Details for: IFIT3
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 137.9663
Cell Significance Index: -21.4600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 83.4242
Cell Significance Index: -21.1600 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 49.0330
Cell Significance Index: -19.9200 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 47.5194
Cell Significance Index: -22.4400 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 43.9262
Cell Significance Index: -22.6000 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 20.9899
Cell Significance Index: -20.0400 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 17.9650
Cell Significance Index: -22.1500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 8.1266
Cell Significance Index: -21.7700 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 5.7577
Cell Significance Index: -22.7200 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 3.6117
Cell Significance Index: 188.1300 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 2.7443
Cell Significance Index: 48.5000 - Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: 2.4084
Cell Significance Index: 20.7000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 2.0714
Cell Significance Index: 394.2000 - Cell Name: decidual cell (CL2000002)
Fold Change: 1.6306
Cell Significance Index: 26.1600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.0504
Cell Significance Index: 22.3700 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.7478
Cell Significance Index: 11.5700 - Cell Name: peg cell (CL4033014)
Fold Change: 0.7410
Cell Significance Index: 17.1200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.7016
Cell Significance Index: 42.1200 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6073
Cell Significance Index: 98.7700 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.5239
Cell Significance Index: 67.1600 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.4945
Cell Significance Index: 9.1400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4690
Cell Significance Index: 46.3900 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.4007
Cell Significance Index: 80.3800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.3798
Cell Significance Index: 26.2700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.3634
Cell Significance Index: 49.9000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.3572
Cell Significance Index: 322.5400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.3327
Cell Significance Index: 17.4700 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.2256
Cell Significance Index: 306.7300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.2223
Cell Significance Index: 342.2600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2154
Cell Significance Index: 77.2700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.2134
Cell Significance Index: 13.1200 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 0.1951
Cell Significance Index: 2.9400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.1767
Cell Significance Index: 20.5900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.1708
Cell Significance Index: 8.8700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.1652
Cell Significance Index: 3.5800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.1166
Cell Significance Index: 215.0400 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.0642
Cell Significance Index: 4.1400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0456
Cell Significance Index: 1.1400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0424
Cell Significance Index: 18.7600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0393
Cell Significance Index: 7.0900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0366
Cell Significance Index: 19.9900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0339
Cell Significance Index: 5.7900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0328
Cell Significance Index: 6.5100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.0295
Cell Significance Index: 3.3800 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0205
Cell Significance Index: 0.5500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0196
Cell Significance Index: 36.8900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0170
Cell Significance Index: 10.8200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0153
Cell Significance Index: 1.8800 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0099
Cell Significance Index: 6.8600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.0099
Cell Significance Index: 0.2700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0012
Cell Significance Index: 0.0200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0063
Cell Significance Index: -0.2200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0070
Cell Significance Index: -5.1400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0076
Cell Significance Index: -5.6300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0077
Cell Significance Index: -4.8300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0150
Cell Significance Index: -1.5300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0181
Cell Significance Index: -10.2000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0200
Cell Significance Index: -15.1400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0287
Cell Significance Index: -8.2700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0332
Cell Significance Index: -2.2300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0388
Cell Significance Index: -17.6300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0459
Cell Significance Index: -9.6700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0461
Cell Significance Index: -2.0900 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.0463
Cell Significance Index: -0.2800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0642
Cell Significance Index: -1.8500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0874
Cell Significance Index: -12.7100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0897
Cell Significance Index: -10.2400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0938
Cell Significance Index: -1.5700 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.0947
Cell Significance Index: -1.1800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1338
Cell Significance Index: -17.2900 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1674
Cell Significance Index: -11.8400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1834
Cell Significance Index: -21.6300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.2022
Cell Significance Index: -5.6500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2114
Cell Significance Index: -22.0100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.2362
Cell Significance Index: -18.1300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2438
Cell Significance Index: -19.3100 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2516
Cell Significance Index: -18.7500 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.2565
Cell Significance Index: -2.6600 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.2594
Cell Significance Index: -6.2200 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2784
Cell Significance Index: -13.0900 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.2892
Cell Significance Index: -3.2900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.3247
Cell Significance Index: -15.1400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.3412
Cell Significance Index: -8.7700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.3677
Cell Significance Index: -22.5400 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.3743
Cell Significance Index: -10.7300 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.3891
Cell Significance Index: -10.3900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3903
Cell Significance Index: -24.6000 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: -0.3928
Cell Significance Index: -5.4500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3956
Cell Significance Index: -12.6700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.3979
Cell Significance Index: -22.3300 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.4130
Cell Significance Index: -10.5500 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.4585
Cell Significance Index: -6.8700 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.4614
Cell Significance Index: -7.3200 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.4666
Cell Significance Index: -12.2700 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.4847
Cell Significance Index: -16.9800 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.4848
Cell Significance Index: -14.2800 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.4980
Cell Significance Index: -15.7500 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.5068
Cell Significance Index: -25.6100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.5116
Cell Significance Index: -22.6300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.5263
Cell Significance Index: -18.2900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1260536774
Symbol: IFIT3_HUMAN
Name: Interferon-induced protein with tetratricopeptide repeats 3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9391139
Title: Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: induction of interferon-responsive RNAs.
