Details for: HNRNPH1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 618.9840
Cell Significance Index: -96.2800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 409.4331
Cell Significance Index: -103.8500 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 292.0032
Cell Significance Index: -120.2900 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 252.3771
Cell Significance Index: -102.5300 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 252.3073
Cell Significance Index: -119.1200 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 225.8230
Cell Significance Index: -116.1600 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 177.8630
Cell Significance Index: -119.3500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 108.2386
Cell Significance Index: -103.3400 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 91.9579
Cell Significance Index: -113.3800 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 41.5289
Cell Significance Index: -111.2500 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 30.2290
Cell Significance Index: -119.2900 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 27.0523
Cell Significance Index: -83.0900 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 24.0932
Cell Significance Index: -52.7300 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 6.9215
Cell Significance Index: 102.1600 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 4.4290
Cell Significance Index: 126.9600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 3.7567
Cell Significance Index: 242.3600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 3.6938
Cell Significance Index: 103.2300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 3.1235
Cell Significance Index: 146.8000 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 2.8211
Cell Significance Index: 306.8500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.8100
Cell Significance Index: 385.8900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 2.7743
Cell Significance Index: 1226.5800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 2.7646
Cell Significance Index: 75.2500 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 2.6896
Cell Significance Index: 161.4700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.4357
Cell Significance Index: 136.6800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.3928
Cell Significance Index: 474.8700 - Cell Name: odontoblast (CL0000060)
Fold Change: 2.3427
Cell Significance Index: 300.3200 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 2.0611
Cell Significance Index: 107.3600 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.9706
Cell Significance Index: 89.3200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.7777
Cell Significance Index: 51.2200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.7739
Cell Significance Index: 355.8500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 1.6864
Cell Significance Index: 119.2700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.6381
Cell Significance Index: 295.3000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.5932
Cell Significance Index: 195.9000 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 1.5912
Cell Significance Index: 9.7900 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 1.4863
Cell Significance Index: 31.1100 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 1.4389
Cell Significance Index: 50.0000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.3047
Cell Significance Index: 712.5500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.1362
Cell Significance Index: 407.5400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.0783
Cell Significance Index: 127.1700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.9885
Cell Significance Index: 46.0900 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.9443
Cell Significance Index: 24.8300 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.7945
Cell Significance Index: 102.6400 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.6753
Cell Significance Index: 50.3300 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.6453
Cell Significance Index: 10.8700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.4621
Cell Significance Index: 12.3400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.4381
Cell Significance Index: 33.6200 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.4355
Cell Significance Index: 393.2500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4206
Cell Significance Index: 41.6100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.3866
Cell Significance Index: 66.0100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.3850
Cell Significance Index: 724.9900 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.3459
Cell Significance Index: 3.9300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.3344
Cell Significance Index: 11.7500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.3077
Cell Significance Index: 473.7500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.2906
Cell Significance Index: 184.5800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.2750
Cell Significance Index: 17.3400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.2311
Cell Significance Index: 426.1500 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.1681
Cell Significance Index: 2.8800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1656
Cell Significance Index: 31.5200 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.1566
Cell Significance Index: 7.9200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.1366
Cell Significance Index: 185.7800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.1017
Cell Significance Index: 46.1800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.0703
Cell Significance Index: 3.6500 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0645
