Details for: HNRNPL
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 3.83
Marker Score: 3066 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 2.79
Marker Score: 155836 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 2.07
Marker Score: 109268 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 2.04
Marker Score: 2316 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 2.02
Marker Score: 13156 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 1.99
Marker Score: 5575 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 1.97
Marker Score: 6212 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 1.95
Marker Score: 5320 - Cell Name: Unknown (CL0002371)
Fold Change: 1.91
Marker Score: 2027 - Cell Name: Leydig cell (CL0000178)
Fold Change: 1.74
Marker Score: 1875 - Cell Name: granulosa cell (CL0000501)
Fold Change: 1.71
Marker Score: 17214 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.67
Marker Score: 56813 - Cell Name: naive regulatory T cell (CL0002677)
Fold Change: 1.63
Marker Score: 496 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 1.62
Marker Score: 9625 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 1.62
Marker Score: 21397 - Cell Name: CD38-negative naive B cell (CL0002102)
Fold Change: 1.57
Marker Score: 3294 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.56
Marker Score: 15835 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 1.53
Marker Score: 11411.5 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 1.49
Marker Score: 1863 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 1.48
Marker Score: 983.5 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 1.48
Marker Score: 1160 - Cell Name: Unknown (CL0000548)
Fold Change: 1.46
Marker Score: 1064 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 1.46
Marker Score: 1437 - Cell Name: ependymal cell (CL0000065)
Fold Change: 1.44
Marker Score: 503 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.44
Marker Score: 21537 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 1.44
Marker Score: 620 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 1.42
Marker Score: 340 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 1.42
Marker Score: 2994 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 1.41
Marker Score: 1190 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 1.4
Marker Score: 773 - Cell Name: stromal cell (CL0000499)
Fold Change: 1.39
Marker Score: 1634 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 1.39
Marker Score: 2279 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: 1.38
Marker Score: 833.5 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.36
Marker Score: 5052.5 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 1.36
Marker Score: 1457 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.36
Marker Score: 659 - Cell Name: plasmablast (CL0000980)
Fold Change: 1.34
Marker Score: 1785 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.34
Marker Score: 562 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 1.34
Marker Score: 1455 - Cell Name: common lymphoid progenitor (CL0000051)
Fold Change: 1.33
Marker Score: 903 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 1.32
Marker Score: 651 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 1.31
Marker Score: 1860 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.31
Marker Score: 5055.5 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 1.31
Marker Score: 527 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 1.3
Marker Score: 531 - Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 1.3
Marker Score: 475 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.3
Marker Score: 79814 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.3
Marker Score: 9943 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.29
Marker Score: 3841 - Cell Name: transitional stage B cell (CL0000818)
Fold Change: 1.28
Marker Score: 454 - Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 1.28
Marker Score: 2498 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 1.28
Marker Score: 397 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 1.28
Marker Score: 280 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.28
Marker Score: 47151 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.28
Marker Score: 400 - Cell Name: erythroid progenitor cell, mammalian (CL0001066)
Fold Change: 1.28
Marker Score: 409 - Cell Name: group 3 innate lymphoid cell (CL0001071)
Fold Change: 1.27
Marker Score: 535 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.27
Marker Score: 410 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.27
Marker Score: 403 - Cell Name: blood vessel smooth muscle cell (CL0019018)
Fold Change: 1.27
Marker Score: 334 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.27
Marker Score: 1165 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.27
Marker Score: 1099 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.27
Marker Score: 4887 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.27
