Details for: AGFG1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 378.3787
Cell Significance Index: -58.8600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 236.1583
Cell Significance Index: -59.9000 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 137.8573
Cell Significance Index: -56.7900 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 131.8090
Cell Significance Index: -62.2300 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 127.0378
Cell Significance Index: -51.6100 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 113.7474
Cell Significance Index: -58.5100 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 54.2450
Cell Significance Index: -51.7900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 48.8075
Cell Significance Index: -60.1800 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 22.2147
Cell Significance Index: -59.5100 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 17.2752
Cell Significance Index: -53.0600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 16.6660
Cell Significance Index: -36.4800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 15.3571
Cell Significance Index: -60.6000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 2.9790
Cell Significance Index: 79.5500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.2788
Cell Significance Index: 457.1200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.1842
Cell Significance Index: 433.4700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.0438
Cell Significance Index: 114.6900 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 1.9810
Cell Significance Index: 29.2400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 1.7353
Cell Significance Index: 3200.3400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.5036
Cell Significance Index: 42.0200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 1.3169
Cell Significance Index: 32.9200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.2394
Cell Significance Index: 444.5600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 1.0897
Cell Significance Index: 73.2700 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.0199
Cell Significance Index: 61.2300 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.0014
Cell Significance Index: 162.8800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.8775
Cell Significance Index: 33.2300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.8488
Cell Significance Index: 1306.7300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.8365
Cell Significance Index: 578.5200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.8275
Cell Significance Index: 63.5000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.7741
Cell Significance Index: 34.2400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.6836
Cell Significance Index: 19.7000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.6786
Cell Significance Index: 83.4500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.5301
Cell Significance Index: 95.5600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.4874
Cell Significance Index: 10.5600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.4093
Cell Significance Index: 369.5600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3847
Cell Significance Index: 210.1100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.3836
Cell Significance Index: 23.5800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.3429
Cell Significance Index: 217.8000 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: 0.3391
Cell Significance Index: 4.2700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.2454
Cell Significance Index: 462.0700 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2122
Cell Significance Index: 93.8000 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.1882
Cell Significance Index: 5.3700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1794
Cell Significance Index: 8.1300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1543
Cell Significance Index: 21.2000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1116
Cell Significance Index: 11.0400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.1025
Cell Significance Index: 139.3800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0798
Cell Significance Index: 15.1900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0669
Cell Significance Index: 30.3600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.0494
Cell Significance Index: 2.3200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0189
Cell Significance Index: 3.2200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0233
Cell Significance Index: -0.4000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0296
Cell Significance Index: -3.4900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0381
Cell Significance Index: -28.2100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0404
Cell Significance Index: -29.6400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0474
Cell Significance Index: -29.5800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0500
Cell Significance Index: -6.4600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0549
Cell Significance Index: -30.9500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0689
Cell Significance Index: -52.1500 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0794
Cell Significance Index: -1.5500 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.0885
Cell Significance Index: -0.5400 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0891
Cell Significance Index: -3.1300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1748
Cell Significance Index: -50.3000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1767
Cell Significance Index: -37.2200 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.1807
Cell Significance Index: -20.6300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1872
Cell Significance Index: -27.2100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1882
Cell Significance Index: -8.7800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.2202
Cell Significance Index: -22.4900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.2217
Cell Significance Index: -14.3000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.2233
Cell Significance Index: -5.7400 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.2443
Cell Significance Index: -4.1200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.2609
Cell Significance Index: -3.5600 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.2808
Cell Significance Index: -2.2900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2935
Cell Significance Index: -34.2000 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.2968
Cell Significance Index: -15.4200 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.2996
Cell Significance Index: -6.5600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3055
Cell Significance Index: -35.0100 - Cell Name: subcutaneous adipocyte (CL0002521)
Fold Change: -0.3101
Cell Significance Index: -1.3500 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.3517
Cell Significance Index: -6.5000 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.3579
Cell Significance Index: -45.8800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.3600
Cell Significance Index: -26.8300 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.3793
Cell Significance Index: -41.2600 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.3867
Cell Significance Index: -27.3500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.4003
Cell Significance Index: -25.2300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.4295
Cell Significance Index: -11.6900 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.4324
Cell Significance Index: -8.9700 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.4563
Cell Significance Index: -47.5100 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.4628
Cell Significance Index: -11.1000 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.4760
Cell Significance Index: -12.7600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.5018
Cell Significance Index: -26.1400 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.6070
Cell Significance Index: -17.4000 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.6188
Cell Significance Index: -8.9000 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.6492
Cell Significance Index: -51.4200 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.6592
Cell Significance Index: -14.0900 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.6657
Cell Significance Index: -9.5600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.8358
Cell Significance Index: -17.8000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.8431
Cell Significance Index: -51.6900 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.9471
Cell Significance Index: -11.8100 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.9483
Cell Significance Index: -14.0000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.0170
Cell Significance Index: -32.3900 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -1.0664
Cell Significance Index: -34.9200 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -1.0689
Cell Significance Index: -56.1200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1587137878
Symbol: AGFG1_HUMAN
Name: Arf-GAP domain and FG repeat-containing protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7634337
Title: Identification of a novel cellular cofactor for the Rev/Rex class of retroviral regulatory proteins.
PubMed ID: 7634337
PubMed ID: 7637788
Title: A human nucleoporin-like protein that specifically interacts with HIV Rev.
PubMed ID: 7637788
DOI: 10.1038/376530a0
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10613896
Title: The eps15 homology (EH) domain-based interaction between eps15 and hrb connects the molecular machinery of endocytosis to that of nucleocytosolic transport.
PubMed ID: 10613896
PubMed ID: 14701878
Title: hRIP, a cellular cofactor for Rev function, promotes release of HIV RNAs from the perinuclear region.
PubMed ID: 14701878
DOI: 10.1101/gad.1149704
PubMed ID: 15749819
Title: The cellular HIV-1 Rev cofactor hRIP is required for viral replication.
PubMed ID: 15749819
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18088087
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22484487
Title: Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning.
PubMed ID: 22484487
DOI: 10.1038/ncb2473
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 562
- Mass: 58260
- Checksum: 9A2242217F53B4D9
- Sequence:
MAASAKRKQE EKHLKMLRDM TGLPHNRKCF DCDQRGPTYV NMTVGSFVCT SCSGSLRGLN PPHRVKSISM TTFTQQEIEF LQKHGNEVCK QIWLGLFDDR SSAIPDFRDP QKVKEFLQEK YEKKRWYVPP EQAKVVASVH ASISGSSASS TSSTPEVKPL KSLLGDSAPT LHLNKGTPSQ SPVVGRSQGQ QQEKKQFDLL SDLGSDIFAA PAPQSTATAN FANFAHFNSH AAQNSANADF ANFDAFGQSS GSSNFGGFPT ASHSPFQPQT TGGSAASVNA NFAHFDNFPK SSSADFGTFN TSQSHQTASA VSKVSTNKAG LQTADKYAAL ANLDNIFSAG QGGDQGSGFG TTGKAPVGSV VSVPSQSSAS SDKYAALAEL DSVFSSAATS SNAYTSTSNA SSNVFGTVPV VASAQTQPAS SSVPAPFGAT PSTNPFVAAA GPSVASSTNP FQTNARGATA ATFGTASMSM PTGFGTPAPY SLPTSFSGSF QQPAFPAQAA FPQQTAFSQQ PNGAGFAAFG QTKPVVTPFG QVAAAGVSSN PFMTGAPTGQ FPTGSSSTNP FL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.