PubMed ID: 9391139
PubMed ID: 9828129
Title: IFI60/ISG60/IFIT4, a new member of the human IFI54/IFIT2 family of interferon-stimulated genes.
PubMed ID: 9828129
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17050680
Title: RIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteins.
PubMed ID: 17050680
PubMed ID: 18706081
Title: Interferon-induced protein IFIT4 is associated with systemic lupus erythematosus and promotes differentiation of monocytes into dendritic cell-like cells.
PubMed ID: 18706081
DOI: 10.1186/ar2475
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 20686046
Title: Identification of alpha interferon-induced genes associated with antiviral activity in Daudi cells and characterization of IFIT3 as a novel antiviral gene.
PubMed ID: 20686046
DOI: 10.1128/jvi.00818-10
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21190939
Title: The interferon stimulated gene 54 promotes apoptosis.
PubMed ID: 21190939
PubMed ID: 21813773
Title: IFN-induced TPR protein IFIT3 potentiates antiviral signaling by bridging MAVS and TBK1.
PubMed ID: 21813773
PubMed ID: 20950130
PubMed ID: 21642987
Title: IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA.
PubMed ID: 21642987
DOI: 10.1038/ni.2048
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 490
- Mass: 55985
- Checksum: B9F042D4DF7151D2
- Sequence:
MSEVTKNSLE KILPQLKCHF TWNLFKEDSV SRDLEDRVCN QIEFLNTEFK ATMYNLLAYI KHLDGNNEAA LECLRQAEEL IQQEHADQAE IRSLVTWGNY AWVYYHLGRL SDAQIYVDKV KQTCKKFSNP YSIEYSELDC EEGWTQLKCG RNERAKVCFE KALEEKPNNP EFSSGLAIAM YHLDNHPEKQ FSTDVLKQAI ELSPDNQYVK VLLGLKLQKM NKEAEGEQFV EEALEKSPCQ TDVLRSAAKF YRRKGDLDKA IELFQRVLES TPNNGYLYHQ IGCCYKAKVR QMQNTGESEA SGNKEMIEAL KQYAMDYSNK ALEKGLNPLN AYSDLAEFLE TECYQTPFNK EVPDAEKQQS HQRYCNLQKY NGKSEDTAVQ HGLEGLSISK KSTDKEEIKD QPQNVSENLL PQNAPNYWYL QGLIHKQNGD LLQAAKCYEK ELGRLLRDAP SGIGSIFLSA SELEDGSEEM GQGAVSSSPR ELLSNSEQLN
Genular Protein ID: 302540400
Symbol: A0A7P0T7D6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 438
- Mass: 49826
- Checksum: 257688E40B456377
- Sequence:
MYNLLAYIKH LDGNNEAALE CLRQAEELIQ QEHADQAEIR SLVTWGNYAW VYYHLGRLSD AQIYVDKVKQ TCKKFSNPYS IEYSELDCEE GWTQLKCGRN ERAKVCFEKA LEEKPNNPEF SSGLAIAMYH LDNHPEKQFS TDVLKQAIEL SPDNQYVKVL LGLKLQKMNK EAEGEQFVEE ALEKSPCQTD VLRSAAKFYR RKGDLDKAIE LFQRVLESTP NNGYLYHQIG CCYKAKVRQM QNTGESEASG NKEMIEALKQ YAMDYSNKAL EKGLNPLNAY SDLAEFLETE CYQTPFNKEV PDAEKQQSHQ RYCNLQKYNG KSEDTAVQHG LEGLSISKKS TDKEEIKDQP QNVSENLLPQ NAPNYWYLQG LIHKQNGDLL QAAKCYEKEL GRLLRDAPSG IGSIFLSASE LEDGSEEMGQ GAVSSSPREL LSNSEQLN
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.