Marker Score: 1866 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.26
Marker Score: 25145 - Cell Name: thymocyte (CL0000893)
Fold Change: 1.26
Marker Score: 1320 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 1.26
Marker Score: 789 - Cell Name: male germ cell (CL0000015)
Fold Change: 1.26
Marker Score: 362 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 1.25
Marker Score: 852 - Cell Name: oogonial cell (CL0000024)
Fold Change: 1.25
Marker Score: 1792.5 - Cell Name: common dendritic progenitor (CL0001029)
Fold Change: 1.24
Marker Score: 430 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 1.24
Marker Score: 312 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 1.24
Marker Score: 930 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 1.24
Marker Score: 3371 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.24
Marker Score: 47032 - Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
Fold Change: 1.24
Marker Score: 1157 - Cell Name: megakaryocyte (CL0000556)
Fold Change: 1.23
Marker Score: 700 - Cell Name: dendritic cell, human (CL0001056)
Fold Change: 1.23
Marker Score: 1251 - Cell Name: erythroblast (CL0000765)
Fold Change: 1.23
Marker Score: 765 - Cell Name: hepatocyte (CL0000182)
Fold Change: 1.22
Marker Score: 835 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 1.22
Marker Score: 1229 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 1.22
Marker Score: 607.5 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 1.22
Marker Score: 5215 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 1.21
Marker Score: 1284 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.21
Marker Score: 11526.5 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 1.21
Marker Score: 456 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.21
Marker Score: 10368 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 1.21
Marker Score: 2137.5 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 1.2
Marker Score: 562 - Cell Name: mononuclear phagocyte (CL0000113)
Fold Change: 1.2
Marker Score: 1207 - Cell Name: cardiac mesenchymal cell (CL0000569)
Fold Change: 1.2
Marker Score: 295 - Cell Name: proerythroblast (CL0000547)
Fold Change: 1.2
Marker Score: 812 - Cell Name: double negative thymocyte (CL0002489)
Fold Change: 1.19
Marker Score: 1645 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.19
Marker Score: 2708.5 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.19
Marker Score: 2797 - Cell Name: mature T cell (CL0002419)
Fold Change: 1.19
Marker Score: 11751 - Cell Name: progenitor cell of endocrine pancreas (CL0002351)
Fold Change: 1.19
Marker Score: 258 - Cell Name: exhausted T cell (CL0011025)
Fold Change: 1.19
Marker Score: 682 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: 1.18
Marker Score: 271 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.18
Marker Score: 352
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Other Information
Genular Protein ID: 2779626072
Symbol: HNRPL_HUMAN
Name: Heterogeneous nuclear ribonucleoprotein L
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11280764
Title: Molecular basis of T cell-mediated recognition of pancreatic cancer cells.
PubMed ID: 11280764
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 2687284
Title: A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts.
PubMed ID: 2687284
PubMed ID: 1286667
Title: Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes.
PubMed ID: 1286667
PubMed ID: 11809897
Title: Human AP-endonuclease 1 and hnRNP-L interact with a nCaRE-like repressor element in the AP-endonuclease 1 promoter.
PubMed ID: 11809897
DOI: 10.1093/nar/30.3.823
PubMed ID: 17289661
Title: Molecular composition of IMP1 ribonucleoprotein granules.
PubMed ID: 17289661
PubMed ID: 18161049
Title: Natural antisense transcript stabilizes inducible nitric oxide synthase messenger RNA in rat hepatocytes.
PubMed ID: 18161049
DOI: 10.1002/hep.22036
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 18669861
Title: Regulation of CD45 alternative splicing by heterogeneous ribonucleoprotein, hnRNPLL.
PubMed ID: 18669861
PubMed ID: 19332550
Title: Heterogeneous nuclear ribonucleoprotein L is a subunit of human KMT3a/Set2 complex required for H3 Lys-36 trimethylation activity in vivo.
PubMed ID: 19332550
PubMed ID: 19124611
Title: Auto- and cross-regulation of the hnRNP L proteins by alternative splicing.
PubMed ID: 19124611
DOI: 10.1128/mcb.01689-08
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22570490
Title: A conserved serine of heterogeneous nuclear ribonucleoprotein L (hnRNP L) mediates depolarization-regulated alternative splicing of potassium channels.
PubMed ID: 22570490
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24164894
Title: Transcriptome-wide RNA interaction profiling reveals physical and functional targets of hnRNP L in human T cells.
PubMed ID: 24164894
DOI: 10.1128/mcb.00740-13
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 25623890
Title: hnRNP L inhibits CD44 V10 exon splicing through interacting with its upstream intron.
