Details for: HSPA9

Gene ID: 3313

Symbol: HSPA9

Ensembl ID: ENSG00000113013

Description: heat shock protein family A (Hsp70) member 9

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 448.2298
    Cell Significance Index: -69.7200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 267.4424
    Cell Significance Index: -67.8400
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 201.6154
    Cell Significance Index: -83.0600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 176.6067
    Cell Significance Index: -83.3800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 174.4954
    Cell Significance Index: -70.8900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 156.2253
    Cell Significance Index: -80.3600
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 124.4072
    Cell Significance Index: -83.4800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 74.8788
    Cell Significance Index: -71.4900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 63.7898
    Cell Significance Index: -78.6500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 25.8991
    Cell Significance Index: -69.3800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 20.5370
    Cell Significance Index: -81.0400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 19.1847
    Cell Significance Index: -58.9300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 12.8325
    Cell Significance Index: -28.0900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 4.9291
    Cell Significance Index: 1418.2400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 3.1386
    Cell Significance Index: 89.9700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.9160
    Cell Significance Index: 79.3700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.8712
    Cell Significance Index: 76.9400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.7099
    Cell Significance Index: 308.2400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.7059
    Cell Significance Index: 338.5400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.6956
    Cell Significance Index: 79.6900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.6812
    Cell Significance Index: 44.8900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.5233
    Cell Significance Index: 187.3000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.5171
    Cell Significance Index: 208.3400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.4554
    Cell Significance Index: 291.9500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.2060
    Cell Significance Index: 62.6500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.0769
    Cell Significance Index: 80.2600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.0436
    Cell Significance Index: 22.6100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.0322
    Cell Significance Index: 73.0100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.0140
    Cell Significance Index: 29.2200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.0039
    Cell Significance Index: 443.8500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.9810
    Cell Significance Index: 126.7400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.9700
    Cell Significance Index: 45.2300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.9633
    Cell Significance Index: 123.4900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.9454
    Cell Significance Index: 516.3000
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 0.8377
    Cell Significance Index: 8.9000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.8090
    Cell Significance Index: 22.6100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.7892
    Cell Significance Index: 35.7700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.7358
    Cell Significance Index: 263.9200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.7259
    Cell Significance Index: 38.1100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.7217
    Cell Significance Index: 25.0800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.6857
    Cell Significance Index: 18.0300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.6852
    Cell Significance Index: 6.3100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.6585
    Cell Significance Index: 77.6600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.6559
    Cell Significance Index: 42.3200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5540
    Cell Significance Index: 33.2600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.5301
    Cell Significance Index: 40.6800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4530
    Cell Significance Index: 408.9900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4468
    Cell Significance Index: 72.6800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.4075
    Cell Significance Index: 69.5900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.4035
    Cell Significance Index: 759.7100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2506
    Cell Significance Index: 173.3100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1622
    Cell Significance Index: 249.6300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1498
    Cell Significance Index: 95.1400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1466
    Cell Significance Index: 270.3900
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.1450
    Cell Significance Index: 3.3500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1366
    Cell Significance Index: 13.5200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1233
    Cell Significance Index: 8.5300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1182
    Cell Significance Index: 22.4900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0943
    Cell Significance Index: 69.1700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0381
    Cell Significance Index: 51.8600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0171
    Cell Significance Index: 7.7800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0166
    Cell Significance Index: 12.5500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0114
    Cell Significance Index: -8.4200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0182
    Cell Significance Index: -1.1500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0184
    Cell Significance Index: -0.5900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0377
    Cell Significance Index: -5.4800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0634
    Cell Significance Index: -6.4800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0766
    Cell Significance Index: -47.8100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1055
    Cell Significance Index: -59.5100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1293
    Cell Significance Index: -4.5500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1743
    Cell Significance Index: -9.7800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1879
    Cell Significance Index: -39.5800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2311
    Cell Significance Index: -26.4800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2314
    Cell Significance Index: -14.2200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.2437
    Cell Significance Index: -5.1000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2663
    Cell Significance Index: -13.8700
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.3003
    Cell Significance Index: -3.5800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3161
    Cell Significance Index: -5.2900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.3179
    Cell Significance Index: -5.3500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3639
    Cell Significance Index: -24.4700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3994
    Cell Significance Index: -46.5500
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.4220
    Cell Significance Index: -48.1800
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.4792
    Cell Significance Index: -5.2100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5562
    Cell Significance Index: -44.0500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.5717
    Cell Significance Index: -7.8000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.6228
    Cell Significance Index: -18.2900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.6496
    Cell Significance Index: -67.6400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.6979
    Cell Significance Index: -17.8300
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.7140
    Cell Significance Index: -17.4200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.7854
    Cell Significance Index: -34.7400
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.8548
    Cell Significance Index: -15.1100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.9386
    Cell Significance Index: -19.9900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -1.0147
    Cell Significance Index: -38.4300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.0707
    Cell Significance Index: -28.6400
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -1.1073
    Cell Significance Index: -6.6900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -1.1470
    Cell Significance Index: -13.0300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.2047
    Cell Significance Index: -73.8600
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -1.2230
    Cell Significance Index: -9.7700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.2609
    Cell Significance Index: -31.5200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.2791
    Cell Significance Index: -32.8800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** HSPA9 is a 75-kDa protein that belongs to the Hsp70 family of heat shock proteins. It is specifically localized to the mitochondria, where it functions as a molecular chaperone to maintain mitochondrial protein quality control. HSPA9 is induced in response to various forms of cellular stress, including heat shock, oxidative stress, and cytokine stimulation. It has been shown to interact with various proteins, including GRP75, which is a mitochondrial glucose-regulated protein. HSPA9 has been implicated in various cellular processes, including erythropoiesis, hematopoiesis, and immune system function. **Pathways and Functions** HSPA9 functions as a molecular chaperone to maintain mitochondrial protein quality control. It is involved in various cellular processes, including: * **Mitochondrial protein folding and refolding**: HSPA9 helps to fold and refold mitochondrial proteins, preventing protein misfolding and aggregation. * **Erythropoiesis and hematopoiesis**: HSPA9 is involved in the regulation of erythropoiesis and hematopoiesis, and its expression is induced in response to erythropoietin stimulation. * **Immune system function**: HSPA9 is involved in the regulation of immune system function, and its expression is induced in response to cytokine stimulation. * **Protein degradation**: HSPA9 is involved in the regulation of protein degradation in the mitochondria, and its expression is induced in response to proteasome inhibition. * **Mitochondrial biogenesis**: HSPA9 is involved in the regulation of mitochondrial biogenesis, and its expression is induced in response to mitochondrial DNA damage. **Clinical Significance** HSPA9 has been implicated in various diseases, including: * **Anemia**: HSPA9 has been shown to play a role in the regulation of erythropoiesis, and its expression is reduced in anemic patients. * **Cancer**: HSPA9 has been shown to play a role in the regulation of immune system function, and its expression is altered in various types of cancer. * **Mitochondrial disorders**: HSPA9 has been shown to play a role in the regulation of mitochondrial function, and its expression is altered in various types of mitochondrial disorders. In summary, HSPA9 is a molecular chaperone that plays a crucial role in maintaining mitochondrial protein quality control and regulating various cellular processes, including erythropoiesis, hematopoiesis, and immune system function. Its expression is induced in response to various forms of cellular stress, and it has been implicated in various diseases, including anemia, cancer, and mitochondrial disorders.

