell Significance Index: -47.0800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2389
    Cell Significance Index: -27.3700
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: -0.2413
    Cell Significance Index: -1.4900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2502
    Cell Significance Index: -72.0000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2655
    Cell Significance Index: -14.9000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3499
    Cell Significance Index: -8.9400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.3630
    Cell Significance Index: -52.7600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.3811
    Cell Significance Index: -22.8800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4396
    Cell Significance Index: -11.7600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.5019
    Cell Significance Index: -38.5200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.5182
    Cell Significance Index: -27.2100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.5318
    Cell Significance Index: -18.6900
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.6120
    Cell Significance Index: -14.1400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.6355
    Cell Significance Index: -8.6700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.7262
    Cell Significance Index: -44.6400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.7268
    Cell Significance Index: -82.9600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.8151
    Cell Significance Index: -84.8700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.8864
    Cell Significance Index: -70.2000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.8884
    Cell Significance Index: -44.9000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.9532
    Cell Significance Index: -30.5300
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.9920
    Cell Significance Index: -7.9200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -1.0004
    Cell Significance Index: -14.9900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.1027
    Cell Significance Index: -32.4800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -1.1759
    Cell Significance Index: -79.0700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -1.2920
    Cell Significance Index: -13.3800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.3476
    Cell Significance Index: -82.6200
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -1.4188
    Cell Significance Index: -18.1700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.4643
    Cell Significance Index: -39.2400
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -1.5158
    Cell Significance Index: -26.1300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -1.5392
    Cell Significance Index: -32.7800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.5548
    Cell Significance Index: -38.8700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** HNRNPF is a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family, which comprises a group of proteins that regulate RNA metabolism, including splicing, transport, and storage. HNRNPF is specifically characterized by its ability to bind to single-stranded RNA (ssRNA) and its involvement in various signaling pathways, including those mediated by cytokines, growth factors, and receptor tyrosine kinases. Its expression is widespread, with significant presence in immune cells, such as myeloid leukocytes, mature T cells, and type I NK T cells, as well as in non-immune cells, including fibroblasts, skeletal muscle satellite stem cells, and epithelial cells. **Pathways and Functions:** HNRNPF is involved in several key pathways, including: 1. **Cytokine Signaling in Immune System:** HNRNPF interacts with cytokines, such as interleukin-12 (IL-12), to regulate immune responses. This interaction is critical for the activation of immune cells, including T cells and natural killer (NK) cells. 2. **RNA Splicing:** HNRNPF plays a crucial role in the regulation of RNA splicing, a process that involves the removal of introns and the joining of exons to form a mature mRNA molecule. This process is essential for the production of functional proteins. 3. **Signaling by Receptor Tyrosine Kinases:** HNRNPF interacts with receptor tyrosine kinases, such as fibroblast growth factor receptor 2 (FGFR2), to regulate signaling pathways involved in cell proliferation, differentiation, and survival. 4. **Metabolism of RNA:** HNRNPF is involved in the regulation of RNA metabolism, including the processing of capped intron-containing pre-mRNA and the regulation of mRNA splicing via the spliceosome. **Clinical Significance:** HNRNPF's involvement in immune regulation and cellular processes has significant implications for our understanding of various disease states, including: 1. **Autoimmune Disorders:** Alterations in HNRNPF expression and function have been implicated in autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis. 2. **Cancer:** HNRNPF's role in RNA splicing and signaling pathways makes it a potential target for cancer therapy. 3. **Neurological Disorders:** HNRNPF's involvement in synaptic function and RNA metabolism suggests its potential role in neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, HNRNPF is a multifaceted gene that plays a critical role in various cellular processes, including RNA splicing, signaling pathways, and immune regulation. Its significance in both normal physiological processes and disease states highlights the importance of further research into the functions and clinical implications of HNRNPF.

Genular Protein ID: 636808024

Symbol: HNRPF_HUMAN

Name: Heterogeneous nuclear ribonucleoprotein F

UniProtKB Accession Codes:

P52597 B3KM84 Q5T0N2 Q96AU2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 1 EMBL 9 Ensembl 6 EvolutionaryTrace 1 ExpressionAtlas 1 GO 13 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OGP 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PIR 1 PRIDE 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 4 RefSeq 6 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7512260

Title: The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localization.

PubMed ID: 7512260

DOI: 10.1093/nar/22.6.1059

PubMed ID: 7499401

Title: Heterogeneous nuclear ribonucleoproteins H, H', and F are members of a ubiquitously expressed subfamily of related but distinct proteins encoded by genes mapping to different chromosomes.

PubMed ID: 7499401

DOI: 10.1074/jbc.270.48.28780

PubMed ID: 1351868

Title: Identification and characterization of a gene at D10S94 in the MEN2A region.

PubMed ID: 1351868

DOI: 10.1016/0888-7543(92)90251-m

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11054566

Title: Evidence that Dim1 associates with proteins involved in pre-mRNA splicing, and delineation of residues essential for Dim1 interactions with hnRNP F and Npw38/PQBP-1.

PubMed ID: 11054566

DOI: 10.1016/s0378-1119(00)00372-3

PubMed ID: 11991638

Title: Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

PubMed ID: 11991638

DOI: 10.1017/s1355838202021088

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 15161980

Title: Sumoylation of heterogeneous nuclear ribonucleoproteins, zinc finger proteins, and nuclear pore complex proteins: a proteomic analysis.

PubMed ID: 15161980

DOI: 10.1073/pnas.0402889101

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 17932509

Title: Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells.

PubMed ID: 17932509

DOI: 10.1038/sj.embor.7401088

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 16885237

Title: NMR structure of the three quasi RNA recognition motifs (qRRMs) of human hnRNP F and interaction studies with Bcl-x G-tract RNA: a novel mode of RNA recognition.

PubMed ID: 16885237

DOI: 10.1093/nar/gkl488

PubMed ID: 20526337

Title: Structural basis of G-tract recognition and encaging by hnRNP F quasi-RRMs.

PubMed ID: 20526337

DOI: 10.1038/nsmb.1814

Sequence Information:

  • Length: 415
  • Mass: 45672
  • Checksum: D14E170631FB1F31
  • Sequence:
    • MMLGPEGGEG FVVKLRGLPW SCSVEDVQNF LSDCTIHDGA AGVHFIYTRE GRQSGEAFVE 
LGSEDDVKMA LKKDRESMGH RYIEVFKSHR TEMDWVLKHS GPNSADSAND GFVRLRGLPF 
GCTKEEIVQF FSGLEIVPNG ITLPVDPEGK ITGEAFVQFA SQELAEKALG KHKERIGHRY 
IEVFKSSQEE VRSYSDPPLK FMSVQRPGPY DRPGTARRYI GIVKQAGLER MRPGAYSTGY 
GGYEEYSGLS DGYGFTTDLF GRDLSYCLSG MYDHRYGDSE FTVQSTTGHC VHMRGLPYKA 
TENDIYNFFS PLNPVRVHIE IGPDGRVTGE ADVEFATHEE AVAAMSKDRA NMQHRYIELF 
LNSTTGASNG AYSSQVMQGM GVSAAQATYS GLESQSVSGC YGAGYSGQNS MGGYD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.