PubMed ID: 25623890
PubMed ID: 25772364
Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.
PubMed ID: 25772364
PubMed ID: 26051023
Title: The signature of the five-stranded vRRM fold defined by functional, structural and computational analysis of the hnRNP L protein.
PubMed ID: 26051023
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 33174841
Title: circZNF827 nucleates a transcription inhibitory complex to balance neuronal differentiation.
PubMed ID: 33174841
DOI: 10.7554/elife.58478
PubMed ID: 36537238
Title: CHD8 suppression impacts on histone H3 lysine 36 trimethylation and alters RNA alternative splicing.
PubMed ID: 36537238
DOI: 10.1093/nar/gkac1134
PubMed ID: 23782695
Title: Crystal structures and RNA-binding properties of the RNA recognition motifs of heterogeneous nuclear ribonucleoprotein L: insights into its roles in alternative splicing regulation.
PubMed ID: 23782695
Sequence Information:
- Length: 589
- Mass: 64133
- Checksum: 31EEB51AF1C65F83
- Sequence:
MSRRLLPRAE KRRRRLEQRQ QPDEQRRRSG AMVKMAAAGG GGGGGRYYGG GSEGGRAPKR LKTDNAGDQH GGGGGGGGGA GAAGGGGGGE NYDDPHKTPA SPVVHIRGLI DGVVEADLVE ALQEFGPISY VVVMPKKRQA LVEFEDVLGA CNAVNYAADN QIYIAGHPAF VNYSTSQKIS RPGDSDDSRS VNSVLLFTIL NPIYSITTDV LYTICNPCGP VQRIVIFRKN GVQAMVEFDS VQSAQRAKAS LNGADIYSGC CTLKIEYAKP TRLNVFKNDQ DTWDYTNPNL SGQGDPGSNP NKRQRQPPLL GDHPAEYGGP HGGYHSHYHD EGYGPPPPHY EGRRMGPPVG GHRRGPSRYG PQYGHPPPPP PPPEYGPHAD SPVLMVYGLD QSKMNCDRVF NVFCLYGNVE KVKFMKSKPG AAMVEMADGY AVDRAITHLN NNFMFGQKLN VCVSKQPAIM PGQSYGLEDG SCSYKDFSES RNNRFSTPEQ AAKNRIQHPS NVLHFFNAPL EVTEENFFEI CDELGVKRPS SVKVFSGKSE RSSSGLLEWE SKSDALETLG FLNHYQMKNP NGPYPYTLKL CFSTAQHAS
Genular Protein ID: 708121467
Symbol: Q6NTA2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 572
- Mass: 61927
- Checksum: 5E5EB8F6773DC522
- Sequence:
QRQQPDEQRR RSGAMVKMAA AGGGGGGGRY YGGGSEGGRA PKRLKTDNAG DQHGGGGGGG GGAGAAGGGG GGENYDDPHK TPASPVVHIR GLIDGVVEAD LVEALQEFGP ISYVVVMPKK RQALVEFEDV LGACNAVNYA ADNQIYIAGH PAFVNYSTSQ KISRPGDSDD SRSVNSVLLF TILNPIYSIT TDVLYTICNP CGPVQRIVIF RKNGVQAMVE FDSVQSAQRA KASLNGADIY SGCCTLKIEY AKPTRLNVFK NDQDTWDYTN PNLSGQGDPG SNPNKRQRQP PLLGDHPAEY GGPHGGYHSH YHDEGYGPPP PHYEGRRMGP PVGGHRRGPS RYGPQYGHPP PPPPPPEYGP HADSPVLMVY GLDQSKMNCD RVFNVFCLYG NVEKVKFMKS KPGAAMVEMA DGYAVDRAIT HLNNNFMFGQ KLNVCVSKQP AIMPGQSYGL EDGSCSYKDF SESRNNRFST PEQAAKNRIQ HPSNVLHFFN APLEVTEENF FEICDELGVK RPSSVKVFSG KSERSSSGLL EWESKSDALE TLGFLNHYQM KNPNGPYPYT LKLCFSTAQH AS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.