Genular Protein ID: 3781151190

Symbol: GRP75_HUMAN

Name: 75 kDa glucose-regulated protein

UniProtKB Accession Codes:

P38646 B2RCM1 P30036 P31932 Q1HB43 Q53H23 Q6GU03 Q9BWB7 Q9UC56

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 34 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HAMAP 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OGP 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PIR 1 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 7 RefSeq 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7684501

Title: Cloning of the gene encoding peptide-binding protein 74 shows that it is a new member of the heat shock protein 70 family.

PubMed ID: 7684501

DOI: 10.1128/mcb.13.6.3598-3610.1993

PubMed ID: 7829505

Title: Cloning and subcellular localization of human mitochondrial hsp70.

PubMed ID: 7829505

DOI: 10.1074/jbc.270.4.1705

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9150948

Title: A two-dimensional gel database of human colon carcinoma proteins.

PubMed ID: 9150948

DOI: 10.1002/elps.1150180344

PubMed ID: 7498169

Title: Analysis of proteins from human breast epithelial cells using two-dimensional gel electrophoresis.

PubMed ID: 7498169

DOI: 10.1002/elps.11501601202

PubMed ID: 1286669

Title: Human liver protein map: a reference database established by microsequencing and gel comparison.

PubMed ID: 1286669

DOI: 10.1002/elps.11501301201

PubMed ID: 8313870

Title: Human liver protein map: update 1993.

PubMed ID: 8313870

DOI: 10.1002/elps.11501401181

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 17331979

Title: Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones.

PubMed ID: 17331979

DOI: 10.1093/hmg/ddm038

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20668094

Title: Characterization of the human HSC20, an unusual DnaJ type III protein, involved in iron-sulfur cluster biogenesis.

PubMed ID: 20668094

DOI: 10.1093/hmg/ddq301

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21123823

Title: Knockdown of Hspa9, a del(5q31.2) gene, results in a decrease in hematopoietic progenitors in mice.