Cell Significance Index: 1.0800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0072
Cell Significance Index: -0.3800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0221
Cell Significance Index: -16.7400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0412
Cell Significance Index: -30.2300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0614
Cell Significance Index: -45.5100 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0736
Cell Significance Index: -45.9500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.1528
Cell Significance Index: -24.8500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1580
Cell Significance Index: -89.0800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1582
Cell Significance Index: -16.1600 - Cell Name: peg cell (CL4033014)
Fold Change: -0.1766
Cell Significance Index: -4.0800 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.2054
Cell Significance Index: -23.4500 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2244
Cell Significance Index: -4.3800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2517
Cell Significance Index: -53.0100 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: -0.3211
Cell Significance Index: -2.4700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.3318
Cell Significance Index: -48.2300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.3577
Cell Significance Index: -102.9100 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.5344
Cell Significance Index: -5.8100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.6209
Cell Significance Index: -71.1400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.6594
Cell Significance Index: -21.1200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.6765
Cell Significance Index: -9.2300 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.7174
Cell Significance Index: -83.6000 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.8027
Cell Significance Index: -11.8500 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.8175
Cell Significance Index: -12.2500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.8837
Cell Significance Index: -92.0100 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -1.0777
Cell Significance Index: -26.9400 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -1.1330
Cell Significance Index: -24.1300 - Cell Name: pro-T cell (CL0000827)
Fold Change: -1.2264
Cell Significance Index: -31.3300 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -1.2277
Cell Significance Index: -21.7000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -1.2358
Cell Significance Index: -85.4600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -1.2739
Cell Significance Index: -32.7500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -1.3260
Cell Significance Index: -105.0200 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -1.3710
Cell Significance Index: -25.3400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -1.4944
Cell Significance Index: -32.3800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -1.5911
Cell Significance Index: -70.3800 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -1.6044
Cell Significance Index: -34.3000 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -1.7590
Cell Significance Index: -25.2600 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -1.8451
Cell Significance Index: -22.0000 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -1.8911
Cell Significance Index: -55.7000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3549899953
Symbol: HNRH1_HUMAN
Name: Heterogeneous nuclear ribonucleoprotein H
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7499401
Title: Heterogeneous nuclear ribonucleoproteins H, H', and F are members of a ubiquitously expressed subfamily of related but distinct proteins encoded by genes mapping to different chromosomes.
PubMed ID: 7499401
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7512260
Title: The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localization.
PubMed ID: 7512260
PubMed ID: 1286667
Title: Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes.
PubMed ID: 1286667
PubMed ID: 11003644
Title: Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein.
PubMed ID: 11003644
PubMed ID: 11991638
Title: Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.
PubMed ID: 11991638
PubMed ID: 15592455
Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.
PubMed ID: 15592455
DOI: 10.1038/nbt1046
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16946708
Title: Interaction of muscleblind, CUG-BP1 and hnRNP H proteins in DM1-associated aberrant IR splicing.
PubMed ID: 16946708
PubMed ID: 17289661
Title: Molecular composition of IMP1 ribonucleoprotein granules.
PubMed ID: 17289661
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 29938792
Title: Evidence for HNRNPH1 being another gene for Bain type syndromic mental retardation.
PubMed ID: 29938792
DOI: 10.1111/cge.13410
PubMed ID: 32335897
Title: HNRNPH1-related syndromic intellectual disability: Seven additional cases suggestive of a distinct syndromic neurodevelopmental syndrome.
PubMed ID: 32335897
DOI: 10.1111/cge.13765
Sequence Information:
- Length: 449
- Mass: 49229
- Checksum: 4ECF7A075C2526FF
- Sequence:
MMLGTEGGEG FVVKVRGLPW SCSADEVQRF FSDCKIQNGA QGIRFIYTRE GRPSGEAFVE LESEDEVKLA LKKDRETMGH RYVEVFKSNN VEMDWVLKHT GPNSPDTAND GFVRLRGLPF GCSKEEIVQF FSGLEIVPNG ITLPVDFQGR STGEAFVQFA SQEIAEKALK KHKERIGHRY IEIFKSSRAE VRTHYDPPRK LMAMQRPGPY DRPGAGRGYN SIGRGAGFER MRRGAYGGGY GGYDDYNGYN DGYGFGSDRF GRDLNYCFSG MSDHRYGDGG STFQSTTGHC VHMRGLPYRA TENDIYNFFS PLNPVRVHIE IGPDGRVTGE ADVEFATHED AVAAMSKDKA NMQHRYVELF LNSTAGASGG AYEHRYVELF LNSTAGASGG AYGSQMMGGM GLSNQSSYGG PASQQLSGGY GGGYGGQSSM SGYDQVLQEN SSDFQSNIA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.