PubMed ID: 21123823

DOI: 10.1182/blood-2010-06-293167

PubMed ID: 21908771

Title: The first identification of lysine malonylation substrates and its regulatory enzyme.

PubMed ID: 21908771

DOI: 10.1074/mcp.m111.012658

PubMed ID: 22114354

Title: MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization.

PubMed ID: 22114354

DOI: 10.1091/mbc.e11-09-0774

PubMed ID: 22002106

Title: Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization.

PubMed ID: 22002106

DOI: 10.1074/mcp.m111.013680

PubMed ID: 23501103

Title: Tespa1 is a novel component of mitochondria-associated endoplasmic reticulum membranes and affects mitochondrial calcium flux.

PubMed ID: 23501103

DOI: 10.1016/j.bbrc.2013.02.099

PubMed ID: 23541579

Title: Extracellular heat shock protein A9 is a novel interaction partner of podoplanin in oral squamous cell carcinoma cells.

PubMed ID: 23541579

DOI: 10.1016/j.bbrc.2013.03.057

PubMed ID: 23462535

Title: Structural and stability studies of the human mtHsp70-escort protein 1: An essential mortalin co-chaperone.

PubMed ID: 23462535

DOI: 10.1016/j.ijbiomac.2013.02.009

PubMed ID: 23940031

Title: Human mitochondrial chaperone (mtHSP70) and cysteine desulfurase (NFS1) bind preferentially to the disordered conformation, whereas co-chaperone (HSC20) binds to the structured conformation of the iron-sulfur cluster scaffold protein (ISCU).

PubMed ID: 23940031

DOI: 10.1074/jbc.m113.482042

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24625977

Title: Ubiquitin-like (UBX)-domain-containing protein, UBXN2A, promotes cell death by interfering with the p53-Mortalin interactions in colon cancer cells.

PubMed ID: 24625977

DOI: 10.1038/cddis.2014.100

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 26491070

Title: Congenital sideroblastic anemia due to mutations in the mitochondrial HSP70 homologue HSPA9.

PubMed ID: 26491070

DOI: 10.1182/blood-2015-09-659854

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 26598328

Title: Mutations in the heat-shock protein A9 (HSPA9) gene cause the EVEN-PLUS syndrome of congenital malformations and skeletal dysplasia.

PubMed ID: 26598328

DOI: 10.1038/srep17154

PubMed ID: 26634371

Title: Structural studies of UBXN2A and mortalin interaction and the putative role of silenced UBXN2A in preventing response to chemotherapy.

PubMed ID: 26634371

DOI: 10.1007/s12192-015-0661-5

PubMed ID: 26702583

Title: Mitochondrial Hspa9/Mortalin regulates erythroid differentiation via iron-sulfur cluster assembly.

PubMed ID: 26702583

DOI: 10.1016/j.mito.2015.12.005

Sequence Information:

  • Length: 679
  • Mass: 73680
  • Checksum: 90969A8D06757753
  • Sequence:
    • MISASRAAAA RLVGAAASRG PTAARHQDSW NGLSHEAFRL VSRRDYASEA IKGAVVGIDL 
GTTNSCVAVM EGKQAKVLEN AEGARTTPSV VAFTADGERL VGMPAKRQAV TNPNNTFYAT 
KRLIGRRYDD PEVQKDIKNV PFKIVRASNG DAWVEAHGKL YSPSQIGAFV LMKMKETAEN 
YLGHTAKNAV ITVPAYFNDS QRQATKDAGQ ISGLNVLRVI NEPTAAALAY GLDKSEDKVI 
AVYDLGGGTF DISILEIQKG VFEVKSTNGD TFLGGEDFDQ ALLRHIVKEF KRETGVDLTK 
DNMALQRVRE AAEKAKCELS SSVQTDINLP YLTMDSSGPK HLNMKLTRAQ FEGIVTDLIR 
RTIAPCQKAM QDAEVSKSDI GEVILVGGMT RMPKVQQTVQ DLFGRAPSKA VNPDEAVAIG 
AAIQGGVLAG DVTDVLLLDV TPLSLGIETL GGVFTKLINR NTTIPTKKSQ VFSTAADGQT 
QVEIKVCQGE REMAGDNKLL GQFTLIGIPP APRGVPQIEV TFDIDANGIV HVSAKDKGTG 
REQQIVIQSS GGLSKDDIEN MVKNAEKYAE EDRRKKERVE AVNMAEGIIH DTETKMEEFK 
DQLPADECNK LKEEISKMRE LLARKDSETG ENIRQAASSL QQASLKLFEM AYKKMASERE 
GSGSSGTGEQ KEDQKEEKQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.